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  1. Article ; Online: The surgeon and the COVID-19 pandemic.

    Verzaro, Roberto / Nishida, Seigo

    International journal of surgery (London, England)

    2020  Volume 78, Page(s) 160–161

    Keywords covid19
    Language English
    Publishing date 2020-05-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2020.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The surgeon and the COVID-19 pandemic

    Verzaro, Roberto / Nishida, Seigo

    International Journal of Surgery

    2020  Volume 78, Page(s) 160–161

    Keywords Surgery ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2212038-5
    ISSN 1743-9191
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2020.05.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Identification of anaplastic lymphoma kinase fusion in clear cell renal carcinoma (ALK-tRCC): a precision oncology medicine case report.

    Varchetta, Veronica / Campanella, Carla / Rossi, Michele / Verzaro, Roberto / Vitale, Marco / Soda, Giuseppe / Mancuso, Andrea

    Recenti progressi in medicina

    2021  Volume 112, Issue 1, Page(s) 14e–15e

    Abstract: Background: Translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) is a rare subtype of adult renal cell carcinoma (RCC) reported in recent years.: Case presentation: A new Italian case of ALK-tRCC was reported. The patient was a ... ...

    Abstract Background: Translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) is a rare subtype of adult renal cell carcinoma (RCC) reported in recent years.
    Case presentation: A new Italian case of ALK-tRCC was reported. The patient was a female 44-year-old with a metastatic and pretreated RCC. The tumor showed a rearrangement of ALK gene in tumor cells detected by targeted next-generation sequencing panel. The patient received oral alectinib therapy and achieved a partial response.
    Conclusions: ALK-tRCC is a rare subtype of adult RCC. Its diagnosis is very difficult because the genomic alteration spectrum is very wide. We suggested that metastatic RCCs should be screened for uncommon genomic alterations expecially in good performance status pretreated resistant/refractory patients.
    MeSH term(s) Adult ; Anaplastic Lymphoma Kinase/genetics ; Carcinoma, Renal Cell/diagnosis ; Carcinoma, Renal Cell/drug therapy ; Carcinoma, Renal Cell/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/drug therapy ; Kidney Neoplasms/genetics ; Precision Medicine
    Chemical Substances Anaplastic Lymphoma Kinase (EC 2.7.10.1)
    Language English
    Publishing date 2021-01-29
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 138266-4
    ISSN 2038-1840 ; 0034-1193
    ISSN (online) 2038-1840
    ISSN 0034-1193
    DOI 10.1701/3525.35133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pulmonary tumor embolization as early manifestation in patients with renal cell carcinoma and tumor thrombus: Perioperative management and outcomes.

    Serena, Giuseppe / Gonzalez, Javier / Gaynor, Jeffrey J / Salerno, Tomas / Verzaro, Roberto / Ciancio, Gaetano

    Journal of cardiac surgery

    2019  Volume 34, Issue 10, Page(s) 1018–1023

    Abstract: Background: Renal cell carcinoma (RCC) with tumor thrombus extending into the inferior vena cava (IVC) occurs in 4%-10% of cases. Within this subset, pulmonary tumor embolism (PTE) appears in approximately 0.9%-2.4% of cases. We wanted to review our ... ...

    Abstract Background: Renal cell carcinoma (RCC) with tumor thrombus extending into the inferior vena cava (IVC) occurs in 4%-10% of cases. Within this subset, pulmonary tumor embolism (PTE) appears in approximately 0.9%-2.4% of cases. We wanted to review our experience in managing patients with RCC with IVC involvement and a preoperative diagnosis of PTE.
    Methods: A total of seven patients presented at our center between January, 2005 and January, 2015 with RCC, IVC involvement, and PTE (diagnosed either by chest computerized tomography angiography or preoperative transesophageal echocardiogram). Each patient underwent a radical nephrectomy and tumor thrombectomy using an organ transplant-based approach.
    Results: Surgical removal of the PTE was performed in three patients (tumor embolectomy in two cases, right lower lobe resection in one case); the PTEs in four patients were considered to be too small to undergo surgical resection. PTE pathology found neoplastic cells in each patient that had surgical removal. No postoperative complications were observed in any of the seven patients. All four patients who were metastasis-free preoperatively (with 2/4 having tumor embolectomy performed) developed distant metastasis; median time-to-developing metastatic disease was 6.5 months. With a median follow-up of 19 months, three deaths because the disease have occurred.
    Conclusion: Although RCC with IVC tumor thrombus complicated by PTE may not be catastrophic in most cases, it appears to be associated with an increased risk of developing metastatic disease. In addition, as the PTEs appear to contain neoplastic cells, pulmonary artery embolectomy at the time of nephrectomy should be performed whenever possible.
    MeSH term(s) Adult ; Aged ; Carcinoma, Renal Cell/complications ; Carcinoma, Renal Cell/diagnosis ; Embolectomy/methods ; Female ; Follow-Up Studies ; Humans ; Kidney Neoplasms/complications ; Kidney Neoplasms/diagnosis ; Male ; Middle Aged ; Neoplastic Cells, Circulating ; Nephrectomy ; Perioperative Period ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/etiology ; Pulmonary Embolism/surgery ; Retrospective Studies ; Thrombectomy/methods ; Tomography, X-Ray Computed ; Vena Cava, Inferior ; Venous Thrombosis/diagnosis ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery
    Language English
    Publishing date 2019-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.14182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Radical surgery for gastric cancer in octogenarian patients.

    Casella, Francesco / Sansonetti, Andrea / Zanoni, Andrea / Vincenza, Cofini / Capodacqua, Alberto / Verzaro, Roberto

    Updates in surgery

    2017  Volume 69, Issue 3, Page(s) 389–395

    Abstract: To valuate feasibility and results of radical surgery in octogenarian patients with gastric cancer. We collected data on 60 patients that underwent gastrectomy with an R0 resection at our Institution from 2010 to 2015. Patients were divided into two ... ...

    Abstract To valuate feasibility and results of radical surgery in octogenarian patients with gastric cancer. We collected data on 60 patients that underwent gastrectomy with an R0 resection at our Institution from 2010 to 2015. Patients were divided into two groups: octogenarian (OG) (n = 26), consisting of patients aged 80-89 years, and younger (YG) (n = 34), consisting of patients under 80 years of age. All patients were treated with total or subtotal gastrectomy with lymphadenectomy. A D2-lymphadenectomy was performed in 11 and 24 patients, a D1+ in 5 and 4, a D1 in 8 and 6, and a D0 in 2 and 0 cases in OG and YG respectively. The overall morbidity rate was 42.3% (11/26) in OG and 29.4% (10/34) in YG, while 90-days mortality was observed in four (15.4%) and one (2.9%) patients in OG and YG, respectively. The median hospital stay was 9 days (2-31) and 9.5 days (6-66) in OG and YG, respectively. Gastrectomy with radical resection and limited lymphadenectomy should be recommended for octogenarian patients with good performance status and low co-morbidity.
    MeSH term(s) Adenocarcinoma/mortality ; Adenocarcinoma/surgery ; Age Factors ; Aged, 80 and over ; Feasibility Studies ; Female ; Follow-Up Studies ; Gastrectomy ; Humans ; Lymph Node Excision ; Male ; Postoperative Complications/epidemiology ; Retrospective Studies ; Stomach Neoplasms/mortality ; Stomach Neoplasms/surgery ; Survival Analysis ; Treatment Outcome
    Language English
    Publishing date 2017-05-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-017-0463-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Metastatic lesions to the liver.

    Ortiz, Jorge / Imagawa, David K / Verzaro, Roberto / Serafini, Francesco / Kayler, Liise K

    International journal of hepatology

    2013  Volume 2013, Page(s) 104365

    Language English
    Publishing date 2013-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2621468-4
    ISSN 2090-3456 ; 2090-3448
    ISSN (online) 2090-3456
    ISSN 2090-3448
    DOI 10.1155/2013/104365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Selection Bias in Colorectal Surgery in a Non-Tertiary Hospital: Laparoscopic Versus Open Surgery.

    Verzaro, Roberto / Mattia, Simona / Rago, Teresa / Casella, Francesco / Ferroni, Andrea / Gianfreda, Valeria / Cofini, Vincenza / Necozione, Stefano

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2017  Volume 28, Issue 3, Page(s) 263–268

    Abstract: Introduction: Laparoscopy is used increasingly to treat malignant and benign colorectal surgical diseases. However, this practice is still not offered to all patients. Many barriers halt the widespread use of laparoscopic colorectal surgery. Both ... ...

    Abstract Introduction: Laparoscopy is used increasingly to treat malignant and benign colorectal surgical diseases. However, this practice is still not offered to all patients. Many barriers halt the widespread use of laparoscopic colorectal surgery. Both surgeon's and patient's factors contribute to limit a wider use of laparoscopy in colorectal surgery.
    Materials and methods: We retrospectively analyzed 408 consecutive colorectal resections in a 4-year period, to find out if a selection bias exists in using laparotomy or laparoscopy for colorectal surgical diseases, and which factors are associated with a poor use of laparoscopy or to a preferred laparotomy.
    Results: In our practice, advanced disease, American Society of Anesthesiologist class III and IV, and emergency status are all patient-related factors associated with laparotomy. Surgeon's age more than 52 years and lack of laparoscopic training are surgeon-related factors that negatively affect the chance of being operated on with the laparoscopic technique.
    Conclusions: An extensive laparoscopic colorectal training and a supporting environment, especially during the night shift, are needed to facilitate the use of laparoscopy in colorectal surgery avoiding a bias in selecting surgical candidates to one technique or another.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; Clinical Competence ; Colonic Diseases/surgery ; Colorectal Surgery/education ; Colorectal Surgery/statistics & numerical data ; Emergencies ; Female ; Health Status ; Humans ; Laparoscopy/education ; Laparoscopy/statistics & numerical data ; Male ; Middle Aged ; Patient Selection ; Rectal Diseases/surgery ; Retrospective Studies ; Selection Bias
    Language English
    Publishing date 2017-12-05
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2608063-1
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2017.0174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Use of circular stapler for enteric drainage of the pancreatic graft.

    Verzaro, Roberto / de Simone, Paolo

    Journal of the American College of Surgeons

    2004  Volume 199, Issue 3, Page(s) 518

    MeSH term(s) Anastomosis, Surgical/instrumentation ; Drainage/instrumentation ; Duodenum/surgery ; Enterostomy ; Equipment Design ; Humans ; Pancreas Transplantation/instrumentation ; Surgical Staplers ; Surgical Stapling/instrumentation ; Surgical Stapling/methods
    Language English
    Publishing date 2004-09
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1016/j.jamcollsurg.2004.05.261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Toward "no age limit" for liver transplant donors.

    Verzaro, Roberto / Minervini, Marta / Gridelli, Bruno

    Transplantation

    2008  Volume 85, Issue 12, Page(s) 1869–1870

    MeSH term(s) Age Factors ; Aged, 80 and over ; Carcinoma, Hepatocellular/surgery ; Hepatitis C/surgery ; Humans ; Liver Function Tests ; Liver Neoplasms/surgery ; Liver Transplantation/physiology ; Middle Aged ; Tissue Donors
    Language English
    Publishing date 2008-06-27
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0b013e31817b00c2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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