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  1. Article ; Online: Robotic-assisted surgery for gynecological indications in children and adolescents: European multicenter report.

    Esposito, Ciro / Blanc, Thomas / Di Mento, Claudia / Ballouhey, Quentin / Fourcade, Laurent / Mendoza-Sagaon, Mario / Chiodi, Annalisa / Cardone, Roberto / Escolino, Maria

    Journal of robotic surgery

    2024  Volume 18, Issue 1, Page(s) 20

    Abstract: Robotic-assisted surgery (RAS) is increasingly adopted in the pediatric population. This retrospective multicenter study aimed to report application of RAS for gynecological indications in pediatric patients. The medical records of all girls with ... ...

    Abstract Robotic-assisted surgery (RAS) is increasingly adopted in the pediatric population. This retrospective multicenter study aimed to report application of RAS for gynecological indications in pediatric patients. The medical records of all girls with gynecological pathology, operated in 4 different institutions over a 3-year period, were retrospectively collected. Robot docking time, total operative time, length of stay (LOS), requirement time of pain medication, complication rate, conversion rate, and pathology were analyzed. Twenty-three girls, with median age of 12.3 years (range 0.6-17.8) and median weight of 47.2 kg (range 9-73), received the following RAS procedures: ovarian cystectomy for ovarian cyst/mass (n = 10), salpingo-oophorectomy for ovarian complex mass (n = 6), bilateral gonadectomy for Turner syndrome SRY + (n = 1), salpingectomy for fallopian tube lesion (n = 1), paratubal cyst excision (n = 1), Gartner cyst excision (n = 1), paravaginal ganglioneuroma resection (n = 1), fistula closure in urogenital sinus (n = 1), and vaginoplasty using ileal flap in cloaca malformation (n = 1). Median operative time was 144.9 min (range 64-360), and median docking time was 17.3 min (range 7-50). Conversion to open or laparoscopy was not necessary in any case. Median LOS was 2.1 days (range 1-7), and median analgesic requirement was 2.2 days (range 1-6). One patient (4.3%) needed redo-surgery for recurrent Gartner cyst (Clavien 3b). This preliminary experience showed that RAS is safe and feasible for surgical treatment of gynecological pathology in pediatric patients, although no conclusive data are available to confirm its superiority over traditional laparoscopy. Randomized, prospective, comparative studies are needed to identify the gold standard approach for such indication.
    MeSH term(s) Female ; Humans ; Child ; Adolescent ; Infant ; Child, Preschool ; Robotic Surgical Procedures/methods ; Retrospective Studies ; Prospective Studies ; Laparoscopy ; Cysts ; Treatment Outcome
    Language English
    Publishing date 2024-01-13
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-023-01767-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A prospective study to evaluate the contribution of the pediatric appendicitis score in the decision process.

    Vevaud, Kevin / Dallocchio, Aymeric / Dumoitier, Nathalie / Laspougeas, Alban / Labrunie, Anaïs / Belgacem, Alexis / Fourcade, Laurent / Ballouhey, Quentin

    BMC pediatrics

    2024  Volume 24, Issue 1, Page(s) 131

    Abstract: Background: The objective of this study was to assess the likelihood of acute appendicitis (AA) in children presenting with abdominal symptoms at the emergency department (ED), based on their prior primary care (PC) consultation history.: Methods: ... ...

    Abstract Background: The objective of this study was to assess the likelihood of acute appendicitis (AA) in children presenting with abdominal symptoms at the emergency department (ED), based on their prior primary care (PC) consultation history.
    Methods: Between February and June 2021, we prospectively enrolled all children presenting at the ED with acute abdominal pain indicative of possible acute appendicitis (AA). Subsequently, they were categorized into three groups: those assessed by a PC physician (PG), those brought in by their family without a prior consultation (FG), and those admitted after a PC consultation without being assessed as such. The primary objective was to assess the probability of AA diagnosis using the Pediatric Appendicitis Score (PAS). Secondary objectives included analyzing PAS and C-reactive protein (CRP) levels based on the duration of pain and final diagnoses.
    Results: 124 children were enrolled in the study (PG, n = 56; FG, n = 55; NG, n = 13). Among them, 29 patients (23.4%) were diagnosed with AA, with 13 cases (23.2%) from the PG and 14 cases (25.4%) from the FG. The mean PAS scores for AA cases from the PG and FG were 6.69 ± 1.75 and 7.57 ± 1.6, respectively, (p = 0.3340). Both PAS scores and CRP levels showed a significant correlation with AA severity. No cases of AA were observed with PAS scores < 4.
    Conclusions: There was no significant difference in PAS scores between patients addressed by PG and FG, even though PAS scores tended to be higher for patients with AA. We propose a new decision-making algorithm for PC practice, which incorporates inflammatory markers and pain duration.
    Trial registration: Institutional Ethics Committee registration number: 447-2021-103 (10/01/2021).
    Clinical trials registration number: ClinicalTrials.gov Identifier: NCT04885335 (Registered on 13/05/2021).
    MeSH term(s) Child ; Humans ; Appendicitis/diagnosis ; Appendicitis/complications ; Prospective Studies ; Abdominal Pain/etiology ; Abdominal Pain/complications ; Leukocyte Count ; Abdomen, Acute ; Acute Disease ; Sensitivity and Specificity
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-024-04619-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Evaluation of surgical outcomes of calcaneonavicular coalition and too-long anterior process in children: A prospective study.

    Lescot, Timothé / Compagnon, Roxane / Accadbled, Franck / Sales de Gauzy, Jérôme / Mouliès, Dominique / Mihluedo, Louis / Fourcade, Laurent / Ballouhey, Quentin

    Orthopaedics & traumatology, surgery & research : OTSR

    2023  , Page(s) 103620

    Abstract: Introduction: Calcaneonavicular coalitions (CC) affect approximately 1% of the general population. CC or Too-long anterior process (TLAP) result in "repeated sprains" that can be associated with foot and/or ankle chronic pain. The main objective of this ...

    Abstract Introduction: Calcaneonavicular coalitions (CC) affect approximately 1% of the general population. CC or Too-long anterior process (TLAP) result in "repeated sprains" that can be associated with foot and/or ankle chronic pain. The main objective of this study was to analyze the effectiveness of surgery using the AOFAS score.
    Hypothesis: Functional results after surgical treatment of CC or TLAP are not as good as expected.
    Materials and methods: A single-center prospective study was carried out at our University Hospital from 01/01/2019 to 06/01/2021. The patients included were operated on in the pediatric surgery department for CC or TLAP resection by direct approach after MRI confirmation and failure of non-operative treatment. A survey evaluating the AOFAS score as well as the number of ankle sprains and the intensity of pain was undertaken at the preoperative consultation and then at three and twelve months postoperatively.
    Results: A total of 17 feet in 16 patients (14 girls and 2 boys) comprising 12 TLAP and 5 CC were included. The AOFAS score was statistically significantly increased (58.6 vs. 82.9; p<0.001) postoperatively. No statistical difference was noted between the follow-up visits at three and twelve months. At the twelve-month follow-up, 9 out of 16 patients (56.2%) still reported activity restrictions; mainly linked to the persistence of chronic pain, and 10 out of 16 patients (62.5%) reported a feeling of instability.
    Discussion: CC and TLAP surgery rapidly improves function but it does not dramatically reduce foot pain and activity restrictions. A dedicated score would be useful to identify patients who will benefit the most from surgery.
    Level of evidence: IV; prospective study.
    Language English
    Publishing date 2023-04-11
    Publishing country France
    Document type Journal Article
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2023.103620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Efficiency of non-operative management for pectus deformities in children using an X-ray-free protocol.

    Belgacem, Alexis / Tricard, Jérémy / Dutoit, Alexandre / Grosos, Céline / Auditeau, Emilie / Masselin, Mathilde Casson / Fourcade, Laurent / Ballouhey, Quentin

    Interdisciplinary cardiovascular and thoracic surgery

    2023  Volume 36, Issue 6

    Abstract: Objectives: The aim of this study was to explore the correlation between the Haller index (HI), the external depth of protrusion and the external Haller index (EHI) for both pectus excavatum (PE) and pectus carinatum (PC) and to assess the variation in ... ...

    Abstract Objectives: The aim of this study was to explore the correlation between the Haller index (HI), the external depth of protrusion and the external Haller index (EHI) for both pectus excavatum (PE) and pectus carinatum (PC) and to assess the variation in the HI during this first year of non-operative treatment for pectus deformities in children.
    Methods: From January 2018 to December 2022, all children treated for PE by vacuum bell and for PC by compression therapy at our institution were evaluated by external gauge, 3D scanning (iPad with Structure Sensor and Captevia-Rodin4D) and magnetic resonance imaging (MRI). The main objectives were to assess the effectiveness of the treatment during the first year and to compare the HI determined by MRI to the EHI evaluated with 3D scanning and external measurements. The HI determined by MRI was compared to the EHI evaluated with 3D scanning and external measurements at M0 and M12.
    Results: A total of 118 patients (80 PE and 38 PC) had been referred for pectus deformity. Of these, 79 met the inclusion criteria (median age 13.7 years, 8.6-17.8). There was a statistically significant difference in the external measurements of the depth for PE between M0 and M12: 23.0 ± 7.2 vs 13.8 ± 6.1 mm, respectively, P < 0.05, and for PC 31.1 ± 10.6 vs 16.7 ± 8.9 mm, respectively, P < 0.01. During this first year of treatment, the reduction in the external measurement increased more rapidly for PE compared with PC. We found a strong correlation between the HI by MRI and the EHI by 3D scanning for PE (Pearson coefficient = 0.910, P < 0.001) and for PC (Pearson coefficient = 0.934, P < 0.001). A correlation between the EHI by 3D scanning and the external measurements by profile gauge was found for PE (Pearson coefficient = 0.663, P < 0.001) but not for PC.
    Conclusions: Excellent results were observed as soon as the sixth month for both PE and PC. Measurement of protrusion is a reliable monitoring tool at clinical consultation but caution is required for PC as it does not appear to be correlated to the HI by MRI.
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivad093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hemolytic uremic syndrome following complicated appendicitis in a child: what is the missing link?

    Belgacem, Alexis / Miane, Hortense / Fillali, Wasfi / Hangard, Pauline / Ponthier, Laure / Ballouhey, Quentin

    The Journal of international medical research

    2021  Volume 49, Issue 4, Page(s) 3000605211006952

    Abstract: We herein describe an 18-month-old boy who underwent initially successful surgical and antibiotic treatment of complicated appendicitis with postoperative occurrence of hemolytic uremic syndrome (HUS). This complication was due to Shiga toxin- ... ...

    Abstract We herein describe an 18-month-old boy who underwent initially successful surgical and antibiotic treatment of complicated appendicitis with postoperative occurrence of hemolytic uremic syndrome (HUS). This complication was due to Shiga toxin-producing
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Appendicitis/complications ; Appendicitis/surgery ; Child ; Escherichia coli Infections/drug therapy ; Hemolytic-Uremic Syndrome/drug therapy ; Hemolytic-Uremic Syndrome/etiology ; Humans ; Infant ; Male ; Shiga-Toxigenic Escherichia coli
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/03000605211006952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply by the Authors.

    Ballouhey, Quentin / Fourcade, Laurent / Descazeaud, Aurélien / Guigonis, Vincent

    Urology

    2016  Volume 97, Page(s) 279

    Language English
    Publishing date 2016-11
    Publishing country United States
    Document type Letter
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2016.06.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pediatric robot-assisted extravesical ureteral reimplantation (revur) in simple and complex ureter anatomy: Report of a multicenter experience.

    Esposito, Ciro / Masieri, Lorenzo / Fourcade, Laurent / Ballouhey, Quentin / Varlet, Francois / Scalabre, Aurelien / Castagnetti, Marco / El Ghoneimi, Alaa / Escolino, Maria

    Journal of pediatric urology

    2022  Volume 19, Issue 1, Page(s) 136.e1–136.e7

    Abstract: Background: Robot-assisted extravesical ureteral reimplantation (REVUR) is a well established approach for surgical treatment of pediatric vesicoureteral reflux (VUR). However, further evidence is needed to confirm its efficacy even in case of complex ... ...

    Abstract Background: Robot-assisted extravesical ureteral reimplantation (REVUR) is a well established approach for surgical treatment of pediatric vesicoureteral reflux (VUR). However, further evidence is needed to confirm its efficacy even in case of complex anatomy.
    Objective: This study aimed to further confirm the evidence that REVUR is safe and effective in both simple and complex ureter anatomy.
    Study design: The charts of all patients with VUR, who received REVUR in 6 different institutions over a 5-year period, were retrospectively reviewed. Patients with both simple and complex ureter anatomy were included. Patient demographics, surgical variables, and post-operative results were assessed. VUR resolution was defined as either being resolved VUR on voiding cystourethrogram (VCUG) or clinically without symptoms during the follow-up.
    Results: Fifty-seven patients with median age of 6.9 years (range 4.5-12), receiving REVUR in the study period, were included. Eighteen (31.6%) patients had complex anatomy and included prior failed endoscopic injection (n = 13), complete ureteral duplication (n = 2), periureteral diverticulum (n = 2), ectopic megaureter requiring dismembering (n = 1). The median operative time was 155 min for unilateral and 211.5 min for bilateral repairs. The clinical + radiographic VUR resolution rate was 96.5%. Post-operative complications (Clavien 2) included urinary retention following bilateral repair (n = 5, 8.7%), febrile urinary tract infection (UTI) (n = 6, 10.5%) and gross hematuria (n = 3, 5.2%). Comparative analysis between simple and complex cases showed that REVUR was faster in simple cases in both unilateral [p = 0.002] and bilateral repair [p = 0.001] and post-operative urinary retention was more frequent in simple cases [p = 0.004] and in patients with pre-operative bowel and bladder dysfunction (BBD) [p = 0.001] (Table).
    Discussion: This series confirmed that the robot-assisted technique was feasible even in cases with complex anatomy using some technical refinements, that justified the longer operative times in both unilateral and bilateral cases. An interesting finding of this study was the correlation emerged between BBD and risk of post-operative urinary retention and VUR persistence. Our results also excluded any significant correlation between complex cases and risk of post-operative urinary retention. The main study limitations included the retrospective and nonrandomized design, the small number of cases and the arbitrary definition of complex anatomy.
    Conclusion: REVUR was safe and effective for management of VUR in both simple and complex ureter anatomy. Complex REVUR required slightly longer operative times, without significant differences in post-operative mordidity and success rates. Aside from complex anatomy, BBD emerged as the main risk factor associated with surgical failure and post-operative morbidity.
    MeSH term(s) Humans ; Child ; Child, Preschool ; Ureter/surgery ; Retrospective Studies ; Urinary Retention ; Robotics ; Treatment Outcome ; Robotic Surgical Procedures/methods ; Laparoscopy/methods ; Vesico-Ureteral Reflux/surgery ; Replantation/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery
    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2022.10.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hemolytic uremic syndrome following complicated appendicitis in a child

    Alexis Belgacem / Hortense Miane / Wasfi Fillali / Pauline Hangard / Laure Ponthier / Quentin Ballouhey

    Journal of International Medical Research, Vol

    what is the missing link?

    2021  Volume 49

    Abstract: We herein describe an 18-month-old boy who underwent initially successful surgical and antibiotic treatment of complicated appendicitis with postoperative occurrence of hemolytic uremic syndrome (HUS). This complication was due to Shiga toxin-producing ... ...

    Abstract We herein describe an 18-month-old boy who underwent initially successful surgical and antibiotic treatment of complicated appendicitis with postoperative occurrence of hemolytic uremic syndrome (HUS). This complication was due to Shiga toxin-producing Escherichia coli (STEC) found secondarily in rectal swabs but not in the peritoneal cavity. The literature indicates that a causal link may exist between these two entities, and HUS could be considered an iatrogenic complication of appendicitis management due to a multimodal stress effect in non-symptomatic STEC carriers.
    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Comparison of the Learning Curve for Robot-Assisted Laparoscopic Pyeloplasty Between Senior and Junior Surgeons.

    Spampinato, Grazia / Binet, Aurelien / Fourcade, Laurent / Mendoza Sagaon, Mario / Villemagne, Thierry / Braik, Karim / Grosos, Celine / Lardy, Hubert / Ballouhey, Quentin

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2021  Volume 31, Issue 4, Page(s) 478–483

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Female ; General Surgery/education ; Humans ; Infant ; Kidney/surgery ; Kidney Pelvis/surgery ; Laparoscopy/methods ; Learning Curve ; Male ; Operative Time ; Reconstructive Surgical Procedures/methods ; Robotic Surgical Procedures/methods ; Specialties, Surgical ; Surgeons ; Ureter/surgery ; Ureteral Obstruction/surgery ; Urologic Surgical Procedures/methods
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2020.0822
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  10. Article ; Online: Robot-assisted laparoscopic pyeloplasty (RALP) in children with complex pelvi-ureteric junction obstruction (PUJO): results of a multicenter European report.

    Esposito, Ciro / Masieri, Lorenzo / Blanc, Thomas / Musleh, Layla / Ballouhey, Quentin / Fourcade, Laurent / Escolino, Maria

    World journal of urology

    2020  Volume 39, Issue 5, Page(s) 1641–1647

    Abstract: Purpose: This study aimed to report a multi-institutional retrospective case series of outcomes after robot-assisted laparoscopic pyeloplasty (RALP) in pediatric patients with complex pelvi-ureteric junction obstruction (PUJO).: Methods: All patients ...

    Abstract Purpose: This study aimed to report a multi-institutional retrospective case series of outcomes after robot-assisted laparoscopic pyeloplasty (RALP) in pediatric patients with complex pelvi-ureteric junction obstruction (PUJO).
    Methods: All patients undergoing complex RALP over the last 5 years were included. RALP was defined complex in the following cases of PUJO: anatomic variations including ectopic, malrotated, horseshoe, or duplex kidney and recurrent PUJO after failed open pyeloplasty.
    Results: Forty-eight patients underwent complex RALP in four European centers in the study period and included 18 girls and 30 boys with a median age of 8 years (range 5-12). The PUJO was associated with anatomic variations in 35/48 (72.9%), whereas a recurrent PUJO was present in 13/48 (27.1%). A dismembered Anderson-Hynes pyeloplasty was performed in all patients. The median operative time including docking was 178.5 min (range 117-255) and the median anastomotic time was 64.8 min (range 50-76). All patients were discharged on 2nd postoperative day (POD). The median follow-up was 18.2 months (range 14-43). The overall success rate was 95.8% (46/48). Early postoperative complications (< 30th POD) included urinary tract infections (UTIs) and stent-related irritative symptoms in 4/48 (8.3%) [II Clavien], whereas late complications (> 30th POD) included recurrence of PUJO in 2/48 (4.2%), who needed re-operation [IIIb Clavien].
    Conclusions: RALP was safe, feasible, and with good mid-term outcome in complex PUJO. An accurate pre-operative planning, a standardized technique, and an experienced surgical robotic team represented key points to manage successfully such complex cases.
    MeSH term(s) Child ; Child, Preschool ; Europe ; Female ; Humans ; Hydronephrosis/congenital ; Hydronephrosis/surgery ; Kidney Pelvis/surgery ; Laparoscopy ; Male ; Multicystic Dysplastic Kidney/surgery ; Retrospective Studies ; Robotic Surgical Procedures ; Treatment Outcome ; Ureteral Obstruction/surgery ; Urologic Surgical Procedures/methods
    Language English
    Publishing date 2020-06-27
    Publishing country Germany
    Document type Journal Article ; Multicenter Study
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-020-03331-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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