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  1. Book: SURGERY OF THE ANUS, RECTUM AND COLON. BY J. C. GOLIGHER, WITH THE COLLABORATION OF H. L. DUTHIE AND H. H. NIXON

    Goligher, John C.

    1980  

    Title variant SURGERY OF THE ANUS, RECTUM AND COLON
    Keywords ANUS / SURGERY ; COLON / SURGERY ; RECTUM / SURGERY ; Colonchirurgie ; Mastdarmchirurgie ; Anorektale Krankheit ; Chirurgie
    Subject Rektumchirurgie ; Kolonchirurgie ; Surgery ; Anorectale Krankheit
    Size VII, 968P, V LEAVES G PLATES
    Edition 4TH ED
    Publisher BAILLIERE TINDALL
    Publishing place LONDON
    Document type Book
    HBZ-ID HT000144620
    ISBN 0-7020-0750-1 ; 978-0-7020-0750-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1981 A 3208 order for loan Magazin

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  2. Article ; Online: Interpreting posterior probabilities in Bayesian analyses of clinical trials.

    Yarnell, Christopher J / Goligher, Ewan C

    The Lancet. Respiratory medicine

    2023  Volume 12, Issue 3, Page(s) 188–190

    MeSH term(s) Humans ; Bayes Theorem ; Probability ; Clinical Trials as Topic
    Language English
    Publishing date 2023-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(23)00459-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7041: Show issues Location:
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  3. Book: Textbook of British surgery / 3 / ed. by J. C. Goligher

    Souttar, Henry / Goligher, John Cedric

    1956  

    Author's details ed. by Henry Souttar
    Collection Textbook of British surgery
    Language English
    Publisher Heinemann
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013554942
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1971 A 1228 -3- order for loan Magazin

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  4. Book: Textbook of British surgery / 2 / ed. by J. C. Goligher

    Souttar, Henry / Goligher, John Cedric

    1956  

    Author's details ed. by Henry Souttar
    Collection Textbook of British surgery
    Language English
    Publisher Heinemann
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013554936
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1971 A 1228 -2- order for loan Magazin

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  5. Book: SURGERY OF THE ANUS, RECTUM AND COLON. BY J. C. GOLIGHER, WITH THE COLLABORATION OF H. L. DUTHIE AND H. H. NIXON

    Goligher, John C.

    1975  

    Title variant SURGERY OF THE ANUS, RECTUM AND COLON
    Keywords Colonchirurgie ; Mastdarmchirurgie ; Anorektale Krankheit ; Chirurgie
    Subject Kolonchirurgie ; Surgery ; Anorectale Krankheit ; Rektumchirurgie
    Size VIII, 1164 S. : ZAHLR. ILL. U. GRAPH. DARST. (Z.T. FARB.)
    Edition 3. Ed.
    Publisher BAILLIERE TINDALL
    Publishing place LONDON
    Document type Book
    HBZ-ID HT002806230
    ISBN 0-7020-0750-1 ; 978-0-7020-0750-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1976 A 115 order for loan Magazin

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  6. Article ; Online: Monitoring Respiratory Effort and Lung-distending Pressure Noninvasively during Mechanical Ventilation: Ready for Prime Time.

    Dianti, Jose / Goligher, Ewan C

    Anesthesiology

    2023  Volume 138, Issue 3, Page(s) 235–237

    MeSH term(s) Respiration, Artificial ; Positive-Pressure Respiration ; Lung
    Language English
    Publishing date 2023-02-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.133: Show issues Location:
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    Zs.MO 199: Show issues

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  7. Article ; Online: Reply to Fernández.

    Dianti, Jose / Morris, Idunn S / Goligher, Ewan C

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 1, Page(s) 111–112

    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202304-0770LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Measuring Diaphragm Thickness and Function Using Point-of-Care Ultrasound.

    Bellissimo, Catherine A / Morris, Idunn S / Wong, Jenna / Goligher, Ewan C

    Journal of visualized experiments : JoVE

    2023  , Issue 201

    Abstract: The diaphragm is the main component of the respiratory muscle pump. Diaphragm dysfunction can cause dyspnea and exercise intolerance, and predisposes affected individuals to respiratory failure. In mechanically ventilated patients, the diaphragm is ... ...

    Abstract The diaphragm is the main component of the respiratory muscle pump. Diaphragm dysfunction can cause dyspnea and exercise intolerance, and predisposes affected individuals to respiratory failure. In mechanically ventilated patients, the diaphragm is susceptible to atrophy and dysfunction through disuse and other mechanisms. This contributes to failure to wean and poor long-term clinical outcomes. Point-of-care ultrasound provides a valid and reproducible method for evaluating diaphragm thickness and contractile activity (thickening fraction during inspiration) that can be readily employed by clinicians and researchers alike. This article presents best practices for measuring diaphragm thickness and quantifying diaphragm thickening during tidal breathing or maximal inspiration. Once mastered, this technique can be used to diagnose and prognosticate diaphragm dysfunction, and guide and monitor response to treatment over time in both healthy individuals and acute or chronically ill patients.
    MeSH term(s) Humans ; Diaphragm/diagnostic imaging ; Point-of-Care Systems ; Thorax ; Respiratory Muscles ; Point-of-Care Testing
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/65431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Lung- and diaphragm-protective strategies in acute respiratory failure: an in silico trial.

    Ratano, Damian / Zhang, Binghao / Dianti, Jose / Georgopoulos, Dimitrios / Brochard, Laurent J / Chan, Timothy C Y / Goligher, Ewan C

    Intensive care medicine experimental

    2024  Volume 12, Issue 1, Page(s) 20

    Abstract: Background: Lung- and diaphragm-protective (LDP) ventilation may prevent diaphragm atrophy and patient self-inflicted lung injury in acute respiratory failure, but feasibility is uncertain. The objectives of this study were to estimate the proportion of ...

    Abstract Background: Lung- and diaphragm-protective (LDP) ventilation may prevent diaphragm atrophy and patient self-inflicted lung injury in acute respiratory failure, but feasibility is uncertain. The objectives of this study were to estimate the proportion of patients achieving LDP targets in different modes of ventilation, and to identify predictors of need for extracorporeal carbon dioxide removal (ECCO
    Methods: An in silico clinical trial was conducted using a previously published mathematical model of patient-ventilator interaction in a simulated patient population (n = 5000) with clinically relevant physiological characteristics. Ventilation and sedation were titrated according to a pre-defined algorithm in pressure support ventilation (PSV) and proportional assist ventilation (PAV+) modes, with or without adjunctive ECCO
    Results: After titration, the proportion of patients achieving targets was lower in PAV+ vs. PSV (37% vs. 43%, odds ratio 0.78, 95% CI 0.73-0.85). Adjunctive ECCO
    Conclusions: In this in silico trial, many patients required ECCO
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2740385-3
    ISSN 2197-425X
    ISSN 2197-425X
    DOI 10.1186/s40635-024-00606-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dyssynchronous diaphragm contractions impair diaphragm function in mechanically ventilated patients.

    Coiffard, Benjamin / Dianti, Jose / Telias, Irene / Brochard, Laurent J / Slutsky, Arthur S / Beck, Jennifer / Sinderby, Christer / Ferguson, Niall D / Goligher, Ewan C

    Critical care (London, England)

    2024  Volume 28, Issue 1, Page(s) 107

    Abstract: Background: Pre-clinical studies suggest that dyssynchronous diaphragm contractions during mechanical ventilation may cause acute diaphragm dysfunction. We aimed to describe the variability in diaphragm contractile loading conditions during mechanical ... ...

    Abstract Background: Pre-clinical studies suggest that dyssynchronous diaphragm contractions during mechanical ventilation may cause acute diaphragm dysfunction. We aimed to describe the variability in diaphragm contractile loading conditions during mechanical ventilation and to establish whether dyssynchronous diaphragm contractions are associated with the development of impaired diaphragm dysfunction.
    Methods: In patients receiving invasive mechanical ventilation for pneumonia, septic shock, acute respiratory distress syndrome, or acute brain injury, airway flow and pressure and diaphragm electrical activity (Edi) were recorded hourly around the clock for up to 7 days. Dyssynchronous post-inspiratory diaphragm loading was defined based on the duration of neural inspiration after expiratory cycling of the ventilator. Diaphragm function was assessed on a daily basis by neuromuscular coupling (NMC, the ratio of transdiaphragmatic pressure to diaphragm electrical activity).
    Results: A total of 4508 hourly recordings were collected in 45 patients. Edi was low or absent (≤ 5 µV) in 51% of study hours (median 71 h per patient, interquartile range 39-101 h). Dyssynchronous post-inspiratory loading was present in 13% of study hours (median 7 h per patient, interquartile range 2-22 h). The probability of dyssynchronous post-inspiratory loading was increased with reverse triggering (odds ratio 15, 95% CI 8-35) and premature cycling (odds ratio 8, 95% CI 6-10). The duration and magnitude of dyssynchronous post-inspiratory loading were associated with a progressive decline in diaphragm NMC (p < 0.01 for interaction with time).
    Conclusions: Dyssynchronous diaphragm contractions may impair diaphragm function during mechanical ventilation.
    Trial registration: MYOTRAUMA, ClinicalTrials.gov NCT03108118. Registered 04 April 2017 (retrospectively registered).
    MeSH term(s) Humans ; Respiration, Artificial/adverse effects ; Diaphragm ; Ventilators, Mechanical ; Respiratory Distress Syndrome ; Thorax
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-024-04894-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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