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Article ; Online: Safe elective surgery: addressing the need.

Kader, Deiary F / Oussedik, Sam / Kader, Nardeen / Haddad, Fares S

2021 Volume 103-B, Issue 4, Page(s) 597–599

MeSH term(s)	COVID-19/epidemiology ; Elective Surgical Procedures ; Health Services Needs and Demand ; Humans ; Infection Control ; Orthopedic Procedures ; Pandemics ; United Kingdom ; Waiting Lists
Language	English
Publishing date	2021-04-01
Publishing country	England
Document type	Editorial
ZDB-ID	2697156-2
ISSN	2049-4408 ; 2049-4394
ISSN (online)	2049-4408
ISSN	2049-4394
DOI	10.1302/0301-620X.103B4.BJJ-2021-0317
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Article ; Online: Home-based rehabilitation following anterior cruciate ligament reconstruction in the Kurdistan region of Iraq: epidemiology and outcomes.

Kader, Nardeen / Jones, Samantha / Serdar, Ziyad / Banaszkiewicz, Paul / Kader, Deiary

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

2022 Volume 33, Issue 3, Page(s) 481–488

Abstract: Purpose: This study, set in in the Kurdistan region of Iraq, describes the epidemiology and outcomes of anterior cruciate ligament reconstruction (ACLR) followed by home-based rehabilitation alone.: Methods: A cohort observational study of patients ... ...

Abstract	Purpose: This study, set in in the Kurdistan region of Iraq, describes the epidemiology and outcomes of anterior cruciate ligament reconstruction (ACLR) followed by home-based rehabilitation alone. Methods: A cohort observational study of patients aged ≥ 16 years with an ACL rupture who underwent an ACLR under a single surgeon. Followed by a home-based rehabilitation programme of appropriate simplicity for completion in the home setting; consisting of stretching, range of motion and strengthening exercises. Demographics, mechanism of injury, operative findings, and outcome data (Lysholm, Tegner Activity Scale (TAS), and revision rates) were collected from 2016 to 2021. Data were analysed using descriptive statistics. Results: The cohort consisted of 545 patients (547 knees), 99.6% were male with a mean age of 27.8 years (SD 6.18 years). The mean time from diagnosis to surgery was 40.6 months (SD 40.3). Despite data attrition Lysholm scores improved over the 15-month follow-up period, matched data showed the most improvement occurred within the first 2 months post-operatively. Post-operative TAS results showed an improvement in level of function, but did not reach pre-injury levels by final follow-up. At final follow-up, six (1.1%) patients required an ACLR revision. Conclusion: Patients who completed a home-based rehabilitation programme in Kurdistan had low revision rates and improved Lysholm scores 15 months post-operatively. To optimise resources, further research should investigate the efficacy of home-based rehabilitation for trauma and elective surgery in low- to middle-income countries and the developed world.
MeSH term(s)	Humans ; Male ; Adult ; Female ; Anterior Cruciate Ligament Injuries/epidemiology ; Anterior Cruciate Ligament Injuries/surgery ; Anterior Cruciate Ligament Injuries/diagnosis ; Iraq/epidemiology ; Cohort Studies ; Anterior Cruciate Ligament Reconstruction/methods ; Lysholm Knee Score ; Treatment Outcome ; Knee Joint/surgery
Language	English
Publishing date	2022-11-29
Publishing country	France
Document type	Observational Study ; Journal Article
ZDB-ID	1231084-0
ISSN	1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
ISSN (online)	1432-1068
ISSN	1633-8065 ; 0948-4817 ; 0940-3264
DOI	10.1007/s00590-022-03431-8
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Zs.A 3479: Show issues

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Article ; Online: Cell-based therapies for the treatment of sports injuries of the upper limb.

Baryeh, Kwaku / Asopa, Vipin / Kader, Nardeen / Caplan, Nick / Maffulli, Nicola / Kader, Deiary

Expert opinion on biological therapy

2021 Volume 21, Issue 12, Page(s) 1561–1574

Abstract: ... ...

Abstract	Introduction
MeSH term(s)	Athletic Injuries/therapy ; Humans ; Rotator Cuff ; Sports ; Tennis Elbow ; Upper Extremity
Language	English
Publishing date	2021-05-31
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2052501-1
ISSN	1744-7682 ; 1471-2598
ISSN (online)	1744-7682
ISSN	1471-2598
DOI	10.1080/14712598.2021.1928630
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Article ; Online: Platelet-rich plasma versus steroids injections for greater trochanter pain syndrome: a systematic review and meta-analysis.

Migliorini, Filippo / Kader, Nardeen / Eschweiler, Jörg / Tingart, Markus / Maffulli, Nicola

British medical bulletin

2021 Volume 139, Issue 1, Page(s) 86–99

Abstract: Introduction: Greater trochanter pain syndrome (GTPS) is characterized by a persistent and debilitating pain around the greater trochanter. GTPS can be caused by a combination of gluteus medius or minimus tendinopathy, snapping hip or trochanteric ... ...

Abstract	Introduction: Greater trochanter pain syndrome (GTPS) is characterized by a persistent and debilitating pain around the greater trochanter. GTPS can be caused by a combination of gluteus medius or minimus tendinopathy, snapping hip or trochanteric bursitis. Source of data: Recent published literatures identified from PubMed, EMBASE, Google Scholar, Scopus. Areas of agreement: Platelet rich plasma (PRP) and corticosteroids (CCS) injections are useful options to manage symptoms of GTPS. Areas of controversy: Whether PRP leads to superior outcomes compared to CCS injections is unclear. Growing points: A systematic review and meta-analysis comparing PRP versus CCS in the management of GTPS was conducted. Areas timely for developing research: PRP injections are more effective than CCS at approximately 2 years follow-up.
MeSH term(s)	Bursitis/drug therapy ; Femur ; Humans ; Pain ; Platelet-Rich Plasma ; Steroids ; Syndrome ; Tendinopathy/drug therapy ; Treatment Outcome
Chemical Substances	Steroids
Language	English
Publishing date	2021-08-26
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	213294-1
ISSN	1471-8391 ; 0007-1420
ISSN (online)	1471-8391
ISSN	0007-1420
DOI	10.1093/bmb/ldab018
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Article ; Online: Cell-based therapy in soft tissue sports injuries of the knee: a systematic review.

Kader, Nardeen / Asopa, Vipin / Baryeh, Kwaku / Sochart, David / Maffulli, Nicola / Kader, Deiary

Expert opinion on biological therapy

2021 Volume 21, Issue 8, Page(s) 1035–1047

Abstract: Introduction: An ever-increasing number of clinics are offering purportedly 'regenerative' stem-cell treatments, although cell-based therapies may not primarily act as stem cells and have shown the ability to regenerate end-target tissues in some ... ...

Abstract	Introduction: An ever-increasing number of clinics are offering purportedly 'regenerative' stem-cell treatments, although cell-based therapies may not primarily act as stem cells and have shown the ability to regenerate end-target tissues in some clinical studies only. We aim to systematically review the evidence for their use in soft-tissue sports injuries of the knee. Areas covered: A search for articles pertaining to the use of preparations of, or containing, mesenchymal stem cells (MSCs) in human subjects in sports knee injuries yielded 14 relevant results for inclusion after screening: 7 used cultured MSCs, 5 bone marrow concentrate (BMC), and the remaining 2 evaluated stromal vascular fraction (SVF) and tenocyte-like-cells. Most studies were level 3 or lower (n = 9). Expert opinion: There is insufficient high-quality evidence for the use of cell-based therapies that demonstrates either ligamentous or tendinous healing, meniscal volume restoration, or post-traumatic osteoarthritis amelioration/regression. Methods of cell harvesting, preparation, and application are highly heterogenous. Efforts should be directed toward standardization of protocols and their reporting, starting with more basic scientific investigations of MSCs and their niche, as well as rigorous, large clinical RCTs adhering to the reporting principles set out by recent expert consensus.
MeSH term(s)	Athletic Injuries/therapy ; Cell- and Tissue-Based Therapy ; Humans ; Knee Joint ; Sports ; Stromal Vascular Fraction
Language	English
Publishing date	2021-01-19
Publishing country	England
Document type	Journal Article ; Systematic Review
ZDB-ID	2052501-1
ISSN	1744-7682 ; 1471-2598
ISSN (online)	1744-7682
ISSN	1471-2598
DOI	10.1080/14712598.2021.1872538
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Article: Evaluating Accuracy of Plain Magnetic Resonance Imaging or Arthrogram versus Wrist Arthroscopy in the Diagnosis of Scapholunate Interosseous Ligament Injury.

Kader, Nardeen / Arshad, Mohammed Shoaib / Chajed, Pawan K / Makki, Daoud / Naikoti, Kiran / Temperley, David / Murali, S Raj

Journal of hand and microsurgery

2020 Volume 14, Issue 4, Page(s) 298–303

Abstract: ... ...

Abstract	Introduction
Language	English
Publishing date	2020-12-10
Publishing country	United States
Document type	Journal Article
ISSN	0974-3227
ISSN	0974-3227
DOI	10.1055/s-0040-1719231
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Article ; Online: A woman with hip pain and teeth in the pelvis.

Malik, Adnan Ather / Yosief, Lydia Salem / Mahdi, Dana / Butt, Umar / Luckiewicz, Andrzej / Malik, Amman / Cassidy, Aaron / Malik, Amina / Kader, Nardeen / Merchant, Fraser / Ali, M Adam

Journal of the American College of Emergency Physicians open

2021 Volume 2, Issue 4, Page(s) e12523

Language	English
Publishing date	2021-08-05
Publishing country	United States
Document type	Journal Article
ISSN	2688-1152
ISSN (online)	2688-1152
DOI	10.1002/emp2.12523
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Article ; Online: The theoretical mortality risk of an asymptomatic patient with a negative SARS-CoV-2 test developing COVID-19 following elective orthopaedic surgery.

Kader, Nardeen / Clement, Nick D / Patel, Vipul R / Caplan, Nick / Banaszkiewicz, Paul / Kader, Deiary

The bone & joint journal

2020 Volume 102-B, Issue 9, Page(s) 1256–1260

Abstract: Aims: The risk to patients and healthcare workers of resuming elective orthopaedic surgery following the peak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been difficult to quantify. This has prompted governing bodies ...

Abstract	Aims: The risk to patients and healthcare workers of resuming elective orthopaedic surgery following the peak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been difficult to quantify. This has prompted governing bodies to adopt a cautious approach that may be impractical and financially unsustainable. The lack of evidence has made it impossible for surgeons to give patients an informed perspective of the consequences of elective surgery in the presence of SARS-CoV-2. This study aims to determine, for the UK population, the probability of a patient being admitted with an undetected SARS-CoV-2 infection and their resulting risk of death; taking into consideration the current disease prevalence, reverse transcription-polymerase chain reaction (RT-PCR) testing, and preassessment pathway. Methods: The probability of SARS-CoV-2 infection with a false negative test was calculated using a lower-end RT-PCR sensitivity of 71%, specificity of 95%, and the UK disease prevalence of 0.24% reported in May 2020. Subsequently, a case fatality rate of 20.5% was applied as a worst-case scenario. Results: The probability of SARS-CoV-2 infection with a false negative preoperative test was 0.07% (around 1 in 1,400). The risk of a patient with an undetected infection being admitted for surgery and subsequently dying from the coronavirus disease 2019 (COVID-19) is estimated at approximately 1 in 7,000. However, if an estimate of the current global infection fatality rate (1.04%) is applied, the risk of death would be around 1 in 140,000, at most. This calculation does not take into account the risk of nosocomial infection. Conversely, it does not factor in that patients will also be clinically assessed and asked to self-isolate prior to surgery. Conclusion: Our estimation suggests that the risk of patients being inadvertently admitted with an undetected SARS-CoV-2 infection for elective orthopaedic surgery is relatively low. Accordingly, the risk of death following elective orthopaedic surgery is low, even when applying the worst-case fatality rate. Cite this article:
MeSH term(s)	Asymptomatic Diseases ; Bayes Theorem ; COVID-19 ; COVID-19 Testing ; Cause of Death ; Clinical Laboratory Techniques ; Cohort Studies ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Elective Surgical Procedures/adverse effects ; Elective Surgical Procedures/mortality ; False Negative Reactions ; Female ; Humans ; Incidence ; Male ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Postoperative Complications/mortality ; Postoperative Complications/physiopathology ; Risk Assessment ; Survival Rate ; Treatment Outcome ; United Kingdom
Keywords	covid19
Language	English
Publishing date	2020-07-06
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2697156-2
ISSN	2049-4408 ; 2049-4394
ISSN (online)	2049-4408
ISSN	2049-4394
DOI	10.1302/0301-620X.102B9.BJJ-2020-1147.R1
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Article ; Online: The rate of COVID-19 and associated mortality after elective hip and knee arthroplasty prior to cessation of elective services in UK.

Clement, Nicholas D / Hall, Andrew J / Kader, Nardeen / Ollivere, Benjamin / Oussedik, Sam / Kader, Deiary F / Deehan, David J / Duckworth, Andrew D

The bone & joint journal

2021 Volume 103-B, Issue 4, Page(s) 681–688

Abstract: Aims: The primary aim was to assess the rate of postoperative COVID-19 following hip and knee arthroplasty performed in March 2020 in the UK. The secondary aims were to assess whether there were clinical factors associated with COVID-19 status, the ... ...

Abstract	Aims: The primary aim was to assess the rate of postoperative COVID-19 following hip and knee arthroplasty performed in March 2020 in the UK. The secondary aims were to assess whether there were clinical factors associated with COVID-19 status, the mortality rate of patients with COVID-19, and the rate of potential COVID-19 in patients not presenting to healthcare services. Methods: A multicentre retrospective study was conducted of patients undergoing hip or knee arthroplasty during the first wave of the COVID-19 pandemic (1 March 2020 to 31 March 2020) with a minimum of 60 days follow-up. Patient demographics, American Society of Anesthesiologists grade, procedure type, primary or revision, length of stay (LOS), COVID-19 test status, and postoperative mortality were recorded. A subgroup of patients (n = 211) who had not presented to healthcare services after discharge were contacted and questioned as to whether they had symptoms of COVID-19. Results: Five (0.5%) of 1,073 patients who underwent hip or knee arthroplasty tested positive for SARS-CoV-2 postoperatively. When adjusting for confounding factors, increasing LOS (p = 0.022) was the only significant factor associated with developing COVID-19 following surgery and a stay greater than three days was a reliable predictor with an area under the curve of 81% (p = 0.018). There were three (0.3%) deaths in the study cohort and the overall mortality rate attributable to COVID-19 was 0.09% (n = 1/1,073), with one (20%) of the five patients with COVID-19 dying postoperatively. Of the 211 patients contacted, two had symptoms within two to 14 days postoperatively with a positive predictive value of 31% and it was therefore estimated that one patient may have had undiagnosed COVID-19. Conclusion: The rate of postoperative COVID-19 was 0.5% and may have been as high as 1% when accounting for those patients not presenting to healthcare services, which was similar to the estimated population prevalence during the study period. The overall mortality rate secondary to COVID-19 was low (0.09%), however the mortality rate for those patients developing COVID-19 was 20%. Cite this article:
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip ; Arthroplasty, Replacement, Knee ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/etiology ; COVID-19/prevention & control ; COVID-19 Testing ; Clinical Audit ; Elective Surgical Procedures ; Female ; Follow-Up Studies ; Health Services Accessibility ; Humans ; Male ; Middle Aged ; Postoperative Complications/diagnosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Survival Analysis ; United Kingdom/epidemiology
Language	English
Publishing date	2021-02-16
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	2697156-2
ISSN	2049-4408 ; 2049-4394
ISSN (online)	2049-4408
ISSN	2049-4394
DOI	10.1302/0301-620X.103B.BJJ-2020-1776.R1
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Article: The X-Pulley Technique for Subpectoral Long Head of the Biceps Tenodesis Using All-Suture Anchors.

Consigliere, Paolo / Salamat, Shadi / Kader, Nardeen / Imam, Mohamed / Gowda, Abhilash / Narvani, A Ali

Arthroscopy techniques

2019 Volume 8, Issue 2, Page(s) e189–e197

Abstract: Subpectoral long head of the biceps tenodesis is gaining popularity as a technique for treating patients with various pathologies of the tendon or its anchor to the superior labrum. It has the added advantage of addressing bicipital groove pathologies. ... ...

Abstract	Subpectoral long head of the biceps tenodesis is gaining popularity as a technique for treating patients with various pathologies of the tendon or its anchor to the superior labrum. It has the added advantage of addressing bicipital groove pathologies. Various techniques for performing it have been described, but none is without problems. We present a modification of the previously described techniques that involves 2 all-suture anchors and offers the added advantage of a reduced risk of fracture without sacrificing the biomechanical strength of the construct. We also believe that it may potentiate healing by providing an adequate surface contact area between the tendon and bone with a minimal risk of damage to the tendon and neurovascular structures.
Language	English
Publishing date	2019-01-28
Publishing country	Netherlands
Document type	Journal Article
ISSN	2212-6287
ISSN	2212-6287
DOI	10.1016/j.eats.2018.10.012
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