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Book ; Thesis: Smith-Magenis-Syndrom (Deletion 17p11.2) und Monosomie 1p36, zwei Mikrodeletionssyndrome mit ähnlichem klinischen Phänotyp

Versuch einer Diagnosestellung bei Patienten mit einer Entwicklungsverzögerung unklarer Ätiologie

2005

Author's details	vorgelegt von Christian Johannes Ulrich Godt
Language	German
Size	50 S. : Ill., graph. Darst.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Kiel, Univ., Diss., 2005
HBZ-ID	HT014519867
Database	Catalogue ZB MED Medicine, Health

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2004 D 1817	order for loan	Magazin

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Article ; Online: Do we really need the arterial phase on CT in pelvic trauma patients?

Godt, Johannes Clemens / Eken, Torsten / Schulz, Anselm / Øye, Kjetil / Hagen, Thijs / Dormagen, Johann Baptist

Emergency radiology

2020 Volume 28, Issue 1, Page(s) 37–46

Abstract: Purpose: To evaluate whether an arterial phase scan improves the diagnostic performance of computed tomography to identify pelvic trauma patients who received angiographic intervention on demand of the trauma surgeon.: Methods: This retrospective ... ...

Abstract	Purpose: To evaluate whether an arterial phase scan improves the diagnostic performance of computed tomography to identify pelvic trauma patients who received angiographic intervention on demand of the trauma surgeon. Methods: This retrospective single-center study was performed at an academic Scandinavian trauma center with approximately 2000 trauma admissions annually. Pelvic trauma patients with arterial and portal venous phase CT from 2009 to 2015 were included. The patients were identified from the institutional trauma registry. Images were interpreted by two radiologists with more than 10 years of trauma radiology experience. Positive findings for extravasation on portal venous phase alone or on both arterial and portal venous phase were compared, with angiographic intervention as clinical outcome. Results: One hundred fifty-seven patients (54 females, 103 males) with a median age of 45 years were enrolled. Sixteen patients received angiographic intervention. Positive CT findings on portal venous phase only had a sensitivity and specificity of 62% and 86%, vs. 56% and 93% for simultaneous findings on arterial and portal venous phase. Specificity was significantly higher for positive findings in both phases compared with portal venous phase only. Applying a threshold > 0.9 cm of extravasation diameter to portal venous phase only resulted in sensitivity and specificity identical to those of both phases. Conclusion: Arterial phase scan in addition to portal venous phase scan did not improve patient selection for angiography. Portal venous phase extravasation size alone may be used as an imaging-based biomarker of the need for angiographic intervention.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Computed Tomography Angiography/methods ; Contrast Media ; Female ; Humans ; Injury Severity Score ; Iopamidol/analogs & derivatives ; Male ; Middle Aged ; Pelvic Bones/injuries ; Radiographic Image Interpretation, Computer-Assisted ; Retrospective Studies ; Sensitivity and Specificity ; Trauma Centers ; Wounds, Nonpenetrating/diagnostic imaging
Chemical Substances	Contrast Media ; iomeprol (17E17JBP8L) ; Iopamidol (JR13W81H44)
Language	English
Publishing date	2020-07-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	1425144-9
ISSN	1438-1435 ; 1070-3004
ISSN (online)	1438-1435
ISSN	1070-3004
DOI	10.1007/s10140-020-01820-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Iterative reconstruction improves image quality and reduces radiation dose in trauma protocols; A human cadaver study.

Godt, Johannes Clemens / Johansen, Cathrine K / Martinsen, Anne Catrine T / Schulz, Anselm / Brøgger, Helga M / Jensen, Kristin / Stray-Pedersen, Arne / Dormagen, Johann Baptist

Acta radiologica open

2021 Volume 10, Issue 10, Page(s) 20584601211055389

Abstract: Background: Radiation-related cancer risk is an object of concern in CT of trauma patients, as these represent a young population. Different radiation reducing methods, including iterative reconstruction (IR), and spilt bolus techniques have been ... ...

Abstract	Background: Radiation-related cancer risk is an object of concern in CT of trauma patients, as these represent a young population. Different radiation reducing methods, including iterative reconstruction (IR), and spilt bolus techniques have been introduced in the recent years in different large scale trauma centers. Purpose: To compare image quality in human cadaver exposed to thoracoabdominal computed tomography using IR and standard filtered back-projection (FBP) at different dose levels. Material and methods: Ten cadavers were scanned at full dose and a dose reduction in CTDIvol of 5 mGy (low dose 1) and 7.5 mGy (low dose 2) on a Siemens Definition Flash 128-slice computed tomography scanner. Low dose images were reconstructed with FBP and Sinogram affirmed iterative reconstruction (SAFIRE) level 2 and 4. Quantitative image quality was analyzed by comparison of contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). Qualitative image quality was evaluated by use of visual grading regression (VGR) by four radiologists. Results: Readers preferred SAFIRE reconstructed images over FBP at a dose reduction of 40% (low dose 1) and 56% (low dose 2), with significant difference in overall impression of image quality. CNR and SNR showed significant improvement for images reconstructed with SAFIRE 2 and 4 compared to FBP at both low dose levels. Conclusions: Iterative image reconstruction, SAFIRE 2 and 4, resulted in equal or improved image quality at a dose reduction of up to 56% compared to full dose FBP and may be used a strong radiation reduction tool in the young trauma population.
Language	English
Publishing date	2021-11-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2818429-4
ISSN	2058-4601
ISSN	2058-4601
DOI	10.1177/20584601211055389
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Article: Improved image quality in abdominal computed tomography reconstructed with a novel Deep Learning Image Reconstruction technique - initial clinical experience.

Njølstad, Tormund / Schulz, Anselm / Godt, Johannes C / Brøgger, Helga M / Johansen, Cathrine K / Andersen, Hilde K / Martinsen, Anne Catrine T

Acta radiologica open

2021 Volume 10, Issue 4, Page(s) 20584601211008391

Abstract: Background: A novel Deep Learning Image Reconstruction (DLIR) technique for computed tomography has recently received clinical approval.: Purpose: To assess image quality in abdominal computed tomography reconstructed with DLIR, and compare with ... ...

Abstract	Background: A novel Deep Learning Image Reconstruction (DLIR) technique for computed tomography has recently received clinical approval. Purpose: To assess image quality in abdominal computed tomography reconstructed with DLIR, and compare with standardly applied iterative reconstruction. Material and methods: Ten abdominal computed tomography scans were reconstructed with iterative reconstruction and DLIR of medium and high strength, with 0.625 mm and 2.5 mm slice thickness. Image quality was assessed using eight visual grading criteria in a side-by-side comparative setting. All series were presented twice to evaluate intraobserver agreement. Reader scores were compared using univariate logistic regression. Image noise and contrast-to-noise ratio were calculated for quantitative analyses. Results: For 2.5 mm slice thickness, DLIR images were more frequently perceived as equal or better than iterative reconstruction across all visual grading criteria (for both DLIR of medium and high strength, p < 0.001). Correspondingly, DLIR images were more frequently perceived as better (as opposed to equal or in favor of iterative reconstruction) for visual reproduction of liver parenchyma, intrahepatic vascular structures as well as overall impression of image noise and texture (p < 0.001). This improved image quality was also observed for 0.625 mm slice images reconstructed with DLIR of high strength when directly comparing to traditional iterative reconstruction in 2.5 mm slices. Image noise was significantly lower and contrast-to-noise ratio measurements significantly higher for images reconstructed with DLIR compared to iterative reconstruction (p < 0.01). Conclusions: Abdominal computed tomography images reconstructed using a DLIR technique shows improved image quality when compared to standardly applied iterative reconstruction across a variety of clinical image quality criteria.
Language	English
Publishing date	2021-04-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2818429-4
ISSN	2058-4601
ISSN	2058-4601
DOI	10.1177/20584601211008391
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Jahresbericht 1975

Godt, Karl Johannes

(GSF-Bericht : S ; 400)

1975

Institution	Gesellschaft für Strahlen- und Umweltforschung Institut für Radiohydrometrie
Author's details	Gesellschaft für Strahlen- und Umweltforschung, München ; Institut für Radiohydrometrie. Zsgest. von K.-J. Godt
Series title	GSF-Bericht : S ; 400 GSF-Bericht / Gesellschaft für Strahlen- und Umweltforschung GSF-Bericht ; S
Collection	GSF-Bericht / Gesellschaft für Strahlen- und Umweltforschung GSF-Bericht ; S
Language	German
Publishing place	Neuherberg bei München
Publishing country	Germany
Document type	Book
HBZ-ID	HT013173086
Database	Catalogue ZB MED Medicine, Health

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Se 404 -S-400-	verfügbar in Königswinter	Königswinter

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Article ; Online: Triple-split-bolus versus single-bolus CT in abdominal trauma patients: a comparative study.

Godt, Johannes Clemens / Eken, Torsten / Schulz, Anselm / Johansen, Cathrine K / Aarsnes, Anette / Dormagen, Johann Baptist

Acta radiologica (Stockholm, Sweden : 1987)

2018 Volume 59, Issue 9, Page(s) 1038–1044

Abstract: Background Split-bolus computed tomography (CT) is a recent development in trauma imaging. Instead of multiple scans in different contrast phases after a single contrast bolus, split-bolus protocols consist of one single scan of the thorax and abdomen ... ...

Abstract	Background Split-bolus computed tomography (CT) is a recent development in trauma imaging. Instead of multiple scans in different contrast phases after a single contrast bolus, split-bolus protocols consist of one single scan of the thorax and abdomen after two or three contrast injections at different points of time. Purpose To evaluate and compare image quality and injury findings of a new triple-split-bolus CT (TS-CT) protocol of thorax and abdomen with those of a portal venous phase CT (PV-CT) in the same patient group. Material and Methods Trauma patients in 2009-2012 who underwent both the TS-CT initially and a PV-CT during the next six weeks were included. The TS-CT examination was performed as one CT run after application of three contrast boluses (total 175 mL) to enhance renal pelvis and urinary tract, the abdominal organs, and the large arterial vessels. The PV-CT had a fixed delay of 85 s. We measured attenuation in Hounsfield units (HU), evaluated possible organ injury and assessed image quality on a 5-point scale. Results Thirty-five patients were included. Attenuation measurements of major abdominal vessels, organs, and renal pelvis were significantly higher with the TS-CT protocol. Performance in organ injury diagnosis and image quality was equal in both protocols. Conclusion The overall performance of the TS-CT protocol is similar to the standard PV-CT. Excellent visualization of the arterial tree and the collecting system may eliminate the need for separate scans.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Contrast Media/administration & dosage ; Female ; Humans ; Iopamidol/administration & dosage ; Iopamidol/analogs & derivatives ; Male ; Middle Aged ; Radiography, Abdominal/methods ; Retrospective Studies ; Tomography, X-Ray Computed/methods ; Wounds and Injuries/diagnostic imaging
Chemical Substances	Contrast Media ; iomeprol (17E17JBP8L) ; Iopamidol (JR13W81H44)
Language	English
Publishing date	2018-09
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/0284185117752522
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Ue I Zs.105: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 204: Show issues

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Article ; Online: Når omentet snur seg.

Godt, Johannes / Kubon, Christer / Hirschberg, Tom

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

2013 Volume 133, Issue 8, Page(s) 854

Title translation	Omental torsion.
MeSH term(s)	Abdominal Pain/etiology ; Adult ; Female ; Humans ; Omentum/diagnostic imaging ; Omentum/pathology ; Omentum/surgery ; Peritoneal Diseases/complications ; Peritoneal Diseases/diagnostic imaging ; Peritoneal Diseases/surgery ; Tomography, X-Ray Computed ; Torsion Abnormality/complications ; Torsion Abnormality/diagnostic imaging ; Torsion Abnormality/surgery
Language	Norwegian
Publishing date	2013-04-23
Publishing country	Norway
Document type	Case Reports ; Journal Article
ZDB-ID	603504-8
ISSN	0807-7096 ; 0029-2001
ISSN (online)	0807-7096
ISSN	0029-2001
DOI	10.4045/tidsskr.12.1301
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Zs.B 422: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 546: Show issues

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Book ; Online ; Thesis: Untersuchungen zur Resorption von Arbeits- und Umweltschadstoffen aus Bodenproben im Modell der isolierten, hämoperfundierten Schweineextremität

Godt, Johannes Jakob Clemens [Verfasser]

2007

Author's details	von Johannes Jakob Clemens Godt
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	German
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Conference proceedings ; Online: Profitiert der Feldhase vom ökologischen Landbau?

Lang, Johannes / Godt, Dr. Jochen

2009

Abstract: European brown hare numbers have dramatically declined in arable land throughout Europe. Loss of food abundance and cover due to mechanisation and intensification of agriculture are suggested to be the main reasons for this decline. Organic farming ... ...

Abstract	European brown hare numbers have dramatically declined in arable land throughout Europe. Loss of food abundance and cover due to mechanisation and intensification of agriculture are suggested to be the main reasons for this decline. Organic farming should sustain higher hare densities because of better habitat quality and higher food abundance. In our study hare densities estimated during spotlight counts increased from eight hares per km² (1998) up to 55 hares (2008) per km² after conversion of the study site from conventional to organic farming. Reasons for this increase in hare density may be higher abundance of year-round forage and cover as shown by preliminary results of radio-tracking data. Organic farming sustains good habitat quality for European hares and enhances their densities. Conservation strategies should therefore promote organic farming as a management tool.
Keywords	Biodiversity and ecosystem services
Language	German
Publishing country	dk
Document type	Conference proceedings ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Respiratory gated PET/CT of the liver: A novel method and its impact on the detection of colorectal liver metastases.

Schulz, Anselm / Godt, Johannes Clemens / Dormagen, Johann Baptist / Holtedahl, Jon Erik / Bogsrud, Trond Velde / Labori, Knut Jørgen / Kløw, Nils-Einar / Bach-Gansmo, Tore

European journal of radiology

2015 Volume 84, Issue 8, Page(s) 1424–1431

Abstract: Purpose: To evaluate the diagnostic performance of a new method for respiratory gated positron emission tomography (rgPET/CT) for colorectal liver metastases (CRLM), secondly, to assess its additional value to standard PET/CT (PET/CT).: Materials and ... ...

Abstract	Purpose: To evaluate the diagnostic performance of a new method for respiratory gated positron emission tomography (rgPET/CT) for colorectal liver metastases (CRLM), secondly, to assess its additional value to standard PET/CT (PET/CT). Materials and methods: Forty-three patients scheduled for resection of suspected CRLM were prospectively included from September 2011 to January 2013. None of the patients had previously undergone treatment for their CRLM. All patients underwent PET/CT and rgPET/CT in the same session. For rgPET/CT an in-house developed electronic circuit was used which displayed a color-coded countdown for the patient. The patients held their breath according to the countdown and only the data from the inspiration breath-hold period was used for image reconstruction. Two independent and blinded readers evaluated both PET/CT and rgPET/CT separately. The reference standard was histopathological confirmation for 73 out of 131 CRLM and follow-up otherwise. Results: Reference standard identified 131 CRLM in 39/43 patients. Nine patients accounted for 25 mucinous CRLM. The overall per-lesion sensitivity for detection of CRLM was for PET/CT 60.0%, for rgPET/CT 63.1%, and for standard+rgPET/CT 67.7%, respectively. Standard+rgPET/CT was overall significantly more sensitive for CRLM compared to PET/CT (p=0.002) and rgPET/CT (p=0.031). The overall positive predictive value (PPV) for detection of CRLM was for PET/CT 97.5%, for rgPET/CT 95.3%, and for standard+rgPET/CT 93.6%, respectively. Conclusion: Combination of PET/CT and rgPET/CT improved the sensitivity significantly for CRLM. However, high patient compliance is mandatory to achieve optimal performance and further improvements are needed to overcome these limitations. The diagnostic performance of the evaluated new method for rgPET/CT was comparable to earlier reported technically more complex and expensive methods.
MeSH term(s)	Aged ; Colorectal Neoplasms/pathology ; Female ; Humans ; Liver/diagnostic imaging ; Liver Neoplasms/diagnosis ; Liver Neoplasms/secondary ; Male ; Multimodal Imaging/methods ; Neoplasms, Second Primary/diagnosis ; Observer Variation ; Positron-Emission Tomography/methods ; Prospective Studies ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2015-08
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2015.05.011
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