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  1. Article ; Online: Purpose in life and cognitive health: a 28-year prospective study.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Terracciano, Antonio

    International psychogeriatrics

    2024  , Page(s) 1–9

    Abstract: Objectives: To examine the prospective association between purpose in life measured at three points across middle and older adulthood and cognitive outcomes assessed 8-28 years later.: Design: Prospective Study.: Setting: Wisconsin Longitudinal ... ...

    Abstract Objectives: To examine the prospective association between purpose in life measured at three points across middle and older adulthood and cognitive outcomes assessed 8-28 years later.
    Design: Prospective Study.
    Setting: Wisconsin Longitudinal Study of Aging (WLS).
    Participants: WLS participants who reported on their purpose in life at Round 4 (1992-1994;
    Measurements: Participants completed the Ryff measure of purpose in life and were administered the telephone interview for cognitive status and measures of verbal fluency, digit ordering, and numeric reasoning.
    Results: Purpose in life measured at age 52 was related to better global cognitive function and verbal fluency but unrelated to dementia at age 80. In contrast, purpose in life at ages 63-70 was associated with lower likelihood of dementia, as well as better global cognitive function and verbal fluency at age 80. The effect sizes were modest (median Beta coefficient = .05; median odds ratio = .85). A slightly steeper decline in purpose in life between ages 52 and 70 was found for individuals with dementia at age 80.
    Conclusions: Purpose in life is associated with healthier cognitive function measured up to 28 years later. Individuals with lower purpose, especially in their 60s or older, and with steeper declines in purpose, are more likely to have dementia at age 80.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1038825-4
    ISSN 1741-203X ; 1041-6102
    ISSN (online) 1741-203X
    ISSN 1041-6102
    DOI 10.1017/S1041610224000383
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  2. Article: Purpose in Life and Risk of Falls: A Meta-Analysis of Cross-Sectional and Prospective Associations.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Canada, Brice / Terracciano, Antonio

    Gerontology & geriatric medicine

    2024  Volume 10, Page(s) 23337214241236039

    Abstract: Background and Aim: ...

    Abstract Background and Aim:
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844974-5
    ISSN 2333-7214 ; 2333-7214
    ISSN (online) 2333-7214
    ISSN 2333-7214
    DOI 10.1177/23337214241236039
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  3. Article ; Online: The benefits of a sense of purpose in life for healthier cognitive aging.

    Sutin, Angelina R / Luchetti, Martina / Terracciano, Antonio

    International psychogeriatrics

    2022  Volume 34, Issue 12, Page(s) 1015–1017

    MeSH term(s) Humans ; Cognitive Aging ; Healthy Aging ; Health Status
    Language English
    Publishing date 2022-09-19
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1038825-4
    ISSN 1741-203X ; 1041-6102
    ISSN (online) 1741-203X
    ISSN 1041-6102
    DOI 10.1017/S1041610222000837
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  4. Article ; Online: Physical, cognitive, and social activities as mediators between personality and cognition: evidence from four prospective samples.

    Stephan, Yannick / Sutin, Angelina R / Luchetti, Martina / Aschwanden, Damaris / Terracciano, Antonio

    Aging & mental health

    2024  , Page(s) 1–10

    Abstract: Objectives: The present study examined how activity engagement mediates the association between personality and cognition.: Methods: Participants were middle-aged and older adults (Age range: 24-93 years; : Results: Random-effect meta-analyses ... ...

    Abstract Objectives: The present study examined how activity engagement mediates the association between personality and cognition.
    Methods: Participants were middle-aged and older adults (Age range: 24-93 years;
    Results: Random-effect meta-analyses indicated that lower neuroticism and higher extraversion, openness, and conscientiousness were prospectively associated with better cognition. Most of these associations were partly mediated by greater engagement in physical and cognitive activities but not social activities. Physical activity accounted for 7% (neuroticism) to 50% (extraversion) and cognitive activity accounted for 14% (neuroticism) to 45% (extraversion) of the association with cognition.
    Conclusion: The present study provides replicable evidence that physical and cognitive activities partly mediate the prospective association between personality traits and cognitive functioning.
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1474804-6
    ISSN 1364-6915 ; 1360-7863
    ISSN (online) 1364-6915
    ISSN 1360-7863
    DOI 10.1080/13607863.2024.2320135
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  5. Article ; Online: Functional Capacity and Difficulties in Activities of Daily Living From a Cross-National Perspective.

    Kekäläinen, Tiia / Luchetti, Martina / Sutin, Angelina / Terracciano, Antonio

    Journal of aging and health

    2022  Volume 35, Issue 5-6, Page(s) 356–369

    Abstract: ... ...

    Abstract Objectives
    MeSH term(s) Humans ; Activities of Daily Living ; Disability Evaluation ; Cognition ; Hand Strength
    Language English
    Publishing date 2022-10-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1045392-1
    ISSN 1552-6887 ; 0898-2643
    ISSN (online) 1552-6887
    ISSN 0898-2643
    DOI 10.1177/08982643221128929
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  6. Article ; Online: Sense of purpose in life and work-life tension: Perceptions of interference and enhancement.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Terracciano, Antonio

    Aging and health research

    2023  Volume 3, Issue 3

    Abstract: This research examines the relation between purpose in life and perceptions of work-life interference (work interferes with personal life and vice versa) and enhancement (work enhances personal life and vice versa) and whether these dimensions mediate ... ...

    Abstract This research examines the relation between purpose in life and perceptions of work-life interference (work interferes with personal life and vice versa) and enhancement (work enhances personal life and vice versa) and whether these dimensions mediate purpose and cognition over 10 years. Employed participants from the Health and Retirement Study (
    Language English
    Publishing date 2023-07-22
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-0321
    ISSN (online) 2667-0321
    DOI 10.1016/j.ahr.2023.100154
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  7. Article ; Online: Purpose in life and slow walking speed: cross-sectional and longitudinal associations.

    Sutin, Angelina R / Cajuste, Sabrina / Stephan, Yannick / Luchetti, Martina / Kekäläinen, Tiia / Terracciano, Antonio

    GeroScience

    2024  Volume 46, Issue 3, Page(s) 3377–3386

    Abstract: The present research examines the association between purpose in life - a component of well-being defined as the feeling that one's life is goal-oriented and has direction - and slow walking speed and the risk of developing slow walking speed over time. ... ...

    Abstract The present research examines the association between purpose in life - a component of well-being defined as the feeling that one's life is goal-oriented and has direction - and slow walking speed and the risk of developing slow walking speed over time. Participants (N = 18,825) were from three established longitudinal studies of older adults. At baseline, participants reported on their purpose in life, and interviewers measured their usual walking speed. Walking speed was measured at annual or biannual follow-up waves up to 16 years later. Random-effects meta-analysis was used to summarize the estimates from the individual studies. Every standard deviation higher in purpose in life (as a continuous measure) was associated with a lower likelihood of cross-sectional slow walking speed at baseline (meta-analytic OR = .80, 95% CI = .77-.83). Among participants who did not have slow walking speed at baseline (n = 8,448), every standard deviation higher purpose in life was associated with a lower likelihood of developing slow walking speed over the up to 16 years of follow-up (meta-analytic HR = .93, 95% CI = .89-.96). Physical activity and disease burden accounted for 25% and 14% of the cross-sectional and longitudinal associations, respectively. The associations were independent of age, sex, race, ethnicity, and education and not moderated by these factors. Higher purpose in life is associated with a lower risk of slow walking speed and a lower risk of developing slow walking speed over time. Purpose in life is a psychological resource that may help to support aspects of physical function, such as walking speed, and may help support better function with age.
    MeSH term(s) Humans ; Aged ; Walking Speed ; Cross-Sectional Studies ; Longitudinal Studies ; Walking ; Exercise
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2886586-8
    ISSN 2509-2723 ; 2509-2715
    ISSN (online) 2509-2723
    ISSN 2509-2715
    DOI 10.1007/s11357-024-01073-8
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  8. Article ; Online: Meaning in life and Parkinson's disease in the UK Biobank.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Terracciano, Antonio

    Clinical parkinsonism & related disorders

    2023  Volume 10, Page(s) 100231

    Abstract: Introduction: Meaning in life is an aspect of eudaimonic well-being associated with lower dementia risk. This research examines whether this protective association extends to Parkinson's disease (PD).: Methods: Participants (: Results: Meaning in ... ...

    Abstract Introduction: Meaning in life is an aspect of eudaimonic well-being associated with lower dementia risk. This research examines whether this protective association extends to Parkinson's disease (PD).
    Methods: Participants (
    Results: Meaning in life was associated with a 50 % lower likelihood of prevalent PD (OR = 0.68, 95 % CI = 0.59-0.78). Over the 5-year follow-up, meaning was associated with a 35 % lower risk of incident PD (HR = 0.74, 95 % CI = 0.65-0.83), an association robust to sociodemographic characteristics, depression, history of seeking mental health care, smoking, physical activity, and genetic risk and not moderated by age, sex, education, deprivation, or genetic risk.
    Conclusions: Meaning in life is associated with lower risk of incident PD, an association independent of other major risk factors and generalizable across sociodemographic groups. Meaning is a promising target of intervention for common neurodegenerative diseases.
    Language English
    Publishing date 2023-12-27
    Publishing country England
    Document type Journal Article
    ISSN 2590-1125
    ISSN (online) 2590-1125
    DOI 10.1016/j.prdoa.2023.100231
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  9. Article: Informant-rated change in personality traits, psychological distress, well-being, and social connection with dementia.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Terracciano, Antonio

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Objectives: Studies of retrospective personality change with dementia consistently find caregivers report large changes in personality (e.g., increases in neuroticism) of their care recipients compared to before dementia. This work seeks to replicate ... ...

    Abstract Objectives: Studies of retrospective personality change with dementia consistently find caregivers report large changes in personality (e.g., increases in neuroticism) of their care recipients compared to before dementia. This work seeks to replicate the established pattern of personality change, extend it to change in psychological distress, well-being, and social connection, and evaluate whether changes vary by stage of dementia.
    Methods: Caregivers of people with dementia (
    Results: There were substantial increases in neuroticism (
    Discussion: In addition to personality, there are large retrospective changes in psychological distress, well-being, and social connection with dementia. These quantitative findings complement clinical observations of the natural history of psychosocial changes in people with dementia, and can inform families, clinicians, and researchers on commonly observed changes and improve interventions to mitigate dementia burden.
    Language English
    Publishing date 2023-08-20
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.18.23294273
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  10. Article ; Online: Informant-rated change in personality traits, psychological distress, well-being, and social connection with dementia.

    Sutin, Angelina R / Luchetti, Martina / Stephan, Yannick / Terracciano, Antonio

    Archives of gerontology and geriatrics

    2023  Volume 115, Page(s) 105218

    Abstract: Objectives: Studies of retrospective personality change with dementia consistently find caregivers report large changes in personality (e.g., increases in neuroticism) of their care recipients compared to before dementia. This work seeks to replicate ... ...

    Abstract Objectives: Studies of retrospective personality change with dementia consistently find caregivers report large changes in personality (e.g., increases in neuroticism) of their care recipients compared to before dementia. This work seeks to replicate the established pattern of personality change, extend it to change in psychological distress, well-being, and social connection, and evaluate whether changes vary by stage of dementia.
    Methods: Caregivers of people with dementia (N = 188) reported on the psychological and social health of their care recipient currently and how they were before they developed dementia. Personality was measured as five factor model traits. Psychological distress was measured as symptoms of depression and anxiety, perceived stress, and pessimism. Psychological well-being was measured as purpose in life, life satisfaction, happiness, self-efficacy, and optimism. Social connection was measured as loneliness, belonging, social support, and social strain.
    Results: There were substantial increases in neuroticism (d = 1.14) and decreases in the other four personality traits (d range=-0.85 to -1.37). There were significant increases in psychological distress (e.g., d = 1.07 for depression) and substantial decreases in well-being (e.g., d=-1.18 for purpose in life) and social connection (e.g., d=-1.12 for belonging). Change was apparent across dementia stage and generally larger in more severe dementia.
    Discussion: In addition to personality, there are large retrospective changes in psychological distress, well-being, and social connection with dementia. These quantitative findings complement clinical observations of the natural history of psychosocial changes in people with dementia, and can inform families, clinicians, and researchers on commonly observed changes and improve interventions to mitigate dementia burden.
    MeSH term(s) Humans ; Retrospective Studies ; Personality ; Dementia/psychology ; Anxiety/psychology ; Psychological Distress ; Caregivers/psychology ; Stress, Psychological/psychology
    Language English
    Publishing date 2023-10-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2023.105218
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