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  1. Book: Controversies in neuro-oncology

    Quiñones-Hinojosa, Alfredo / Raza, Shaan M.

    best evidence medicine for brain tumor surgery

    2014  

    Author's details Alfredo Quiñones-Hinojosa ; Shaan M. Raza
    Keywords Brain Neoplasms / surgery ; Brain Neoplasms / radiotherapy ; Evidence-Based Medicine / methods ; Radiosurgery / methods ; Neurosurgical Procedures
    Language English
    Size XXIII, 495 S. : Ill., graph. Darst.
    Publisher Thieme
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017812345
    ISBN 978-1-60406-755-2 ; 1-60406-755-1 ; 9781604067569 ; 160406756X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 2917 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Introduction. Chordoma: updates and advances.

    Gardner, Paul A / Froelich, Sebastien / Gokaslan, Ziya L / MacDonald, Shannon M / Peris Celda, Maria / Raza, Shaan M / Zenonos, Georgios A

    Neurosurgical focus

    2024  Volume 56, Issue 5, Page(s) E1

    MeSH term(s) Humans ; Chordoma
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Introductory Journal Article ; Journal Article
    ZDB-ID 2026589-X
    ISSN 1092-0684 ; 1092-0684
    ISSN (online) 1092-0684
    ISSN 1092-0684
    DOI 10.3171/2024.3.FOCUS23735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Volumetric extent of resection and survival for recurrent atypical meningioma.

    Przybylowski, Colin J / Suki, Dima / Raza, Shaan M / DeMonte, Franco

    Journal of neurosurgery

    2023  Volume 139, Issue 3, Page(s) 769–779

    Abstract: Objective: In recurrent atypical meningioma, the survival impact of volumetric extent of resection (vEOR) and residual tumor volume (RTV) has not been previously studied.: Methods: The authors performed a retrospective vEOR analysis of patients with ... ...

    Abstract Objective: In recurrent atypical meningioma, the survival impact of volumetric extent of resection (vEOR) and residual tumor volume (RTV) has not been previously studied.
    Methods: The authors performed a retrospective vEOR analysis of patients with recurrent World Health Organization grade II meningiomas treated with reresection from 2000 to 2019. The Kaplan-Meier method and multivariate Cox regression analysis were used to study progression-free survival (PFS) and overall survival (OS).
    Results: Fifty-nine patients with a median follow-up duration of 95 (95% CI 42-148) months were included. The median (range) vEOR was 100% (32%-100%) and the mean ± SD was 90.7% ± 15.3%. Among patients who underwent gross-total resection (GTR) (n = 32 [54%]), Simpson grade I and II resections were achieved in 23 (72%) and 9 (28%) patients, respectively. Among patients who underwent subtotal resection (n = 27 [46%]), the median (range) RTV was 4.3 (0.3-40) cm3. The 1-, 2-, and 5-year actuarial PFS rates for the cohort were 76%, 56%, and 34%, respectively. The 1-, 2-, and 5-year actuarial OS rates for the cohort were 98%, 78%, and 60%, respectively. Variables reflecting EOR significantly impacted both PFS and OS in multivariate analysis: GTR (p < 0.01) was significantly associated with longer PFS, and lower Simpson grade (p = 0.04) was significantly associated with longer OS. Additional factors including RTV, Ki-67 index, and pretreatment and posttreatment history also impacted survival outcomes (p < 0.05).
    Conclusions: EOR and Simpson grade were independently associated with survival outcomes in patients with recurrent atypical meningioma. These findings support the practice of thorough reresection for maximal cytoreduction in appropriate surgical candidates.
    MeSH term(s) Humans ; Meningioma/pathology ; Meningeal Neoplasms/pathology ; Retrospective Studies ; Neurosurgical Procedures ; Progression-Free Survival ; Neoplasm Recurrence, Local/surgery ; Disease-Free Survival
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2022.12.JNS221815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.135: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Conference proceedings: Long-Term Prognostic Impact of the Dural Tail in the Local Control of Intracranial Meningiomas

    Rubino, Franco / de Almeida, Romulo A. Andrade / Komal, Shah / Raza, Shaan M. / DeMonte, Franco

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1780255
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3425: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Management of Skull Base Metastases.

    Mehta, Gautam U / Raza, Shaan M

    Neurosurgery clinics of North America

    2020  Volume 31, Issue 4, Page(s) 659–666

    Abstract: Autopsy studies suggest that skull base metastases are likely underrecognized in patients with cancer. Patients frequently present with one or a combination of skull base clinical syndromes that manifest as pain or cranial neuropathy. Once a skull base ... ...

    Abstract Autopsy studies suggest that skull base metastases are likely underrecognized in patients with cancer. Patients frequently present with one or a combination of skull base clinical syndromes that manifest as pain or cranial neuropathy. Once a skull base metastasis is suspected, establishing a histologic diagnosis, dedicated imaging, and restaging (if appropriate) are the first steps in management. A multidisciplinary approach should then be used to identify the optimal histology-based treatment strategy, taking into account the burden of systemic disease. Finally, definitive treatment may include one or a combination of surgical management, radiation therapy, or chemotherapy."
    MeSH term(s) Breast Neoplasms/pathology ; Humans ; Lung Neoplasms/pathology ; Skull Base Neoplasms/pathology ; Skull Base Neoplasms/secondary ; Skull Base Neoplasms/therapy ; Treatment Outcome
    Language English
    Publishing date 2020-08-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1196855-2
    ISSN 1558-1349 ; 1042-3680
    ISSN (online) 1558-1349
    ISSN 1042-3680
    DOI 10.1016/j.nec.2020.06.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 1200: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Olfactory groove and planum meningiomas.

    DeMonte, Franco / Raza, Shaan M

    Handbook of clinical neurology

    2020  Volume 170, Page(s) 3–12

    Abstract: Meningiomas of the olfactory groove and planum sphenoidale are relatively common skullbase meningiomas. They are typically of low grade but may grow to large size due to the insidious nature of their growth. Surgical resection remains the mainstay of ... ...

    Abstract Meningiomas of the olfactory groove and planum sphenoidale are relatively common skullbase meningiomas. They are typically of low grade but may grow to large size due to the insidious nature of their growth. Surgical resection remains the mainstay of treatment.
    MeSH term(s) Humans ; Magnetic Resonance Imaging ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/pathology ; Meningeal Neoplasms/surgery ; Meningioma/diagnostic imaging ; Meningioma/pathology ; Meningioma/surgery ; Neurosurgical Procedures ; Tomography, X-Ray Computed ; Treatment Outcome
    Language English
    Publishing date 2020-07-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-12-822198-3.00023-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Endoscopic endonasal transpterygoid approach to petrous pathologies: technique, limitations and alternative approaches.

    Mehta, Gautam U / Raza, Shaan M

    Journal of neurosurgical sciences

    2018  Volume 62, Issue 3, Page(s) 339–346

    Abstract: The endoscopic endonasal transpterygoid approach is a versatile technique, providing direct access to the petrous apex through an anterior surgical corridor. In this review we detail the transpterygoid approach to the petrous apex and highlight its ... ...

    Abstract The endoscopic endonasal transpterygoid approach is a versatile technique, providing direct access to the petrous apex through an anterior surgical corridor. In this review we detail the transpterygoid approach to the petrous apex and highlight its relative indications. Although this approach is a useful strategy for many lesions of the petrous apex, disease extension into lateral, superior, or posterior compartments may limit extent of resection afforded by an anterior approach alone. Based on these considerations, a disease compartment-specific strategy is discussed. The limitations of the transpterygoid approach and indications for lateral and postero-lateral approaches to petrous pathology are reviewed.
    MeSH term(s) Humans ; Natural Orifice Endoscopic Surgery/methods ; Neuroendoscopy/methods ; Petrous Bone/surgery ; Skull Base Neoplasms/surgery ; Skull Neoplasms/surgery
    Language English
    Publishing date 2018-01-10
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 193139-8
    ISSN 1827-1855 ; 0390-5616 ; 0026-4881
    ISSN (online) 1827-1855
    ISSN 0390-5616 ; 0026-4881
    DOI 10.23736/S0390-5616.18.04302-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.241: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Impact of Radiation Therapy on Outcomes After Spinal Instrumentation for Craniocervical Junction Malignancies.

    Muir, Matthew / Rhines, Laurence / Demonte, Franco / Tatsui, Claudio / Raza, Shaan M

    Neurospine

    2022  Volume 19, Issue 2, Page(s) 434–440

    Abstract: Objective: Spinal reconstruction after resection of invasive craniocervical junction malignancies is fraught with technical and management considerations as well as a paucity of data in the existing literature. In this study, we describe our experience ... ...

    Abstract Objective: Spinal reconstruction after resection of invasive craniocervical junction malignancies is fraught with technical and management considerations as well as a paucity of data in the existing literature. In this study, we describe our experience with craniocervical junction malignancies, especially the influence of radiation on the need for revision spinal instrumentation.
    Methods: We performed a retrospective chart review of all patients who underwent occipitocervical fixation between 2011 and 2019 at The University of Texas MD Anderson Cancer Center.
    Results: Twenty-five patients had primary malignancies and 12 (30%) had metastatic tumors. Thirteen (33%) underwent a staged resection in multiple operations during their hospital stay. Tumor resection was performed in 19 patients (48%), while only stabilization was performed in 21 patients (52%). Nine patients (23%) underwent expanded endoscopic transclival approaches for tumor resection, 10 patients (25%) an extreme lateral approach, and 2 patients (5%) an anterior open approach. Eleven patients underwent early postoperative radiation therapy (within 3 months) and 8 underwent delayed radiation therapy (between 3 months and 1 year in 7 patients). The revision rate was 8%, with a median time to revision surgery of 42 months. The administration and timing of adjuvant radiation therapy relative to surgery had no significant effect on the need for instrumentation revision on log-rank and Cox regression analyses (p < 0.05).
    Conclusion: Revision surgery was needed infrequently in our patients. Postoperative radiation therapy was not associated with hardware failure, indicating that the timing of radiation therapy should be dictated by the diagnosis and can be initiated postoperatively without delay.
    Language English
    Publishing date 2022-05-15
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3031654-6
    ISSN 2586-6591 ; 2586-6583
    ISSN (online) 2586-6591
    ISSN 2586-6583
    DOI 10.14245/ns.2244034.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Advances in the management of primary bone sarcomas of the skull base.

    Edem, Idara / DeMonte, Franco / Raza, Shaan M

    Journal of neuro-oncology

    2020  Volume 150, Issue 3, Page(s) 393–403

    Abstract: Skull base primary malignancies represent a heterogeneous group of histologic diagnoses and sarcomas of the skull base are specific malignant tumors that arise from mesenchymal cells and can be classified by site of origin into bony and soft tissue ... ...

    Abstract Skull base primary malignancies represent a heterogeneous group of histologic diagnoses and sarcomas of the skull base are specific malignant tumors that arise from mesenchymal cells and can be classified by site of origin into bony and soft tissue sarcomas. The most common bony sarcomas include: chondrosarcoma, osteosarcoma, chordoma, Ewing's sarcoma. Given the relative rarity of each histologic diagnosis, especially in the skull base, there is limited published data to guide the management of patients with skull base sarcomas. An electronic search of the literature was performed to obtain key publications in the management of bony sarcomas of the skull base published within the last decade. This article is thus a review of the multi-disciplinary management principles of primary bony sarcomas of the skull base. Of note, there have been several recent advancements in the realm of skull base sarcoma management that have resulted in improved survival. These include advances in: imaging and diagnostic techniques, surgical techniques that incorporate oncologic surgical principles, conformal radiation paradigms and targeted systemic therapies. Early access to coordinated multi-disciplinary subspecialty care immediately at suspicion of diagnosis has further improved outcomes. There are several ongoing trials in the realms of radiation therapy and systemic therapy that will hopefully provide further insight about the optimal management of bony sarcomas of the skull base.
    MeSH term(s) Animals ; Bone Neoplasms/pathology ; Bone Neoplasms/therapy ; Combined Modality Therapy ; Disease Management ; Humans ; Sarcoma/pathology ; Sarcoma/therapy ; Skull Base Neoplasms/pathology ; Skull Base Neoplasms/therapy
    Language English
    Publishing date 2020-04-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604875-4
    ISSN 1573-7373 ; 0167-594X
    ISSN (online) 1573-7373
    ISSN 0167-594X
    DOI 10.1007/s11060-020-03497-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1825: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Intracranial meningiomas: an update of the 2021 World Health Organization classifications and review of management with a focus on radiation therapy.

    Yarabarla, Varun / Mylarapu, Amrutha / Han, Tatiana J / McGovern, Susan L / Raza, Shaan M / Beckham, Thomas H

    Frontiers in oncology

    2023  Volume 13, Page(s) 1137849

    Abstract: Meningiomas account for approximately one third of all primary intracranial tumors. Arising from the cells of the arachnoid mater, these neoplasms are found along meningeal surfaces within the calvarium and spinal canal. Many are discovered incidentally, ...

    Abstract Meningiomas account for approximately one third of all primary intracranial tumors. Arising from the cells of the arachnoid mater, these neoplasms are found along meningeal surfaces within the calvarium and spinal canal. Many are discovered incidentally, and most are idiopathic, although risk factors associated with meningioma development include age, sex, prior radiation exposure, and familial genetic diseases. The World Health Organization grading system is based on histologic criteria, and are as follows: grade 1 meningiomas, a benign subtype; grade 2 meningiomas, which are of intermediately aggressive behavior and usually manifest histologic atypia; and grade 3, which demonstrate aggressive malignant behavior. Management is heavily dependent on tumor location, grade, and symptomatology. While many imaging-defined low grade appearing meningiomas are suitable for observation with serial imaging, others require aggressive management with surgery and adjuvant radiotherapy. For patients needing intervention, surgery is the optimal definitive approach with adjuvant radiation therapy guided by extent of resection, tumor grade, and location in addition to patient specific factors such as life expectancy. For grade 1 lesions, radiation can also be used as a monotherapy in the form of stereotactic radiosurgery or standard fractionated radiation therapy depending on tumor size, anatomic location, and proximity to dose-limiting organs at risk. Optimal management is paramount because of the generally long life-expectancy of patients with meningioma and the morbidity that can arise from tumor growth and recurrence as well as therapy itself.
    Language English
    Publishing date 2023-08-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1137849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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