Article: An Overview of the Long-term Follow-up of the Adult Post-kidney Transplant Recipients in Sudan: A Single-Center Experience.
2022 Volume 32, Issue 4, Page(s) 1065–1072
Abstract: Kidney transplant remains the definitive treatment for patients with end-stage renal disease. A retrospective cohort was conducted in Dr. Selma Center for Kidney Diseases (DSCKD) to determine the pattern of follow-up and outcomes of adult kidney ... ...
| Abstract | Kidney transplant remains the definitive treatment for patients with end-stage renal disease. A retrospective cohort was conducted in Dr. Selma Center for Kidney Diseases (DSCKD) to determine the pattern of follow-up and outcomes of adult kidney transplant recipients (KTRs) on long-term follow-up. Patients presented for follow-up during the period from January to June 2018 were studied regarding their demographic features, kidney transplant surgery, immunosuppressive therapy, graft function, and post-transplant complications. Data analysis was done using the Statistical Package for the Social Sciences version 16.0. During the study period, a total of 941 adult and pediatric KTR presented to DSCKD for follow-up. Only 792 KTRs were included in the study; those were adults, with their first kidney transplant, completed one year post-transplant, and agreed for enrollment. The mean age of the studied population was 47 ± 4.3 years. The majority were males, 74.2%. The median duration of follow-up was 7.4 years (interquartile range 3-11). Most transplants were through living-related donations, 78.8%. The combination of prednisolone, tacrolimus, and azathioprine remains the most common immunosuppressive regimen prescribed; delivered to 47.5% of recipients. Post-transplant complications were predominantly recurrent infections, diabetes mellitus, and hyperlipidemia seen in 54.5%, 42.4%, and 24.7% of recipients, respectively. On cross-comparisons living unrelated donor transplant recipients were found to have increased post-transplant complications, with a reduced kidney graft function at the end of the 1 |
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| MeSH term(s) | Adult ; Child ; Follow-Up Studies ; Graft Rejection ; Graft Survival ; Humans ; Immunosuppressive Agents/adverse effects ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Prospective Studies ; Retrospective Studies ; Sudan/epidemiology ; Transplant Recipients |
| Chemical Substances | Immunosuppressive Agents |
| Language | English |
| Publishing date | 2022-03-01 |
| Publishing country | Saudi Arabia |
| Document type | Journal Article ; Multicenter Study |
| ZDB-ID | 1379955-1 |
| ISSN | 1319-2442 |
| ISSN | 1319-2442 |
| DOI | 10.4103/1319-2442.338280 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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