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Article ; Online: Investigating Experimental Treatments for Rhinitis: A State-of-the-Art Systematic Review.

Sarfraz, Zouina / Sarfraz, Azza / Cherrez-Ojeda, Ivan

2024 , Page(s) 1455613231222363

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	750153-5
ISSN	1942-7522 ; 0145-5613
ISSN (online)	1942-7522
ISSN	0145-5613
DOI	10.1177/01455613231222363
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Article ; Online: Alexithymia prevalence in individuals with chronic urticaria and its association with illness severity and therapeutic profile.

Cherrez-Ojeda, Ivan / Thomsen, Simon Francis / Giménez-Arnau, Ana

The British journal of dermatology

2023 Volume 189, Issue 6, Page(s) 766–767

MeSH term(s)	Humans ; Affective Symptoms/epidemiology ; Prevalence ; Chronic Urticaria ; Urticaria/drug therapy ; Urticaria/epidemiology ; Patient Acuity ; Severity of Illness Index
Language	English
Publishing date	2023-08-01
Publishing country	England
Document type	Journal Article
ZDB-ID	80076-4
ISSN	1365-2133 ; 0007-0963
ISSN (online)	1365-2133
ISSN	0007-0963
DOI	10.1093/bjd/ljad272
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Article ; Online: The unusual experience of managing a severe COVID-19 case at home: what can we do and where do we go?

Chérrez-Ojeda, Ivan / Vanegas, Emanuel / Felix, Miguel

BMC infectious diseases

2020 Volume 20, Issue 1, Page(s) 862

Abstract: Background: The speed and reach of the COVID-19 pandemic has created special scenarios to be considered, such as those in where patients who meet criteria for hospitalization due to moderate/severe disease cannot be hospitalized due to economic ... ...

Abstract	Background: The speed and reach of the COVID-19 pandemic has created special scenarios to be considered, such as those in where patients who meet criteria for hospitalization due to moderate/severe disease cannot be hospitalized due to economic constraints and saturation of national health systems. The aim of this report is to present an unusual case of a severe COVID-19 patient managed at home in a developing country, and to discuss some of the available guidelines and potential therapeutic options for this type of cases. Case presentation: A 60-year-old female seeking medical attention through teleconsultation presents with profound dyspnea, oppressive chest pain, fatigue, episodic hallucinations, and difficulty sleeping, for what she originally sought medical attention at an ER but could not be admitted due to saturation of the health system. A positive PCR test for COVID-19, and a CT scan of the chest showing bilateral consolidations with ground-glass opacities confirmed the diagnosis. The patient was managed at home, with corticosteroids, nitazoxanide and a single dose of 40 mg of subcutaneous enoxaparin. Colchicine was added at the third day of treatment. Standard oxygen therapy through nasal cannula was also recommended. Daily follow-ups were established to monitor for signs of clinical improvement. Two weeks later from the initial consultation the patient presents marked improvement in her symptoms, as well as in her CT scan, which prompted in discontinuation of the medications and the oxygen therapy. Conclusions: There are several limitations in this report regarding the clinical data and the management, but such limitations do also reflect the state of emergency and the chaos that resides in the health care systems of developing nations. For the ambulatory care of COVID-19 patients, several aspects of disease management may differ from current guidelines and basic requirements may represent a huge challenge to cover. Further research is needed to assist physicians in the daily clinical decision making, to optimize patient outcomes, and to reduce the probability of adverse scenarios of patients with COVID-19 managed in the ambulatory setting.
MeSH term(s)	Adrenal Cortex Hormones/therapeutic use ; Ambulatory Care ; Antiparasitic Agents ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/pathology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Enoxaparin/therapeutic use ; Female ; Humans ; Middle Aged ; Oxygen Inhalation Therapy ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/pathology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Severity of Illness Index ; Telemedicine ; Thiazoles/therapeutic use ; Thorax/diagnostic imaging ; Tomography, X-Ray Computed
Chemical Substances	Adrenal Cortex Hormones ; Antiparasitic Agents ; Enoxaparin ; RNA, Viral ; Thiazoles ; nitazoxanide (SOA12P041N)
Keywords	covid19
Language	English
Publishing date	2020-11-19
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1471-2334
ISSN (online)	1471-2334
DOI	10.1186/s12879-020-05608-0
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Article ; Online: A Rare Case of an Abdominal Aneurysm in a Patient with Lymphangioleiomyomatosis: A Case Report.

Chérrez-Ojeda, Iván / Espinoza-Plaza, José / Cottin, Vincent / Chérrez, Sofía

The Permanente journal

2019 Volume 23

Abstract: Introduction: Lymphangioleiomyomatosis (LAM) is a multisystemic disorder characterized by the proliferation, metastasis, and infiltration of smooth muscle cells in the lung and other tissues. Although LAM is rarely seen in men, it is usually detected in ...

Abstract	Introduction: Lymphangioleiomyomatosis (LAM) is a multisystemic disorder characterized by the proliferation, metastasis, and infiltration of smooth muscle cells in the lung and other tissues. Although LAM is rarely seen in men, it is usually detected in women during the third decade of life. Renal microaneurysms have been reported in patients with LAM, but abdominal aneurysms have not. We describe a patient with a diagnosis of LAM who had an unusual aneurysm in the inferior pancreaticoduodenal artery. Case presentation: A 47-year-old Ecuadorian woman self-referred for a routine visit to her family physician. She had a history of allergy to nonsteroidal anti-inflammatory drugs, pneumothorax, bilateral pleurodesis, and LAM since 2007. For her annual follow-up, an ultrasonogram was recommended. The abdominal ultrasonographic report described "a mass with blood flow in the midabdomen." An abdominal computed tomography angiogram was performed and revealed a 2.6-cm aneurysm of the inferior pancreaticoduodenal artery. After diagnosis of arterial aneurysm, she underwent transcatheter arterial embolization and stent placement. She is currently healthy and carries out her activities normally. Discussion: Lymphangioleiomyomatosis is a rare lung disease of unknown etiology. Extrapulmonary manifestations include abdominal aneurysm. This type of lesion should be added to a search for aneurysms in all patients with LAM.
MeSH term(s)	Aneurysm/complications ; Aneurysm/diagnostic imaging ; Aneurysm/therapy ; Arteries/diagnostic imaging ; Arteries/surgery ; Duodenum/blood supply ; Duodenum/diagnostic imaging ; Duodenum/surgery ; Embolization, Therapeutic/methods ; Female ; Humans ; Lymphangioleiomyomatosis/complications ; Middle Aged ; Pancreas/blood supply ; Pancreas/diagnostic imaging ; Pancreas/surgery ; Stents ; Tomography, X-Ray Computed
Language	English
Publishing date	2019-04-02
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2062823-7
ISSN	1552-5775 ; 1552-5767
ISSN (online)	1552-5775
ISSN	1552-5767
DOI	10.7812/TPP/18-170
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Article ; Online: Unveiling motives for dentistry studies: psychometric validation of a comprehensive questionnaire among aspiring dental students.

Moncayo-Rizzo, Jorge / Alvarado-Villa, Geovanny / Cherrez-Ojeda, Iván / Gallardo, Juan Carlos / Velez Leon, Eleonor / Gonzalez Eras, Susana Patricia

BDJ open

2024 Volume 10, Issue 1, Page(s) 27

Abstract: Objective: The aim of this study is to develop and validate a questionnaire for dental students in Ecuador to assess their reasons to study dentistry.: Materials and methods: A 25-item questionnaire was developed by the authors based on similar ... ...

Abstract	Objective: The aim of this study is to develop and validate a questionnaire for dental students in Ecuador to assess their reasons to study dentistry. Materials and methods: A 25-item questionnaire was developed by the authors based on similar studies and a qualitative study. The questionnaire had five theoretical factors: economic, professional, vocational, social and academic reasons for study. In the first two samples, exploratory factor analysis was performed to identify the structure, and the models obtained were compared with confirmatory factor analysis in the third sample. Results: Three samples were used, sample A with 201 participants, sample B with 623 participants, and sample C with 596 participants. Two-thirds of the participants were female and almost one-third were from coast region. The EFA applied in sample A resulted in a five-factor model with 18 items; in contrast, a three-factor model was obtained from sample B. According to the CFA in sample C, the best model was explained by three factors: labor, vocational and academic reasons. Considering two items to cross-load in labor and vocational factors, which are theoretically justified. Conclusion: This study presents a 12-item questionnaire that assesses labor, vocational and academic reasons for studying dentistry in an Ecuadorian population.
Language	English
Publishing date	2024-03-28
Publishing country	England
Document type	Journal Article
ISSN	2056-807X
ISSN (online)	2056-807X
DOI	10.1038/s41405-024-00208-5
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Article: Seguimiento de los pacientes después de neumonía por COVID-19. Secuelas pulmonares.

Chérrez-Ojeda, Iván / Gochicoa-Rangel, Laura / Salles-Rojas, Antonio / Mautong, Hans

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

2021 Volume 67, Issue 4, Page(s) 350–369

Abstract: Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2 that has caused an unprecedented pandemic with a high rate of morbidity and mortality worldwide. Although most cases are mild, there are a considerable number of patients who ... ...

Title translation	Follow-up of patients after COVID-19 pneumonia. Pulmonary sequelae.
Abstract	Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2 that has caused an unprecedented pandemic with a high rate of morbidity and mortality worldwide. Although most cases are mild, there are a considerable number of patients who develop pneumonia or even acute respiratory distress syndrome (ARDS). After having recovered from the initial disease, many patients continue with various symptoms (fatigue, dry cough, fever, dyspnea, anosmia, and chest pain, among others.), which has led to consider the possible existence of "post-COVID-19 syndrome". Although the definition and validity of this syndrome are not clear yet, several studies report that individuals who have recovered from COVID-19 may have persistent symptoms, radiological abnormalities, and compromised respiratory function. Current evidence suggests that there is a large number of pulmonary sequelae after COVID-19 pneumonia (interstitial thickening, ground glass opacities, crazy paving pattern, and bronchiectasis, among others.). Likewise, it seems that pulmonary function tests (spirometry, DLCO, 6MWT, and measurement of maximum respiratory pressures), in addition to high-resolution computed axial tomographies (CAT scan), are useful for the assessment of these post-COVID-19 pulmonary sequelae. This review aims to describe the possible pulmonary sequelae after COVID-19 pneumonia, as well as to suggest diagnostic procedures for their correct assessment and follow-up; thus, allowing proper management by a multidisciplinary medical team.
MeSH term(s)	Bronchiectasis/diagnostic imaging ; Bronchiectasis/etiology ; Bronchiectasis/physiopathology ; COVID-19/complications ; Convalescence ; Disease Progression ; Follow-Up Studies ; Humans ; Hypoxia/blood ; Hypoxia/etiology ; Hypoxia/physiopathology ; Lung Diseases/diagnostic imaging ; Lung Diseases/etiology ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/etiology ; Lung Diseases, Interstitial/physiopathology ; Mental Disorders/etiology ; Mental Disorders/physiopathology ; Oxygen/blood ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/etiology ; Pulmonary Embolism/physiopathology ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/physiopathology ; Respiratory Function Tests ; Spirometry ; Tomography, X-Ray Computed
Chemical Substances	Oxygen (S88TT14065)
Language	Spanish
Publishing date	2021-02-26
Publishing country	Mexico
Document type	Journal Article ; Review
ZDB-ID	639125-4
ISSN	0002-5151
ISSN	0002-5151
DOI	10.29262/ram.v67i4.847
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Article: The radiological presentation of Rasmussen aneurysm secondary to pulmonary tuberculosis and COVID-19: A case report.

Arif, Adnan / Bhinder, Khurram Khaliq / Sarfraz, Azza / Sarfraz, Zouina / Felix, Miguel / Chérrez-Ojeda, Ivan

Radiology case reports

2021 Volume 16, Issue 11, Page(s) 3350–3353

Abstract: Rasmussen aneurysm is rare diagnosis occurring in patients with long-standing tuberculosis. TB-COVID-19 co-infection in the context of Rasmussen aneurysm is a rare occurrence, yet new cases are emerging. An elderly male was recently diagnosed with TB- ... ...

Abstract	Rasmussen aneurysm is rare diagnosis occurring in patients with long-standing tuberculosis. TB-COVID-19 co-infection in the context of Rasmussen aneurysm is a rare occurrence, yet new cases are emerging. An elderly male was recently diagnosed with TB-COVID-19 co-infection and presented with sudden onset massive hemoptysis. The patient was diagnosed with Rasmussen aneurysm after being evaluated by computed tomography pulmonary angiogram due to a suggestive clinical presentation. Interventional radiologists planned for embolization of pulmonary artery, with an unidentifiable source. It was suspected that the patient's source of bleeding was hampered due to local tamponade effect or thrombosis of the aneurysm. The patient remained stable after 24 hours on computed tomography pulmonary angiogram. Our case emphasizes the importance of Rasmussen aneurysm as a differential diagnosis when presented with a TB-COVID-19 co-infection and sudden onset of hemoptysis symptomatically and radiologically. The timely diagnosis and management are key to improve mortality.
Language	English
Publishing date	2021-08-06
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2406300-9
ISSN	1930-0433
ISSN	1930-0433
DOI	10.1016/j.radcr.2021.07.088
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Article ; Online: Reacciones cutáneas a la vacuna Pfizer-BioNTech contra COVID-19. Una experiencia ecuatoriana.

Chérrez-Ojeda, Iván / Robles-Velasco, Karla / Osorio, María F / Mejía-Leiva, Daniel / Chérrez, Annia / Chérrez, Sofía / Bernstein, Jonathan A / Sarfraz, Zouina / Félix, Miguel

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

2022 Volume 69, Issue 1, Page(s) 61–64

Abstract: Objetive: To assess cutaneous reactions after Pfizer-BioNTech COVID-19 vaccine administration.: Methods: A cross-sectional observational study was carried out in health workers belonging to the city of Guayaquil-Ecuador, from March to May 2021. The ... ...

Title translation	Skin reactions to the Pfizer-BioNTech vaccine for COVID-19. An Ecuadorian experience.
Abstract	Objetive: To assess cutaneous reactions after Pfizer-BioNTech COVID-19 vaccine administration. Methods: A cross-sectional observational study was carried out in health workers belonging to the city of Guayaquil-Ecuador, from March to May 2021. The participants were contacted through a local registry established by the Universidad Espíritu Santo. Frequencies and percentages were used to represent the proportions of nominal variables, while the mean and standard deviation were used for continuous data, given a normal sample distribution. Results: Local skin reactions were the most frequent, and included redness, edema, and itching. On the other hand, delayed large local skin reactions (generalized rash and pruritus, angioedema, urticaria, eczema, petechiae) were rare and occurred in less than 1.4% of participants, (95% CI = 0.69-1.00). Finally, we did not find cases of anaphylaxis or other life-threatening reactions requiring urgent attention after vaccination. Conclusions: Our findings suggest that local skin reactions occur in a minority of recipients and are often mild and self-limited.
MeSH term(s)	Humans ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Ecuador/epidemiology ; BNT162 Vaccine ; Cross-Sectional Studies ; Vaccines ; Pruritus
Chemical Substances	COVID-19 Vaccines ; BNT162 Vaccine ; Vaccines
Language	Spanish
Publishing date	2022-06-30
Publishing country	Mexico
Document type	Observational Study ; English Abstract ; Journal Article
ZDB-ID	639125-4
ISSN	2448-9190 ; 0002-5151
ISSN (online)	2448-9190
ISSN	0002-5151
DOI	10.29262/ram.v69i1.973
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Article: Food allergy: What are people looking for? An infodemiology study.

Robles-Velasco, Karla / Panchana-Lascano, Matias / Veintemilla-Burgos, Flavio / Hinostroza, Romina / Bernstein, Jonathan A / Cherrez-Ojeda, Ivan

Clinical and translational allergy

2023 Volume 13, Issue 12, Page(s) e12322

Language	English
Publishing date	2023-12-29
Publishing country	England
Document type	Letter
ZDB-ID	2630865-4
ISSN	2045-7022
ISSN	2045-7022
DOI	10.1002/clt2.12322
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Article: Vaping and smokeless tobacco control in South Asia: A policy review.

Azeem, Nishwa / Sarfraz, Zouina / Sarfraz, Azza / Hange, Namrata / Sarfraz, Muzna / Cherrez-Ojeda, Ivan

Annals of medicine and surgery (2012)

2022 Volume 81, Page(s) 104285

Abstract: High prevalence of tobacco use is seen in low- and middle-income countries (LMIC). In the recent years, tobacco users have switched to alternatives falling under the framework of electronic nicotine delivery systems (ENDS). This review provides an ... ...

Abstract	High prevalence of tobacco use is seen in low- and middle-income countries (LMIC). In the recent years, tobacco users have switched to alternatives falling under the framework of electronic nicotine delivery systems (ENDS). This review provides an overview of tobacco control-related policies in Bangladesh, India, and Pakistan, and suggested recommendations to bridge this gap to address Tobacco-free Nations. This paper's findings are relevant for developing countries worldwide that have a high tobacco-related health burden, a complex landscape of use, and inadequate resources to offer tobacco cessation and smokeless tobacco control.
Language	English
Publishing date	2022-08-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1016/j.amsu.2022.104285
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