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  1. Article ; Online: Data-Driven Approaches to Maximize the Impact of Pediatric Clinical Trials.

    Bourgeois, Florence T

    Pediatrics

    2022  Volume 149, Issue 4

    MeSH term(s) Child ; Clinical Trials as Topic ; Humans
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2021-055815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.131: Show issues Location:
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    Zs.MO 357: Show issues

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  2. Article ; Online: Advancing Equity in Medical Device Development for Children.

    Bourgeois, Florence T / Espinoza, Juan C

    JAMA pediatrics

    2023  Volume 177, Issue 6, Page(s) 561–562

    MeSH term(s) Child ; Humans ; Durable Medical Equipment
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701223-2
    ISSN 2168-6211 ; 2168-6203
    ISSN (online) 2168-6211
    ISSN 2168-6203
    DOI 10.1001/jamapediatrics.2023.0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: New legislation to promote paediatric studies for new cancer medicines.

    Hwang, Thomas J / Bourgeois, Florence T

    The Lancet. Oncology

    2022  Volume 23, Issue 8, Page(s) e368–e369

    MeSH term(s) Child ; European Union ; Humans ; Legislation, Drug ; Neoplasms/drug therapy
    Language English
    Publishing date 2022-07-25
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(22)00376-X
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    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  4. Article ; Online: Mental Health-Related Outpatient Visits Among Adolescents and Young Adults, 2006-2019.

    Ahn-Horst, Rosa Y / Bourgeois, Florence T

    JAMA network open

    2024  Volume 7, Issue 3, Page(s) e241468

    Abstract: Importance: Concerns over the mental health of young people have been increasing over the past decade, especially with the rise in mental health burden seen during the COVID-19 pandemic. Examining trends in mental health-related outpatient visits ... ...

    Abstract Importance: Concerns over the mental health of young people have been increasing over the past decade, especially with the rise in mental health burden seen during the COVID-19 pandemic. Examining trends in mental health-related outpatient visits provides critical information to elucidate contributing factors, identify vulnerable populations, and inform strategies to address the mental health crisis.
    Objective: To examine characteristics and trends in mental health-related outpatient visits and psychotropic medication use among US adolescents and young adults.
    Design, setting, and participants: A retrospective cross-sectional analysis of nationally representative data from the National Ambulatory Medical Care Survey, an annual probability sample survey, was conducted from January 2006 to December 2019. Participants included adolescents (age 12-17 years) and young adults (age 18-24 years) with office-based outpatient visits in the US. Data were analyzed from March 1, 2023, to September 15, 2023.
    Main outcomes and measures: Mental health-related outpatient visits were identified based on established sets of diagnostic codes for psychiatric disorders. Temporal trends in the annual proportion of mental health-related outpatient visits were assessed, including visits associated with use of psychotropic medications. Analyses were stratified by age and sex.
    Results: From 2006 to 2019, there were an estimated 1.1 billion outpatient visits by adolescents and young adults, of which 145.0 million (13.1%) were associated with a mental health condition (mean [SD] age, 18.4 [3.5] years; 74.0 million females [51.0%]). Mental health-related diagnoses were more prevalent among visits by male (16.8%) compared with female (10.9%) patients (P < .001). This difference was most pronounced among young adults, with 20.1% of visits associated with a psychiatric diagnosis among males vs 10.1% among females (P < .001). The proportion of mental health-related visits nearly doubled, from 8.9% in 2006 to 16.9% in 2019 (P < .001). Among all outpatient visits, 17.2% were associated with the prescription of at least 1 psychotropic medication, with significant increases from 12.8% to 22.4% by 2019 (P < .001).
    Conclusions and relevance: In this cross-sectional study, there were substantial increases in mental health-related outpatient visits and use of psychotropic medications, with greater overall burden among male patients. These findings provide a baseline for understanding post-pandemic shifts and suggest that current treatment and prevention strategies will need to address preexisting psychiatric needs in addition to the effects of the COVID-19 pandemic.
    MeSH term(s) Humans ; Adolescent ; Female ; Male ; Young Adult ; Child ; Adult ; Mental Health ; Cross-Sectional Studies ; Outpatients ; Pandemics ; Retrospective Studies ; COVID-19/epidemiology
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2024.1468
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Enrollment of Pediatric Patients in COVID-19 Interventional Trials.

    Ong, Mei-Sing / Wu, Ann Chen / Bourgeois, Florence T

    JAMA health forum

    2023  Volume 4, Issue 11, Page(s) e233939

    MeSH term(s) Child ; Humans ; COVID-19 ; Patient Selection ; Clinical Trials as Topic
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Journal Article
    ISSN 2689-0186
    ISSN (online) 2689-0186
    DOI 10.1001/jamahealthforum.2023.3939
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  6. Article ; Online: Clinical trials for paediatric cancers under new legislation in the USA.

    Hwang, Thomas J / Reaman, Gregory H / Bourgeois, Florence T

    The Lancet. Child & adolescent health

    2023  Volume 7, Issue 7, Page(s) e13

    MeSH term(s) Child ; Humans ; United States ; European Union ; Legislation, Drug ; Neoplasms/therapy
    Language English
    Publishing date 2023-06-22
    Publishing country England
    Document type Letter ; Comment
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(23)00125-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evaluation of Publication of Pediatric Drug Trials.

    Srivastava, Ananya / Bourgeois, Florence T

    JAMA network open

    2021  Volume 4, Issue 4, Page(s) e215829

    MeSH term(s) Child ; Child Health ; Cross-Sectional Studies ; Humans ; Pediatrics ; Pharmaceutical Preparations ; Publication Bias ; Publishing ; Research
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2021-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.5829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Data Sharing for Pediatric Clinical Trials Funded by the US National Institutes of Health.

    Narang, Claire / Ouvina, Michelle / Rees, Chris A / Bourgeois, Florence T

    JAMA network open

    2023  Volume 6, Issue 7, Page(s) e2325342

    MeSH term(s) United States ; Humans ; Child ; National Institutes of Health (U.S.) ; Information Dissemination
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.25342
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  9. Article ; Online: Dissemination of the Results of Pediatric Clinical Trials Funded by the US National Institutes of Health.

    Rees, Chris A / Narang, Claire / Westbrook, Adrianna / Bourgeois, Florence T

    JAMA

    2023  Volume 329, Issue 7, Page(s) 590–592

    MeSH term(s) Child ; Humans ; National Institutes of Health (U.S.)/economics ; Registries ; United States ; Clinical Trials as Topic/economics ; Information Dissemination
    Language English
    Publishing date 2023-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2022.24025
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  10. Article ; Online: Improving FDA postmarket adverse event reporting for medical devices.

    Wunnava, Susmitha / Miller, Timothy A / Bourgeois, Florence T

    BMJ evidence-based medicine

    2022  Volume 28, Issue 2, Page(s) 83–84

    Language English
    Publishing date 2022-02-17
    Publishing country England
    Document type Journal Article
    ISSN 2515-4478
    ISSN (online) 2515-4478
    DOI 10.1136/bmjebm-2021-111870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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