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  1. Article ; Online: SALGINLARIN ÖĞRETTİKLERİNDEN BİRİ

    KESKİNBORA, Kadircan

    Volume: 2, Issue: 1 9-32 ; 2667-5412 ; TIDE AcademIA Research

    SORUNUN KAYNAĞINI DENETLEMEK

    2020  

    Abstract: İnsanlık tarihi boyunca insanların kitlesel olarak hastalanmasına ve ölümüne yol açan salgınların nedenleri irdelendiğinde insanoğlunun ve canlıların yaşam rutinini bozan çeşitli doğal olaylar ile savaş, büyük yangınlar, çevre kirliliği ve benzeri insan ... ...

    Abstract İnsanlık tarihi boyunca insanların kitlesel olarak hastalanmasına ve ölümüne yol açan salgınların nedenleri irdelendiğinde insanoğlunun ve canlıların yaşam rutinini bozan çeşitli doğal olaylar ile savaş, büyük yangınlar, çevre kirliliği ve benzeri insan kaynaklı tahribatları gözlemleriz. İnsanın doğaya müdahalesi, doğal yaşamın, ekolojik dengenin, ekosistemlerin bozulmasına, eşitsizliklerin derinleşmesine yol açarak giderek büyüyen yıkımlara veya salgınlara neden olmaktadır.Büyük veya küçük çaplı olayların çözümünde, sorunlara çare aradığımızda, bilimden yararlanırız. Bilim; insanoğlu ve doğa mücadelesi veya dengesiyle ilgili korku, merak ve gözlemlere cevap arar, kendi yöntemleriyle sebep açıklama çalışmaları yapar. Daha rahat yaşam sürme, bazı doğal olaylara veya diğer canlılara karşı üstün olma gibi konularda da yol gösterir. Bilim etiğine saygı gösterilirse bu çaba dengeye, etiğin inkarında ise mücadeleye dönüşür.Eğer etik konular açık ve şeffaf bir biçimde pandemik plana dahil edilirse, toplumun birçok sektörünün de yardımıyla yapılan planlar daha büyük güven, otorite ve mantıkla yürütülebilecektir. Seçenekleri açıkça tartışmak ve toplum tarafından kabul edilen seçeneklerin etik değerlerin üzerine kurulu olduklarını teyit etmek toplumda önemli kazançlar sağlar. Bu makalede bütün dünyayı etkileyen bazı salgınlara ve sonuçlarına değindikten sonra, bilimin gelişimi, salgın yönetimi, kaynakların dağıtımı, pandemi etiği, uygarlık ürünleri gibi konulara kısaca değinilecektir.
    Keywords Adalet,COVID-19,Etik,Pamdemi,Sınırlı Kaynakların Kullanımı ; covid19
    Language Turkish
    Publishing date 2020-07-31T00:00:00Z
    Publisher Türkiye İç Denetim Enstitüsü
    Publishing country tr
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Ethical considerations on novel neuronal interfaces.

    Keskinbora, Kadircan H / Keskinbora, Kader

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2017  Volume 39, Issue 4, Page(s) 607–613

    Abstract: Wireless powered implants, each smaller than a grain of rice, have the potential to scan and stimulate brain cells. Further research may lead to next-generation brain-machine interfaces for controlling prosthetics, exoskeletons, and robots, as well as " ... ...

    Abstract Wireless powered implants, each smaller than a grain of rice, have the potential to scan and stimulate brain cells. Further research may lead to next-generation brain-machine interfaces for controlling prosthetics, exoskeletons, and robots, as well as "electroceuticals" to treat disorders of the brain and body. In conditions that can be particularly alleviated with brain stimulation, the use of such mini devices may pose certain challenges. Health professionals are becoming increasingly more accountable in decision-making processes that have impacts on the life quality of individuals. It is possible to transmit such stimulation using remote control principles. Perhaps, the most important concern regarding the use of these devices termed as "neural dust" is represented by the possibility of controlling affection and other mental functions via waves reaching the brain using more advanced versions of such devices. This will not only violate the respect for authority principle of ethics, but also medical ethics, and may potentially lead to certain incidents of varying vehemence that may be considered illegal. Therefore, a sound knowledge and implementation of ethical principles is becoming a more important issue on the part of healthcare professionals. In both the ethical decision-making process and in ethical conflicts, it may be useful to re-appraise the principles of medical ethics. In this article, the ethical considerations of these devices are discussed.
    MeSH term(s) Brain-Computer Interfaces ; Clinical Studies as Topic ; Decision Making/ethics ; Ethics, Medical ; Health Care Costs/statistics & numerical data ; Health Personnel/economics ; Health Personnel/ethics ; Health Personnel/statistics & numerical data ; Humans
    Language English
    Publishing date 2017-12-02
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-017-3209-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Maskless Fourier transform holography.

    Keskinbora, Kahraman / Levitan, Abraham L / Comin, Riccardo

    Optics express

    2022  Volume 30, Issue 1, Page(s) 403–413

    Abstract: Fourier transform holography is a lensless imaging technique that retrieves an object's exit-wave function with high fidelity. It has been used to study nanoscale phenomena and spatio-temporal dynamics in solids, with sensitivity to the phase component ... ...

    Abstract Fourier transform holography is a lensless imaging technique that retrieves an object's exit-wave function with high fidelity. It has been used to study nanoscale phenomena and spatio-temporal dynamics in solids, with sensitivity to the phase component of electronic and magnetic textures. However, the method requires an invasive and labor-intensive nanopatterning of a holography mask directly onto the sample, which can alter the sample properties, forces a fixed field-of-view, and leads to a low signal-to-noise ratio at high resolution. In this work, we propose using wavefront-shaping diffractive optics to create a structured probe with full control of its phase at the sample plane, circumventing the need for a mask. We demonstrate in silico that the method can image nanostructures and magnetic textures and validate our approach with a visible light-based experiment. The method enables investigation of a plethora of phenomena at the nanoscale including magnetic and electronic phase coexistence in solids, with further uses in soft and biological matter research.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.444455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Artificial Intelligence and Ophthalmology

    Keskinbora, Kadircan / Güven, Fatih

    Turkish journal of ophthalmology

    2020  Volume 50, Issue 1, Page(s) 37–43

    Abstract: Artificial intelligence is advancing rapidly and making its way into all areas of our lives. This review discusses developments and potential practices regarding the use of artificial intelligence in the field of ophthalmology, and the related topic of ... ...

    Abstract Artificial intelligence is advancing rapidly and making its way into all areas of our lives. This review discusses developments and potential practices regarding the use of artificial intelligence in the field of ophthalmology, and the related topic of medical ethics. Various artificial intelligence applications related to the diagnosis of eye diseases were researched in books, journals, search engines, print and social media. Resources were cross-checked to verify the information. Artificial intelligence algorithms, some of which were approved by the US Food and Drug Administration, have been adopted in the field of ophthalmology, especially in diagnostic studies. Studies are being conducted that prove that artificial intelligence algorithms can be used in the field of ophthalmology, especially in diabetic retinopathy, age-related macular degeneration, and retinopathy of prematurity. Some of these algorithms have come to the approval stage. The current point in artificial intelligence studies shows that this technology has advanced considerably and shows promise for future work. It is believed that artificial intelligence applications will be effective in identifying patients with preventable vision loss and directing them to physicians, especially in developing countries where there are fewer trained professionals and physicians are difficult to reach. When we consider the possibility that some future artificial intelligence systems may be candidates for moral/ethical status, certain ethical issues arise. Questions about moral/ethical status are important in some areas of applied ethics. Although it is accepted that current intelligence systems do not have moral/ethical status, it has yet to be determined what the exact the characteristics that confer moral/ethical status are or will be.
    MeSH term(s) Algorithms ; Artificial Intelligence ; Deep Learning ; Humans ; Ophthalmology/methods
    Language English
    Publishing date 2020-03-10
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 2586160-8
    ISSN 2149-8709 ; 2147-2661 ; 1300-0659 ; 1300-0659 ; 2149-8695
    ISSN (online) 2149-8709 ; 2147-2661 ; 1300-0659
    ISSN 1300-0659 ; 2149-8695
    DOI 10.4274/tjo.galenos.2020.78989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Rhazes' (865-925 CE) contribution to surgery in

    Ince, Fuat / Mahlooji, Kamran / Keskinbora, Kadircan H / Zargaran, Arman

    Acta chirurgica Belgica

    2022  Volume 123, Issue 2, Page(s) 212–217

    Abstract: Background: Surgery has deep historical roots. Rhazes (865-925 CE), a Persian physician, made a significant contribution to the development of medical sciences in the medieval era. : Method: This study examines Rhazes' contribution to surgery, based ... ...

    Abstract Background: Surgery has deep historical roots. Rhazes (865-925 CE), a Persian physician, made a significant contribution to the development of medical sciences in the medieval era.
    Method: This study examines Rhazes' contribution to surgery, based on his book,
    Results: Rhazes's
    Discussion: Although Rhazes mentioned surgical procedures as a medical treatment method, he did not include a separate chapter on surgery. This strategy can be found in his other medical works, such as
    MeSH term(s) Male ; Humans ; History, Medieval ; Medicine ; Medicine, Arabic/history ; Books
    Language English
    Publishing date 2022-12-30
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2022.2161035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Maskless off-axis X-ray Holography

    Keskinbora, Kahraman / Levitan, Abraham / Schütz, Gisela / Comin, Riccardo

    2021  

    Abstract: Off-axis X-ray holography is a lensless imaging technique that allows unambiguous retrieval of an object's exit-wave function with high fidelity. It has been used with great success to study nanoscale phenomena and spatio-temporal dynamics in solids, ... ...

    Abstract Off-axis X-ray holography is a lensless imaging technique that allows unambiguous retrieval of an object's exit-wave function with high fidelity. It has been used with great success to study nanoscale phenomena and spatio-temporal dynamics in solids, with sensitivity to the phase component of electronic and magnetic textures. However, the method requires patterning a nanostructured holography mask directly onto the sample. This invasive fabrication process is labor-intensive and defines a fixed field of view, limiting the range of applicable samples and diminishing the signal-to-noise ratio at high-resolution. In this work, we propose using wavefront-shaping X-ray diffractive optics to create a spatially structured probe with full control of its phase at the sample plane, obviating the need for a holography mask. We demonstrate in silico that the method can image nanoscale structures and magnetic textures. The proposed holography route can image extended regions of interest, enabling the investigation of a broad range of physical phenomena at the nanoscale including magnetism and electronic phase coexistence in quantum materials. We further envisage applications in phase-contrast imaging of other weakly absorbing objects in the realm of soft and biological matter research.

    Comment: 21 pages w/ supporting information, 8 figures total - 3 figures in main text
    Keywords Physics - Optics ; Condensed Matter - Materials Science
    Subject code 535
    Publishing date 2021-01-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Single-frame far-field diffractive imaging with randomized illumination.

    Levitan, Abraham L / Keskinbora, Kahraman / Sanli, Umut T / Weigand, Markus / Comin, Riccardo

    Optics express

    2020  Volume 28, Issue 25, Page(s) 37103–37117

    Abstract: We introduce a single-frame diffractive imaging method called randomized probe imaging (RPI). In RPI, a sample is illuminated by a structured probe field containing speckles smaller than the sample's typical feature size. Quantitative amplitude and phase ...

    Abstract We introduce a single-frame diffractive imaging method called randomized probe imaging (RPI). In RPI, a sample is illuminated by a structured probe field containing speckles smaller than the sample's typical feature size. Quantitative amplitude and phase images are then reconstructed from the resulting far-field diffraction pattern. The experimental geometry of RPI is straightforward to implement, requires no near-field optics, and is applicable to extended samples. When the resulting data are analyzed with a complimentary algorithm, reliable reconstructions which are robust to missing data are achieved. To realize these benefits, a resolution limit associated with the numerical aperture of the probe-forming optics is imposed. RPI therefore offers an attractive modality for quantitative X-ray phase imaging when temporal resolution and reliability are critical but spatial resolution in the tens of nanometers is sufficient. We discuss the method, introduce a reconstruction algorithm, and present two proof-of-concept experiments: one using visible light, and one using soft X-rays.
    Language English
    Publishing date 2020-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.397421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In Situ

    Dogan, Gül / Sanli, Umut T / Hahn, Kersten / Müller, Lutz / Gruhn, Herbert / Silber, Christian / Schütz, Gisela / Grévent, Corinne / Keskinbora, Kahraman

    ACS applied materials & interfaces

    2020  Volume 12, Issue 29, Page(s) 33377–33385

    Abstract: In many applications of copper in industry and research, copper migration and degradation of metallic copper to its oxides is a common problem. There are numerous ways to overcome this degradation with varying success. Atomic layer deposition (ALD) based ...

    Abstract In many applications of copper in industry and research, copper migration and degradation of metallic copper to its oxides is a common problem. There are numerous ways to overcome this degradation with varying success. Atomic layer deposition (ALD) based encapsulation and passivation of the metallic copper recently emerged as a serious route to success owing to the conformality and density of the ALD films. So far, the majority of the studies have been focused on corrosion protection of copper in a variety of chemical environments, mostly at ambient temperature. An investigation of the stability of the ALD film stacks and copper's interaction with them at elevated temperatures has been lacking. Here, we study the mitigation of copper oxidation and migration in 50 nm thick Al
    Language English
    Publishing date 2020-07-07
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.0c06873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Generation and characterization of focused helical x-ray beams.

    Loetgering, Lars / Baluktsian, Margarita / Keskinbora, Kahraman / Horstmeyer, Roarke / Wilhein, Thomas / Schütz, Gisela / Eikema, Kjeld S E / Witte, Stefan

    Science advances

    2020  Volume 6, Issue 7, Page(s) eaax8836

    Abstract: The phenomenon of orbital angular momentum (OAM) affects a variety of important applications in visible optics, including optical tweezers, free-space communication, and 3D localization for fluorescence imaging. The lack of suitable wavefront shaping ... ...

    Abstract The phenomenon of orbital angular momentum (OAM) affects a variety of important applications in visible optics, including optical tweezers, free-space communication, and 3D localization for fluorescence imaging. The lack of suitable wavefront shaping optics such as spatial light modulators has inhibited the ability to impart OAM on x-ray and electron radiation in a controlled way. Here, we report the experimental observation of helical soft x-ray beams generated by holographically designed diffractive optical elements. We demonstrate that these beams rotate as a function of propagation distance and measure their vorticity and coherent mode structure using ptychography. Our results establish an approach for controlling and shaping of complex focused beams for short wavelength scanning microscopy and OAM-driven applications.
    Language English
    Publishing date 2020-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.aax8836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: High-throughput synthesis of modified Fresnel zone plate arrays via ion beam lithography.

    Keskinbora, Kahraman / Sanli, Umut Tunca / Baluktsian, Margarita / Grévent, Corinne / Weigand, Markus / Schütz, Gisela

    Beilstein journal of nanotechnology

    2018  Volume 9, Page(s) 2049–2056

    Abstract: Fresnel zone plates (FZP) are diffractive photonic devices used for high-resolution imaging and lithography at short wavelengths. Their fabrication requires nano-machining capabilities with exceptional precision and strict tolerances such as those ... ...

    Abstract Fresnel zone plates (FZP) are diffractive photonic devices used for high-resolution imaging and lithography at short wavelengths. Their fabrication requires nano-machining capabilities with exceptional precision and strict tolerances such as those enabled by modern lithography methods. In particular, ion beam lithography (IBL) is a noteworthy method thanks to its robust direct writing/milling capability. IBL allows for rapid prototyping of high-resolution FZPs that can be used for high-resolution imaging at soft X-ray energies. Here, we discuss improvements in the process enabling us to write zones down to 15 nm in width, achieving an effective outermost zone width of 30 nm. With a 35% reduction in process time and an increase in resolution by 26% compared to our previous results, we were able to resolve 21 nm features of a test sample using the FZP. The new process conditions are then applied for fabrication of large arrays of high-resolution zone plates. Results show that relatively large areas can be decorated with nanostructured devices via IBL by using multipurpose SEM/FIB instruments with potential applications in FEL focusing, extreme UV and soft X-ray lithography and as wavefront sensing devices for beam diagnostics.
    Language English
    Publishing date 2018-07-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2583584-1
    ISSN 2190-4286
    ISSN 2190-4286
    DOI 10.3762/bjnano.9.194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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