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  1. Book ; Thesis: Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, Glibenclamide and GlyH-101

    Stahl, Maximilian / Stahl, Klaus

    2012  

    Author's details vorgelegt von Maximilian Stahl und Klaus Stahl
    Language English
    Size [13], 155 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2013
    Note Enth. Sonderabdr.
    HBZ-ID HT018307717
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 857 order for loan Magazin

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  2. Article ; Online: Is there a path forward for immunotherapy in patients with myelodysplastic syndromes?

    Stahl, Maximilian / DeZern, Amy E

    The Lancet. Haematology

    2023  Volume 11, Issue 1, Page(s) e5–e7

    MeSH term(s) Humans ; Myelodysplastic Syndromes/therapy ; Immunotherapy ; Patients
    Language English
    Publishing date 2023-12-05
    Publishing country England
    Document type Journal Article
    ISSN 2352-3026
    ISSN (online) 2352-3026
    DOI 10.1016/S2352-3026(23)00343-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute myeloid leukemia: 2023 update on diagnosis, risk-stratification, and management.

    Shimony, Shai / Stahl, Maximilian / Stone, Richard M

    American journal of hematology

    2023  Volume 98, Issue 3, Page(s) 502–526

    Abstract: Disease overview: Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell cancer characterized by unbridled proliferation of malignant marrow stem cells with associated infection, anemia, and bleeding. An improved understanding of ... ...

    Abstract Disease overview: Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell cancer characterized by unbridled proliferation of malignant marrow stem cells with associated infection, anemia, and bleeding. An improved understanding of pathophysiology, improvements in measurement technology and at least 10 recently approved therapies have led to revamping the diagnostic, prognostic, and therapeutic landscape of AML.
    Diagnosis: One updated and one new classification system were published in 2022, both emphasizing the integration of molecular analysis into daily practice. Differences between the International Consensus Classification and major revisions from the previous 2016 WHO system provide both challenges and opportunities for care and clinical research.
    Risk assessment and monitoring: The European Leukemia Net 2022 risk classification integrates knowledge from novel molecular findings and recent trial results, as well as emphasizing dynamic risk based on serial measurable residual disease assessment. However, how to leverage our burgeoning ability to measure a small number of potentially malignant myeloid cells into therapeutic decision making is controversial.
    Risk adapted therapy: The diagnostic and therapeutic complexity plus the availability of newly approved agents requires a nuanced therapeutic algorithm which should integrate patient goals of care, comorbidities, and disease characteristics including the specific mutational profile of the patient's AML. The framework we suggest only represents the beginning of the discussion.
    MeSH term(s) Humans ; Bone Marrow/pathology ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/therapy ; Mutation ; Prognosis ; Risk Assessment
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.26822
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    Zs.A 1251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Reconstructing Geometrical Models of Indoor Environments Based on Point Clouds

    Maximilian Kellner / Bastian Stahl / Alexander Reiterer

    Remote Sensing, Vol 15, Iss 4421, p

    2023  Volume 4421

    Abstract: In this paper, we present a workflow that combines supervised and unsupervised methods for the reconstruction of geometric models with architectural information from unordered 3D data. Our method uses a downsampling strategy to enrich features to provide ...

    Abstract In this paper, we present a workflow that combines supervised and unsupervised methods for the reconstruction of geometric models with architectural information from unordered 3D data. Our method uses a downsampling strategy to enrich features to provide scalability for large datasets, increase robustness, and be independent of the sensor used. A Neural Network is then used to segment the resulting point cloud into basic structures. This removes furniture and clutter and preserves the relevant walls, ceilings, floors, and openings. A 2D projection combined with a graph structure is used to find a Region of Interest within the cleaned point cloud, indicating a potential room. Each detected region is projected back into a 3D data patch to refine the room candidates and allow for more complex room structures. The resulting patches are fitted with a polygon using geometric approaches. In addition, architectural features, such as windows and doors, are added to the polygon. To demonstrate that the presented approach works and that the network provides usable results, even with changing data sources, we tested the approach in different real-world scenarios with different sensor systems.
    Keywords scene understanding ; point cloud ; deep learning ; Scan-to-BIM ; Science ; Q
    Subject code 006
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online ; Thesis: Digital Transformation in the Manufacturing Sector – Tackling Business and Technology Challenges

    Stahl, Bastian [Verfasser] / Röglinger, Maximilian [Akademischer Betreuer]

    2023  

    Author's details Bastian Stahl ; Betreuer: Maximilian Röglinger
    Keywords Wirtschaft ; Economics
    Subject code sg330
    Language English
    Publisher Universität Bayreuth
    Publishing place Bayreuth
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  6. Article ; Online: Systematic Review on Vestibular Symptoms in Patients With Enlarged Vestibular Aqueducts.

    Stahl, Maximilian C / Otteson, Todd

    The Laryngoscope

    2021  Volume 132, Issue 4, Page(s) 873–880

    Abstract: Objective: Enlarged vestibular aqueduct (EVA) is a congenital condition that can lead to various outcomes in pediatric patients including hearing loss and vestibular dysfunction. Our goal was to critically appraise the literature on the proportion of ... ...

    Abstract Objective: Enlarged vestibular aqueduct (EVA) is a congenital condition that can lead to various outcomes in pediatric patients including hearing loss and vestibular dysfunction. Our goal was to critically appraise the literature on the proportion of patients with EVA who report vestibular dysfunction, determine relevant risk factors for the development of these symptoms, and describe vestibular tests and interventions used to improve outcomes.
    Methods: A systematic review was performed in accordance with the PRISMA guidelines. We queried the EMBASE, Ovid Medline, and Cochrane Library databases for relevant literature. Studies were included if they had n > 10, reported vestibular symptoms or vestibular function testing in patients with EVA, and were published in English. Nonhuman studies, systematic reviews, and review articles were excluded.
    Results: Of 808 identified studies, 20 met inclusion criteria. Subjective vestibular symptoms included dizziness, episodic vertigo, and imbalance. Seventeen studies reported subjective vestibular symptoms, ranging from 2% to 71% of patients between studies. Seventeen studies performed some form of vestibular function test, including physical exam maneuvers (Dix-Hallpike), caloric testing, electronystagmography, and vestibular evoked myogenic potentials. Of those who had vestibular function testing, 7% to 92% had an abnormal result. Two studies identified head trauma as a risk factor. One study successfully treated patients with BPPV using the Epley maneuver, but other vestibular symptoms were not targeted with treatment.
    Conclusion: The degree to which vestibular symptoms impact patients with EVA varies significantly. Performing vestibular function testing may help identify asymptomatic patients with vestibular dysfunction. Future studies should target improving treatment of vestibular symptoms in EVA patients. Laryngoscope, 132:873-880, 2022.
    MeSH term(s) Child ; Hearing Loss, Sensorineural ; Humans ; Retrospective Studies ; Vertigo ; Vestibular Aqueduct/abnormalities ; Vestibule, Labyrinth
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29819
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    Ul II Zs.82: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Late and very late relapses in acute myeloid leukemia (AML).

    Stahl, Maximilian / Tallman, Martin Stuart

    Leukemia & lymphoma

    2020  Volume 61, Issue 5, Page(s) 1010–1011

    MeSH term(s) Chronic Disease ; Humans ; Leukemia, Myeloid, Acute ; Mutation ; Nuclear Proteins ; Recurrence
    Chemical Substances Nuclear Proteins
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2020.1745204
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    Zs.A 2997: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Outcomes of allogeneic stem cell transplantation for patients with t(6:9) AML- A strong case for allogeneic stem cell transplantation in first complete remission.

    Stahl, Maximilian / Tallman, Martin S

    British journal of haematology

    2020  Volume 189, Issue 5, Page(s) 806–808

    MeSH term(s) Chromosomal Proteins, Non-Histone ; Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia, Myeloid, Acute/therapy ; Nuclear Pore Complex Proteins ; Oncogene Proteins ; Poly-ADP-Ribose Binding Proteins ; Remission Induction
    Chemical Substances Chromosomal Proteins, Non-Histone ; DEK protein, human ; NUP214 protein, human ; Nuclear Pore Complex Proteins ; Oncogene Proteins ; Poly-ADP-Ribose Binding Proteins
    Language English
    Publishing date 2020-01-30
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16478
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    Uh III Zs.182: Show issues Location:
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  9. Article ; Online: Fused Projection-Based Point Cloud Segmentation.

    Kellner, Maximilian / Stahl, Bastian / Reiterer, Alexander

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 3

    Abstract: Semantic segmentation is used to enable a computer to understand its surrounding environment. In image processing, images are partitioned into segments for this purpose. State-of-the-art methods make use of Convolutional Neural Networks to segment a 2D ... ...

    Abstract Semantic segmentation is used to enable a computer to understand its surrounding environment. In image processing, images are partitioned into segments for this purpose. State-of-the-art methods make use of Convolutional Neural Networks to segment a 2D image. Compared to that, 3D approaches suffer from computational cost and are not applicable without any further steps. In this work, we focus on semantic segmentation based on 3D point clouds. We use the idea to project the 3D data into a 2D image to accelerate the segmentation process. Afterward, the processed image gets re-projected to receive the desired result. We investigate different projection views and compare them to clarify their strengths and weaknesses. To compensate for projection errors and the loss of geometrical information, we evolve the approach and show how to fuse different views. We have decided to fuse the bird's-eye and the spherical projection as each of them achieves reasonable results, and the two perspectives complement each other best. For training and evaluation, we use the real-world datasets SemanticKITTI. Further, we use the ParisLille and synthetic data generated by the simulation framework Carla to analyze the approaches in more detail and clarify their strengths and weaknesses. Although these methods achieve reasonable and competitive results, they lack flexibility. They depend on the sensor used and the setup in which the sensor is used.
    MeSH term(s) Image Processing, Computer-Assisted ; Neural Networks, Computer ; Semantics
    Language English
    Publishing date 2022-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22031139
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  10. Article ; Online: Measurable residual disease negativity in acute myeloid leukemia: the destination may matter more than the journey.

    Stahl, Maximilian / Tallman, Martin S / Goldberg, Aaron D

    Leukemia & lymphoma

    2021  Volume 62, Issue 9, Page(s) 2050–2051

    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/drug therapy ; Neoplasm, Residual
    Language English
    Publishing date 2021-09-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2021.1929967
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