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  1. Article: Differences in gene expression and variable splicing events of ovaries between large and small litter size in Chinese Xiang pigs.

    Ran, Xueqin / Hu, Fengbin / Mao, Ning / Ruan, Yiqi / Yi, Fanli / Niu, Xi / Huang, Shihui / Li, Sheng / You, Longjiang / Zhang, Fuping / Tang, Liangting / Wang, Jiafu / Liu, Jianfeng

    Porcine health management

    2021  Volume 7, Issue 1, Page(s) 52

    Abstract: ... of Xiang pig, we performed transcriptome analysis for the expression profile in ovaries using RNA-seq ... method.: Results: We identified 1,419 up-regulated and 1,376 down-regulated genes in Xiang pigs ... that might be related with the reproductive capability of Xiang pig, of which, eleven genes were recognized ...

    Abstract Background: Although lots of quantitative trait loci (QTLs) and genes present roles in litter size of some breeds, the information might not make it clear for the huge diversity of reproductive capability in pig breeds. To elucidate the inherent mechanisms of heterogeneity of reproductive capability in litter size of Xiang pig, we performed transcriptome analysis for the expression profile in ovaries using RNA-seq method.
    Results: We identified 1,419 up-regulated and 1,376 down-regulated genes in Xiang pigs with large litter size. Among them, 1,010 differentially expressed genes (DEGs) were differently spliced between two groups with large or small litter sizes. Based on GO and KEGG analysis, numerous members of genes were gathered in ovarian steroidogenesis, steroid biosynthesis, oocyte maturation and reproduction processes.
    Conclusions: Combined with gene biological function, twelve genes were found out that might be related with the reproductive capability of Xiang pig, of which, eleven genes were recognized as hub genes. These genes may play a role in promoting litter size by elevating steroid and peptide hormones supply through the ovary and facilitating the processes of ovulation and in vivo fertilization.
    Language English
    Publishing date 2021-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835354-7
    ISSN 2055-5660
    ISSN 2055-5660
    DOI 10.1186/s40813-021-00226-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differences in gene expression and variable splicing events of ovaries between large and small litter size in Chinese Xiang pigs

    Xueqin Ran / Fengbin Hu / Ning Mao / Yiqi Ruan / Fanli Yi / Xi Niu / Shihui Huang / Sheng Li / Longjiang You / Fuping Zhang / Liangting Tang / Jiafu Wang / Jianfeng Liu

    Porcine Health Management, Vol 7, Iss 1, Pp 1-

    2021  Volume 18

    Abstract: ... in litter size of Xiang pig, we performed transcriptome analysis for the expression profile in ovaries using RNA ... seq method. Results We identified 1,419 up-regulated and 1,376 down-regulated genes in Xiang pigs ... related with the reproductive capability of Xiang pig, of which, eleven genes were recognized as hub genes ...

    Abstract Abstract Background Although lots of quantitative trait loci (QTLs) and genes present roles in litter size of some breeds, the information might not make it clear for the huge diversity of reproductive capability in pig breeds. To elucidate the inherent mechanisms of heterogeneity of reproductive capability in litter size of Xiang pig, we performed transcriptome analysis for the expression profile in ovaries using RNA-seq method. Results We identified 1,419 up-regulated and 1,376 down-regulated genes in Xiang pigs with large litter size. Among them, 1,010 differentially expressed genes (DEGs) were differently spliced between two groups with large or small litter sizes. Based on GO and KEGG analysis, numerous members of genes were gathered in ovarian steroidogenesis, steroid biosynthesis, oocyte maturation and reproduction processes. Conclusions Combined with gene biological function, twelve genes were found out that might be related with the reproductive capability of Xiang pig, of which, eleven genes were recognized as hub genes. These genes may play a role in promoting litter size by elevating steroid and peptide hormones supply through the ovary and facilitating the processes of ovulation and in vivo fertilization.
    Keywords Transcriptome ; Alternative splicing ; Ovary ; Litter size ; Xiang pig ; Animal culture ; SF1-1100 ; Veterinary medicine ; SF600-1100
    Subject code 630
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Characteristics of High Quality Rice Xiang 5 and the Supporting Cultivation Techniques

    XU, Deze / CAI, Haiya / ZHAO, Feng / WU, Jianping / YOU, Aiqing

    2016  

    Abstract: The high quality rice, Xiang 5, is a new strain bred by Institute of Food Crops of Hubei Academy ... of Xiang 5 and main points of the supporting cultivation techniques, aimed at providing technical support ...

    Abstract The high quality rice, Xiang 5, is a new strain bred by Institute of Food Crops of Hubei Academy of Agricultural Sciences which first hybridizes Chinese scented rice with 9311, and then re-crosses it with Ezhong 5 for continuous generations. The strain has good quality, high yield, suitable maturity period, strong scent, strong combining ability and other features. This paper summarizes the appearance characteristics of Xiang 5 and main points of the supporting cultivation techniques, aimed at providing technical support and theoretical reference for its field production.
    Keywords High quality rice ; Xiang 5 ; Characteristics ; Cultivation techniques ; Agribusiness
    Language English
    Publishing country us
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Anxiolytic-like effects of compound zhi zhu xiang in rats.

    Wang, Yan-Li / Shi, Jin-Li / Yong, Liu / Ren, Zhao / Zhai, Yu-Jing / Guo, Jian-You

    Evidence-based complementary and alternative medicine : eCAM

    2012  Volume 2012, Page(s) 701289

    Abstract: The purpose of this study was to determine whether compound zhi zhu xiang (CZZX) exerts anxiolytic ...

    Abstract The purpose of this study was to determine whether compound zhi zhu xiang (CZZX) exerts anxiolytic-like effects in rats. The animals were orally administered CZZX (0.75, 1.5, and 3 g/kg daily) for 10 days and tested in the elevated plus maze (EPM), Vogel conflict test (VCT), and open field. Repeated treatment with CZZX (3 g/kg/day, p.o.) significantly increased the percentage of both entries into and time spent on the open arms of the EPM compared with saline controls. In the VCT, repeated treatment with CZZX (1.5 and 3 g/kg/day, p.o.) significantly increased the number of punished licks. The drug did not change the total entries into the open arms of the EPM or interfere with water consumption or nociceptive threshold, discarding potential confounding factors in the two tests. In the open field, locomotion was not reduced, discarding the possible sedative effect of CZZX. In the binding assay, the binding of [(3)H] Ro 15-1788 (flumazenil) to the benzodiazepine binding site in washed crude synaptosomal membranes from rat cerebral cortex was affected by CZZX. These data indicate an anxiolytic-like profile of action for CZZX without sedative side effects, and this activity may be mediated by benzodiazepine binding site modulation at γ-aminobutyric acid-A receptors.
    Language English
    Publishing date 2012-05-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2012/701289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Anxiolytic-Like Effects of Compound Zhi Zhu Xiang in Rats

    Yan-Li Wang / Jin-Li Shi / Liu Yong / Zhao Ren / Yu-Jing Zhai / Jian-You Guo

    Evidence-Based Complementary and Alternative Medicine, Vol

    2012  Volume 2012

    Abstract: The purpose of this study was to determine whether compound zhi zhu xiang (CZZX) exerts anxiolytic ...

    Abstract The purpose of this study was to determine whether compound zhi zhu xiang (CZZX) exerts anxiolytic-like effects in rats. The animals were orally administered CZZX (0.75, 1.5, and 3 g/kg daily) for 10 days and tested in the elevated plus maze (EPM), Vogel conflict test (VCT), and open field. Repeated treatment with CZZX (3 g/kg/day, p.o.) significantly increased the percentage of both entries into and time spent on the open arms of the EPM compared with saline controls. In the VCT, repeated treatment with CZZX (1.5 and 3 g/kg/day, p.o.) significantly increased the number of punished licks. The drug did not change the total entries into the open arms of the EPM or interfere with water consumption or nociceptive threshold, discarding potential confounding factors in the two tests. In the open field, locomotion was not reduced, discarding the possible sedative effect of CZZX. In the binding assay, the binding of [3H] Ro 15-1788 (flumazenil) to the benzodiazepine binding site in washed crude synaptosomal membranes from rat cerebral cortex was affected by CZZX. These data indicate an anxiolytic-like profile of action for CZZX without sedative side effects, and this activity may be mediated by benzodiazepine binding site modulation at γ-aminobutyric acid-A receptors.
    Keywords Other systems of medicine ; RZ201-999
    Subject code 630
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Nomogram model for the risk of insulin resistance in obese children and adolescents based on anthropomorphology and lipid derived indicators.

    You-Xiang, Cao / Lin, Zhu

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 275

    Abstract: Objective: This study aims to screen for measures and lipid-derived indicators associated with insulin resistance (IR) in obese children and adolescents and develop a nomogram model for predicting the risk of insulin resistance.: Methods: A total of ... ...

    Abstract Objective: This study aims to screen for measures and lipid-derived indicators associated with insulin resistance (IR) in obese children and adolescents and develop a nomogram model for predicting the risk of insulin resistance.
    Methods: A total of 404 eligible obese children and adolescents aged 10-17 years were recruited for this study from a summer camp between 2019 and 2021. The risk factors were screened using the least absolute shrinkage and selection operator (LASSO)-logistic regression model, and a nomogram model was developed. The diagnostic value of the model was evaluated by plotting the receiver operator characteristic curve and calculating the area under the curve. Internal validation was performed using the Bootstrap method, with 1000 self-samples to evaluate the model stability. The clinical applicability of the model was assessed by plotting the clinical decision curve.
    Results: On the basis of the LASSO regression analysis results, three lipid-related derivatives, TG/HDL-c, TC/HDL-c, and LDL-c/HDL-c, were finally included in the IR risk prediction model. The nomogram model AUC was 0.804 (95% CI: 0.760 to 0.849). Internal validation results show a C-Index of 0.799, and the mean absolute error between the predicted and actual risks of IR was 0.015. The results of the Hosmer-Lemeshow goodness-of-fit test show a good model prediction (χ
    Conclusion: Three early warning factors, TG/HDL-c, TC/HDL-c, and LDL-c/HDL-c, were screened, which can effectively predict the risk of developing IR in obese children and adolescents, and the nomogram model has an eligible diagnostic value.
    MeSH term(s) Humans ; Child ; Adolescent ; Insulin Resistance ; Nomograms ; Cholesterol, LDL ; Pediatric Obesity ; Risk Factors
    Chemical Substances Cholesterol, LDL
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-15181-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Microplastic Human Dietary Uptake from 1990 to 2018 Grew across 109 Major Developing and Industrialized Countries but Can Be Halved by Plastic Debris Removal.

    Zhao, Xiang / You, Fengqi

    Environmental science & technology

    2024  

    Abstract: Microplastics (MPs), plastic particles smaller than 5 mm, are now a growing environmental and public health issue, as they are detected pervasively in freshwater and marine environments, ingested by organisms, and then enter the human body. Industrial ... ...

    Abstract Microplastics (MPs), plastic particles smaller than 5 mm, are now a growing environmental and public health issue, as they are detected pervasively in freshwater and marine environments, ingested by organisms, and then enter the human body. Industrial development drives this environmental burden caused by MP formation and human uptake by elevating plastic pollution levels and shaping the domestic dietary structure. We map the MP human uptake across 109 global countries on five continents from 1990 to 2018, focusing on the world's major coastlines that are affected by plastic pollution that affects the United Nations' Sustainable Development Goals (SDGs): SDG 6 (Clean Water and Sanitation), SDG 14 (Life Below Water), and SDG 15 (Life on Land). Amid rapid industrial growth, Indonesia tops the global per capita MP dietary intake at 15 g monthly. In Asian, African, and American countries, including China and the United States, airborne and dietary MP uptake increased over 6-fold from 1990 to 2018. Eradicating 90% of global aquatic plastic debris can help decrease MP uptake by more than 48% in Southeast Asian countries that peak MP uptake. To reduce MP uptake and potential public health risks, governments in developing and industrialized countries in Asia, Europe, Africa, and North and South America should incentivize the removal of free plastic debris from freshwater and saltwater environments through advanced water treatment and effective solid waste management practices.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.4c00010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Emm

    Xiang, Caixin / Zhang, Jianzhong / Zhao, Fei / You, Yuanhai

    Frontiers in public health

    2023  Volume 11, Page(s) 1157289

    Abstract: Background: The recent increase of group A : Methods: We collected studies reporting GAS : Results: 47 high quality studies were included for a systematic analysis ... ...

    Abstract Background: The recent increase of group A
    Methods: We collected studies reporting GAS
    Results: 47 high quality studies were included for a systematic analysis of
    MeSH term(s) Humans ; Antigens, Bacterial/genetics ; Bacterial Outer Membrane Proteins/genetics ; Carrier Proteins/genetics ; Streptococcus pyogenes/genetics ; Streptococcal Infections/epidemiology ; Streptococcal Infections/prevention & control ; China/epidemiology
    Chemical Substances Antigens, Bacterial ; Bacterial Outer Membrane Proteins ; Carrier Proteins
    Language English
    Publishing date 2023-05-30
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1157289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Molecular Phylogenetics and the Evolution of Morphological Complexity in Aytoniaceae (Marchantiophyta).

    Xiang, You-Liang / Shen, Chao / Ma, Wen-Zhang / Zhu, Rui-Liang

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 8

    Abstract: Aytoniaceae are one of the largest families of complex thalloid liverworts (Marchantiopsida), consisting of about 70 species, with most species being distributed in temperate areas. However, the phylogeny and evolution of the morphological character of ... ...

    Abstract Aytoniaceae are one of the largest families of complex thalloid liverworts (Marchantiopsida), consisting of about 70 species, with most species being distributed in temperate areas. However, the phylogeny and evolution of the morphological character of Aytoniaceae are still poorly understood. Here, we employed two chloroplast loci, specifically,
    Language English
    Publishing date 2024-04-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13081053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Associations between MTHFR gene polymorphisms (C677T and A1298C) and genetic susceptibility to prostate cancer: a systematic review and meta-analysis.

    You, Jianan / Huang, Yuhua / Shen, Xinyu / Chen, Yunyi / Ding, Xiang

    Frontiers in genetics

    2024  Volume 15, Page(s) 1343687

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2024.1343687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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