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Article ; Online: Monitoring Multiple U.S. Government-Supported Covid-19 Vaccine Trials.

Hunsberger, Sally / Ellenberg, Susan S / Joffe, Steven / Babiker, Abdel / Fix, Alan / Griffin, Marie R / Kalil, Jorge / Levine, Myron M / Makgoba, Malegapuru W / Moore, Reneé H / Tsiatis, Anastasios A / Whitley, Richard

NEJM evidence

2023 Volume 2, Issue 3, Page(s) EVIDctcs2200301

Abstract: Monitoring U.S. Government-Supported Covid-19 Vaccine TrialsOperation Warp Speed was a partnership ...

Abstract	Monitoring U.S. Government-Supported Covid-19 Vaccine TrialsOperation Warp Speed was a partnership created to accelerate the development of Covid-19 vaccines. The National Institutes of Health oversaw one data and safety monitoring board to review/monitor all Operation Warp Speed trials. This article describes the challenges faced in monitoring these trials and provides ideas for future similar endeavors.
MeSH term(s)	United States ; Humans ; COVID-19 Vaccines ; COVID-19 ; Clinical Trials Data Monitoring Committees ; National Institutes of Health (U.S.)
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-02-28
Publishing country	United States
Document type	Journal Article
ISSN	2766-5526
ISSN (online)	2766-5526
DOI	10.1056/EVIDctcs2200301
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Article ; Online: The power of partnership: Exploring collaboration dynamics in U.S. transplant research.

Faria, Isabella / Montalvan, Adriana / Canizares, Stalin / Martins, Paulo N / Weber, Griffin M / Kazimi, Marwan / Eckhoff, Devin

American journal of surgery

2023 Volume 227, Page(s) 24–33

Abstract: ... collaboration patterns in U.S. transplant research, examining publication trends, productive institutions, co ... and international collaboration in U.S. transplant research. Understanding this community is essential ...

Abstract	Introduction: Collaboration is one of the hallmarks of academic research. This study analyzes collaboration patterns in U.S. transplant research, examining publication trends, productive institutions, co-authorship networks, and citation patterns in high-impact transplant journals. Methods: 4,265 articles published between 2012 and 2021 were analyzed using scientometric tools, logistic regression, VantagePoint software, and Gephi software for network visualization. Results: 16,003 authors from 1,011 institutions and 59 countries were identified, with Harvard, Johns Hopkins, and University of Pennsylvania contributing the most papers. Odds of international collaboration significantly increased over time (OR 1.03; p = 0.040), while odds of citation in single-institution collaborations decreased (OR 0.99; p = 0.016). Five major scientific communities and central institutions (Harvard University and University of Pittsburgh) connecting them were identified, revealing interconnected research clusters. Conclusions: Collaboration enhances knowledge exchange and research productivity, with an increasing trend of institutional and international collaboration in U.S. transplant research. Understanding this community is essential for promoting research impact and forming strategic partnerships.
MeSH term(s)	Humans ; Bibliometrics ; Authorship ; Organ Transplantation
Language	English
Publishing date	2023-10-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2953-1
ISSN	1879-1883 ; 0002-9610
ISSN (online)	1879-1883
ISSN	0002-9610
DOI	10.1016/j.amjsurg.2023.10.008
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Article: Feline abdominal ultrasonography: what’s normal? what’s abnormal? The adrenal glands

Griffin, Sally

Journal of feline medicine and surgery. 2021 Jan., v. 23, no. 1

2021

Abstract: ... from the published literature and the author’s own clinical experience. ...

Abstract	Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. Ultrasound examination of the adrenal glands can provide important information pertaining to several conditions including hyperaldosteronism and hyperadrenocorticism. Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even for the experienced ultrasonographer, differentiating between incidental findings, such as adrenal mineralisation, and clinically significant pathological changes can be challenging. This review, part of an occasional series on feline abdominal ultrasonography, discusses the ultrasonographic examination of the normal and diseased adrenal glands. Aimed at general practitioners who wish to improve their knowledge of and confidence in feline abdominal ultrasound, this review is accompanied by high-resolution images and videos available online as supplementary material. Ultrasound facilities are readily available to most practitioners, although the use of ultrasonography as a diagnostic tool is highly dependent on operator experience. Information provided in this article is drawn from the published literature and the author’s own clinical experience.
Keywords	adrenal glands ; cats ; diagnostic techniques ; general practitioners ; hyperadrenocorticism ; information ; knowledge ; literature ; medicine ; mineralization ; surgery ; ultrasonics ; ultrasonography
Language	English
Dates of publication	2021-01
Size	p. 33-49.
Publishing place	SAGE Publications
Document type	Article
Note	NAL-light
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X20979509
Database	NAL-Catalogue (AGRICOLA)

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Article: Feline abdominal ultrasonography: What’s normal? What’s abnormal? Abdominal lymph nodes, peritoneal cavity and aorta

Griffin, Sally

Journal of feline medicine and surgery. 2021 Sept., v. 23, no. 9

2021

Abstract: ... from the published literature and the author’s own clinical experience. ...

Abstract	Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. Ultrasound examination of the lymph nodes, peritoneal cavity and abdominal vasculature provides important information useful in the investigation of a number of conditions, including aortic thromboembolism. Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even for the experienced ultrasonographer, differentiating between incidental findings such as Bates bodies and pathological changes can be challenging. This review, the last in an occasional series on feline abdominal ultrasonography, discusses ultrasound examination of the abdominal lymph nodes and peritoneal cavity, and also the role of the technique in identifying thromboembolism of the aorta. Aimed at general practitioners who wish to improve their knowledge of and confidence in feline abdominal ultrasound, this review is accompanied by high-resolution images and videos available online as supplementary material. Ultrasound facilities are readily available to most practitioners, although the use of ultrasonography as a diagnostic tool is highly dependent on operator experience. Information provided in this article is drawn from the published literature and the author’s own clinical experience.
Keywords	aorta ; cats ; diagnostic techniques ; lymph ; medicine ; surgery ; ultrasonics ; ultrasonography
Language	English
Dates of publication	2021-09
Size	p. 835-849.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X211037874
Database	NAL-Catalogue (AGRICOLA)

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Article: Feline abdominal ultrasonography: what’s normal? what’s abnormal? The liver

Griffin, Sally

Journal of feline medicine and surgery. 2019 Jan., v. 21, no. 1

2019

Abstract: ... is drawn from the published literature and the author’s own clinical experience. ...

Abstract	Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. Ultrasound examination of the liver can be key in the diagnosis of diseases such as hepatic lipidosis and hepatic neoplasia. Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even differentiating between normal variation and pathological changes can be challenging for all but the most experienced. When assessing the liver via ultrasound, a diffuse alteration in liver echogenicity may be difficult to detect unless the change is marked and, although comparisons can be made with the spleen and kidneys, this relies on these organs being normal. Ultrasound facilities are readily available to most practitioners, although use of ultrasonography as a diagnostic tool is highly dependent on operator experience. This review, the first in an occasional series on feline abdominal ultrasonography, discusses ultrasonographic examination of the normal and diseased liver, with focus on the liver parenchyma. It is aimed at general practitioners who wish to improve their knowledge of and confidence in feline abdominal ultrasound and is accompanied by high-resolution images. Ultrasound-guided sampling of the liver is also covered. Future articles will discuss the biliary tree and hepatic vascular anomalies. Information provided in this article is drawn from the published literature and the author’s own clinical experience.
Keywords	biliary tract ; cats ; diagnostic techniques ; general practitioners ; kidneys ; liver ; neoplasms ; parenchyma (animal tissue) ; spleen ; ultrasonography
Language	English
Dates of publication	2019-01
Size	p. 12-24.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X18818666
Database	NAL-Catalogue (AGRICOLA)

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Article: Feline abdominal ultrasonography: what’s normal? what’s abnormal? The biliary tree

Griffin, Sally

Journal of feline medicine and surgery. 2019 May, v. 21, no. 5

2019

Abstract: ... in this article is drawn from the published literature and the author’s own clinical experience. ...

Abstract	Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. The biliary tree encompasses the liver, gall bladder and bile ducts, although only diseases affecting the latter two are discussed here. Diseases of the bile ducts and gall bladder are more common than those of the liver parenchyma and ultrasound plays an important role in their diagnosis. Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even differentiating between normal variation and pathological changes can be challenging for all but the most experienced. In addition, a lack of pathological change does not necessarily rule out disease; for example, absence of gall bladder and/or extrahepatic biliary distension is not sufficient to exclude the possibility of biliary obstruction, and in many cases of cholangitis the liver and biliary tree are unremarkable on ultrasound examination. Ultrasound facilities are readily available to most practitioners, although use of ultrasonography as a diagnostic tool is highly dependent on operator experience. This review, part of an occasional series on feline abdominal ultrasonography, discusses the appearance of the normal and diseased biliary system. It is aimed at general practitioners who wish to improve their knowledge and confidence in feline abdominal ultrasound and is accompanied by high-resolution images. Percutaneous ultrasound-guided cholecystocentesis is also covered. Ultrasound examination of the liver was discussed in an article published in January 2019 and an upcoming article will cover hepatic vascular anomalies. Information provided in this article is drawn from the published literature and the author’s own clinical experience.
Keywords	bile ducts ; cats ; cholestasis ; diagnostic techniques ; gall bladder ; general practitioners ; liver ; parenchyma (animal tissue) ; ultrasonography
Language	English
Dates of publication	2019-05
Size	p. 429-441.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X19843212
Database	NAL-Catalogue (AGRICOLA)

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Article: Feline abdominal ultrasonography: what’s normal? what’s abnormal? Hepatic vascular anomalies

Griffin, Sally

Journal of feline medicine and surgery. 2019 July, v. 21, no. 7

2019

Abstract: ... from the published literature and the author’s own clinical experience. ...

Abstract	Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. Although hepatic vascular anomalies are less common than disorders of the hepatic parenchyma and biliary tree, our understanding and recognition of these is gradually increasing with advancements in ultrasound technology and image quality. Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even differentiating between normal variation and pathological changes can be challenging for all but the most experienced. In addition, some views may be obscured by overlying structures; for example, the termination of a shunt entering the left phrenic or azygous veins is often difficut to see due to the high probability of lung passing between the shunt and the transducer as the cat breathes. Ultrasound facilities are readily available to most practitioners, although use of ultrasonography as a diagnostic tool is highly dependent on operator experience. This review, part of an occasional series on feline abdominal ultrasonography, discusses the appearance of various hepatic vascular anomalies. It is aimed at general practitioners who wish to improve their knowledge and confidence in feline abdominal ultrasound and is accompanied by high-resolution images. Ultrasound of the liver and biliary tree were discussed in articles published in January and May 2019, respectively. Information provided in this article is drawn from the published literature and the author’s own clinical experience.
Keywords	biliary tract ; cats ; diagnostic techniques ; general practitioners ; liver ; lungs ; parenchyma (animal tissue) ; probability ; ultrasonics ; ultrasonography
Language	English
Dates of publication	2019-07
Size	p. 645-654.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	2049047-1
ISSN	1532-2750 ; 1098-612X
ISSN (online)	1532-2750
ISSN	1098-612X
DOI	10.1177/1098612X19856182
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Characteristics of phantom limb pain in U.S. civilians and service members.

Griffin, Sarah C / Alphonso, Aimee L / Tung, Monica / Finn, Sacha / Perry, Briana N / Hill, Wendy / O'Connell, Colleen / Hanling, Steven R / Goff, Brandon J / Pasquina, Paul F / Tsao, Jack

Scandinavian journal of pain

2021 Volume 22, Issue 1, Page(s) 125–132

Abstract: ... missing limbs experience lower levels of PLP than those with amputation(s), yet PLP is common even ...

Abstract	Objectives: The population of Americans with limb loss is on the rise, with a different profile than in previous generations (e.g., greater incidence of amputation due to diabetes). This study aimed to identify the key characteristics of phantom limb sensation (PLS) and pain (PLP) in a current sample of Americans with limb loss. Methods: This cross-sectional study is the first large-scale (n=649) study on PLP in the current population of Americans with limb loss. A convenience sample of military and civilian persons missing one or more major limbs was surveyed regarding their health history and experience with phantom limb phenomena. Results: Of the participants surveyed, 87% experienced PLS and 82% experienced PLP. PLS and PLP typically first occurred immediately after amputation (47% of cases), but for a small percentage (3-4%) onset did not occur until over a year after amputation. Recent PLP severity decreased over time (β=0.028, 95% CI: -0.05-0.11), but most participants reported PLP even 10 years after amputation. Higher levels of recent PLP were associated with telescoping (β=0.123, 95% CI: 0.04-0.21) and higher levels of pre-amputation pain (β=0.104, 95% CI: 0.03-0.18). Those with congenitally missing limbs experienced lower levels of recent PLP (t (37.93)=3.93, p<0.01) but there were no consistent differences in PLP between other amputation etiologies. Conclusions: Phantom limb phenomena are common and enduring. Telescoping and pre-amputation pain are associated with higher PLP. Persons with congenitally missing limbs experience lower levels of PLP than those with amputation(s), yet PLP is common even in this subpopulation.
MeSH term(s)	Amputation, Surgical/adverse effects ; Amputees ; Cross-Sectional Studies ; Humans ; Incidence ; Phantom Limb/epidemiology ; Phantom Limb/etiology
Language	English
Publishing date	2021-09-16
Publishing country	Germany
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2515451-5
ISSN	1877-8879 ; 1877-8860
ISSN (online)	1877-8879
ISSN	1877-8860
DOI	10.1515/sjpain-2021-0139
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Article ; Online: Disentangling the Longitudinal Relationship between Loneliness and Depressive Symptoms in U.S. Adults Over 50.

Griffin, Sarah C / Blakey, Shannon M / Brant, Taylor R / Eshera, Yasmine M / Calhoun, Patrick S

Clinical gerontologist

2022 Volume 47, Issue 2, Page(s) 257–269

Abstract: Objectives: A seminal study on loneliness and depression suggested that loneliness influences depression more than the reverse. However, the study's analytic method has since been criticized for failing to account for the trait-like nature of variables. ...

Abstract	Objectives: A seminal study on loneliness and depression suggested that loneliness influences depression more than the reverse. However, the study's analytic method has since been criticized for failing to account for the trait-like nature of variables. This study aimed to examine the longitudinal relationship between loneliness and depressive symptoms while accounting for the trait-like nature of both variables. Methods: Data (n = 16,478) came from the Health and Retirement Study (2006-2016). Measures included the Hughes Loneliness Scale and a modified Center for Epidemiologic Studies Depression scale (loneliness item omitted). Analyses consisted of random intercepts cross-lagged panel models (three time-points evenly spaced across eight years). Results: There was evidence that loneliness and depressive symptoms are trait-like and these trait-like components are strongly associated. There was not evidence of cross-lagged effects between loneliness and depressive symptoms. Conclusions: A tendency toward loneliness corresponded with a tendency toward depressive symptoms. However, deviations in one's typical level of loneliness did not predict deviations in one's typical level of depressive symptoms or vice-versa. These findings do not support past assertions that loneliness shapes subsequent depression more than the reverse. Clinical implications: By middle to late adulthood, loneliness and depressive symptoms are trait-like phenomena that are strongly associated.
MeSH term(s)	Humans ; Adult ; Loneliness ; Depression/epidemiology ; Retirement
Language	English
Publishing date	2022-11-19
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	226146-7
ISSN	1545-2301 ; 0731-7115
ISSN (online)	1545-2301
ISSN	0731-7115
DOI	10.1080/07317115.2022.2147115
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Article ; Online: Strain of Multidrug-Resistant Salmonella Newport Remains Linked to Travel to Mexico and U.S. Beef Products - United States, 2021-2022.

MMWR. Morbidity and mortality weekly report

2023 Volume 72, Issue 45, Page(s) 1225–1229

Abstract: ... that is now monitored as a persisting strain (REPJJP01). Isolates have been obtained from U.S. residents ...

Abstract	In 2016, CDC identified a multidrug-resistant (MDR) strain of Salmonella enterica serotype Newport that is now monitored as a persisting strain (REPJJP01). Isolates have been obtained from U.S. residents in all 50 states and the District of Columbia, linked to travel to Mexico, consumption of beef products obtained in the United States, or cheese obtained in Mexico. In 2021, the number of isolates of this strain approximately doubled compared with the 2018-2020 baseline and remained high in 2022. During January 1, 2021- December 31, 2022, a total of 1,308 isolates were obtained from patients, cattle, and sheep; 86% were MDR, most with decreased susceptibility to azithromycin. Approximately one half of patients were Hispanic or Latino; nearly one half reported travel to Mexico during the month preceding illness, and one third were hospitalized. Two multistate outbreak investigations implicated beef products obtained in the United States. This highly resistant strain might spread through travelers, animals, imported foods, domestic foods, or other sources. Isolates from domestic and imported cattle slaughtered in the United States suggests a possible source of contamination. Safe food and drink consumption practices while traveling and interventions across the food production chain to ensure beef safety are necessary in preventing illness.
MeSH term(s)	United States/epidemiology ; Humans ; Cattle ; Animals ; Sheep ; Mexico/epidemiology ; Drug Resistance, Multiple, Bacterial ; Salmonella ; District of Columbia ; Salmonella enterica
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	412775-4
ISSN	1545-861X ; 0149-2195
ISSN (online)	1545-861X
ISSN	0149-2195
DOI	10.15585/mmwr.mm7245a3
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