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  1. Article ; Online: Moving towards deep equity, diversity, inclusivity and accessibility in simulation: a call to explore the promises and perils.

    Dieckmann, Peter / Nirula, Latika

    Advances in simulation (London, England)

    2024  Volume 9, Issue 1, Page(s) 6

    Abstract: Principles and issues of equity, diversity, inclusivity, and accessibility (EDIA) are being explored currently in simulation designs and trainings but with limited depth, often raising more questions than answers. This editorial invites the broader ... ...

    Abstract Principles and issues of equity, diversity, inclusivity, and accessibility (EDIA) are being explored currently in simulation designs and trainings but with limited depth, often raising more questions than answers. This editorial invites the broader healthcare simulation community to move beyond the superficial to explore more expansively and deeply these issues of EDIA within simulation. Simulation is the very environment and context from which we may confront how existing (power) structures can be dismantled and re-envisioned for more optimal redistribution of participation, power, and benefits. We can use simulation to experiment with variations of these realities, and start exploring consequences of such alternatives to benefit our broader health systems and societies. Simulation uniquely combines opportunities for experience, reflection, application and active experimentation, enabling a ripe ground for this study. In fact, it is the responsibility of simulation educators to take up this challenge, and to engage in meaningful scholarship to understand more about the impact of simulation in exploring EDIA topics. This editorial invites contributions of empirical and theoretical works that advance our collective understanding of EDIA, while also cautioning against complacency. The simulation community is urged to look inwards and also examine its own practices critically, in spite of the uncertainty, vulnerability and risks that this presents.
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Editorial
    ISSN 2059-0628
    ISSN (online) 2059-0628
    DOI 10.1186/s41077-024-00278-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Using simulations for education, training and research

    Dieckmann, Peter

    (Work research multidisciplinary ; 3)

    2009  

    Author's details Peter Dieckmann (ed.)
    Series title Work research multidisciplinary ; 3
    Collection
    Keywords Intensivmedizin ; Simulation
    Subject Simulationsexperiment ; Simulationsmethode ; Simulationsmodell ; Simulationstechnik
    Language English
    Size 216 S. : Ill., graph. Darst., 21 cm, 304 gr.
    Publisher Pabst Science Publ
    Publishing place Lengerich u.a.
    Publishing country Germany ; Austria
    Document type Book
    Note Literaturangaben
    HBZ-ID HT015965129
    ISBN 978-3-89967-539-9 ; 3-89967-539-8
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: The unexpected and the non-fitting - considering the edges of simulation as social practice.

    Dieckmann, Peter

    Advances in simulation (London, England)

    2020  Volume 5, Page(s) 2

    Language English
    Publishing date 2020-02-05
    Publishing country England
    Document type Editorial
    ISSN 2059-0628
    ISSN (online) 2059-0628
    DOI 10.1186/s41077-020-0120-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Does Testicular Seminoma Involve a Higher Predisposition Than Nonseminoma to Develop Contralateral Testicular Tumors?

    Dieckmann, Klaus-Peter

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2021  Volume 39, Issue 15, Page(s) 1689–1690

    MeSH term(s) Genotype ; Humans ; Male ; Seminoma ; Testicular Neoplasms/therapy
    Language English
    Publishing date 2021-03-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.20.03236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial Comment.

    Dieckmann, Klaus-Peter

    The Journal of urology

    2020  Volume 204, Issue 1, Page(s) 41

    MeSH term(s) Biopsy ; Prospective Studies
    Language English
    Publishing date 2020-04-08
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000000758.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Editorial Comment.

    Dieckmann, Klaus-Peter

    The Journal of urology

    2020  Volume 205, Issue 1, Page(s) 143–144

    MeSH term(s) Humans ; Male ; MicroRNAs ; Neoplasms, Germ Cell and Embryonal ; Orchiectomy ; Testicular Neoplasms
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2020-11-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000001337.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Thesis ; Online: Saisonale Häufung der Inzidenz von testikulären Keimzelltumoren

    Dieckmann, Klaus-Peter

    2022  

    Abstract: Der Datenempfänger hat beantragt, die monatlichen Inzidenzraten von Keimzelltumoren des Hodens (C62) der Jahre 2010 – 2019 zu erhalten. Zunächst soll untersucht werden, ob die einzelnen Monate Januar bis Dezember unterschiedliche Inzidenzraten aufweisen, ...

    Abstract Der Datenempfänger hat beantragt, die monatlichen Inzidenzraten von Keimzelltumoren des Hodens (C62) der Jahre 2010 – 2019 zu erhalten. Zunächst soll untersucht werden, ob die einzelnen Monate Januar bis Dezember unterschiedliche Inzidenzraten aufweisen, wobei ein Vergleich mit dem langjährigen monatlichen Mittelwert vorgenommen werden soll. In einem zweiten Schritt werden dann die kombinierten Inzidenzraten der dunklen Jahreszeiten (Oktober bis März) mit den Inzidenzraten der hellen Jahreszeiten (April bis September) verglichen. In weiteren Stratifizierungen soll untersucht werden, ob sich die monatlichen Inzidenzraten bei Seminomen (ICD-O-3: 9061-9063) von denen mit Nichtseminom (ICD-O-3: 9065 – 9085/3) unterscheiden. Außerdem soll untersucht werden, ob sich ältere Patienten (>40 Jahre) von den jüngeren (<40 Jahre) unterscheiden. Der Antrag war teilweise abzulehnen, soweit er die monatlichen Inzidenzraten von Keimzelltumoren des Hodens (C62) des Diagnosejahres 2020 zum Gegenstand hat, da dem ZfKD keine entsprechenden Daten für dieses Jahr vorliegen.
    Keywords 610 Medizin und Gesundheit ; ddc:610
    Language German
    Publisher Robert Koch-Institut
    Publishing country de
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The unexpected and the non-fitting – considering the edges of simulation as social practice

    Peter Dieckmann

    Advances in Simulation, Vol 5, Iss 1, Pp 1-

    2020  Volume 4

    Keywords Computer applications to medicine. Medical informatics ; R858-859.7
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Die Urologie – ein persönlicher Rückblick und ein vorsichtiger Blick in die Zukunft.

    Dieckmann, Klaus-Peter

    Der Urologe. Ausg. A

    2019  Volume 58, Issue 5, Page(s) 564–567

    Title translation Clinical Urology - a personal review of four decades and a careful look to the near future.
    MeSH term(s) Delivery of Health Care ; Forecasting ; Humans ; Urologists ; Urology/education ; Urology/trends
    Language German
    Publishing date 2019-03-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 204041-4
    ISSN 1433-0563 ; 0340-2592 ; 0375-4685
    ISSN (online) 1433-0563
    ISSN 0340-2592 ; 0375-4685
    DOI 10.1007/s00120-019-0911-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX), an ancillary tool for the macromolecular crystallography beamlines at the ESRF.

    Carpentier, Philippe / van der Linden, Peter / Mueller-Dieckmann, Christoph

    Acta crystallographica. Section D, Structural biology

    2024  Volume 80, Issue Pt 2, Page(s) 80–92

    Abstract: This article describes the High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX) at the ESRF, and highlights new and complementary research opportunities that can be explored using this facility. The laboratory is dedicated to ... ...

    Abstract This article describes the High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX) at the ESRF, and highlights new and complementary research opportunities that can be explored using this facility. The laboratory is dedicated to investigating interactions between macromolecules and gases in crystallo, and finds applications in many fields of research, including fundamental biology, biochemistry, and environmental and medical science. At present, the HPMX laboratory offers the use of different high-pressure cells adapted for helium, argon, krypton, xenon, nitrogen, oxygen, carbon dioxide and methane. Important scientific applications of high pressure to macromolecules at the HPMX include noble-gas derivatization of crystals to detect and map the internal architecture of proteins (pockets, tunnels and channels) that allows the storage and diffusion of ligands or substrates/products, the investigation of the catalytic mechanisms of gas-employing enzymes (using oxygen, carbon dioxide or methane as substrates) to possibly decipher intermediates, and studies of the conformational fluctuations or structure modifications that are necessary for proteins to function. Additionally, cryo-cooling protein crystals under high pressure (helium or argon at 2000 bar) enables the addition of cryo-protectant to be avoided and noble gases can be employed to produce derivatives for structure resolution. The high-pressure systems are designed to process crystals along a well defined pathway in the phase diagram (pressure-temperature) of the gas to cryo-cool the samples according to the three-step `soak-and-freeze method'. Firstly, crystals are soaked in a pressurized pure gas atmosphere (at 294 K) to introduce the gas and facilitate its interactions within the macromolecules. Samples are then flash-cooled (at 100 K) while still under pressure to cryo-trap macromolecule-gas complexation states or pressure-induced protein modifications. Finally, the samples are recovered after depressurization at cryo-temperatures. The final section of this publication presents a selection of different typical high-pressure experiments carried out at the HPMX, showing that this technique has already answered a wide range of scientific questions. It is shown that the use of different gases and pressure conditions can be used to probe various effects, such as mapping the functional internal architectures of enzymes (tunnels in the haloalkane dehalogenase DhaA) and allosteric sites on membrane-protein surfaces, the interaction of non-inert gases with proteins (oxygen in the hydrogenase ReMBH) and pressure-induced structural changes of proteins (tetramer dissociation in urate oxidase). The technique is versatile and the provision of pressure cells and their application at the HPMX is gradually being extended to address new scientific questions.
    MeSH term(s) Freezing ; Crystallography, X-Ray ; Helium ; Argon ; Carbon Dioxide ; Proteins/chemistry ; Oxygen ; Methane
    Chemical Substances Helium (206GF3GB41) ; Argon (67XQY1V3KH) ; Carbon Dioxide (142M471B3J) ; Proteins ; Oxygen (S88TT14065) ; Methane (OP0UW79H66)
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2968623-4
    ISSN 2059-7983 ; 0907-4449
    ISSN (online) 2059-7983
    ISSN 0907-4449
    DOI 10.1107/S2059798323010707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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