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  1. Book ; Online ; E-Book: The Mayo Clinic cardiac catheterization laboratory

    Holmes, David R.

    history, research, and innovations

    2021  

    Institution Mayo Clinic
    Mayo Clinic
    Author's details David R. Holmes Jr. [and five others], editors
    Keywords Cardiac catheterization ; Cateterisme cardíac ; Laboratoris clínics
    Subject code 362.1109776155
    Language English
    Size 1 online resource (382 pages)
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-79329-X ; 9783030793289 ; 978-3-030-79329-6 ; 3030793281
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article ; Online: Antithrombotic Therapy After Left Atrial Appendage Occlusion: Cornucopia and Gertrude Stein.

    Holmes, David R

    Journal of the American College of Cardiology

    2022  Volume 79, Issue 18, Page(s) 1799–1801

    MeSH term(s) Anticoagulants ; Atrial Appendage/surgery ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/surgery ; Fibrinolytic Agents/therapeutic use ; Humans ; Stroke ; Treatment Outcome
    Chemical Substances Anticoagulants ; Fibrinolytic Agents
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.03.328
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  3. Book: The Mayo Clinic Cardiac Catheterization Laboratory

    Holmes Jr., David R. / Frye, Robert L. / Ritman, Erik L. / Hagler, Donald J / Munger, Thomas M. / Friedman, Paul A.

    History, Research, and Innovations

    2021  

    Author's details Dr. David R. Holmes, Jr - Dr. Holmes is currently a Professor of Medicine at the Mayo Clinic College of Medicine and a consultant in the Department of Cardiovascular Medicine at Mayo Clinic in Rochester, Minnesota. Dr. Holmes has also been named the Edward W. and Betty Knight Scripps Professor in Cardiovascular Medicine in Honor of Dr. George M. Gura, Jr. He was the Director of the Cardiac Catheterization Laboratory from 1984-2003. He was awarded an Honorary Fellowship of the Royal College of Physicians in Ireland in November 2011. He has received the Distinguished Scientist Award (Clinical Domain) from the American College of Cardiology and the Research Career Achievement Award from the Mayo Graduate School of Medicine. He is a Past President of the American College of Cardiology (ACC) as well as the Society for Cardiac Angiography and Interventions (SCAI). He has received the Herrick Award from the American Heart Association. Dr. Holmes continues to lecture both nationally and
    Keywords Mayo Clinic Catheterization Laboratory ; Cardiovascular Disease ; E.H. Wood ; Stroke prevention ; First AV nodal ablation ; First catheter ablation for ventricular tachycardia ; First Pacemaker ; Electronic and imaging methodology ; Computed Tomography ; congenital heart disease ; Coronary Heart Disease ; hemodynamics ; Indocyanine Green dye ; Cardioversion ; Video densitometry technique ; Right and Left heart catheterization ; Satellite transmission ; New innovation treatment strategies ; The first clinical CT (the Dynamic Spatial Reconstructor) ; Stent Implantation ; Cardiovascular disease ; Congenital heart disease ; Coronary heart disease ; Hemodynamics ; Stent implantation
    Language English
    Size 396 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_12
    Format 160 x 241 x 22
    ISBN 9783030793289 ; 3030793281
    Database PDA

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  4. Article ; Online: Identification of Sleep Patterns via Clustering of Hypnodensities.

    Mirth, Joshua R / Felton, Christopher L / Haider, Clifton R / McCarter, Stuart J / Morgenthaler, Timothy I / Louis, Erik K St / Holmes, David R

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2023  Volume 2023, Page(s) 1–4

    Abstract: Sleep patterns vary widely between individuals. We explore methods for identifying populations exhibiting similar sleep patterns in an automated fashion using polysomnography data. Our novel approach applies unsupervised machine learning algorithms to ... ...

    Abstract Sleep patterns vary widely between individuals. We explore methods for identifying populations exhibiting similar sleep patterns in an automated fashion using polysomnography data. Our novel approach applies unsupervised machine learning algorithms to hypnodensities graphs generated by a pre-trained neural network. In a population of 100 subjects we identify two stable clusters whose characteristics we visualize graphically and through estimates of total sleep time. We also find that the hypnodensity representation of the sleep stages produces more robust clustering results than the same methods applied to traditional hypnograms.
    MeSH term(s) Humans ; Neural Networks, Computer ; Polysomnography/methods ; Sleep Stages ; Algorithms ; Cluster Analysis
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Journal Article
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC40787.2023.10340905
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  5. Article ; Online: Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline: 2024 Amendment.

    Holzbeierlein, Jeffrey M / Bixler, Brooke R / Buckley, David I / Chang, Sam S / Holmes, Rebecca / James, Andrew C / Kirkby, Erin / McKiernan, James M / Schuckman, Anne K

    The Journal of urology

    2024  Volume 211, Issue 4, Page(s) 533–538

    Abstract: Purpose: The purpose of this American Urological Association (AUA)/Society of Urologic Oncology (SUO) guideline amendment is to provide a useful reference on the effective evidence-based treatment strategies for non-muscle invasive bladder cancer (NMIBC) ...

    Abstract Purpose: The purpose of this American Urological Association (AUA)/Society of Urologic Oncology (SUO) guideline amendment is to provide a useful reference on the effective evidence-based treatment strategies for non-muscle invasive bladder cancer (NMIBC).
    Materials and methods: In 2023, the NMIBC guideline was updated through the AUA amendment process in which newly published literature is reviewed and integrated into previously published guidelines in an effort to maintain currency. The amendment allowed for the incorporation of additional literature released since the previous 2020 amendment. The updated search gathered literature from July 2019 to May 2023. This review identified 1918 abstracts, of which 75 met inclusion criteria.When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) in support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions.
    Results: Updates were made to statements on variant histologies, urine markers after diagnosis of bladder cancer, intravesical therapy, BCG maintenance, enhanced cystoscopy, and future directions. Further revisions were made to the methodology and reference sections as appropriate.
    Conclusions: This guideline seeks to improve clinicians' ability to evaluate and treat patients with NMIBC based on currently available evidence. Future studies will be essential to further support or refine these statements to improve patient care.
    MeSH term(s) Humans ; Non-Muscle Invasive Bladder Neoplasms ; Urinary Bladder Neoplasms/diagnosis ; Urinary Bladder Neoplasms/therapy ; Urology ; Cystoscopy ; Treatment Outcome
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003846
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  6. Article ; Online: Experience with a hybrid recruitment approach of patient-facing web portal screening and subsequent phone and medical record review for a neurosurgical intervention trial for chronic ischemic stroke disability (PISCES III).

    Kolls, Brad J / Muir, Keith W / Savitz, Sean I / Wechsler, Lawrence R / Pilitsis, Julie G / Rahimi, Scott / Beckman, Richard L / Holmes, Vincent / Chen, Peng R / Albers, David S / Laskowitz, Daniel T

    Trials

    2024  Volume 25, Issue 1, Page(s) 150

    Abstract: Background: Recruitment of participants is the greatest risk to completion of most clinical trials, with 20-40% of trials failing to reach the targeted enrollment. This is particularly true of trials of central nervous system (CNS) therapies such as ... ...

    Abstract Background: Recruitment of participants is the greatest risk to completion of most clinical trials, with 20-40% of trials failing to reach the targeted enrollment. This is particularly true of trials of central nervous system (CNS) therapies such as intervention for chronic stroke. The PISCES III trial was an invasive trial of stereotactically guided intracerebral injection of CTX0E03, a fetal derived neural stem cell line, in patients with chronic disability due to ischemic stroke. We report on the experience using a novel hybrid recruitment approach of a patient-facing portal to self-identify and perform an initial screen for general trial eligibility (tier 1), followed by phone screening and medical records review (tier 2) prior to a final in-person visit to confirm eligibility and consent.
    Methods: Two tiers of screening were established: an initial screen of general eligibility using a patient-facing web portal (tier 1), followed by a more detailed screen that included phone survey and medical record review (tier 2). If potential participants passed the tier 2 screen, they were referred directly to visit 1 at a study site, where final in-person screening and consent were performed. Rates of screening were tracked during the period of trial recruitment and sources of referrals were noted.
    Results: The approach to screening and recruitment resulted in 6125 tier 1 screens, leading to 1121 referrals to tier 2. The tier 2 screening resulted in 224 medical record requests and identification of 86 qualifying participants for referral to sites. The study attained a viable recruitment rate of 6 enrolled per month prior to being disrupted by COVID 19.
    Conclusions: A tiered approach to eligibility screening using a hybrid of web-based portals to self-identify and screen for general eligibility followed by a more detailed phone and medical record review allowed the study to use fewer sites and reduce cost. Despite the difficult and narrow population of patients suffering moderate chronic disability from stroke, this strategy produced a viable recruitment rate for this invasive study of intracranially injected neural stem cells.
    Trial registration: ClinicalTrials.gov Identifier: NCT03629275.
    MeSH term(s) Humans ; Ischemic Stroke ; Patient Selection ; Research Design ; Stroke/diagnosis ; Stroke/therapy ; Medical Records
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-024-07988-z
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  7. Article ; Online: Randomized trial of gastric and colorectal endoscopic submucosal dissection defect closure comparing a novel through-the-scope suturing system with an over-the-scope suturing system (with video).

    Agnihotri, Abhishek / Mitsuhashi, Shuji / Holmes, Ian / Kamal, Faisal / Chiang, Austin / Loren, David E / Kowalski, Thomas E / Schlachterman, Alexander / Kumar, Anand R

    Gastrointestinal endoscopy

    2023  Volume 99, Issue 2, Page(s) 237–244.e1

    Abstract: Background and aims: Mucosal closure adds time but reduces adverse events associated with endoscopic submucosal dissection (ESD). We aimed to assess the closure time (CT), technical success, and cost-effectiveness between a novel through-the-scope helix ...

    Abstract Background and aims: Mucosal closure adds time but reduces adverse events associated with endoscopic submucosal dissection (ESD). We aimed to assess the closure time (CT), technical success, and cost-effectiveness between a novel through-the-scope helix tack suture system (TTSS) and the over-the-scope suturing system (OTSS).
    Methods: In this single-center, prospective, randomized trial, all patients undergoing ESD with anticipated closure were randomized 1:1 to TTSS (study group) or OTSS (control group). Primary outcomes were CT and overall CT (OCT; CT + setup time). Secondary outcomes were rates of technical success, adverse events, and cost-effectiveness.
    Results: Forty patients were randomized to OTSS (n = 20) or TTSS (n = 20). OTSS and TTSS groups were similar with respect to age, gender, proportion of colorectal polyps, proximal colon polyps, and mean size of the resected specimen (40.9 mm vs 40.4 mm). The mean CT was 18.4 minutes for OTSS and 23.3 minutes for TTSS (P = .36). The mean OCT was 32 minutes for OTSS and 39.5 minutes for TTSS (P = .36). Closure with a primary device was successful in 17 cases (85%) with OTSS and 18 cases (90%) with TTSS (P = .63). No closure-related intraprocedural adverse events or delayed perforations were noted. Mean cost of closure was significantly lower in the TTSS group for lesions <35 mm (P = .008).
    Conclusions: TTSS was not found to be superior to OTSS with respect to CT and technical and clinical success for closure of gastric and colorectal ESD defects. TTSS is more cost-effective for closure of lesions <35 mm. (Clinical trial registration number: NCT04925271.).
    MeSH term(s) Humans ; Endoscopic Mucosal Resection/methods ; Prospective Studies ; Stomach ; Colorectal Neoplasms/surgery ; Colorectal Neoplasms/etiology ; Sutures ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Randomized Controlled Trial ; Video-Audio Media ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.07.046
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  8. Book: Coronary artery disease

    Willerson, James T. / Holmes, David R.

    (Cardiovascular medicine)

    2015  

    Author's details James T. Willerson ; David R. Holmes ed
    Series title Cardiovascular medicine
    Keywords Coronary heart disease
    Subject code 616.123
    Language English
    Size XIV, 783 S. : Ill., graph. Darst., 28 cm
    Publisher Springer
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018603220
    ISBN 978-1-4471-2827-4 ; 1-4471-2827-3
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2015 A 1374 available for loan (reading room) Lesesaal EG

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  9. Article ; Online: Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/SUO GUIDELINE (2017; Amended 2020, 2024).

    Holzbeierlein, Jeffrey / Bixler, Brooke R / Buckley, David I / Chang, Sam S / Holmes, Rebecca S / James, Andrew C / Kirkby, Erin / McKiernan, James M / Schuckman, Anne

    The Journal of urology

    2024  , Page(s) 101097JU0000000000003981

    Abstract: Purpose: Although representing approximately 25% of patients diagnosed with bladder cancer, muscle-invasive bladder cancer (MIBC) carries a significant risk of death that has not significantly changed in decades. Increasingly, clinicians and patients ... ...

    Abstract Purpose: Although representing approximately 25% of patients diagnosed with bladder cancer, muscle-invasive bladder cancer (MIBC) carries a significant risk of death that has not significantly changed in decades. Increasingly, clinicians and patients recognize the importance of multidisciplinary collaborative efforts that take into account survival and quality of life concerns. This guideline provides a risk-stratified, clinical framework for the management of muscle-invasive urothelial bladder cancer.
    Methodology/methods: In 2024, the MIBC guideline was updated through the AUA amendment process in which newly published literature is reviewed and integrated into previously published guidelines in an effort to maintain currency. The amendment allowed for the incorporation of additional literature released since the previous 2020 amendment. The updated search gathered literature from May 2020 to November 2023. This review identified 3739 abstracts, of which 46 met inclusion criteria.When sufficient evidence existed, the body of evidence was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong, Moderate, or Conditional Recommendations. In the absence of sufficient evidence, additional information is provided as Clinical Principles and Expert Opinions.
    Results: Updates were made regarding neoadjuvant/adjuvant chemotherapy, radical cystectomy, pelvic lymphadenectomy, multi-modal bladder preserving therapy, and future directions. Further revisions were made to the methodology and reference sections as appropriate.
    Conclusions: This guideline seeks to improve clinicians' ability to evaluate and treat patients with MIBC based on currently available evidence. Future studies will be essential to further support or refine these statements to improve patient care.
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003981
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  10. Article ; Online: Multi-modal fusion model for predicting adverse cardiovascular outcome post percutaneous coronary intervention.

    Bhattacharya, Amartya / Sadasivuni, Sudarsan / Chao, Chieh-Ju / Agasthi, Pradyumna / Ayoub, Chadi / Holmes, David R / Arsanjani, Reza / Sanyal, Arindam / Banerjee, Imon

    Physiological measurement

    2022  Volume 43, Issue 12

    Abstract: Background. ...

    Abstract Background.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Female ; Percutaneous Coronary Intervention/adverse effects ; Retrospective Studies ; Heart Failure ; Machine Learning ; Electrocardiography
    Language English
    Publishing date 2022-12-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1149545-5
    ISSN 1361-6579 ; 0967-3334
    ISSN (online) 1361-6579
    ISSN 0967-3334
    DOI 10.1088/1361-6579/ac9e8a
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