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Article: A Single-System Ectopic Ureter in a Child: A Challenge for Early Diagnosis.

Reinig, Barbara A / Silva, Bianca M / Fernandes, Marilyse / Onofre, Ana Luiza / Veruska Paiva Ortolan, Erika

2024 Volume 16, Issue 1, Page(s) e51834

Abstract: An ectopic ureter is an uncommon anomaly, usually associated with a duplicated urinary system. Up to 20% of ectopic ureters occur in a single system. In females, only 25% of ectopic ureters insert into the vagina and usually cause urinary incontinence, ... ...

Abstract	An ectopic ureter is an uncommon anomaly, usually associated with a duplicated urinary system. Up to 20% of ectopic ureters occur in a single system. In females, only 25% of ectopic ureters insert into the vagina and usually cause urinary incontinence, which can be confused with vaginal discharge. The diagnostic investigation includes urinary tract ultrasound, DMSA, and urethrocystography, which evaluate renal morphology and function, determining factors for surgical treatment decision that aims to preserve renal function, prevent the recurrence of infections, and reestablish urinary continence. The rarity of this anomaly and the delay in recognizing symptoms are factors related to late diagnosis.
Language	English
Publishing date	2024-01-08
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.51834
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Modified Posterior Transdural Approach for Calcified Thoracic Midline Disc Herniations: Case Report and Illustrative 2-D Video.

de Almeida, Rômulo A A / da Silva, Paulo G S / Wanderley, Bianca G / Ghizoni, Enrico / Joaquim, Andrei F

Neurology India

2024 Volume 71, Issue 6, Page(s) 1146–1149

MeSH term(s)	Humans ; Intervertebral Disc Displacement/diagnostic imaging ; Intervertebral Disc Displacement/surgery ; Diskectomy ; Thoracic Vertebrae/diagnostic imaging ; Thoracic Vertebrae/surgery
Language	English
Publishing date	2024-01-04
Publishing country	India
Document type	Case Reports ; Journal Article ; Video-Audio Media
ZDB-ID	415522-1
ISSN	1998-4022 ; 0028-3886
ISSN (online)	1998-4022
ISSN	0028-3886
DOI	10.4103/0028-3886.391376
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 698: Show issues

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Article ; Online: The Early Childhood Oral Health Impact Scale (ECOHIS): psychometric properties and application on preschoolers.

Silva, Bianca Núbia Souza / Campos, Lucas A / Marôco, João / Campos, Juliana A D B

PeerJ

2023 Volume 11, Page(s) e16035

Abstract: Background: The concept of oral health related to quality of life involves the impact that oral health has on an individual's well-being. The Early Childhood Oral Health Impact Scale (ECOHIS) was developed to measure the impact of oral health problems ... ...

Abstract	Background: The concept of oral health related to quality of life involves the impact that oral health has on an individual's well-being. The Early Childhood Oral Health Impact Scale (ECOHIS) was developed to measure the impact of oral health problems on the lives of children and their families. Objective: To evaluate the psychometric properties of ECOHIS applied to mothers of preschool children and estimate the influence of demographic characteristics, caries experience, and plaque index on the ECOHIS score. Methods: The fit of ECOHIS to the data was assessed by confirmatory analysis. Chi-square for degrees of freedom ratio ( Results: A total of 371 children participated in the study. Mothers' mean age was 33.0 (SD = 7.04) years. The ECOHIS presented a good fit to the data ( Conclusion: The data obtained with the ECOHIS were valid, reliable, and invariant. Children with caries experience and from lower income families had a greater impact of oral problems.
MeSH term(s)	Female ; Humans ; Child, Preschool ; Adult ; Quality of Life ; Oral Health ; Psychometrics ; Reproducibility of Results ; Surveys and Questionnaires
Language	English
Publishing date	2023-10-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.16035
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Article ; Online: Alkylation of 6-thiopurine derivatives by the Mitsunobu reaction.

do Espírito Santo, Rafael Dias / da Silva, Bianca Nascimento Monteiro / Rabi, Jaime A / Pinho, Vagner D

Nucleosides, nucleotides & nucleic acids

2023 Volume 42, Issue 7, Page(s) 516–526

Abstract: Alkylation of thiopurine derivatives with alcohols by the Mitsunobu reaction are reported in moderated to good yields. The method was applied in synthesis of number of thiopurine and thiopurine ribosides derivatives. ...

Abstract	Alkylation of thiopurine derivatives with alcohols by the Mitsunobu reaction are reported in moderated to good yields. The method was applied in synthesis of number of thiopurine and thiopurine ribosides derivatives.
MeSH term(s)	Mercaptopurine ; Alcohols ; Alkylation ; Magnetic Resonance Spectroscopy
Chemical Substances	Mercaptopurine (E7WED276I5) ; Alcohols
Language	English
Publishing date	2023-01-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2008956-9
ISSN	1532-2335 ; 1525-7770
ISSN (online)	1532-2335
ISSN	1525-7770
DOI	10.1080/15257770.2022.2163501
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Article ; Online: Per- and polyfluoroalkyl substances (PFAS) in sediments collected from the Pensacola Bay System watershed.

Ahmadireskety, Atiye / Da Silva, Bianca F / Awkerman, Jill A / Aufmuth, Joe / Yost, Richard A / Bowden, John A

Environmental advances

2023 Volume 5, Page(s) 1–8

Abstract: Sediment samples from 25 locations in the Pensacola Bay System (PBS) watershed were analyzed for the presence of 51 per- and polyfluoroalkyl substances (PFAS) using ultra high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) and ... ...

Abstract	Sediment samples from 25 locations in the Pensacola Bay System (PBS) watershed were analyzed for the presence of 51 per- and polyfluoroalkyl substances (PFAS) using ultra high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) and selected reaction monitoring. Results revealed quantifiable concentrations of PFAS in all sampling locations. More specifically, perfluorobutanoic acid (PFBA) was present in every sediment sample with a minimum and maximum concentration of 0.04 to 0.48 ng g
Language	English
Publishing date	2023-12-29
Publishing country	England
Document type	Journal Article
ISSN	2666-7657
ISSN (online)	2666-7657
DOI	10.1016/j.envadv.2021.100088
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Article ; Online: The Early Childhood Oral Health Impact Scale (ECOHIS)

Bianca Núbia Souza Silva / Lucas A. Campos / João Marôco / Juliana A.D.B Campos

PeerJ, Vol 11, p e

psychometric properties and application on preschoolers

2023 Volume 16035

Abstract: Background The concept of oral health related to quality of life involves the impact that oral health has on an individual’s well-being. The Early Childhood Oral Health Impact Scale (ECOHIS) was developed to measure the impact of oral health problems on ... ...

Abstract	Background The concept of oral health related to quality of life involves the impact that oral health has on an individual’s well-being. The Early Childhood Oral Health Impact Scale (ECOHIS) was developed to measure the impact of oral health problems on the lives of children and their families. Objective To evaluate the psychometric properties of ECOHIS applied to mothers of preschool children and estimate the influence of demographic characteristics, caries experience, and plaque index on the ECOHIS score. Methods The fit of ECOHIS to the data was assessed by confirmatory analysis. Chi-square for degrees of freedom ratio (χ2/df), Comparative Fit Index (CFI), Tucker-Lewis Index (TLI), and Root Mean Square Error of Approximation (RMSEA) were used. Reliability was estimated by the ordinal coefficients alpha (α) and omega (ω). The factorial invariance was estimated by the difference in CFI (ΔCFI). Comparisons of the ECOHIS mean scores according to the demographic characteristics, caries experience, and plaque index was performed using analysis of variance (ANOVA). Results A total of 371 children participated in the study. Mothers’ mean age was 33.0 (SD = 7.04) years. The ECOHIS presented a good fit to the data (χ2/df = 4.31; CFI = 0.95; TLI = 0.94; RMSEA = 0.09) and a strict model invariance. Children without caries and from higher income class had lower oral health impact. Conclusion The data obtained with the ECOHIS were valid, reliable, and invariant. Children with caries experience and from lower income families had a greater impact of oral problems.
Keywords	Oral health ; Children ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	360
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Melatonin improves the viability and ultrastructure of bovine oocyte-granulosa complexes of in vitro cultured early antral follicles.

Silva, Bianca R / Nascimento, Danisvânia R / Costa, Francisco C / Azevedo, Antônia V / Paulino, Laís R F M / Aguiar, Francisco L N / Batista, Ana L P S / Donato, Mariana A M / Silva, José R V

Reproduction in domestic animals = Zuchthygiene

2024 Volume 59, Issue 3, Page(s) e14543

Abstract: This study aims to investigate the effects of melatonin on follicular growth, viability and ultrastructure, as well as on the levels of mRNA for antioxidant enzymes, reactive oxygen species (ROS) and meiotic progression in oocytes from in vitro cultured ... ...

Abstract	This study aims to investigate the effects of melatonin on follicular growth, viability and ultrastructure, as well as on the levels of mRNA for antioxidant enzymes, reactive oxygen species (ROS) and meiotic progression in oocytes from in vitro cultured bovine early antral follicles. To this end, isolated early antral follicles (500-600 μm) were cultured in TCM-199
MeSH term(s)	Female ; Animals ; Cattle ; Melatonin/pharmacology ; Melatonin/metabolism ; Reactive Oxygen Species/metabolism ; Oocytes ; Superoxide Dismutase ; RNA, Messenger/metabolism ; Fluoresceins
Chemical Substances	calcein AM (148504-34-1) ; Melatonin (JL5DK93RCL) ; Reactive Oxygen Species ; Superoxide Dismutase (EC 1.15.1.1) ; RNA, Messenger ; Fluoresceins
Language	English
Publishing date	2024-03-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1015187-4
ISSN	1439-0531 ; 0936-6768
ISSN (online)	1439-0531
ISSN	0936-6768
DOI	10.1111/rda.14543
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Article ; Online: Face your fears: attenuating remote fear memories by reconsolidation-updating.

Silva, Bianca A / Gräff, Johannes

Trends in cognitive sciences

2023 Volume 27, Issue 4, Page(s) 404–416

Abstract: Traumatic events generate some of the most enduring memories, yet little is known about how long-lasting fear memories can be attenuated. In this review, we collect the surprisingly sparse evidence on remote fear memory attenuation from both animal and ... ...

Abstract	Traumatic events generate some of the most enduring memories, yet little is known about how long-lasting fear memories can be attenuated. In this review, we collect the surprisingly sparse evidence on remote fear memory attenuation from both animal and human research. What is becoming apparent is twofold: although remote fear memories are more resistant to change compared with recent ones, they can nevertheless be attenuated when interventions are targeted toward the period of memory malleability instigated by memory recall, the reconsolidation window. We describe the physiological mechanisms underlying remote reconsolidation-updating approaches and highlight how they can be enhanced through interventions promoting synaptic plasticity. By capitalizing on an intrinsically relevant phase of memory, reconsolidation-updating harbors the potential to permanently alter remote fear memories.
MeSH term(s)	Animals ; Humans ; Memory, Long-Term ; Memory/physiology ; Fear/physiology ; Neuronal Plasticity ; Extinction, Psychological/physiology
Language	English
Publishing date	2023-02-20
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2010989-1
ISSN	1879-307X ; 1364-6613
ISSN (online)	1879-307X
ISSN	1364-6613
DOI	10.1016/j.tics.2023.01.004
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Article ; Online: The Risk of Reinfection or Primary Hepatitis E Virus Infection at a Liver Transplant Center in Brazil: An Observational Cohort Study.

Zicker, Michelle / Pinho, João R R / Welter, Eliane A R / Guardia, Bianca D / da Silva, Paulo G T M / da Silveira, Leonardo B / Camargo, Luís F A

Viruses

2024 Volume 16, Issue 2

Abstract: The hepatitis E virus is a major etiological agent of chronic hepatitis in immunosuppressed individuals. Seroprevalence in the liver transplantation setting varies according to the seroprevalence of the general population in different countries. This was ...

Abstract	The hepatitis E virus is a major etiological agent of chronic hepatitis in immunosuppressed individuals. Seroprevalence in the liver transplantation setting varies according to the seroprevalence of the general population in different countries. This was a prospective cohort study of liver transplant recipients in southeastern Brazil. Recipients were systematically followed for one year, with the objective of determining the prevalence, incidence, and natural history of HEV infection in this population. We included 107 liver transplant recipients and 83 deceased donors. Positivity for anti-HEV IgG was detected in 10.2% of the recipients and in 9.7% of the donors. None of the patients tested positive for HEV RNA at baseline or during follow-up. There were no episodes of reactivation or seroconversion, even in cases of serological donor-recipient mismatch or in recipients with acute hepatitis. Acute and chronic HEV infections seem to be rare events in the region studied. That could be attributable to social, economic, and environmental factors. Our data indicate that, among liver transplant recipients, hepatitis E should be investigated only when there are elevated levels of transaminases with no defined cause, as part of the differential diagnosis of seronegative hepatitis after transplantation.
MeSH term(s)	Humans ; Hepatitis E virus/genetics ; Hepatitis E ; Liver Transplantation/adverse effects ; Prospective Studies ; Brazil/epidemiology ; Seroepidemiologic Studies ; Reinfection ; RNA, Viral/genetics ; Cohort Studies ; Hepatitis Antibodies ; Persistent Infection
Chemical Substances	RNA, Viral ; Hepatitis Antibodies
Language	English
Publishing date	2024-02-16
Publishing country	Switzerland
Document type	Observational Study ; Journal Article
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v16020301
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Article ; Online: Antimicrobial consumption and drug utilization patterns among COVID-19 and non-COVID-19 patients.

Antunes, Bianca B P / Silva, Amanda A B / Nunes, Patricia H C / Martin-Loeches, Ignacio / Kurtz, Pedro / Hamacher, Silvio / Bozza, Fernando A

The Journal of antimicrobial chemotherapy

2023 Volume 78, Issue 3, Page(s) 840–849

Abstract: Objectives: To understand differences in antimicrobial use between COVID-19 and non-COVID-19 patients. To compare two metrics commonly used for antimicrobial use: Defined Daily Dose (DDD) and Days of Therapy (DOT). To analyse the order in which ... ...

Abstract	Objectives: To understand differences in antimicrobial use between COVID-19 and non-COVID-19 patients. To compare two metrics commonly used for antimicrobial use: Defined Daily Dose (DDD) and Days of Therapy (DOT). To analyse the order in which antimicrobials were prescribed to COVID-19 patients using process mining techniques. Methods: We analysed data regarding all ICU admissions from 1 January 2018 to 14 September 2020, in 17 Brazilian hospitals. Our main outcome was the antimicrobial use estimated by the DDD and DOT (Days of Therapy). We compared clinical characteristics and antimicrobial consumption between COVID-19 and non-COVID-19 patients. We used process mining to evaluate the order in which the antimicrobial schemes were prescribed to each COVID-19 patient. Results: We analysed 68 405 patients admitted before the pandemic, 12 319 non-COVID-19 patients and 3240 COVID-19 patients. Comparing those admitted during the pandemic, the COVID-19 patients required advanced respiratory support more often (42% versus 12%). They also had longer ICU length of stay (6 versus 3 days), higher ICU mortality (18% versus 5.4%) and greater use of antimicrobials (70% versus 39%). Most of the COVID-19 treatments started with penicillins with ß-lactamase inhibitors (30%), third-generation cephalosporins (22%), or macrolides in combination with penicillins (19%). Conclusions: Antimicrobial prescription increased in Brazilian ICUs during the COVID-19 pandemic, especially during the first months of the epidemic. We identified greater use of broad-spectrum antimicrobials by COVID-19 patients. Overall, the DDD metric overestimated antimicrobial use compared with the DOT metric.
MeSH term(s)	Humans ; Pandemics ; COVID-19 ; Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents/therapeutic use ; Drug Utilization ; Penicillins
Chemical Substances	Anti-Bacterial Agents ; Anti-Infective Agents ; Penicillins
Language	English
Publishing date	2023-02-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	191709-2
ISSN	1460-2091 ; 0305-7453
ISSN (online)	1460-2091
ISSN	0305-7453
DOI	10.1093/jac/dkad025
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