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  1. Article ; Online: Therapeutic plasma exchange for persistent encephalopathy associated with Covid-19.

    Ranganathan, Chakrapani / Fusinski, Shelley D / Obeid, Imad M / Ismail, Khaled M / Ferguson, Derrick T / Raminick, Mindy F / Dawes, Sean M

    eNeurologicalSci

    2021  Volume 22, Page(s) 100327

    Abstract: Patients infected with COVID-19 virus, show a highly variable symptomatology which can include central nervous system (CNS) dysfunction. One of the most disabling CNS manifestations is persistent severe encephalopathy seen for weeks after the resolution ... ...

    Abstract Patients infected with COVID-19 virus, show a highly variable symptomatology which can include central nervous system (CNS) dysfunction. One of the most disabling CNS manifestations is persistent severe encephalopathy seen for weeks after the resolution of the acute viral pneumonia and associated acute systemic illnesses. The precise pathophysiology of this persistent Post COVID Encephalopathy is unknown but may involve direct viral invasion of microvascular endothelium, microvascular thrombosis, toxic neuronal effects of inflammatory products, vasoactive pathology at arteriolar level or leptomeningeal inflammation. Currently, there are no established specific treatments for Post COVID -19 encephalopathy. We present a case series of three patients that underwent Therapeutic Plasma Exchange (TPE) with salinized albumin that suggests a positive therapeutic effect. We believe that the results warrant further evaluation for the role of TPE with a prospective randomized trial in persistent Post COVID -19 encephalopathy syndrome.
    Language English
    Publishing date 2021-02-07
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2838045-9
    ISSN 2405-6502 ; 2405-6502
    ISSN (online) 2405-6502
    ISSN 2405-6502
    DOI 10.1016/j.ensci.2021.100327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Acceptability of Mobile Phone-Based Nurse-Delivered Counseling Intervention to Improve HIV Treatment Adherence and Self-Care Behaviors Among HIV-Positive Women in India.

    Duggal, Mona / Chakrapani, Venkatesan / Liberti, Lauren / Satyanarayna, Veena / Varghese, Meiya / Singh, Pushpendera / Ranganathan, Mohini / Chandra, Prabha / Reynolds, Nancy R

    AIDS patient care and STDs

    2018  Volume 32, Issue 9, Page(s) 349–359

    Abstract: We assessed the acceptability of nurse-delivered mobile phone-based counseling to support adherence to antiretroviral treatment (ART) and self-care behaviors among HIV-positive women in India. We conducted open-ended, in-depth interviews with 27 HIV- ... ...

    Abstract We assessed the acceptability of nurse-delivered mobile phone-based counseling to support adherence to antiretroviral treatment (ART) and self-care behaviors among HIV-positive women in India. We conducted open-ended, in-depth interviews with 27 HIV-positive women and 19 key informants at a government ART center in Karnataka, India. Data were analyzed with interpretive techniques. About half of the HIV-positive women owned a mobile phone and many had access to mobile phones of their family members. Most women perceived phone-based counseling as a personalized care approach to get information on demand. Also, women felt that they could discuss mental health issues and ask sensitive information that they would hesitate to discuss face-to-face. Findings indicate that, when compared with text messaging, mobile phone-based counseling could be a more acceptable way to engage with women on ART, especially those with limited literacy. Future studies should focus on testing mobile phone-based information/counseling and adherence interventions that take the local context into account.
    MeSH term(s) Adult ; Anti-Retroviral Agents/therapeutic use ; Cell Phone ; Counseling/methods ; Female ; HIV Infections/drug therapy ; HIV Infections/psychology ; Humans ; India ; Interviews as Topic ; Middle Aged ; Patient Acceptance of Health Care ; Qualitative Research ; Self Care ; Text Messaging ; Treatment Adherence and Compliance
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2018-09-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1326868-5
    ISSN 1557-7449 ; 0893-5068 ; 1087-2914
    ISSN (online) 1557-7449
    ISSN 0893-5068 ; 1087-2914
    DOI 10.1089/apc.2017.0315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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