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  1. Book: Pulmonary hypertension reviews

    Mathai, Stephen C.

    (International journal of clinical practice : Supplement ; 179)

    2013  

    Author's details ed. by Stephen Mathai
    Series title International journal of clinical practice : Supplement ; 179
    The International journal of clinical practice
    International journal of clinical practice ; Supplement
    Collection The International journal of clinical practice
    International journal of clinical practice ; Supplement
    Language English
    Size 23 S. : graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017666131
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ua VI Zs 301 -Suppl.179- verfügbar in Königswinter Königswinter

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  2. Book: Pulmonary hypertension reviews

    Mathai, Stephen C.

    (International journal of clinical practice : Supplement ; 177)

    2012  

    Author's details [ed. by Stephen Mathai ...]
    Series title International journal of clinical practice : Supplement ; 177
    The International journal of clinical practice
    International journal of clinical practice ; Supplement
    Collection The International journal of clinical practice
    International journal of clinical practice ; Supplement
    Language English
    Size 19 S. : Ill., graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017495092
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ua VI Zs 301 -Suppl.177- verfügbar in Königswinter Königswinter

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  3. Article ; Online: Scleroderma pulmonary arterial hypertension: the same as idiopathic pulmonary arterial hypertension?

    Khan, Sarah L / Mathai, Stephen C

    Current opinion in pulmonary medicine

    2023  Volume 29, Issue 5, Page(s) 380–390

    Abstract: Purpose of review: Pulmonary arterial hypertension (PAH) is a common complication of systemic sclerosis (SSc), which confers significant morbidity and mortality. The current therapies and treatment strategies for SSc-associated PAH (SSc-PAH) are ... ...

    Abstract Purpose of review: Pulmonary arterial hypertension (PAH) is a common complication of systemic sclerosis (SSc), which confers significant morbidity and mortality. The current therapies and treatment strategies for SSc-associated PAH (SSc-PAH) are informed by those used to treat patients with idiopathic PAH (IPAH). There are, however, important differences between these two diseases that impact diagnosis, treatment, and outcomes.
    Recent findings: Both SSc-PAH and IPAH are incompletely understood with ongoing research into the underlying cellular biology that characterize and differentiate the two diseases. Additional research seeks to improve identification among SSc patients in order to diagnose patients earlier in the course of their disease. Novel therapies specifically for SSc-PAH such as rituximab and dimethyl fumarate are under investigation.
    Summary: Although patients with SSc-PAH and IPAH present with similar symptoms, there are significant differences between these two forms of PAH that warrant further investigation and characterization of optimal detection strategies, treatment algorithms, and outcomes assessment.
    MeSH term(s) Humans ; Familial Primary Pulmonary Hypertension ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/etiology ; Pulmonary Arterial Hypertension/diagnosis ; Pulmonary Arterial Hypertension/drug therapy ; Pulmonary Arterial Hypertension/etiology ; Scleroderma, Systemic/complications
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000001001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4900: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Ambitions for Pulmonary Arterial Hypertension Composite End Points: A Chain Is Only as Strong as Its Weakest Link.

    Zelt, Jason G E / Weatherald, Jason / Mathai, Stephen C

    Chest

    2023  Volume 164, Issue 6, Page(s) 1350–1353

    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.10.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 349: Show issues

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  5. Article ; Online: Pulmonary Hypertension Associated with Connective Tissue Disease.

    Mathai, Stephen C

    Cardiology clinics

    2020  Volume 40, Issue 1, Page(s) 29–43

    Abstract: Pulmonary hypertension (PH), a syndrome characterized by elevated pulmonary pressures, commonly complicates connective tissue disease (CTD) and is associated with increased morbidity and mortality. The incidence of PH varies widely between CTDs; patients ...

    Abstract Pulmonary hypertension (PH), a syndrome characterized by elevated pulmonary pressures, commonly complicates connective tissue disease (CTD) and is associated with increased morbidity and mortality. The incidence of PH varies widely between CTDs; patients with systemic sclerosis are most likely to develop PH. Several different types of PH can present in CTD, including PH related to left heart disease and respiratory disease. Importantly, CTD patients are at risk for developing pulmonary arterial hypertension, a rare form of PH that is associated with high morbidity and mortality. Future therapies targeting pulmonary vascular remodeling may improve outcomes for patients with this devastating disease.
    MeSH term(s) Connective Tissue Diseases/complications ; Connective Tissue Diseases/epidemiology ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/epidemiology ; Hypertension, Pulmonary/etiology
    Language English
    Publishing date 2020-11-01
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1196385-2
    ISSN 1558-2264 ; 0733-8651
    ISSN (online) 1558-2264
    ISSN 0733-8651
    DOI 10.1016/j.ccl.2021.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Genetic Testing in Pulmonary Arterial Hypertension Evaluation: A Patient and Clinician Survey.

    Rice, Jordin L / Austin, Eric D / Mathai, Stephen C / Sahay, Sandeep

    Chest

    2023  

    Language English
    Publishing date 2023-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.11.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 349: Show issues

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  7. Article ; Online: Performance Under Pressure: The Relevance of Pulmonary Vascular Response to Exercise Challenge in Scleroderma.

    Ulrich, Silvia / Mathai, Stephen C

    Chest

    2021  Volume 159, Issue 2, Page(s) 481–483

    MeSH term(s) Exercise ; Humans ; Hypertension, Pulmonary
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 349: Show issues

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  8. Article ; Online: Precision medicine in pulmonary hypertension: Start with the end (point).

    Mathai, Stephen C

    International journal of cardiology

    2018  Volume 257, Page(s) 339–340

    MeSH term(s) Humans ; Hypertension, Pulmonary ; Magnetic Resonance Imaging ; Precision Medicine ; Ventricular Function, Right
    Language English
    Publishing date 2018--15
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2018.01.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Exercise Echocardiography as a Screening Tool in Systemic Sclerosis.

    Mukherjee, Monica / Mathai, Stephen C

    The Journal of rheumatology

    2020  Volume 47, Issue 5, Page(s) 643–645

    MeSH term(s) Cohort Studies ; Echocardiography ; Humans ; Hypertension, Pulmonary ; Scleroderma, Systemic
    Language English
    Publishing date 2020-05-01
    Publishing country Canada
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.191249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1168: Show issues Location:
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    Zs.MO 135: Show issues

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  10. Article ; Online: Assessing the Psychometric Validity of the Epistaxis Severity Score: Internal Consistency and Test-Retest Reliability.

    Gong, Anna J / Bolsegui, Marisabel Linares / Lee, Emerson E / Mathai, Stephen C / Weiss, Clifford R

    American journal of rhinology & allergy

    2023  Volume 38, Issue 1, Page(s) 38–46

    Abstract: Background: The Epistaxis Severity Score (ESS) is the gold-standard patient-reported outcome measure for evaluating nosebleed severity in patients with hereditary hemorrhagic telangiectasia (HHT). To date, the ESS has been assessed only for content ... ...

    Abstract Background: The Epistaxis Severity Score (ESS) is the gold-standard patient-reported outcome measure for evaluating nosebleed severity in patients with hereditary hemorrhagic telangiectasia (HHT). To date, the ESS has been assessed only for content validity and concurrent validity.
    Objective: We evaluate the internal consistency and test-retest reliability of the ESS.
    Materials and methods: After receiving institutional review board approval, we sent an online survey battery, including the ESS survey, to 305 (39% male) English-speaking HHT patients ≥18 years old at a single center. Of those, 140 (46%) patients completed the battery, and 110/140 (79%) reported epistaxis. Cronbach's alpha and correlation analyses were used to evaluate internal consistency. For the test-retest reliability evaluation, we recruited 69 HHT patients during HHT clinic to complete 2 self-administered ESS surveys 2 weeks apart. Participants also completed a modified Clinical Global Impression-Improvement scale with readministration of the ESS survey. We calculated the intraclass correlation coefficient in a 2-way mixed model with absolute agreement.
    Results: The ESS survey demonstrated low internal consistency (Cronbach's alpha = 0.495), suggesting that it measured multiple unrelated concepts. Factor analysis revealed 3 latent factors with moderate intercorrelation, suggesting the presence of 3 related but distinct constructs underlying the ESS. However, the ESS demonstrated excellent test-retest reliability (intraclass correlation coefficient = 0.955; 95% CI, 0.91-0.98).
    Conclusion: Although the ESS demonstrates high test-retest reliability, it may not adequately assess different dimensions of nosebleed severity. Additional correlated survey questions and sub-scores may be needed to increase internal consistency to accurately measure each component of epistaxis severity. It is necessary to acknowledge epistaxis severity from different dimensions and to consider evaluating individual ESS items separately for a comprehensive understanding.
    MeSH term(s) Humans ; Male ; Adolescent ; Female ; Epistaxis/diagnosis ; Reproducibility of Results ; Psychometrics ; Telangiectasia, Hereditary Hemorrhagic/diagnosis ; Surveys and Questionnaires
    Language English
    Publishing date 2023-10-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/19458924231207137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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