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Book ; Online: Implementation of WHO guidelines on management of severe malnutrition in hospitals in Africa / Jacqueline L. Deen . [et al.] ; Mise en oeuvre des directives OMS sur la prise en charge hospitalière de la malnutrition sévère en Afrique

Deen, Jacqueline L / Funk, Matthias / Guevara, Victor C / Saloojee, Haroon / Doe, James, Y / Palmer, Ayo / Weber, Martin W

résumé ; Aplicación de las directrices de la OMS sobre elmanejo de la malnutrición grave en hopitales de Africa : resumen

2003

Abstract: Summaries in English, French and ... ...

Abstract	Summaries in English, French and Spanish
Keywords	Child nutrition disorders ; Infant nutrition disorders ; Hypothermia ; Hypoglycemia ; Fluid therapy ; Diet therapy ; Hospitals ; World Health Organization ; Practice guidelines ; Guideline adherence ; Africa ; Nutrition and Food Safety ; therapy
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Article ; Online: Implementation of WHO guidelines on management of severe malnutrition in hospitals in Africa / Jacqueline L. Deen . [et al.] ; Mise en oeuvre des directives OMS sur la prise en charge hospitalière de la malnutrition sévère en Afrique

Deen, Jacqueline L / Funk, Matthias / Guevara, Victor C / Saloojee, Haroon / Doe, James, Y / Palmer, Ayo / Weber, Martin W

résumé ; Aplicación de las directrices de la OMS sobre elmanejo de la malnutrición grave en hopitales de Africa : resumen

2003

Abstract: Summaries in English, French and ... ...

Abstract	Summaries in English, French and Spanish
Keywords	Child Nutrition Disorders ; Infant Nutrition Disorders ; Hypothermia ; Hypoglycemia ; Fluid Therapy ; Diet Therapy ; Hospitals ; World Health Organization ; Practice Guideline ; Guideline Adherence ; Africa ; Nutrition and Food Safety ; therapy
Document type	Book ; Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preventing cholera outbreaks through early targeted interventions.

von Seidlein, Lorenz / Deen, Jacqueline L

PLoS medicine

2018 Volume 15, Issue 2, Page(s) e1002510

Abstract: In a Perspective, Lorenz von Seidlein and Jacqueline L. Deen discuss the implications of Andrew ...

Abstract	In a Perspective, Lorenz von Seidlein and Jacqueline L. Deen discuss the implications of Andrew Azman and colleagues' accompanying study for management of cholera outbreaks.
MeSH term(s)	Cholera/epidemiology ; Cholera/prevention & control ; Cholera Vaccines/therapeutic use ; Disease Outbreaks/prevention & control ; Early Medical Intervention/methods ; Health Plan Implementation/organization & administration ; Health Plan Implementation/standards ; Health Services Needs and Demand/organization & administration ; Health Services Needs and Demand/standards ; Humans ; Preventive Medicine/methods ; Preventive Medicine/organization & administration ; Public Health Administration/methods ; Public Health Administration/standards
Chemical Substances	Cholera Vaccines
Language	English
Publishing date	2018-02-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2185925-5
ISSN	1549-1676 ; 1549-1277
ISSN (online)	1549-1676
ISSN	1549-1277
DOI	10.1371/journal.pmed.1002510
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Article ; Online: Preventing cholera outbreaks through early targeted interventions.

Lorenz von Seidlein / Jacqueline L Deen

PLoS Medicine, Vol 15, Iss 2, p e

2018 Volume 1002510

Abstract: In a Perspective, Lorenz von Seidlein and Jacqueline L. Deen discuss the implications of Andrew ...

Abstract	In a Perspective, Lorenz von Seidlein and Jacqueline L. Deen discuss the implications of Andrew Azman and colleagues' accompanying study for management of cholera outbreaks.
Keywords	Medicine ; R
Language	English
Publishing date	2018-02-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Paracetamol for dengue fever: no benefit and potential harm?

Deen, Jacqueline / von Seidlein, Lorenz

The Lancet. Global health

2019 Volume 7, Issue 5, Page(s) e552–e553

MeSH term(s)	Acetaminophen ; Adult ; Antipyretics ; Dengue ; Fever ; Humans ; Liver
Chemical Substances	Antipyretics ; Acetaminophen (362O9ITL9D)
Language	English
Publishing date	2019-04-16
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	2723488-5
ISSN	2214-109X ; 2214-109X
ISSN (online)	2214-109X
ISSN	2214-109X
DOI	10.1016/S2214-109X(19)30157-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis.

Deen, Jacqueline / Mukaka, Mavuto / von Seidlein, Lorenz

Malaria journal

2021 Volume 20, Issue 1, Page(s) 131

Abstract: Background: Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria ... ...

Abstract	Background: Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria cases among potential contacts who were screened, was assessed. Methods: A literature search was conducted on PubMed to identify studies on reactive case detection in the Greater Mekong Sub-region. Eligible published articles were reviewed and pooled estimates from the studies were calculated, by type of malaria test used. Results: Eighty-five publications were retrieved, of which 8 (9.4%) eligible articles were included in the analysis. The yield from reactive case detection ranged from 0.1 to 4.2%, with higher rates from PCR testing compared with microscopy and/or rapid diagnostic test. The overall yield from microscopy and/or rapid diagnostic test was 0.56% (95% CI 0.31-0.88%), while that from PCR was 2.35% (95% CI 1.19-3.87%). The two studies comparing different target groups showed higher yield from co-workers/co-travellers, compared with household contacts. Conclusion: In low malaria transmission settings, the effectiveness of reactive case detection is diminishing. In the Greater Mekong Sub-region, modifying reactive case detection from household contacts to co-workers/co-travellers and from testing to presumptive treatment of targeted contacts, could increase the impact of this approach.
MeSH term(s)	Asia, Southeastern ; Diagnostic Tests, Routine/statistics & numerical data ; Humans ; Malaria/diagnosis ; Mass Screening/statistics & numerical data ; Microscopy/statistics & numerical data ; Polymerase Chain Reaction/statistics & numerical data
Language	English
Publishing date	2021-03-04
Publishing country	England
Document type	Comparative Study ; Journal Article ; Meta-Analysis ; Systematic Review
ISSN	1475-2875
ISSN (online)	1475-2875
DOI	10.1186/s12936-021-03667-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The case for ring vaccinations with special consideration of oral cholera vaccines.

Deen, Jacqueline / von Seidlein, Lorenz

Human vaccines & immunotherapeutics

2018 Volume 14, Issue 8, Page(s) 2069–2074

Abstract: Ring vaccinations create a zone of immune contacts around a case to prevent further disease transmission and have been successfully employed in the eradication of smallpox and the control of other infections. Millions of oral cholera vaccine (OCV) doses ... ...

Abstract	Ring vaccinations create a zone of immune contacts around a case to prevent further disease transmission and have been successfully employed in the eradication of smallpox and the control of other infections. Millions of oral cholera vaccine (OCV) doses have been effectively deployed through mass vaccination campaigns. But there are situations when the OCV supply, resources, and time are limited and alternative strategies need to be considered. People living in close proximity of cholera cases often share risk factors such as contaminated water supply and poor sanitation. Targeting people within a given radius around a cholera case for intervention including vaccination, improved water supply and sanitation may be a practical and effective approach. A ring oral cholera vaccination strategy could be considered before, after or as an alternative to a mass vaccination approach. We review here the use of the ring vaccinations in general and specifically during cholera outbreaks.
MeSH term(s)	Administration, Oral ; Cholera/epidemiology ; Cholera/prevention & control ; Cholera/transmission ; Cholera Vaccines/administration & dosage ; Disease Outbreaks/prevention & control ; Endemic Diseases/prevention & control ; Humans ; Risk Factors ; Vaccination/methods ; Water Microbiology ; Water Supply
Chemical Substances	Cholera Vaccines
Language	English
Publishing date	2018-05-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2018.1462068
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Article: Calcinosis Cutis Associated with Chronic Sclerodermoid Graft versus Host Disease: A Case and Review of the Literature.

Deen, Jacqueline / Byrom, Lisa / Robertson, Ivan

Case reports in dermatological medicine

2020 Volume 2020, Page(s) 9250923

Abstract: We present a rare case of calcinosis cutis associated with chronic sclerodermoid graft versus host disease in a 59-year-old male, 13 years following allogenic bone marrow transplantation. The etiology of calcification was thought to be dystrophic. ... ...

Abstract	We present a rare case of calcinosis cutis associated with chronic sclerodermoid graft versus host disease in a 59-year-old male, 13 years following allogenic bone marrow transplantation. The etiology of calcification was thought to be dystrophic. Further research is needed to understand the link between calcinosis cutis and chronic sclerodermoid graft versus host disease to assist with selecting appropriate management for these patients.
Language	English
Publishing date	2020-02-27
Publishing country	United States
Document type	Case Reports
ZDB-ID	2684644-5
ISSN	2090-6471 ; 2090-6463
ISSN (online)	2090-6471
ISSN	2090-6463
DOI	10.1155/2020/9250923
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Article: High transmission of endemic human coronaviruses before and during the COVID-19 pandemic in adolescents in Cebu, Philippines.

Joseph, Janet O / Ylade, Michelle / Daag, Jedas Veronica / Aogo, Rosemary / Crisostomo, Maria Vinna / Mpingabo, Patrick / Premkumar, Lakshmanane / Deen, Jacqueline / Katzelnick, Leah

Research square

2023

Abstract: Background: SARS-CoV-2, the causative agent of COVID-19, is a betacoronavirus belonging to the same genus as endemic human coronaviruses (hCoVs) OC43 and HKU1 and is distinct from alpha hCoVs 229E and NL63. In a study of adolescents in the Philippines, ... ...

Abstract	Background: SARS-CoV-2, the causative agent of COVID-19, is a betacoronavirus belonging to the same genus as endemic human coronaviruses (hCoVs) OC43 and HKU1 and is distinct from alpha hCoVs 229E and NL63. In a study of adolescents in the Philippines, we evaluated the seroprevalence to hCoVs, whether pre-pandemic hCoV immunity modulated subsequent risk of SARS-CoV-2 infection, and if SARS-CoV-2 infection affected the transmission of the hCoVs. Methods: From 499 samples collected in 2021 and screened by SARS-CoV-2 receptor binding domain (RBD) enzyme-linked immunosorbent assay (ELISA), we randomly selected 59 SARS-CoV-2 negative and 61 positive individuals for further serological evaluation. We measured RBD and spike antibodies to the four hCoVs and SARS-CoV-2 by ELISA in samples from the same participants collected pre-pandemic (2018-2019) and mid-pandemic (2021), before COVID-19 vaccination. Results: We observed over 72% seropositivity to the four hCoVs pre-pandemic. Binding antibodies increased with age to 229E and OC43, suggesting endemic circulation, while immunity was flat across ages for HKU1 and NL63. During the COVID-19 pandemic, antibody level increased significantly to the RBDs of OC43, NL63, and 229E and spikes of all four hCoVs in both SARS-CoV-2 negative and positive adolescents. Those aged 12-15 years old in 2021 had higher antibodies to RBD and spike of OC43, NL63, and 229E than adolescents the same age in 2019, further demonstrating intense transmission of the hCoVs during the pandemic. Conclusions: We observe a limited impact of the COVID-19 pandemic on endemic hCoV transmission. This study provides insight into co-circulation of hCoVs and SARS-CoV-2.
Language	English
Publishing date	2023-11-16
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-3581033/v1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Crowding has consequences: Prevention and management of COVID-19 in informal urban settlements.

von Seidlein, Lorenz / Alabaster, Graham / Deen, Jacqueline / Knudsen, Jakob

Building and environment

2020 Volume 188, Page(s) 107472

Abstract: COVID-19 spreads via aerosols, droplets, fomites and faeces. The built environment that facilitates crowding increases exposure and hence transmission of COVID-19 as evidenced by outbreaks in both cool-dry and hot-humid climates, such as in the US prison ...

Abstract	COVID-19 spreads via aerosols, droplets, fomites and faeces. The built environment that facilitates crowding increases exposure and hence transmission of COVID-19 as evidenced by outbreaks in both cool-dry and hot-humid climates, such as in the US prison system and dormitories in Singapore, respectively. This paper explores how the built environment influences crowding and COVID-19 transmission, focusing on informal urban settlements (slums). We propose policy and practice changes that could reduce COVID-19 transmission. There are several issues on how COVID-19 affects informal urban settlements. Slum populations tend to be younger than the overall population. Lower numbers of older people lessen the morbidity and mortality of the pandemic in slum areas. Second, many slum populations are highly mobile. By returning to their ancestral villages residents can avoid the risks of overcrowding and reduce the population density in a given area but may spread COVID-19 to other areas. Third, detection and registration of COVID-19 cases depends on patients presenting to health care providers. If the risk of visiting a health care centre outweighs the potential benefits patients may prefer not to seek treatment. The control and prevention of COVID-19 in informal urban settlements starts with organizing community infrastructure for diagnosis and treatment and assuring that basic needs (food, water, sanitation, health care and public transport) are met during quarantine. Next, community members at highest risk need to be identified and protected. Low-income, informal settlements need to be recognized as a reservoir and source for persistent transmission. Solutions to overcrowding must be developed for this and future pandemics. In view of the constant risk that slums present to the entire population decisive steps need to be taken to rehabilitate and improve informal settlements, while avoiding stigmatization.
Language	English
Publishing date	2020-11-22
Publishing country	England
Document type	Journal Article ; Review
ISSN	0360-1323
ISSN	0360-1323
DOI	10.1016/j.buildenv.2020.107472
Database	MEDical Literature Analysis and Retrieval System OnLINE

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