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  1. Article ; Online: Gut Microbiota and Chronic Diseases and Conditions.

    Franza, Laura / Cianci, Rossella

    Current medicinal chemistry

    2022  Volume 29, Issue 18, Page(s) 3145–3146

    MeSH term(s) Chronic Disease ; Gastrointestinal Microbiome ; Humans ; Renal Insufficiency, Chronic
    Language English
    Publishing date 2022-06-14
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 1319315-6
    ISSN 1875-533X ; 0929-8673
    ISSN (online) 1875-533X
    ISSN 0929-8673
    DOI 10.2174/092986732918220420133631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Recent Advances in Vaccine Technology and Design.

    Cianci, Rossella / Franza, Laura

    Vaccines

    2022  Volume 10, Issue 4

    Abstract: If up until three years ago, infectious diseases were a lesser concern when compared to non-communicable diseases in Western countries, the ongoing pandemic has reminded us that things are not so clean-cut [ ... ]. ...

    Abstract If up until three years ago, infectious diseases were a lesser concern when compared to non-communicable diseases in Western countries, the ongoing pandemic has reminded us that things are not so clean-cut [...].
    Language English
    Publishing date 2022-04-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10040624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent Advances in Vaccine Technology and Design

    Rossella Cianci / Laura Franza

    Vaccines, Vol 10, Iss 4, p

    2022  Volume 624

    Abstract: If up until three years ago, infectious diseases were a lesser concern when compared to non-communicable diseases in Western countries, the ongoing pandemic has reminded us that things are not so clean-cut [.] ...

    Abstract If up until three years ago, infectious diseases were a lesser concern when compared to non-communicable diseases in Western countries, the ongoing pandemic has reminded us that things are not so clean-cut [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Pollution, Inflammation, and Vaccines: A Complex Crosstalk.

    Franza, Laura / Cianci, Rossella

    International journal of environmental research and public health

    2021  Volume 18, Issue 12

    Abstract: The importance of pollution in determining human health is becoming increasingly clear, also given the dramatic consequences it has had on recent geopolitical events. Yet, the consequences of contamination are not always straightforward. In this paper, ... ...

    Abstract The importance of pollution in determining human health is becoming increasingly clear, also given the dramatic consequences it has had on recent geopolitical events. Yet, the consequences of contamination are not always straightforward. In this paper, we will discuss the effects of different pollutants on different aspects of human health, in particular on the immune system and inflammation. Different environmental pollutants can have different effects on the immune system, which can then promote complex pathologies, such as autoimmune disorders and cancer. The interaction with the microbiota also further helps to determine the consequences of contamination on wellbeing. The pollution can affect vaccination efficacy, given the widespread effects of vaccination on immunity. At the same time, some vaccinations also can exert protective effects against some forms of pollution.
    MeSH term(s) Environmental Pollution ; Humans ; Inflammation ; Microbiota ; Vaccination ; Vaccines/adverse effects
    Chemical Substances Vaccines
    Language English
    Publishing date 2021-06-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph18126330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Genomic Medicine and Advances in Vaccine Technology and Development in the Developing and Developed World

    Rossella Cianci / Laura Franza

    Vaccines, Vol 9, Iss 9, p

    2021  Volume 9

    Abstract: Vaccinations are one of the most effective public health measures available at present [.] ...

    Abstract Vaccinations are one of the most effective public health measures available at present [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Genomic Medicine and Advances in Vaccine Technology and Development in the Developing and Developed World.

    Cianci, Rossella / Franza, Laura

    Vaccines

    2020  Volume 9, Issue 1

    Abstract: Vaccinations are one of the most effective public health measures available at present [ ... ]. ...

    Abstract Vaccinations are one of the most effective public health measures available at present [...].
    Language English
    Publishing date 2020-12-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines9010009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pollution, Inflammation, and Vaccines

    Laura Franza / Rossella Cianci

    International Journal of Environmental Research and Public Health, Vol 18, Iss 6330, p

    A Complex Crosstalk

    2021  Volume 6330

    Abstract: The importance of pollution in determining human health is becoming increasingly clear, also given the dramatic consequences it has had on recent geopolitical events. Yet, the consequences of contamination are not always straightforward. In this paper, ... ...

    Abstract The importance of pollution in determining human health is becoming increasingly clear, also given the dramatic consequences it has had on recent geopolitical events. Yet, the consequences of contamination are not always straightforward. In this paper, we will discuss the effects of different pollutants on different aspects of human health, in particular on the immune system and inflammation. Different environmental pollutants can have different effects on the immune system, which can then promote complex pathologies, such as autoimmune disorders and cancer. The interaction with the microbiota also further helps to determine the consequences of contamination on wellbeing. The pollution can affect vaccination efficacy, given the widespread effects of vaccination on immunity. At the same time, some vaccinations also can exert protective effects against some forms of pollution.
    Keywords pollution ; vaccination ; inflammation ; immunity ; microbiota ; Medicine ; R
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Delirium in head trauma: looking for a culprit.

    Villani, Emanuele Rocco / Franza, Laura / Cianci, Rossella

    Reviews on recent clinical trials

    2022  

    Abstract: Head trauma and delirium are two common conditions in the elderly population. They both carry a heavy burden in terms of mortality and morbidity and are associated with one another through several environmental and clinical factors, such as comorbidities, ...

    Abstract Head trauma and delirium are two common conditions in the elderly population. They both carry a heavy burden in terms of mortality and morbidity and are associated with one another through several environmental and clinical factors, such as comorbidities, age, and sex. One factor that may play a role in both these conditions is inflammation, which might also represent a link between these two conditions.. In particular, head trauma can cause both systemic and neuroinflammation, while delirium appears to be precipitated by inflammatory conditions, while also involving a number of inflammatory pathways in its pathogenesis. Interleukin 6 and tumor necrosis factor α are only two of the main actors in this crosstalk, which also involves microglia and immune cells. An indirect proof is that anti-inflammatory drugs, have proven effective in reducing posttraumatic delirium, thus demonstrating the importance of inflammation in the pathophysiology of this disease. In this paper, we have revised the available literature exploring the links between inflammation, head trauma and delirium and we will discuss the mechanisms of this relationship, paying particular attention to the possible future implications.
    Language English
    Publishing date 2022-08-11
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2251879-4
    ISSN 1876-1038 ; 1574-8871
    ISSN (online) 1876-1038
    ISSN 1574-8871
    DOI 10.2174/1574887117666220811090608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Gut-Kidney-Heart: A Novel Trilogy.

    Caldarelli, Mario / Franza, Laura / Rio, Pierluigi / Gasbarrini, Antonio / Gambassi, Giovanni / Cianci, Rossella

    Biomedicines

    2023  Volume 11, Issue 11

    Abstract: The microbiota represents a key factor in determining health and disease. Its role in inflammation and immunological disorders is well known, but it is also involved in several complex conditions, ranging from neurological to psychiatric, from ... ...

    Abstract The microbiota represents a key factor in determining health and disease. Its role in inflammation and immunological disorders is well known, but it is also involved in several complex conditions, ranging from neurological to psychiatric, from gastrointestinal to cardiovascular diseases. It has recently been hypothesized that the gut microbiota may act as an intermediary in the close interaction between kidneys and the cardiovascular system, leading to the conceptualization of the "gut-kidney-heart" axis. In this narrative review, we will discuss the impact of the gut microbiota on each system while also reviewing the available data regarding the axis itself. We will also describe the role of gut metabolites in this complex interplay, as well as potential therapeutical perspectives.
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11113063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Thymus-kidneys: a dangerous liaison.

    Rio, Pierluigi / Cavallaro, Chiara / Diomedi-Camassei, Francesca / Cianci, Rossella / Gambassi, Giovanni

    Internal and emergency medicine

    2022  Volume 17, Issue 7, Page(s) 2057–2061

    MeSH term(s) Humans ; Kidney ; Thymus Gland
    Language English
    Publishing date 2022-06-25
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03021-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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