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  1. Article ; Online: CDC LOCATe: discrepancies between self-reported level of maternal care and LOCATe-assessed level of maternal care among 463 birth facilities.

    Madni, Sabrina A / Ewing, Alexander C / Beauregard, Jennifer L / Brantley, Mary D / Menard, M Kathryn / Goodman, David A

    Journal of perinatology : official journal of the California Perinatal Association

    2021  Volume 42, Issue 5, Page(s) 589–594

    Abstract: Objective: Describe sources of discrepancy between self-assessed LoMC (level of maternal care) and CDC LOCATe: Study design: CDC LOCATe: Result: Among 418 facilities that self-reported an LoMC, 41.4% self-reported a higher LoMC than their LOCATe!## ...

    Abstract Objective: Describe sources of discrepancy between self-assessed LoMC (level of maternal care) and CDC LOCATe
    Study design: CDC LOCATe
    Result: Among 418 facilities that self-reported an LoMC, 41.4% self-reported a higher LoMC than their LOCATe
    Conclusion: Two in five facilities self-report a LoMC higher than their LOCATe
    MeSH term(s) Centers for Disease Control and Prevention, U.S. ; Cross-Sectional Studies ; Delivery, Obstetric ; Female ; Health Facilities ; Health Services Accessibility ; Humans ; Pregnancy ; Self Report ; United States
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-021-01268-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2412: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: COVID-19-Associated Deaths After SARS-CoV-2 Infection During Pregnancy - Mississippi, March 1, 2020-October 6, 2021.

    Kasehagen, Laurin / Byers, Paul / Taylor, Kathryn / Kittle, Theresa / Roberts, Christine / Collier, Charlene / Rust, Britney / Ricaldi, Jessica N / Green, Jamilla / Zapata, Lauren B / Beauregard, Jennifer / Dobbs, Thomas

    MMWR. Morbidity and mortality weekly report

    2021  Volume 70, Issue 47, Page(s) 1646–1648

    Abstract: Pregnant and recently pregnant women are at increased risk for severe illness and death from COVID-19 compared with women who are not pregnant or were not recently pregnant (1,2). CDC recommends COVID-19 vaccination for women who are pregnant, recently ... ...

    Abstract Pregnant and recently pregnant women are at increased risk for severe illness and death from COVID-19 compared with women who are not pregnant or were not recently pregnant (1,2). CDC recommends COVID-19 vaccination for women who are pregnant, recently pregnant, trying to become pregnant, or might become pregnant in the future.*
    MeSH term(s) Adult ; COVID-19/mortality ; COVID-19 Vaccines/administration & dosage ; Centers for Disease Control and Prevention, U.S. ; Female ; Humans ; Mississippi/epidemiology ; Practice Guidelines as Topic ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Risk Assessment ; United States ; Young Adult
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-11-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm7047e2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1827: Show issues Location:
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  3. Article ; Online: Trajectories of Acute Diabetes-Specific Stress in Adolescents With Type 1 Diabetes and Their Caregivers Within the First Year of Diagnosis.

    Yi-Frazier, Joyce P / Cochrane, Katie / Whitlock, Kathryn / Rosenberg, Abby R / Pascual, Michael / Beauregard, Natalie / Mitrovich, Connor / Panlasigui, Neil / Pihoker, Catherine

    Journal of pediatric psychology

    2017  Volume 43, Issue 6, Page(s) 645–653

    Abstract: Objectives: Our aims were to describe stress trajectories for newly diagnosed type 1 diabetes (T1D) in adolescents and their parents, explore whether resilience is associated with stress trajectories, and to examine the effects of stress trajectories on ...

    Abstract Objectives: Our aims were to describe stress trajectories for newly diagnosed type 1 diabetes (T1D) in adolescents and their parents, explore whether resilience is associated with stress trajectories, and to examine the effects of stress trajectories on diabetes-specific outcomes.
    Methods: Fifty-nine youth aged 10-18 years with newly diagnosed T1D and a primary caregiver were followed for 12 months. Stress and resilience were assessed using questionnaires every 3 months, and diabetes-specific outcomes (self-care, quality of life, and hemoglobin A1C) at 6 and 12 months. Parent and adolescent stress trajectories were identified using semiparametric group-based modeling.
    Results: Four stress trajectories emerged for parents and three emerged for adolescents. Adolescent trajectories were stable throughout the 12 months, and those with stable low stress had the highest levels of resilience. Further, the stable low stress group had higher quality of life scores at 12-month postdiagnosis. In contrast, stress for parents changed considerably over the 12-month period, and trajectory groups did not associate with 12-month outcomes.
    Conclusions: Distinct patterns of stress emerged for both the adolescent and parent cohorts. Resilience at the time of diagnosis was particularly protective for adolescents. These results suggest that stress-reducing and resilience-promoting interventions for newly diagnosed adolescents with T1D may have potential to improve longer-term outcomes.
    MeSH term(s) Adolescent ; Caregivers/psychology ; Child ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/psychology ; Female ; Follow-Up Studies ; Humans ; Male ; Parents/psychology ; Quality of Life ; Resilience, Psychological ; Stress, Psychological/diagnosis ; Stress, Psychological/etiology ; Stress, Psychological/psychology ; Surveys and Questionnaires
    Language English
    Publishing date 2017-12-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 625329-5
    ISSN 1465-735X ; 0146-8693
    ISSN (online) 1465-735X
    ISSN 0146-8693
    DOI 10.1093/jpepsy/jsy003
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    Zs.A 1713: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: A dual radiologic contrast agent protocol for 18F-FDG and 18F-FLT PET/CT imaging of mice bearing abdominal tumors.

    Aide, Nicolas / Kinross, Kathryn / Beauregard, Jean-Mathieu / Neels, Oliver / Potdevin, Titaina / Roselt, Peter / Dorow, Donna / Cullinane, Carleen / Hicks, Rodney J

    Molecular imaging and biology

    2010  Volume 13, Issue 3, Page(s) 518–525

    Abstract: Purpose: The aim of the study was to improve abdominal tumor detection by use of a dual radiologic contrast protocol.: Procedures: eXia160® (Benitio international) was mixed with 2-deoxy-2-[¹⁸F]fluoro-D: -glucose or 3'-[¹⁸F]fluoro-3'-deoxythymidine ... ...

    Abstract Purpose: The aim of the study was to improve abdominal tumor detection by use of a dual radiologic contrast protocol.
    Procedures: eXia160® (Benitio international) was mixed with 2-deoxy-2-[¹⁸F]fluoro-D: -glucose or 3'-[¹⁸F]fluoro-3'-deoxythymidine for intravenous (IV) injections. Omnipaque® 300 (GE healthcare) was used for intraperitoneal (IP) injections. Positron emission tomography/computed tomography (PET/CT) scans were acquired on a Siemens Biograph® equipped with point spread function reconstruction. The optimal concentration and injection schedule of IP contrast agent was studied in 12 mice. The impact of IP contrast media on PET quantitative accuracy was investigated by phantom studies and by imaging six mice before and after IP injection of Omnipaque®. The impact of a dual contrast media protocol on tumor delineation and quantitation was evaluated in 15 tumor-bearing mice using ex vivo counting as the reference.
    Results: The optimal sequence was a mixture of tracer plus IV contrast agent followed by 1 mL of IP contrast agent (20 mg iodine/mL) administered 10 min before PET/CT acquisition. Phantom studies showed that the use of a 20-mg iodine/mL concentration of Omnipaque® led to a 4.8% overestimation of radioactivity concentration, as compared to saline. This was confirmed by animal studies that demonstrated a 4.3% overestimation. Tumor detection was excellent and correlation between PET/CT quantitative data and ex vivo counting was good (r² = 0.91, slope = 0.7).
    Conclusions: A dual radiologic contrast protocol is useful in PET/CT scanning of mice bearing abdominal tumors. Contrast agents used in this manner lead to a small but acceptable overestimation of quantitative PET data.
    MeSH term(s) Abdominal Neoplasms/diagnostic imaging ; Animals ; Ascites/pathology ; Contrast Media/administration & dosage ; Dideoxynucleosides/administration & dosage ; Fluorodeoxyglucose F18/administration & dosage ; Injections, Intravenous ; Mice ; Positron-Emission Tomography ; Tomography, X-Ray Computed
    Chemical Substances Contrast Media ; Dideoxynucleosides ; Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; alovudine (PG53R0DWDQ)
    Language English
    Publishing date 2010-07-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2079160-4
    ISSN 1860-2002 ; 1536-1632
    ISSN (online) 1860-2002
    ISSN 1536-1632
    DOI 10.1007/s11307-010-0378-x
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    Zs.A 6468: Show issues Location:
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  5. Article ; Online: High throughput static and dynamic small animal imaging using clinical PET/CT: potential preclinical applications.

    Aide, Nicolas / Desmonts, Cédric / Beauregard, Jean-Mathieu / Beyer, Thomas / Kinross, Kathryn / Roselt, Peter / Neels, Oliver / Agostini, Denis / Bardet, Stéphane / Bouvard, Gérard / Hicks, Rodney J

    European journal of nuclear medicine and molecular imaging

    2010  Volume 37, Issue 5, Page(s) 991–1001

    Abstract: Purpose: The objective of the study was to evaluate state-of-the-art clinical PET/CT technology in performing static and dynamic imaging of several mice simultaneously.: Methods: A mouse-sized phantom was imaged mimicking simultaneous imaging of ... ...

    Abstract Purpose: The objective of the study was to evaluate state-of-the-art clinical PET/CT technology in performing static and dynamic imaging of several mice simultaneously.
    Methods: A mouse-sized phantom was imaged mimicking simultaneous imaging of three mice with computation of recovery coefficients (RCs) and spillover ratios (SORs). Fifteen mice harbouring abdominal or subcutaneous tumours were imaged on clinical PET/CT with point spread function (PSF) reconstruction after injection of [18F]fluorodeoxyglucose or [18F]fluorothymidine. Three of these mice were imaged alone and simultaneously at radial positions -5, 0 and 5 cm. The remaining 12 tumour-bearing mice were imaged in groups of 3 to establish the quantitative accuracy of PET data using ex vivo gamma counting as the reference. Finally, a dynamic scan was performed in three mice simultaneously after the injection of (68)Ga-ethylenediaminetetraacetic acid (EDTA).
    Results: For typical lesion sizes of 7-8 mm phantom experiments indicated RCs of 0.42 and 0.76 for ordered subsets expectation maximization (OSEM) and PSF reconstruction, respectively. For PSF reconstruction, SOR(air) and SOR(water) were 5.3 and 7.5%, respectively. A strong correlation (r (2) = 0.97, p < 0.0001) between quantitative data obtained in mice imaged alone and simultaneously in a group of three was found following PSF reconstruction. The correlation between ex vivo counting and PET/CT data was better with PSF reconstruction (r (2) = 0.98; slope = 0.89, p < 0.0001) than without (r (2) = 0.96; slope = 0.62, p < 0.001). Valid time-activity curves of the blood pool, kidneys and bladder could be derived from (68)Ga-EDTA dynamic acquisition.
    Conclusion: New generation clinical PET/CT can be used for simultaneous imaging of multiple small animals in experiments requiring high throughput and where a dedicated small animal PET system is not available.
    MeSH term(s) Animals ; Edetic Acid ; Mice ; Phantoms, Imaging ; Positron-Emission Tomography/methods ; Time Factors ; Tomography, X-Ray Computed/methods
    Chemical Substances Edetic Acid (9G34HU7RV0)
    Language English
    Publishing date 2010-01-27
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-009-1352-1
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    Zs.A 1227: Show issues Location:
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