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  1. Article ; Online: Artificial Intelligence and Breast US: Radiologists Won't Regret Opening Pandora's Box.

    Mesurolle, Benoît / El-Khoury, Mona

    Academic radiology

    2024  

    Language English
    Publishing date 2024-04-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2024.03.038
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    Zs.A 4594: Show issues Location:
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  2. Article ; Online: Pre-operative MRI in patients with ductal carcinoma in situ: the ongoing debate.

    El Khoury, Mona / Mesurolle, Benoit

    European radiology

    2023  

    Language English
    Publishing date 2023-11-24
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-023-10460-2
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    Zs.A 3300: Show issues Location:
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  3. Article ; Online: Satiety: a gut-brain-relationship.

    Barakat, Ghinwa M / Ramadan, Wiam / Assi, Ghaith / Khoury, Noura B El

    The journal of physiological sciences : JPS

    2024  Volume 74, Issue 1, Page(s) 11

    Abstract: Many hormones act on the hypothalamus to control hunger and satiety through various pathways closely associated with several factors. When food is present in the gastro intestinal (GI) tract, enteroendocrine cells (EECs) emit satiety signals such as ... ...

    Abstract Many hormones act on the hypothalamus to control hunger and satiety through various pathways closely associated with several factors. When food is present in the gastro intestinal (GI) tract, enteroendocrine cells (EECs) emit satiety signals such as cholecystokinin (CCK), glucagon like peptide-1 (GLP-1) and peptide YY (PYY), which can then communicate with the vagus nerve to control food intake. More specifically, satiety has been shown to be particularly affected by the GLP-1 hormone and its receptor agonists that have lately been acknowledged as a promising way to reduce weight. In addition, there is increasing evidence that normal flora is also involved in the peripheral, central, and reward system that impact satiety. Moreover, neurologic pathways control satiety through neurotransmitters. In this review, we discuss the different roles of each of the GLP-1 hormone and its agonist, gut microbiomes, as well as neurotransmitters and their interconnected relation in the regulation of body's satiety homeostasis.
    MeSH term(s) Cholecystokinin/metabolism ; Glucagon-Like Peptide 1 ; Peptide YY/metabolism ; Brain/metabolism ; Neurotransmitter Agents
    Chemical Substances Cholecystokinin (9011-97-6) ; Glucagon-Like Peptide 1 (89750-14-1) ; Peptide YY (106388-42-5) ; Neurotransmitter Agents
    Language English
    Publishing date 2024-02-17
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 2234472-X
    ISSN 1880-6562 ; 1880-6546
    ISSN (online) 1880-6562
    ISSN 1880-6546
    DOI 10.1186/s12576-024-00904-9
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  4. Article ; Online: Youth involvement in serious physical violence and political violence: Similarities and differences in risk factors.

    Khoury-Kassabri, Mona / Hasisi, Badi / Itskovich, Eran

    Journal of adolescence

    2024  

    Abstract: Introduction: Youth involvement in violence and delinquency has received widespread attention in the literature. However, little is known about youth involvement in political violence, especially among youth who live in conflict areas. The current study ...

    Abstract Introduction: Youth involvement in violence and delinquency has received widespread attention in the literature. However, little is known about youth involvement in political violence, especially among youth who live in conflict areas. The current study examined the mechanisms that underlie youth involvement in serious physical and political violence. We explored the similarities and differences in the association between both individual factors (including religiosity and school commitment) and parental factors (including parental control and education), and the two types of violent behaviors.
    Method: A large representative sample of 814 Arab male students from neighborhoods located in East Jerusalem, aged 12-18 years, completed a structured, anonymous, self-report questionnaire. The data was collected between February and May 2019.
    Results: Over half of the participants reported that they had been involved in political violence (55.1%) or serious physical violence (58.8%) during the previous year. Youth involvement in serious physical violence was positively associated with involvement in political violence. Furthermore, we found that greater parental control and lower impulsivity are associated with lower levels of political and physical violence. School commitment was associated negatively with serious physical violence but not with involvement in political violence. Youth work was positively correlated with involvement in political violence but not in serious physical violence.
    Conclusion: The results of the current study show that Arab youth from East Jerusalem are highly involved in political and serious physical violence. The risk and protective factors identified here should inform the design of specific intervention strategies.
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 303529-3
    ISSN 1095-9254 ; 0140-1971
    ISSN (online) 1095-9254
    ISSN 0140-1971
    DOI 10.1002/jad.12325
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  5. Article: Complete Atrioventricular Canal Defect in a Non-syndromic Adult Patient: An Unusual Presentation.

    Nabhan, Elias M / Khoury, Samih B / Bechara, Tony E

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43186

    Abstract: This case report presents a 30-year-old male patient with a history of autism spectrum disorder who experienced a drastic decline in physical activity in recent years. Upon examination, the patient was found to be relatively bedridden, lethargic, and ... ...

    Abstract This case report presents a 30-year-old male patient with a history of autism spectrum disorder who experienced a drastic decline in physical activity in recent years. Upon examination, the patient was found to be relatively bedridden, lethargic, and unable to maintain an upright gait, accompanied by severe clubbing. Transthoracic echocardiography revealed a massive 4 cm complete atrioventricular canal (CAVC) defect. Although the patient was asymptomatic throughout most of his life, the CAVC defect appeared to have progressively impacted his health and activity tolerance. The importance of a multidisciplinary approach in early detection and timely intervention in managing CAVC defect is emphasized in this case.
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43186
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  6. Article: Mental Health: Pandemics, Epidemics and Tau Protein.

    Barakat, Ghinwa M / Assi, Ghaith / El Khoury, Noura B

    Clinical practice and epidemiology in mental health : CP & EMH

    2023  Volume 19, Page(s) e174501792305020

    Abstract: Background: It is well established that a wide range of psychological disorders are influenced by the way people live, with lifestyle-related factors playing a substantial role. During the past decade, the effects of major disasters on mental health ... ...

    Abstract Background: It is well established that a wide range of psychological disorders are influenced by the way people live, with lifestyle-related factors playing a substantial role. During the past decade, the effects of major disasters on mental health have drawn a lot of attention.
    Aim: In this review, we compare clinical studies reporting a link between COVID-19 and other pandemics and mental health. Importantly, we also shed light on Tau protein and neurotransmitters as neurobiological factors that might explain this link.
    Methods: A thorough PubMed search was done to gather and summarize published data on the COVID-19 pandemic's effect on mental health. Additionally, these studies were compared to previous research published on PubMed, triggering other pandemic and epidemic impacts on mental health.
    Results: The COVID-19 epidemic has had the biggest impact on raising awareness about mental health. Moreover, the past century has seen an increase in the frequency of disease outbreaks like MERS-CoV, Ebola, and Influenza, which all had an impact on mental health. However, the exact role of these epidemics on mental health and brain functions is poorly understood.
    Conclusion: Future research on the underlying pathways may yield essential information for the treatment and prevention of prospective mental diseases in light of the ongoing decline in mental health during the past 10 years.
    Language English
    Publishing date 2023-06-21
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2559748-6
    ISSN 1745-0179
    ISSN 1745-0179
    DOI 10.2174/17450179-v19-e230510-2022-51
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  7. Article ; Online: Which emotion-regulation strategies explain the relationship between dispositional mindfulness, self-compassion, and eating to cope?

    Wisener, Melanie / Khoury, Bassam

    Appetite

    2022  Volume 172, Page(s) 105912

    Abstract: ... mindfulness and self-compassion with eating to cope. Undergraduate students (N = 307) aged 18 to 24 (M = 20.28 ...

    Abstract Eating in response or to cope with negative emotions has been shown to be problematic in undergraduate students. Dispositional mindfulness and self-compassion have been associated with less eating in response or to cope with negative emotions; however, specific mechanisms underlying these relationships have never been tested. The aim of the present study is to test whether lower levels of specific difficulties in emotion-regulation (i.e., non-acceptance of emotional responses, difficulties engaging in goal-directed behaviour, impulse control difficulties, lack of emotional awareness, limited access to emotion-regulation strategies, lack of emotional clarity) explain the negative relationship between dispositional mindfulness and self-compassion with eating to cope. Undergraduate students (N = 307) aged 18 to 24 (M = 20.28) completed online self-report measures. Dispositional mindfulness and self-compassion were associated with lower levels of non-acceptance of emotional responses, which in turn was associated with less eating to cope. Dispositional mindfulness and self-compassion were also associated with lower levels of difficulties engaging in goal-directed behaviour; however, difficulties engaging in goal-directed behaviour was unexpectedly associated with less eating to cope. To note, dispositional mindfulness was not associated with eating to cope when holding self-compassion constant. Results suggest that specific difficulties in emotion-regulation may explain the negative relationship between dispositional mindfulness and self-compassion with eating to cope. Findings contribute to theoretical models, and with replication can be used to inform the development of randomized-control trials examining the efficacy of mindfulness and self-compassion-based training for eating to cope in undergraduate students.
    MeSH term(s) Adaptation, Psychological ; Adolescent ; Adult ; Emotions ; Empathy ; Humans ; Mindfulness ; Self-Compassion ; Young Adult
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2022.105912
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  8. Article: Clinical Predictors of Gastrointestinal Bleeding Source before Computed Tomography Angiography.

    Sbeit, Wisam / Basheer, Maamoun / Shahin, Amir / Khoury, Sharbel / Msheael, Botros / Assy, Nimer / Khoury, Tawfik

    Journal of clinical medicine

    2023  Volume 12, Issue 24

    Abstract: Background: Acute gastrointestinal bleeding (GIB) is a commonly encountered medical emergency. In cases of negative endoscopic evaluations, computed tomography angiography (CTA) is usually the next diagnostic step. To date, data regarding positive CTA ... ...

    Abstract Background: Acute gastrointestinal bleeding (GIB) is a commonly encountered medical emergency. In cases of negative endoscopic evaluations, computed tomography angiography (CTA) is usually the next diagnostic step. To date, data regarding positive CTA examinations are lacking. We aimed to assess the clinical and laboratory parameters that predict a positive CTA examination, as demonstrated by the extravasation of contrast material into the bowel lumen.
    Methods: We performed a single-center retrospective study, including all patients who were admitted with GIB and who underwent CTA. Analysis was performed to compare patients' characteristics, and logistic regression was used to explore parameters associated with a positive CTA.
    Results: We included 154 patients. Of them, 25 patients (16.2%) had active GIB on CTA vs. 129 patients (83.8%) who did not. On univariate analysis, several parameters were positively associated with active GIB, including congestive heart failure (OR 2.47, 95% CI 1.04-5.86,
    Conclusions: We could identify high INR and low albumin as strong predictors of active GIB, as demonstrated by positive CTA. On the other hand, comorbid patients classified by a high ASA score did not experience a higher rate of active GIB.
    Language English
    Publishing date 2023-12-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12247696
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  9. Article ; Online: Dilemmas in the management of rhinophyma in pigmented individuals.

    Johnson, M / Khoury, A / Dheansa, B

    Annals of the Royal College of Surgeons of England

    2021  Volume 103, Issue 5, Page(s) e165–e168

    Abstract: Rhinophyma affects predominantly the Caucasian population and is rare in those with Fitzpatrick skin type IV-VI. Diagnosis is based on clinical evaluation. Prominent features include abnormal coloration and texture of skin, impaired vascularity, ... ...

    Abstract Rhinophyma affects predominantly the Caucasian population and is rare in those with Fitzpatrick skin type IV-VI. Diagnosis is based on clinical evaluation. Prominent features include abnormal coloration and texture of skin, impaired vascularity, irregular nodular exophytic growth and telangiectasia. Management can be surgical or dermatological. Surgery remains the mainstay of treatment but achieving an acceptable aesthetic result can be challenging, particularly in those with pigmented skin. Postsurgical hyper- and hypopigmentation make for unpredictable outcomes requiring appropriate preoperative counselling. We present a case that exemplifies this issue and discuss our recommended approach to counselling, consenting and managing such dilemmas in these patients, and a proposal for further investigation into the role of autologous melanocyte transplantation in reducing the effect particularly of hypopigmentation on aesthetic outcomes in this group.
    MeSH term(s) Dermatologic Surgical Procedures/adverse effects ; Esthetics ; Humans ; Hyperpigmentation/etiology ; Hypopigmentation/etiology ; Male ; Melanocytes ; Middle Aged ; Patient Satisfaction ; Rhinophyma/pathology ; Rhinophyma/surgery ; Skin/pathology
    Language English
    Publishing date 2021-05-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2020.7081
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  10. Article ; Online: Breast Mammographic Screening: The More Mammograms Read, the Better the Performance.

    El Khoury, Mona / Mesurolle, Benoit

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2021  Volume 73, Issue 2, Page(s) 289–290

    MeSH term(s) Breast ; Breast Neoplasms/diagnostic imaging ; Early Detection of Cancer ; Female ; Humans ; Mammography ; Mass Screening
    Language English
    Publishing date 2021-09-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371211040699
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