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  1. Article: Erratum: The Protective Effect of

    Choi, Soo In / Kim, Nayoung / Nam, Ryoung Hee / Jang, Jae Young / Kim, Eun Hye / Ha, SungChan / Kang, Kisung / Lee, Wonseok / Choi, HyeLim / Kim, Yeon-Ran / Seok, Yeong-Jae / Shin, Cheol Min / Lee, Dong Ho

    Journal of cancer prevention

    2024  Volume 28, Issue 4, Page(s) 219

    Abstract: This corrects the article on p. 93 in vol. 28, PMID: 37830115.]. ...

    Abstract [This corrects the article on p. 93 in vol. 28, PMID: 37830115.].
    Language English
    Publishing date 2024-01-05
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 3019805-7
    ISSN 2288-3657 ; 2288-3649
    ISSN (online) 2288-3657
    ISSN 2288-3649
    DOI 10.15430/JCP.2023.28.4.219
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment

    Hye Jin Kim / Hui Bang Cho / Hye-Ryoung Kim / Sujeong Lee / Ji-in Park / Keun-Hong Park

    Nano Convergence, Vol 11, Iss 1, Pp 1-

    2024  Volume 16

    Abstract: Abstract Photoporation techniques based on plasmonic nanoparticles such as gold nanoparticles have been extensively studied for the intracellular delivery of substances via cell membrane disruption. However, the clinical application of AuNP is ... ...

    Abstract Abstract Photoporation techniques based on plasmonic nanoparticles such as gold nanoparticles have been extensively studied for the intracellular delivery of substances via cell membrane disruption. However, the clinical application of AuNP is challenging due to its absorption in the 500 nm region of the light spectrum. To overcome this challenge, upconversion nanoparticles were employed to stimulate AuNP at NIR wavelengths. posAuNP@UCNPs nanocomposites were produced by coating 30 nm UCNPs on 80 nm AuNPs using DOPA-PEI, which were then irradiated with 980 nm NIR light to facilitate their intracellular delivery. TEM and DLS confirmed that posAuNP and UCNP combine to form nanocomposites. Additionally, multiphysics simulation was used to analyze the distribution of the posAuNP electric field based on morphological differences that change as the UCNP ratio increases. Next, effective LED irradiation conditions were established by applying upconverting-photon quenching-mediated perforation influx to C28/I2 cells as suspensions or spheroids. posAuNP@UCNP nanocomposites were confirmed to be effective for the delivery of baricitinib as a treatment for osteoarthritis in a three-dimensional osteoarthritis model. Finally, chondrocyte differentiation was induced through intracellular delivery of baricitinib using posAuNP@UCNPs. The findings suggest that posAuNP@UCNPs have great potential as a tool for non-invasive drug delivery via UCPPin. Graphical Abstract
    Keywords Upconversion nanoparticles ; Au nanoparticles ; Intracellular delivery ; Photoporation ; NIR ; Osteoarthritis ; Technology ; T ; Chemical technology ; TP1-1185 ; Biotechnology ; TP248.13-248.65 ; Science ; Q ; Physics ; QC1-999
    Subject code 500
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Ambipolar Thickness-Dependent Thermoelectric Measurements of WSe

    Chen, Victoria / Lee, Hye Ryoung / Köroğlu, Çağıl / McClellan, Connor J / Daus, Alwin / Pop, Eric

    Nano letters

    2023  Volume 23, Issue 10, Page(s) 4095–4100

    Abstract: Thermoelectric materials can harvest electrical energy from temperature gradients, and could play a role as power supplies for sensors and other devices. Here, we characterize fundamental in-plane electrical and thermoelectric properties of layered ... ...

    Abstract Thermoelectric materials can harvest electrical energy from temperature gradients, and could play a role as power supplies for sensors and other devices. Here, we characterize fundamental in-plane electrical and thermoelectric properties of layered WSe
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.2c03468
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment.

    Kim, Hye Jin / Cho, Hui Bang / Kim, Hye-Ryoung / Lee, Sujeong / Park, Ji-In / Park, Keun-Hong

    Nano convergence

    2024  Volume 11, Issue 1, Page(s) 1

    Abstract: Photoporation techniques based on plasmonic nanoparticles such as gold nanoparticles have been extensively studied for the intracellular delivery of substances via cell membrane disruption. However, the clinical application of AuNP is challenging due to ... ...

    Abstract Photoporation techniques based on plasmonic nanoparticles such as gold nanoparticles have been extensively studied for the intracellular delivery of substances via cell membrane disruption. However, the clinical application of AuNP is challenging due to its absorption in the 500 nm region of the light spectrum. To overcome this challenge, upconversion nanoparticles were employed to stimulate AuNP at NIR wavelengths. posAuNP@UCNPs nanocomposites were produced by coating 30 nm UCNPs on 80 nm AuNPs using DOPA-PEI, which were then irradiated with 980 nm NIR light to facilitate their intracellular delivery. TEM and DLS confirmed that posAuNP and UCNP combine to form nanocomposites. Additionally, multiphysics simulation was used to analyze the distribution of the posAuNP electric field based on morphological differences that change as the UCNP ratio increases. Next, effective LED irradiation conditions were established by applying upconverting-photon quenching-mediated perforation influx to C28/I2 cells as suspensions or spheroids. posAuNP@UCNP nanocomposites were confirmed to be effective for the delivery of baricitinib as a treatment for osteoarthritis in a three-dimensional osteoarthritis model. Finally, chondrocyte differentiation was induced through intracellular delivery of baricitinib using posAuNP@UCNPs. The findings suggest that posAuNP@UCNPs have great potential as a tool for non-invasive drug delivery via UCPPin.
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2760386-6
    ISSN 2196-5404 ; 2196-5404
    ISSN (online) 2196-5404
    ISSN 2196-5404
    DOI 10.1186/s40580-023-00409-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Melatonin loaded PLGA nanoparticles effectively ameliorate the

    Lee, Sujin / Kim, Hye Jin / Cho, Hui Bang / Kim, Hye-Ryoung / Lee, Sujeong / Park, Ji-In / Park, Keun-Hong

    Biomaterials science

    2023  Volume 11, Issue 8, Page(s) 2912–2923

    Abstract: Almost all cells can be exposed to stress, but oocytes, which are female germ cells, are particularly vulnerable to damage. In this study, melatonin, a well-known antioxidant, was loaded into biodegradable poly(lactic- ...

    Abstract Almost all cells can be exposed to stress, but oocytes, which are female germ cells, are particularly vulnerable to damage. In this study, melatonin, a well-known antioxidant, was loaded into biodegradable poly(lactic-
    MeSH term(s) Female ; Male ; Animals ; Vitrification ; Melatonin/pharmacology ; Oocytes ; Antioxidants ; Etoposide ; Nanoparticles
    Chemical Substances Melatonin (JL5DK93RCL) ; Antioxidants ; Etoposide (6PLQ3CP4P3)
    Language English
    Publishing date 2023-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2693928-9
    ISSN 2047-4849 ; 2047-4830
    ISSN (online) 2047-4849
    ISSN 2047-4830
    DOI 10.1039/d2bm02054h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Sex Difference in the Effect of

    Choi, Soo In / Kim, Nayoung / Nam, Ryoung Hee / Jang, Jae Young / Kim, Eun Hye / Ha, SungChan / Kang, Kisung / Lee, Wonseok / Shin, Cheol Min / Lee, Dong Ho

    Journal of cancer prevention

    2024  Volume 29, Issue 1, Page(s) 16–23

    Abstract: Dysbiosis in gut microbiota is known to contribute to development of irritable bowel syndrome. We tried to investigate the effect ... ...

    Abstract Dysbiosis in gut microbiota is known to contribute to development of irritable bowel syndrome. We tried to investigate the effect of
    Language English
    Publishing date 2024-03-29
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3019805-7
    ISSN 2288-3657 ; 2288-3649
    ISSN (online) 2288-3657
    ISSN 2288-3649
    DOI 10.15430/JCP.23.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Protective Effect of

    Choi, Soo In / Kim, Nayoung / Nam, Ryoung Hee / Jang, Jae Young / Kim, Eun Hye / Ha, SungChan / Kang, Kisung / Lee, Wonseok / Choi, HyeLim / Kim, Yeon-Ran / Seok, Yeong-Jae / Shin, Cheol Min / Lee, Dong Ho

    Journal of cancer prevention

    2023  Volume 28, Issue 3, Page(s) 93–105

    Abstract: Roseburia faecis, ...

    Abstract Roseburia faecis,
    Language English
    Publishing date 2023-10-13
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3019805-7
    ISSN 2288-3657 ; 2288-3649
    ISSN (online) 2288-3657
    ISSN 2288-3649
    DOI 10.15430/JCP.2023.28.3.93
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Light emitting diode (LED) irradiation of liposomes enhances drug encapsulation and delivery for improved cancer eradication.

    Lee, Sujeong / Kim, Hye Jin / Choi, Jin-Ho / Jang, Hye Jung / Cho, Hui Bang / Kim, Hye-Ryoung / Park, Ji-In / Park, Kyung-Soon / Park, Keun-Hong

    Journal of controlled release : official journal of the Controlled Release Society

    2024  Volume 368, Page(s) 756–767

    Abstract: Liposomes are widely used as drug delivery nanoplatforms because of their versatility and biocompatibility; however, their ability to load certain drugs may be suboptimal. In this study, we generated liposomes using a combination of DSPE and DSPE-PEG-2 k ...

    Abstract Liposomes are widely used as drug delivery nanoplatforms because of their versatility and biocompatibility; however, their ability to load certain drugs may be suboptimal. In this study, we generated liposomes using a combination of DSPE and DSPE-PEG-2 k lipids and loaded them with doxorubicin (DOX) and paclitaxel (PTX), to investigate the effects of light emitting diode (LED) irradiation on liposome structure and drug loading efficiency. Scanning and transmission electron microscopy revealed that the surface of liposomes irradiated with blue or near-infrared LEDs (LsLipo) was rougher and more irregular than that of non-LED-irradiated liposomes (NsLipo). Nuclear magnetic resonance analysis showed that the hydrogen peak originating from the lipid head groups was lower in LsLipo than in NsLipo preparations, indicating that LED irradiation changed the chemical and physical properties of the liposome. Structural changes, such as reduced rigidity, induced by LED irradiation, increased the loading efficiency of DOX and PTX. In vitro and in vivo experiments showed that LsLipo were more effective at inhibiting the growth of cancer cells than NsLipo. Our findings suggest that LED irradiation enhances the drug delivery efficacy of liposomes and offer new possibilities for improving drug delivery systems.
    MeSH term(s) Humans ; Liposomes/chemistry ; Drug Delivery Systems ; Paclitaxel/chemistry ; Doxorubicin/chemistry ; Neoplasms/drug therapy ; Cell Line, Tumor
    Chemical Substances Liposomes ; Paclitaxel (P88XT4IS4D) ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2024-03-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 632533-6
    ISSN 1873-4995 ; 0168-3659
    ISSN (online) 1873-4995
    ISSN 0168-3659
    DOI 10.1016/j.jconrel.2024.03.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2055: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Virus-like nanoparticles as a theranostic platform for cancer.

    Kim, Kyeong Rok / Lee, Ae Sol / Kim, Su Min / Heo, Hye Ryoung / Kim, Chang Sup

    Frontiers in bioengineering and biotechnology

    2023  Volume 10, Page(s) 1106767

    Abstract: Virus-like nanoparticles (VLPs) are natural polymer-based nanomaterials that mimic viral structures through the hierarchical assembly of viral coat proteins, while lacking viral genomes. VLPs have received enormous attention in a wide range of ... ...

    Abstract Virus-like nanoparticles (VLPs) are natural polymer-based nanomaterials that mimic viral structures through the hierarchical assembly of viral coat proteins, while lacking viral genomes. VLPs have received enormous attention in a wide range of nanotechnology-based medical diagnostics and therapies, including cancer therapy, imaging, and theranostics. VLPs are biocompatible and biodegradable and have a uniform structure and controllable assembly. They can encapsulate a wide range of therapeutic and diagnostic agents, and can be genetically or chemically modified. These properties have led to sophisticated multifunctional theranostic platforms. This article reviews the current progress in developing and applying engineered VLPs for molecular imaging, drug delivery, and multifunctional theranostics in cancer research.
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.1106767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Improvement Effect of D-Chiro-Inositol and

    Yang, Hyun / Lee, Sang R / Jo, Seong Lae / Kim, Ae-Hyang / Kim, Eun-Ryoung / Qu, Fan / Hong, Eui-Ju / Lee, Hye Won

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 905191

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2022-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.905191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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