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Book ; Online: Line-of-sight gas radiation effects on near-infrared two-color ratio pyrometry measurements during plasma wind tunnel experiments

Fagnani, Andrea / Helber, Bernd / Hubin, Annick / Chazot, Olivier

2023

Abstract: Two-color ratio pyrometry is commonly used to measure the surface temperature of aerospace materials during plasma wind tunnel experiments. However, the effect of the plasma radiation on the measurement accuracy is often neglected. In this paper we ... ...

Abstract	Two-color ratio pyrometry is commonly used to measure the surface temperature of aerospace materials during plasma wind tunnel experiments. However, the effect of the plasma radiation on the measurement accuracy is often neglected. In this paper we formulate a model of the instrument response to analyze the systematic error induced by the gas radiation along the optical path. CFD simulations of the plasma flow field, together with a radiation code, allow to compute the gas spectral radiance within the instrument wavelength range. The measurement error is numerically assessed as a function of the true object temperature and emittance value. Our simulations explain the typical behavior observed in experiments, showing that a significant bias can affect the measured temperature during the material heating phase. For an actual experiment on a ceramic-matrix composite, a correction to the measured data is proposed, while comparative measurements with a spectrometer corroborate the results.
Keywords	Physics - Instrumentation and Detectors ; Physics - Fluid Dynamics ; Physics - Plasma Physics
Subject code	660
Publishing date	2023-09-29
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Operating room disinfection: operator-driven ultraviolet 'C' vs. chemical treatment.

Fickenscher, Marie-Claire / Stewart, Madeline / Helber, Ryan / Quilligan, Edward J / Kreitenberg, Arthur / Prietto, Carlos A / Gardner, Vance O

Infection prevention in practice

2023 Volume 5, Issue 3, Page(s) 100301

Abstract: Background: In operating room (OR) surfaces, Nosocomial pathogens can persist on inanimate surfaces for long intervals and are highly resistant to traditional surface cleaning.: Aim: This study compares traditional chemical operating room terminal ... ...

Abstract	Background: In operating room (OR) surfaces, Nosocomial pathogens can persist on inanimate surfaces for long intervals and are highly resistant to traditional surface cleaning. Aim: This study compares traditional chemical operating room terminal disinfection to a unique operator-driven device that emits germicidal UV light at short distance onto vertical and horizontal surfaces. Methods: A randomized crossover analogous protocol assigned 40 end-of-day operating rooms into either group A (chemical then UVC treatments) or group B (UVC then chemical treatments). Initial Staphylococcal cultures were obtained prior to disinfection treatment, after the first treatment, and after the second treatment at 16 most commonly contaminated sites to represent overall room contamination. Success was defined as no growth and failure as 1 or more colony forming units. Thoroughness of chemical treatment vs UVC treatment was compared and used to determine if the second treatment was additive to the first treatment within each group. Findings: The operator driven UVC device outperformed chemical treatment in reducing the number of contaminated sites in the OR by more than half ( Conclusions: This study demonstrates that addition of an operator-driven UVC emitter to OR rooms between cases could be helpful in overall decreasing the number of contaminated sites.
Language	English
Publishing date	2023-07-28
Publishing country	England
Document type	Journal Article
ISSN	2590-0889
ISSN (online)	2590-0889
DOI	10.1016/j.infpip.2023.100301
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Article ; Online: Rapid seagrass meadow expansion in an Indian Ocean bright spot.

Floyd, Matthew / East, Holly K / Traganos, Dimosthenis / Musthag, Azim / Guest, James / Hashim, Aminath S / Evans, Vivienne / Helber, Stephanie / Unsworth, Richard K F / Suggitt, Andrew J

Scientific reports

2024 Volume 14, Issue 1, Page(s) 10879

Abstract: The areal extent of seagrass meadows is in rapid global decline, yet they provide highly valuable societal benefits. However, their conservation is hindered by data gaps on current and historic spatial extents. Here, we outline an approach for national- ... ...

Abstract	The areal extent of seagrass meadows is in rapid global decline, yet they provide highly valuable societal benefits. However, their conservation is hindered by data gaps on current and historic spatial extents. Here, we outline an approach for national-scale seagrass mapping and monitoring using an open-source platform (Google Earth Engine) and freely available satellite data (Landsat, Sentinel-2) that can be readily applied in other countries globally. Specifically, we map contemporary (2021) and historical (2000-2021; n = 10 maps) shallow water seagrass extent across the Maldives. We found contemporary Maldivian seagrass extent was ~ 105 km
MeSH term(s)	Conservation of Natural Resources ; Indian Ocean ; Ecosystem ; Environmental Monitoring/methods ; Indian Ocean Islands
Language	English
Publishing date	2024-05-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-61088-1
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Article ; Online: Full-thickness neorectal prolapse after transanal transabdominal proctosigmoidectomy for low rectal cancer: a cohort study.

Guraieb-Trueba, M / Helber, A R / Marks, J H

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2018 Volume 20, Issue 7, Page(s) 593–596

Abstract: Aim: Transanal transabdominal proctosigmoidectomy (TATA) with a coloanal anastomosis is an alternative to abdominoperineal excision of the rectum (APR) for low rectal cancer. Neorectal prolapse is an unusual complication following TATA. This study aimed ...

Abstract	Aim: Transanal transabdominal proctosigmoidectomy (TATA) with a coloanal anastomosis is an alternative to abdominoperineal excision of the rectum (APR) for low rectal cancer. Neorectal prolapse is an unusual complication following TATA. This study aimed to determine the incidence of neorectal prolapse after TATA for low rectal cancer. Method: This cohort study was conducted in a tertiary referral colorectal centre. From a prospectively maintained database including 1093 patients treated for rectal cancer between 1984 and 2016 we identified those who underwent sphincter-preserving surgery. Data regarding the incidence, management and outcomes of neorectal prolapse were analysed. Results: A total of 409 patients were identified, of whom 185 underwent open surgery and 224 a minimally invasive surgical procedure (MIS). All received neoadjuvant chemoradiation. Neorectal prolapse occurred in 4.6% (n = 19) with an incidence of 2.2% in the open and 6.7% in the MIS group (P = 0.023), with no difference between MIS techniques. There was one recurrence of neorectal prolapse (5.9%). The incidence of neorectal prolapse was higher in women (9.5%) than men (2.5%) (P = 0.011). There were no differences in local recurrence rates between the neorectal prolapse group (5.3%) and our population without prolapse (3.4%) (P = 0.79). Conclusion: Neorectal prolapse is a rare occurrence following minimally invasive sphincter-saving surgical procedures performed for rectal cancer. It appears to be more frequent in patients who undergo MIS procedures and in women.
MeSH term(s)	Aged ; Anal Canal/surgery ; Colon, Sigmoid/surgery ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Organ Sparing Treatments/adverse effects ; Organ Sparing Treatments/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/pathology ; Proctocolectomy, Restorative/adverse effects ; Proctocolectomy, Restorative/methods ; Prospective Studies ; Rectal Neoplasms/surgery ; Rectal Prolapse/epidemiology ; Rectal Prolapse/etiology ; Rectal Prolapse/pathology ; Transanal Endoscopic Surgery/adverse effects ; Transanal Endoscopic Surgery/methods
Language	English
Publishing date	2018-01-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.14030
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Article ; Online: Cannabinoids: A Guide for Use in the World of Gastrointestinal Disease.

Unal, Ece / Anderson, Brigitte / Helber, Andrew / Marks, John H

Journal of clinical gastroenterology

2019 Volume 54, Issue 9, Page(s) 769–788

Abstract: Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, ... ...

Abstract	Cannabinoids have been known as the primary component of cannabis for decades, but the characterization of the endocannabinoid system (ECS) in the 1990s opened the doors for cannabis' use in modern medicine. The 2 main receptors of this system, cannabinoid receptors 1 and 2, are found on cells of various tissues, with significant expression in the gastrointestinal (GI) tract. The characterization of the ECS also heralded the understanding of endocannabinoids, naturally occurring compounds synthesized in the human body. Via secondary signaling pathways acting on vagal nerves, nociceptors, and immune cells, cannabinoids have been shown to have both palliative and detrimental effects on the pathophysiology of GI disorders. Although research on the effects of both endogenous and exogenous cannabinoids has been slow due to the complicated legal history of cannabis, discoveries of cannabinoids' treatment potential have been found in various fields of medicine, including the GI world. Medical cannabis has since been offered as a treatment for a myriad of conditions and malignancies, including cancer, human immunodeficiency virus/acquired immunodeficiency syndrome, multiple sclerosis, chronic pain, nausea, posttraumatic stress disorder, amyotrophic lateral sclerosis, cachexia, glaucoma, and epilepsy. This article hopes to create an overview of current research on cannabinoids and the ECS, detail the potential advantages and pitfalls of their use in GI diseases, and explore possible future developments in this field.
MeSH term(s)	Cannabinoids/adverse effects ; Cannabis ; Endocannabinoids ; Gastrointestinal Diseases/drug therapy ; Humans ; Receptors, Cannabinoid
Chemical Substances	Cannabinoids ; Endocannabinoids ; Receptors, Cannabinoid
Language	English
Publishing date	2019-11-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	448460-5
ISSN	1539-2031 ; 0192-0790
ISSN (online)	1539-2031
ISSN	0192-0790
DOI	10.1097/MCG.0000000000001287
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Article ; Online: Benthic microbial biogeographic trends in the North Sea are shaped by an interplay of environmental drivers and bottom trawling effort.

Bonthond, Guido / Beermann, Jan / Gutow, Lars / Neumann, Andreas / Barboza, Francisco Rafael / Desiderato, Andrea / Fofonova, Vera / Helber, Stephanie B / Khodami, Sahar / Kraan, Casper / Neumann, Hermann / Rohde, Sven / Schupp, Peter J

ISME communications

2023 Volume 3, Issue 1, Page(s) 132

Abstract: Microbial composition and diversity in marine sediments are shaped by environmental, biological, and anthropogenic processes operating at different scales. However, our understanding of benthic microbial biogeography remains limited. Here, we used 16S ... ...

Abstract	Microbial composition and diversity in marine sediments are shaped by environmental, biological, and anthropogenic processes operating at different scales. However, our understanding of benthic microbial biogeography remains limited. Here, we used 16S rDNA amplicon sequencing to characterize benthic microbiota in the North Sea from the top centimeter of 339 sediment samples. We utilized spatially explicit statistical models, to disentangle the effects of the different predictors, including bottom trawling intensity, a prevalent industrial fishing practice which heavily impacts benthic ecosystems. Fitted models demonstrate how the geographic interplay of different environmental and anthropogenic drivers shapes the diversity, structure and potential metabolism of benthic microbial communities. Sediment properties were the primary determinants, with diversity increasing with sediment permeability but also with mud content, highlighting different underlying processes. Additionally, diversity and structure varied with total organic matter content, temperature, bottom shear stress and bottom trawling. Changes in diversity associated with bottom trawling intensity were accompanied by shifts in predicted energy metabolism. Specifically, with increasing trawling intensity, we observed a transition toward more aerobic heterotrophic and less denitrifying predicted metabolism. Our findings provide first insights into benthic microbial biogeographic patterns on a large spatial scale and illustrate how anthropogenic activity such as bottom trawling may influence the distribution and abundances of microbes and potential metabolism at macroecological scales.
Language	English
Publishing date	2023-12-15
Publishing country	England
Document type	Journal Article
ISSN	2730-6151
ISSN (online)	2730-6151
DOI	10.1038/s43705-023-00336-3
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Article: Unusually Warm Summer Temperatures Exacerbate Population and Plant Level Response of

Helber, Stephanie B / Procaccini, Gabriele / Belshe, E Fay / Santillan-Sarmiento, Alex / Cardini, Ulisse / Bröhl, Stefanie / Schmid, Michael / Reuter, Hauke / Teichberg, Mirta

Frontiers in plant science

2021 Volume 12, Page(s) 662682

Abstract: Posidonia ... ...

Abstract	Posidonia oceanica
Language	English
Publishing date	2021-07-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2021.662682
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Article ; Online: Development of an antibody against EtpA from enterotoxigenic Escherichia coli and evaluation of its use for bacterial isolation using magnetic beads.

Astolpho, Helber A / Mariúba, Luis André M / Chaves, Yury O / Glória, Juliane C / Almeida, Maria Edilene M DE / Machado-DE-Ávila, Ricardo A / Generoso, Camille M / Batista, Jeniffer C L / Nogueira, Paulo Afonso / Orlandi, Patrícia P

Anais da Academia Brasileira de Ciencias

2024 Volume 96, Issue 2, Page(s) e20231208

Abstract: The enterotoxigenic Escherichia coli (ETEC) strain is one of the most frequent causative agents of childhood diarrhea and travelers' diarrhea in low-and middle-income countries. Among the virulence factors secreted by ETEC, the exoprotein EtpA has been ... ...

Abstract	The enterotoxigenic Escherichia coli (ETEC) strain is one of the most frequent causative agents of childhood diarrhea and travelers' diarrhea in low-and middle-income countries. Among the virulence factors secreted by ETEC, the exoprotein EtpA has been described as an important. In the present study, a new detection tool for enterotoxigenic E. coli bacteria using the EtpA protein was developed. Initially, antigenic sequences of the EtpA protein were selected via in silico prediction. A chimeric recombinant protein, corresponding to the selected regions, was expressed in an E. coli host, purified and used for the immunization of mice. The specific recognition of anti-EtpA IgG antibodies generated was evaluated using flow cytometry. The tests demonstrated that the antibodiesdeveloped were able to recognize the native EtpA protein. By coupling these antibodies to magnetic beads for the capture and detection of ETEC isolates, cytometric analyses showed an increase in sensitivity, specificity and the effectiveness of the method of separation and detection of these pathogens. This is the first report of the use of this methodology for ETEC separation. Future trials may indicate their potential use for isolating these and other pathogens in clinical samples, thus accelerating the diagnosis and treatment of diseases.
MeSH term(s)	Enterotoxigenic Escherichia coli/immunology ; Animals ; Mice ; Flow Cytometry/methods ; Escherichia coli Proteins/immunology ; Antibodies, Bacterial/immunology ; Sensitivity and Specificity ; Mice, Inbred BALB C ; Female ; Immunoglobulin G/immunology
Language	English
Publishing date	2024-05-13
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2046885-4
ISSN	1678-2690 ; 0001-3765
ISSN (online)	1678-2690
ISSN	0001-3765
DOI	10.1590/0001-3765202420231208
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Article ; Online: Assessment of yield performance and stability of hybrids and populations of tropical maize across multiple environments in Southeastern Brazil

Uberti, Alison / Rezende, Wemerson Mendonça / Caixeta, Diego Gonçalves / Reis, Helber Moreira / Resende, Nathalia Campos Vilela / Destro, Vidomar / DeLima, Rodrigo Oliveira

Crop Science. 2023 , v. 63, no. 4 p.2012-2032

2023

Abstract: The identification of stable genotypes with high yield in diverse multiple‐stress environments is important to increase maize (Zea mays L.) grain yield under tropical environments. Our objective was to assess the yield performance and stability of ... ...

Abstract	The identification of stable genotypes with high yield in diverse multiple‐stress environments is important to increase maize (Zea mays L.) grain yield under tropical environments. Our objective was to assess the yield performance and stability of experimental hybrids and broad‐based populations of tropical maize across diverse environments in Southeastern Brazil. We evaluated two sets of maize genotypes for grain yield: 190 experimental hybrids along with 6 commercial hybrids and 45 population hybrids along with their 10 parental populations across 8 environments in Southeastern Brazil. Multiple statistical methods were used and compared in the analyses. Combined analysis of variance indicated that genotypic main effect (G), environmental main effect (E), and genotype by environment interaction were highly significant (p < 0.0001) for grain yield. The E accounted for 42% of the total variation for both hybrids and populations, and they were more similar within the growing season than between seasons, mainly for populations. Low nitrogen (N) stress was a key factor in hybrid evaluation and recommendation, particularly under drought stress conditions. Among the environment classification methods, genotype main effect plus genotype × environment interaction (GGE) biplot provided more accurate information about environments grouping and selection of the genotypes than the Eberhart and Russell method. Harmonic mean of the relative performance of the predicted genetic values (HMRPGV) based on mixed models ranked the hybrids and populations according to mean grain yield and stability, penalizing hybrids, and populations with lower stability. Therefore, we recommend the GGE biplot and HMRPGV for genotype evaluation based on multi‐environment trials data. These methods identified 92V2144 and 92V2033 as the most promising hybrids for favorable and 92V2141, 92V2153, and 92V2137 as the most promising for unfavorable environments. 92VX033 and 92VX043 were identified as broadly adapted and stable populations across multiple environments in Southeastern Brazil.
Keywords	Zea mays ; analysis of variance ; corn ; genotype ; genotype-environment interaction ; grain yield ; hybrids ; nitrogen ; water stress ; Brazil
Language	English
Dates of publication	2023-07
Size	p. 2012-2032.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	410209-5
ISSN	0011-183X
ISSN	0011-183X
DOI	10.1002/csc2.20964
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Langzeitevaluation der Implementierung des Safewards-Modells – Ergebnisse einer Follow-Up-Erhebung unter Patient*innen und Mitarbeitenden der Akutpsychiatrie.

Al-Wandi, Mohammed S I / Baumgardt, Johanna / Jäckel, Dorothea / Helber-Böhlen, Heike / Voigt, Andre / Mc Cutcheon, Ann-Kathrin / Schöppe, Enrico / Lecca, Edwin Emilio Velasquez / Löhr, Michael / Schulz, Michael / Weinmann, Stefan / Bechdolf, Andreas

Psychiatrische Praxis

2022 Volume 50, Issue 2, Page(s) 98–102

Abstract: Objective: Evaluation of long-term effects of the implementation of the Safewards Model (SM) among staff and patients in acute psychiatry in Germany.: Method: Assessment of ward atmosphere, job satisfaction, fidelity, and coercive interventions in 2 ... ...

Title translation	Long Term Evaluation of the Implementation of the Safewards Model - Results of a Follow-Up-Study Among Patients and Staff in Acute Psychiatric Wards.
Abstract	Objective: Evaluation of long-term effects of the implementation of the Safewards Model (SM) among staff and patients in acute psychiatry in Germany. Method: Assessment of ward atmosphere, job satisfaction, fidelity, and coercive interventions in 2 locked wards directly before and 15 months after implementation of the SM. Results: Ward atmosphere was assessed significantly better after implementation, job satisfaction was still above-average at both times, coercive interventions declined significantly in one ward, fidelity and degree of implementation were still high. Conclusions: The implementing of the SM in locked wards in acute psychiatry can also have positive effects in long run.
MeSH term(s)	Humans ; Psychiatric Department, Hospital ; Follow-Up Studies ; Germany ; Coercion ; Psychiatry
Language	German
Publishing date	2022-12-01
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	124981-2
ISSN	1439-0876 ; 0303-4259
ISSN (online)	1439-0876
ISSN	0303-4259
DOI	10.1055/a-1961-1486
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