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  1. Article ; Online: Identifying an elusive target with the help of an unproven technique.

    Weiser, Mark / Davidson, Michael

    Molecular psychiatry

    2021  Volume 26, Issue 12, Page(s) 7074–7075

    MeSH term(s) Humans ; Psychiatry
    Language English
    Publishing date 2021-07-10
    Publishing country England
    Document type News
    ZDB-ID 1330655-8
    ISSN 1476-5578 ; 1359-4184
    ISSN (online) 1476-5578
    ISSN 1359-4184
    DOI 10.1038/s41380-021-01213-y
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    Zs.A 4812: Show issues Location:
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  2. Article ; Online: Breaking Up Isn't Hard to Do: Isolating Cell-free DNA Fragments in Osteosarcoma.

    Weiser, Daniel A / Hayashi, Masanori / Applebaum, Mark A

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2023  Volume 29, Issue 11, Page(s) 2017–2019

    Abstract: The novel use of blood-based biospecimens from a retrospective cohort of 50 patients with osteosarcoma was recently studied. The potential clinical utility of sorting cell-free DNA by fragment size was defined, with shorter tumor-specific DNA enrichment ... ...

    Abstract The novel use of blood-based biospecimens from a retrospective cohort of 50 patients with osteosarcoma was recently studied. The potential clinical utility of sorting cell-free DNA by fragment size was defined, with shorter tumor-specific DNA enrichment providing prognostic value and allowing for streamlined molecular profiling of circulating tumor material. See related article by Udomruk et al., p. 2085.
    MeSH term(s) Humans ; Cell-Free Nucleic Acids/genetics ; Retrospective Studies ; Prognosis ; DNA, Neoplasm/genetics ; Osteosarcoma/diagnosis ; Osteosarcoma/genetics ; Osteosarcoma/therapy ; Bone Neoplasms/diagnosis ; Bone Neoplasms/genetics
    Chemical Substances Cell-Free Nucleic Acids ; DNA, Neoplasm
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-23-0390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4223: Show issues Location:
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  3. Article: Prevention of Post-traumatic stress disorder by Early Psychological Interventions in Israel Following the October 7th Massacre.

    Nacasch, Nitsa / Shoenfeld, Netta / Wul, Ilanit / Polliack, Michael / Weiser, Mark

    The Israel Medical Association journal : IMAJ

    2023  Volume 25, Issue 11, Page(s) 724–728

    MeSH term(s) Humans ; Stress Disorders, Post-Traumatic/prevention & control ; Stress Disorders, Post-Traumatic/psychology ; Psychosocial Intervention ; Israel/epidemiology ; Cognitive Behavioral Therapy ; Stress, Psychological
    Language English
    Publishing date 2023-11-18
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
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    Zs.A 5470: Show issues Location:
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  4. Article ; Online: The adventitia in arterial development, remodeling, and hypertension.

    Majesky, Mark W / Weiser-Evans, Mary C M

    Biochemical pharmacology

    2022  Volume 205, Page(s) 115259

    Abstract: The adventitia receives input signals from the vessel wall, the immune system, perivascular nerves and from surrounding tissues to generate effector responses that regulate structural and mechanical properties of blood vessels. It is a complex and ... ...

    Abstract The adventitia receives input signals from the vessel wall, the immune system, perivascular nerves and from surrounding tissues to generate effector responses that regulate structural and mechanical properties of blood vessels. It is a complex and dynamic tissue that orchestrates multiple functions for vascular development, homeostasis, repair, and disease. The purpose of this review is to highlight recent advances in our understanding of the origins, phenotypes, and functions of adventitial and perivascular cells with particular emphasis on hypertensive vascular remodeling.
    MeSH term(s) Humans ; Adventitia/physiology ; Arteries ; Hypertension
    Language English
    Publishing date 2022-09-21
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2022.115259
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    Zs.A 19: Show issues Location:
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  5. Article ; Online: Development of the Therapeutic Alliance in Alternative Settings to Psychiatric Hospitalization: An Open Comparative Study.

    Friedlander, Avraham / Sinai, Dana / Zilcha-Mano, Sigal / Weiser, Mark / Caspi, Asaf / Lichtenberg, Pesach / Amitai, Ziv / Tzur Bitan, Dana

    Psychiatric services (Washington, D.C.)

    2024  , Page(s) appips20230009

    Abstract: Patient-therapist alliance in two alternative treatment settings developed similarly to that in traditional psychiatric hospitalization. ...

    Abstract Patient-therapist alliance in two alternative treatment settings developed similarly to that in traditional psychiatric hospitalization.
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220173-x
    ISSN 1557-9700 ; 1075-2730
    ISSN (online) 1557-9700
    ISSN 1075-2730
    DOI 10.1176/appi.ps.20230009
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    Zs.A 416: Show issues Location:
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  6. Article ; Online: Insights into metabolic dysregulations associated with antipsychotics.

    Domany, Yoav / Weiser, Mark

    The lancet. Psychiatry

    2019  Volume 7, Issue 1, Page(s) 6–7

    MeSH term(s) Antipsychotic Agents ; Humans ; Network Meta-Analysis ; Schizophrenia ; Weight Gain/drug effects
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2019-12-17
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(19)30473-0
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  7. Article ; Online: Long-term effects of Roluperidone on negative symptoms of schizophrenia.

    Rabinowitz, Jonathan / Staner, Corinne / Saoud, Jay / Weiser, Mark / Kuchibhatla, Ramana / Davidson, Michael / Harvey, Phillip D / Luthringer, Remy

    Schizophrenia research

    2023  Volume 255, Page(s) 9–13

    Abstract: Roluperidone has antagonist properties for 5- ... ...

    Abstract Roluperidone has antagonist properties for 5-HT
    MeSH term(s) Humans ; Treatment Outcome ; Schizophrenia/diagnosis ; Antipsychotic Agents/adverse effects ; Indoles/therapeutic use ; Double-Blind Method ; Randomized Controlled Trials as Topic
    Chemical Substances roluperidone (4P31I0M3BF) ; Antipsychotic Agents ; Indoles
    Language English
    Publishing date 2023-03-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2023.03.028
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    Zs.A 2351: Show issues Location:
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    Zs.MO 543: Show issues

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  8. Article: Three Cases of COVID-19-related First Onset Brief Reactive Psychosis.

    Jaworowski, Sol / Weiser, Mark / Gropp, Cornelius / Malka, Moria

    The Israel Medical Association journal : IMAJ

    2020  Volume 22, Issue 10, Page(s) 612

    MeSH term(s) Adult ; Antipsychotic Agents/administration & dosage ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Coronavirus Infections/psychology ; Coronavirus Infections/therapy ; Delusions/diagnosis ; Haloperidol/administration & dosage ; Humans ; Involuntary Treatment ; Lorazepam/administration & dosage ; Male ; Olanzapine/administration & dosage ; Pandemics/prevention & control ; Paranoid Behavior/diagnosis ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/psychology ; Pneumonia, Viral/therapy ; Psychotic Disorders/diagnosis ; Psychotic Disorders/drug therapy ; Psychotic Disorders/etiology ; SARS-CoV-2 ; Social Isolation/psychology ; Treatment Outcome
    Chemical Substances Antipsychotic Agents ; Haloperidol (J6292F8L3D) ; Olanzapine (N7U69T4SZR) ; Lorazepam (O26FZP769L)
    Keywords covid19
    Language English
    Publishing date 2020-10-24
    Publishing country Israel
    Document type Case Reports ; Journal Article
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
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  9. Article ; Online: Early intervention for schizophrenia: the risk-benefit ratio of antipsychotic treatment in the prodromal phase.

    Weiser, Mark

    The American journal of psychiatry

    2011  Volume 168, Issue 8, Page(s) 761–763

    MeSH term(s) Antipsychotic Agents/administration & dosage ; Disease Progression ; Early Diagnosis ; Humans ; Longitudinal Studies ; Schizophrenia/diagnosis ; Schizophrenia/drug therapy ; Schizophrenic Psychology ; Schizotypal Personality Disorder/diagnosis ; Schizotypal Personality Disorder/drug therapy ; Schizotypal Personality Disorder/psychology ; Treatment Outcome
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2011-08
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2011.11050765
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  10. Article ; Online: Can Quetiapine Prolong the Antidepressant Effect of Ketamine?: A 5-Year Follow-up Study.

    Amiaz, Revital / Saporta, Rachel / Noy, Adam / Berkenstadt, Haim / Weiser, Mark

    Journal of clinical psychopharmacology

    2021  Volume 41, Issue 6, Page(s) 673–675

    Abstract: Purpose: Ketamine, a noncompetitive, high-affinity antagonist of the N-methyl-d-aspartate-type glutamate receptor, has a rapid effect in patients with treatment-resistant disorder, but many patients who respond to intravenous ketamine relapse within ... ...

    Abstract Purpose: Ketamine, a noncompetitive, high-affinity antagonist of the N-methyl-d-aspartate-type glutamate receptor, has a rapid effect in patients with treatment-resistant disorder, but many patients who respond to intravenous ketamine relapse within several days. The objective of this study was to examine the long-term outcome of patients' mood 5 years after ketamine treatment.
    Methods: Sixteen electroconvulsive therapy referrals received at least 1 intravenous ketamine treatment in addition to their stable antidepressant medications. Depression was evaluated using the Inventory of Depressive Symptomatology-Clinician-Rated, Hamilton Rating Scales for Depression, and Montgomery-Åsberg Depression Rating Scale. Anxiety was measured using the Hamilton Rating Scale.
    Results: Of 16 patients treated, 6 achieved complete remission, 3 partially responded, and 7 did not respond. At baseline, all patients were treated with antidepressants, 14 patients were also treated with neuroleptics, of whom 5 patients were treated with quetiapine. The time to relapse in the 5 patients taking quetiapine was significantly longer than in patients who were taking other neuroleptics (965.83 ± 824.68 vs 80.5 ± 114.3, Z = 7.001, P = 0.0001). At the 5-year follow-up, 3 of the patients taking quetiapine maintained their remission. Overall levels of depression and anxiety at all times were improved in comparison to baseline.
    Conclusions: Our follow-up results suggest that the combination of quetiapine and ketamine can prolong time to relapse after ketamine treatment in patients with treatment-resistant disorder.
    MeSH term(s) Adult ; Antidepressive Agents/administration & dosage ; Antidepressive Agents/pharmacology ; Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/pharmacology ; Depressive Disorder, Treatment-Resistant/drug therapy ; Drug Therapy, Combination ; Female ; Follow-Up Studies ; Humans ; Ketamine/administration & dosage ; Ketamine/pharmacology ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Quetiapine Fumarate/administration & dosage ; Quetiapine Fumarate/pharmacology ; Remission Induction ; Secondary Prevention
    Chemical Substances Antidepressive Agents ; Antipsychotic Agents ; Quetiapine Fumarate (2S3PL1B6UJ) ; Ketamine (690G0D6V8H)
    Language English
    Publishing date 2021-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000001489
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