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  1. Article ; Online: Myocardial work and takotsubo syndrome: stress affects work.

    Vitarelli, Antonio

    The international journal of cardiovascular imaging

    2022  Volume 38, Issue 8, Page(s) 1807–1812

    MeSH term(s) Humans ; Takotsubo Cardiomyopathy/diagnostic imaging ; Predictive Value of Tests ; Myocardium
    Language English
    Publishing date 2022-06-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-022-02655-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Myocardial strain and refractory angina: an intriguing puzzle.

    Vitarelli, Antonio

    The international journal of cardiovascular imaging

    2021  Volume 37, Issue 8, Page(s) 2491–2495

    MeSH term(s) Angina Pectoris ; Humans ; Myocardium ; Predictive Value of Tests
    Language English
    Publishing date 2021-07-02
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-021-02310-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Myocardial strain impairment, heterozygous familial hypercholesterolemia and systemic arterial hypertension: Is there a link?

    Vitarelli, Antonio

    International Journal of Cardiology. Hypertension

    2021  Volume 9, Page(s) 100086

    Abstract: Dyslipidemia is known as a strong risk factor for premature atherosclerotic cardiovascular disease and increased morbidity and mortality and can have an adverse effect on left ventricular function due to direct or indirect macrovascular and/or ... ...

    Abstract Dyslipidemia is known as a strong risk factor for premature atherosclerotic cardiovascular disease and increased morbidity and mortality and can have an adverse effect on left ventricular function due to direct or indirect macrovascular and/or microvascular damage. Speckle-tracking echocardiography allows the assessment of subclinical cardiac dysfunction in different diseases on the basis of myocardial deformation indices, and decrease in longitudinal and circumferential strain was shown in patients with heterozygous familial hypercholesterolemia (heFH) without comorbidities. In this issue of the journal a new study presents the results in a well-defined population which included asymptomatic treatment-naive heFH individuals without known coronary/peripheral arterial disease, with normal left ventricular ejection fraction and no other risk factors as formal arterial hypertension or diabetes mellitus. A slight impairment of global longitudinal strain was present, despite normal standard echocardiographic parameters. Also, the higher rise in systolic and diastolic blood pressure of heHF patients during exercise treadmill test might reflect early preclinical hypertension. High cholesterol level may have produced endothelial dysfunction, which has been shown to be related to the extent of atherosclerotic process and cardiovascular damage. Relevant findings are reported on left ventricular strain reduction and increase in systolic/diastolic blood pressure in asymptomatic heFH males. The relationship between myocardial strain impairment and developing systemic arterial hypertension in hypercholesterolemic patients could be the subject of further subsequent investigation.
    Language English
    Publishing date 2021-05-11
    Publishing country Netherlands
    Document type Editorial
    ISSN 2590-0862
    ISSN (online) 2590-0862
    DOI 10.1016/j.ijchy.2021.100086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Patent Foramen Ovale: Pivotal Role of Transesophageal Echocardiography in the Indications for Closure, Assessment of Varying Anatomies and Post-procedure Follow-up.

    Vitarelli, Antonio

    Ultrasound in medicine & biology

    2019  Volume 45, Issue 8, Page(s) 1882–1895

    Abstract: Patent foramen ovale (PFO) is present in 15%-30% of the general population and has been associated with various pathologic states, including cryptogenic stroke, platypnea-orthodeoxia syndrome, decompression sickness and migraine with auras. ... ...

    Abstract Patent foramen ovale (PFO) is present in 15%-30% of the general population and has been associated with various pathologic states, including cryptogenic stroke, platypnea-orthodeoxia syndrome, decompression sickness and migraine with auras. Transesophageal echocardiography (TEE) has a major role in the diagnostic evaluation of PFO, as well as in the post-procedural assessment after transcatheter closure. The goals of this article were to synthesize the echocardiographic transesophageal techniques required for accurate PFO diagnosis and careful anatomic assessment of its anatomic variants, to focus TEE indications for device closure as complementary to clinical indications and to assess the role of TEE in the post-procedure follow-up.
    MeSH term(s) Echocardiography, Transesophageal/methods ; Follow-Up Studies ; Foramen Ovale/anatomy & histology ; Foramen Ovale/diagnostic imaging ; Foramen Ovale/surgery ; Foramen Ovale, Patent/diagnostic imaging ; Foramen Ovale, Patent/surgery ; Humans
    Language English
    Publishing date 2019-05-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2019.04.015
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  5. Article ; Online: A Novel Index of Right Ventriculoarterial Coupling in Adult Patients With Repaired Tetralogy of Fallot Using Three-Dimensional Speckle-Tracking Echocardiography.

    Vitarelli, Antonio / Capotosto, Lidia / Mangieri, Enrico / Tanzilli, Gaetano / Viceconte, Nicola / Miraldi, Fabio

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2022  Volume 36, Issue 3, Page(s) 341–343

    MeSH term(s) Humans ; Adult ; Tetralogy of Fallot/surgery ; Echocardiography/methods ; Heart Ventricles/diagnostic imaging ; Ventricular Function, Right ; Ventricular Dysfunction, Right
    Language English
    Publishing date 2022-11-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2022.11.008
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  6. Article ; Online: Echocardiography, troponins and lower extremity ultrasound: the 'Three Musketeers' lead the prognosis of acute pulmonary embolism.

    Vitarelli, Antonio

    Thorax

    2011  Volume 66, Issue 1, Page(s) 2–4

    MeSH term(s) Acute Disease ; Biomarkers/blood ; Humans ; Prognosis ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/diagnostic imaging ; Troponin I/blood ; Ultrasonography ; Venous Thrombosis/diagnostic imaging
    Chemical Substances Biomarkers ; Troponin I
    Language English
    Publishing date 2011-01
    Publishing country England
    Document type Editorial
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thx.2010.151316
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  7. Article: Intermediate-term oncological and functional outcomes in prostate cancer patients treated with perineal robot-assisted radical prostatectomy: A single center analysis.

    Carbonara, Umberto / Lippolis, Giuseppe / Rella, Luciano / Minafra, Paolo / Guglielmi, Giuseppe / Vitarelli, Antonio / Lucarelli, Giuseppe / Ditonno, Pasquale

    Asian journal of urology

    2023  Volume 10, Issue 4, Page(s) 423–430

    Abstract: Objective: In the last 10 years, robotic platforms allowed to resume of some alternative surgical approaches, including perineal robot-assisted radical prostatectomy (p-RARP). Herein, we present in detail the oncological and functional outcomes of ... ...

    Abstract Objective: In the last 10 years, robotic platforms allowed to resume of some alternative surgical approaches, including perineal robot-assisted radical prostatectomy (p-RARP). Herein, we present in detail the oncological and functional outcomes of patients who underwent p-RARP with a median follow-up of 30 months.
    Methods: Patients presenting low- or intermediate-risk prostate cancer and prostate volume up to 60 mL who underwent p-RARP between November 2018 and November 2022 were selected. Baseline, intraoperative, pathological, and postoperative data were collected and then analyzed.
    Results: Thirty-seven p-RARP cases were included. Such patients presented mean age of 62 years and a mean Charlson comorbidity index of 4. Body mass index of ≥25 kg/m
    Conclusion: p-RARP is a challenging but safe minimally invasive approach for selected patients with prostate cancer suitable for radical prostatectomy, showing outstanding functional recovery. Despite positive surgical margin rates being relatively high, no cases of biochemical recurrence or distant metastasis were reported after a median follow-up of 30 months.
    Language English
    Publishing date 2023-08-19
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2831144-9
    ISSN 2214-3882
    ISSN 2214-3882
    DOI 10.1016/j.ajur.2023.05.005
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  8. Article ; Online: Xi Nerve-sparing Robotic Radical Perineal Prostatectomy: European Single-center Technique and Outcomes.

    Carbonara, Umberto / Minafra, Paolo / Papapicco, Giuseppe / De Rienzo, Gaetano / Pagliarulo, Vincenzo / Lucarelli, Giuseppe / Vitarelli, Antonio / Ditonno, Pasquale

    European urology open science

    2022  Volume 41, Page(s) 55–62

    Abstract: Background: Radical prostatectomy (RP) represents the standard of care for the treatment of patients with organ-confined prostatic cancer. Historically, perineal RP has been described as the first surgical approach for the complete removal of the ... ...

    Abstract Background: Radical prostatectomy (RP) represents the standard of care for the treatment of patients with organ-confined prostatic cancer. Historically, perineal RP has been described as the first surgical approach for the complete removal of the prostatic gland. In the past years, robotic techniques provided some technical advantages that allow resuming alternative approaches, such as robotic radical perineal prostatectomy (r-RPP).
    Objective: To present in detail the technique of Xi nerve-sparing r-RPP and to report perioperative, oncological, and functional outcomes from a European tertiary center.
    Design setting and participants: Patients with low- or intermediate-risk prostatic cancer not suitable for active surveillance and prostate volume up to 60 ml who underwent r-RPP between November 2018 and December 2020 were identified.
    Surgical procedure: All patients underwent Xi nerve-sparing r-RPP.
    Measurements: Baseline characteristics and intraoperative, pathological, and postoperative data were collected and analyzed. The complications were reported according to the standardized methodology to report complications proposed by European Association of Urology guidelines.
    Results and limitations: Overall, our series included 26 patients who underwent r-RPP. Patients' median age was 62.5 yr. Thirteen (50%) and eight (30.7%) patients showed a body mass index (BMI) of 25-30 and >30, respectively. A history of past surgical procedures was present in seven (26.8%) patients. The median prostate volume was 40 (interquartile range [IQR]: 28-52) ml. The median operative time and blood lost were 246 (IQR: 230-268) min and 275 (IQR: 200-400) ml, respectively. Overall, four (15.4%) patients reported intraoperative complications and five (19.2%) reported postoperative complications, with one (3.8%) reporting major complications (Clavien-Dindo ≥3). No patient with biochemical recurrence (BCR) was reported at 1 yr of follow-up. Continence rates were 73.0%, 84.6%, and 92.3%, respectively, at 3, 6, and 12 mo after surgery. Erectile potency recovery rates were 57.1%, 66.6%, and 80.9% at 3, 6, and 12 mo of follow-up, respectively.
    Conclusions: Xi r-RPP is a challenging but safe minimally invasive approach for selected patients. No patient reported BCR at 12 mo. The choice of the surgical approach for RP is likely to be based on the patient's characteristics as well as the surgeon's preferences.
    Patient summary: Our study suggests that Xi radical perineal prostatectomy is a safe minimally invasive approach for patients with low- or intermediate-risk prostatic cancer, and complex abdominal surgical history or comorbidities.
    Language English
    Publishing date 2022-05-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3040546-4
    ISSN 2666-1683 ; 2058-4881
    ISSN (online) 2666-1683
    ISSN 2058-4881
    DOI 10.1016/j.euros.2022.04.014
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  9. Article ; Online: Peculiar clinical and diagnostic features of infective endocarditis in Yemen: Comparative analysis with a Western University Hospital.

    Al-Kebsi, Mohammed / Al-Motarreb, Ahmed / Al-Kadasi, Huda / Al-Muqayad, Mohammad Hussain / Mangieri, Enrico / Capotosto, Lidia / Miraldi, Fabio / Mastroianni, Claudio / Vitarelli, Antonio

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    2023  Volume 71, Issue 2, Page(s) 132–139

    Abstract: The aim of this study was to describe the pattern, characteristics, and outcomes of infective endocarditis (IE) in Yemen and compare the results with the findings of a Western university hospital. Patients (pts) with a final diagnosis of IE observed in ... ...

    Abstract The aim of this study was to describe the pattern, characteristics, and outcomes of infective endocarditis (IE) in Yemen and compare the results with the findings of a Western university hospital. Patients (pts) with a final diagnosis of IE observed in Al-Thawra Sanaa Cardiac Center were prospectively enrolled in 1-year time period. Clinical and diagnostic findings were compared to clinical and diagnostic data of 50 pts with IE observed at Sapienza University Hospital in Rome, Italy. The mean age was 38 ± 6. Predisposing factors for IE were rheumatic heart disease (RHD) in 34 pts (68%), congenital heart disease in 9 pts (18%), prosthetic valve IE in 4 pts (8%), and previous IE in 3 pts (6%). Transthoracic echocardiography (TTE) was done in 50 pts and transesophageal echocardiography (TEE) in 25. Blood cultures were taken in all pts and were positive in 3 pts (6%) and negative in 47 (94%). TTE was positive in 34/50 pts (68%) and TEE in 20/25 (80%). Compared to Sapienza University pts, Al-Thawra Cardiac Center pts had a younger age (p = 0.003), more predisposing RHD (p = 0.0004), less prosthetic heart valves IE (p = 0.002), and more negative blood cultures (p = 0.0001). IE is still a common disease in Yemen among RHD pts and affects the younger age group. It has severe complications which need early diagnosis and proper management. Echocardiography is of prime diagnostic value in the absence of positive blood cultures. An effort should be made to prevent rheumatic fever and RHD.
    MeSH term(s) Humans ; Adult ; Yemen/epidemiology ; Endocarditis, Bacterial ; Endocarditis/diagnostic imaging ; Echocardiography/methods ; Hospitals ; Retrospective Studies
    Language English
    Publishing date 2023-01-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 0009-9279 ; 1081-5589
    ISSN (online) 1708-8267
    ISSN 0009-9279 ; 1081-5589
    DOI 10.1177/10815589221143327
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  10. Article ; Online: Heart, COVID-19, and echocardiography.

    Capotosto, Lidia / Nguyen, Bich Lien / Ciardi, Maria Rosaria / Mastroianni, Claudio / Vitarelli, Antonio

    Echocardiography (Mount Kisco, N.Y.)

    2020  Volume 37, Issue 9, Page(s) 1454–1464

    Abstract: Although clinical manifestations of coronavirus disease of 2019 (COVID-19) mainly consist of respiratory symptoms, a severe cardiovascular damage may occur. Moreover, previous studies reported a correlation of cardiovascular metabolic diseases with ... ...

    Abstract Although clinical manifestations of coronavirus disease of 2019 (COVID-19) mainly consist of respiratory symptoms, a severe cardiovascular damage may occur. Moreover, previous studies reported a correlation of cardiovascular metabolic diseases with severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and actually, many COVID-19 patients show comorbidities (systemic hypertension, cardio-cerebrovascular disease, and diabetes) and have a raised risk of death. The purpose of this review is to focus the cardiovascular effects of 2019-nCoV on the base of the most recent specific literature and previous learnings from SARS and MERS and analyze the potential role of echocardiography during the current critical period and short- and long-term follow-up.
    MeSH term(s) COVID-19/complications ; COVID-19/physiopathology ; Echocardiography/methods ; Heart/diagnostic imaging ; Heart/physiopathology ; Heart Diseases/diagnostic imaging ; Heart Diseases/etiology ; Heart Diseases/physiopathology ; Humans
    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 843645-9
    ISSN 1540-8175 ; 0742-2822
    ISSN (online) 1540-8175
    ISSN 0742-2822
    DOI 10.1111/echo.14834
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