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Article ; Online: Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit.

Moneme, Chioma / Kausch, Sherry L / Belmonte, Briana M / Fleming Ii, Mark A / Levin, Daniel E / Sullivan, Brynne A

2024

Abstract: Objective: Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics (HRCs) such as ... ...

Abstract	Objective: Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics (HRCs) such as decreased variability occur due to the inflammatory response to sepsis in preterm infants. This study aimed to test the hypothesis that infants with gastroschisis have decreased heart rate variability (HRV) after birth and that this physiomarker may predict outcomes. Study design: We analyzed heart rate data from and clinical variables for all infants admitted with gastroschisis from 2009 to 2020. Results: Forty-seven infants were admitted during the study period and had available data. Complex gastroschisis infants had reduced HRV after birth. For those with sepsis and necrotizing enterocolitis, abnormal HRCs occurred early in the course of illness. Conclusion: Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on total parenteral nutrition. Key points: · Infants with gastroschisis can be classified into two subcategories, simple and complex disease.. · Those with complex disease often require prolonged stays in the neonatal intensive care unit and costly hospitalizations. We hypothesized that infants with complex gastroschisis are more likely to have abnormal HRC due to intestinal inflammation.. · In this study, we identified associations between abnormal HRV, heart rate characteristicHRC, and the development of gastroschisis complications. Additionally, we described differences in clinical characteristics between infants with complex versus simple gastroschisis..
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/a-2244-0148
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Article ; Online: Trends in outcomes following aseptic revision shoulder arthroplasty.

Stauffer, Taylor P / Goltz, Daniel E / Wickman, John R / Levin, Jay M / Lassiter, Tally E / Anakwenze, Oke A / Klifto, Christopher S

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

2023 Volume 33, Issue 7, Page(s) 3025–3031

Abstract: Purpose: As the incidence of anatomic and reverse total shoulder arthroplasty (TSA, RSA) increases, revision procedures will also increase with a corresponding need for counseling patients regarding outcomes. We hypothesized that different revision ... ...

Abstract	Purpose: As the incidence of anatomic and reverse total shoulder arthroplasty (TSA, RSA) increases, revision procedures will also increase with a corresponding need for counseling patients regarding outcomes. We hypothesized that different revision categories would have different complication profiles depending on both the indication as well as the nature of the prior hardware. Methods: A retrospective review of 1773 cases performed at a single tertiary health system utilized case postings and diagnoses to identify revision shoulder arthroplasty cases. Revisions were classified based on the prior hardware present, with basic demographics and other perioperative and postoperative outcomes recorded within the limits of available follow-up. Results: 166 surgical cases involving revision of prior shoulder arthroplasty metal hardware were identified with an average follow-up of 1.0 years. Immediate perioperative outcomes of revision cases were similar relative to the companion cohort of 1607 primary cases. 137 cases (83%) required no further revision surgery, while 19 cases (11%) underwent aseptic revision, and 10 cases (6%) were revised for periprosthetic infection. RSA hardware revised to another RSA had the highest repeat revision rate relative to the other revision categories (32% vs < 14%). Conclusions: Revision of reverse shoulder arthroplasty to a repeat reverse has the highest rate of subsequent all-cause revision, and these repeat revisions often occurred for periprosthetic infection. Despite a relatively high long-term complication rate following revision shoulder arthroplasty, immediate perioperative outcomes remain similar to primary cases, providing some preliminary evidence for policymakers considering inclusion in future value-based care models. Level of evidence: Level III Treatment Study.
MeSH term(s)	Humans ; Arthroplasty, Replacement, Shoulder/adverse effects ; Arthroplasty, Replacement, Shoulder/methods ; Shoulder Joint/surgery ; Treatment Outcome ; Reoperation ; Retrospective Studies
Language	English
Publishing date	2023-03-25
Publishing country	France
Document type	Journal Article
ZDB-ID	1231084-0
ISSN	1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
ISSN (online)	1432-1068
ISSN	1633-8065 ; 0948-4817 ; 0940-3264
DOI	10.1007/s00590-023-03524-y
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Zs.A 3479: Show issues

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Article: Transitioning to Outpatient Shoulder Arthroplasty: Safety, Efficiency, and Cost in a Diverse Payer Mix.

Goltz, Daniel E / Levin, Jay M / Wickman, John R / O'Donnell, Jeffrey A / Sugarman, Barrie S / Wixted, Colleen M / Wittstein, Jocelyn R / Lassiter, Tally E

Journal of surgical orthopaedic advances

2024 Volume 32, Issue 4, Page(s) 263–269

Abstract: Outpatient shoulder arthroplasty presents potential clinical benefits but also risk without perioperative optimization. Length of stay depends largely on surgeon preferences, and a large single-surgeon cohort may provide insight into optimal strategies ... ...

Abstract	Outpatient shoulder arthroplasty presents potential clinical benefits but also risk without perioperative optimization. Length of stay depends largely on surgeon preferences, and a large single-surgeon cohort may provide insight into optimal strategies and costs for outpatient shoulder arthroplasty. A single-surgeon cohort of 472 anatomic and reverse shoulder arthroplasties performed between 2017 and 2020 was retrospectively reviewed. Cases were stratified by those who did or did not undergo same-day discharge. The 90-day readmission, discharge to post-acute care, cost, and 45 patient/case factors were examined. Two hundred fifty (53%) underwent same-day discharge, with the proportion of outpatient cases increasing over time to nearly 80%, with no significant difference in 90-day readmissions. Revision cases often underwent same-day discharge, whereas fractures were typically admitted. The cost was significantly higher for inpatients, with implants accounting for 52%. Surgeons may safely transition a substantial proportion of shoulder arthroplasties to same-day discharge with some reassurance regarding cost savings and 90-day readmissions. (Journal of Surgical Orthopaedic Advances 32(4):263-269, 2023).
MeSH term(s)	Humans ; Arthroplasty, Replacement, Shoulder ; Retrospective Studies ; Outpatients ; Arthroplasty ; Hospitalization ; Patient Readmission ; Postoperative Complications
Language	English
Publishing date	2024-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2189157-6
ISSN	2158-3811 ; 1548-825X ; 1059-1052
ISSN (online)	2158-3811
ISSN	1548-825X ; 1059-1052
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Zs.A 4751: Show issues

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Article ; Online: Lung surgery in children and their post-operative risk of respiratory infection.

Fleming, Mark A / Xu, Thomas O / Gander, Jeffrey W / Levin, Daniel E

Pediatric surgery international

2021 Volume 37, Issue 5, Page(s) 627–630

Abstract: Purpose: Pediatric surgeons at our institution are often asked by families about a theoretical increased risk of severe common upper respiratory infections in children status post lung resection. No data exist on this topic. We, therefore, aimed to ... ...

Abstract	Purpose: Pediatric surgeons at our institution are often asked by families about a theoretical increased risk of severe common upper respiratory infections in children status post lung resection. No data exist on this topic. We, therefore, aimed to examine the risk of severe respiratory infection in children after pulmonary resection. Methods: A chart review was conducted on all pediatric patients who underwent pulmonary resection between August 1st, 2009 and January 31st, 2019. Collected data included patient characteristics, operation, complications and any admission for respiratory infection. Results: Fifty-seven patients met inclusion criteria. Resections included lobectomy (45.6%), segmentectomy (14.0%), and wedge resection (40.4%). Twelve (21.1%) were immunocompromised and 6 (10.5%) had post-operative complications. Within 1 year of surgery, 2 (3.5%) patients were hospitalized for a viral upper respiratory illness (URI), 1 (1.8%) for bacterial pneumonia, and none due to influenza. Conclusion: In the general pediatric population, the risk of admission for respiratory illness is 3-21%. At this institution, overall risk of respiratory infection after lung resection appears comparable to baseline community risk. Our findings could aid counseling pediatric patients and their families regarding the 1-year risk of infection after lung resection.
MeSH term(s)	Child ; Female ; Humans ; Infant ; Lung/surgery ; Lung Neoplasms/surgery ; Male ; Pediatrics ; Pneumonectomy ; Postoperative Complications ; Respiratory Tract Infections/etiology
Language	English
Publishing date	2021-01-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	632773-4
ISSN	1437-9813 ; 0179-0358
ISSN (online)	1437-9813
ISSN	0179-0358
DOI	10.1007/s00383-020-04851-5
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Zs.A 2138: Show issues

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Article ; Online: Long-term complications associated with the management of sinonasal malignancies: a single center experience.

Levin, Einav G / Tzelnick, Sharon / Yaacobi, Daniel / Vainer, Igor / Mizrachi, Aviram / Popovtzer, Aron / Soudry, Ethan

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

2023 Volume 43, Issue 3, Page(s) 203–211

Abstract: Objective: The aim of this study was to review the long-term complications associated with treatment of patients with sinonasal malignancies (SNMs) and risk factors for these complications.: Methods: A retrospective analysis of all patients treated ... ...

Abstract	Objective: The aim of this study was to review the long-term complications associated with treatment of patients with sinonasal malignancies (SNMs) and risk factors for these complications. Methods: A retrospective analysis of all patients treated for SNMs at a tertiary care center between 2001 and 2018. A total of 77 patients were included. The primary outcome measure was post-treatment long-term complications. Results: Overall, long-term complications were identified in 41 patients (53%), and the most common were sinonasal (22 patients, 29%) and orbital/ocular-related (18 patients, 23%). In a multivariate regression analysis, irradiation was the only significant predictor of long-term complications (p = 0.001, OR = 18.86, CI = 3.31-107.6). No association was observed between long-term complications and tumour stage, surgical modality, or radiation dose/modality. Mean radiation dose ≥ 50 Gy to the optic nerve was associated with grade ≥ 3 visual acuity impairment (100% Conclusions: Treatment of SNMs has substantial long-term complications, which are significantly associated with radiation therapy.
MeSH term(s)	Humans ; Retrospective Studies ; Neoplasm Recurrence, Local ; Paranasal Sinus Neoplasms/surgery ; Multivariate Analysis
Language	English
Publishing date	2023-05-18
Publishing country	Italy
Document type	Journal Article
ZDB-ID	604898-5
ISSN	1827-675X ; 0392-100X
ISSN (online)	1827-675X
ISSN	0392-100X
DOI	10.14639/0392-100X-N1902
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Zs.B 2608: Show issues

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Article ; Online: Food Insecurity and Obesity in US Adolescents: A Population-Based Analysis.

Fleming, Mark A / Kane, William J / Meneveau, Max O / Ballantyne, Christopher C / Levin, Daniel E

Childhood obesity (Print)

2021 Volume 17, Issue 2, Page(s) 110–115

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adolescent ; Cross-Sectional Studies ; Food Insecurity ; Food Supply ; Humans ; Male ; Pediatric Obesity/epidemiology ; Poverty
Language	English
Publishing date	2021-01-22
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2639910-6
ISSN	2153-2176 ; 2153-2168
ISSN (online)	2153-2176
ISSN	2153-2168
DOI	10.1089/chi.2020.0158
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Article: The Enteric Nervous System and Its Emerging Role as a Therapeutic Target.

Fleming, Mark A / Ehsan, Lubaina / Moore, Sean R / Levin, Daniel E

Gastroenterology research and practice

2020 Volume 2020, Page(s) 8024171

Abstract: The gastrointestinal (GI) tract is innervated by the enteric nervous system (ENS), an extensive neuronal network that traverses along its walls. Due to local reflex circuits, the ENS is capable of functioning with and without input from the central ... ...

Abstract	The gastrointestinal (GI) tract is innervated by the enteric nervous system (ENS), an extensive neuronal network that traverses along its walls. Due to local reflex circuits, the ENS is capable of functioning with and without input from the central nervous system. The functions of the ENS range from the propulsion of food to nutrient handling, blood flow regulation, and immunological defense. Records of it first being studied emerged in the early 19
Language	English
Publishing date	2020-09-08
Publishing country	Egypt
Document type	Journal Article ; Review
ZDB-ID	2435460-0
ISSN	1687-630X ; 1687-6121
ISSN (online)	1687-630X
ISSN	1687-6121
DOI	10.1155/2020/8024171
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Article: Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit

Moneme, Chioma / Kausch, Sherry L. / Belmonte, Briana M. / Fleming II, Mark A. / Levin, Daniel E. / Sullivan, Brynne A.

American Journal of Perinatology

2024

Abstract	Objective: Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics (HRCs) such as decreased variability occur due to the inflammatory response to sepsis in preterm infants. This study aimed to test the hypothesis that infants with gastroschisis have decreased heart rate variability (HRV) after birth and that this physiomarker may predict outcomes. Study Design: We analyzed heart rate data from and clinical variables for all infants admitted with gastroschisis from 2009 to 2020. Results: Forty-seven infants were admitted during the study period and had available data. Complex gastroschisis infants had reduced HRV after birth. For those with sepsis and necrotizing enterocolitis, abnormal HRCs occurred early in the course of illness. Conclusion: Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on total parenteral nutrition. Key Points: Infants with gastroschisis can be classified into two subcategories, simple and complex disease. Those with complex disease often require prolonged stays in the neonatal intensive care unit and costly hospitalizations. We hypothesized that infants with complex gastroschisis are more likely to have abnormal HRC due to intestinal inflammation. In this study, we identified associations between abnormal HRV, heart rate characteristicHRC, and the development of gastroschisis complications. Additionally, we described differences in clinical characteristics between infants with complex versus simple gastroschisis.
Keywords	abdominal defect ; congenital anomaly ; heart rate characteristics ; heart rate variability ; gastroschisis
Language	English
Publishing date	2024-01-12
Publisher	Thieme Medical Publishers, Inc.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	605671-4
ISSN	1098-8785 ; 0735-1631
ISSN (online)	1098-8785
ISSN	0735-1631
DOI	10.1055/a-2244-0148
Database	Thieme publisher's database

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Zs.A 1929: Show issues

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Article ; Online: Network residues: The enduring impact of intra-organizational dormant ties.

McCarthy, John E / Levin, Daniel Z

The Journal of applied psychology

2019 Volume 104, Issue 11, Page(s) 1434–1445

Abstract: It is often seen as axiomatic in the social capital literature that relationships require ongoing maintenance to remain valuable. As a result, nearly all social network research has only considered relationships that are active (or recently restored to ... ...

Abstract	It is often seen as axiomatic in the social capital literature that relationships require ongoing maintenance to remain valuable. As a result, nearly all social network research has only considered relationships that are active (or recently restored to activity after a period of dormancy). Seldom considered is the impact of still-dormant, unmaintained ties that remain dormant. Using two bounded-network studies (one in a school district, one in a private company), we find consistently that still-dormant ties increase employees' organizational commitment. However, we also find that active ties can "dilute" this effect, rendering dormant ties less relevant and meaningful to individuals, or act as "preservatives" keeping dormant ties relevant and valued. In a third, vignette-based study, we find two mechanisms for the effect of dormant ties on organizational commitment: perceptions of the past (fond recollections) and future (information access). Thus, we offer a more time-oriented, layered theory of social network ties that can be activated in people's minds even when not active in practice. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
MeSH term(s)	Adult ; Employment/psychology ; Humans ; Interpersonal Relations ; Personnel Loyalty ; Social Capital ; Social Networking
Language	English
Publishing date	2019-04-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	219157-x
ISSN	1939-1854 ; 0021-9010
ISSN (online)	1939-1854
ISSN	0021-9010
DOI	10.1037/apl0000410
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Article ; Online: Abscess After Appendectomy: Predisposing Factors.

Levin, Daniel E / Pegoli, Walter

Advances in surgery

2015 Volume 49, Page(s) 263–280

MeSH term(s)	Abdominal Abscess/epidemiology ; Appendectomy/adverse effects ; Appendicitis/surgery ; Causality ; Global Health ; Humans
Language	English
Publishing date	2015
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	411889-3
ISSN	1878-0555 ; 0065-3411
ISSN (online)	1878-0555
ISSN	0065-3411
DOI	10.1016/j.yasu.2015.03.010
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