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  1. Article ; Online: Prof A. K. Bajaj (1945-2021).

    Saraswat, Abir / Srivastava, Pradeep Kumar / Sharma, Rajeev

    Indian journal of dermatology, venereology and leprology

    2021  Volume 87, Issue 2, Page(s) 319–320

    MeSH term(s) Dermatologists/history ; Faculty/history ; History, 20th Century ; History, 21st Century ; Humans ; Male
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_234_2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ethical use of topical corticosteroids.

    Saraswat, Abir

    Indian journal of dermatology

    2014  Volume 59, Issue 5, Page(s) 469–472

    Abstract: Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, ... ...

    Abstract Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, beneficence and non-maleficence are all raised frequently when we prescribe topical corticosteroids to our patients. We need to be aware of situations when conflicts between these issues arise and have a clear thought process about resolving them. This can only be achieved if we have a thorough understanding of the skin disease being treated coupled with expertise in the use of the varied potencies and available dosage forms of topical corticosteroids. A good understanding of human psychology and effective communication is also needed to use these agents optimally.
    Language English
    Publishing date 2014-10-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/0019-5154.139877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comparative Efficacy and Safety of Super-Bioavailable Itraconazole-130 mg Once Daily in Obese and Non-Obese Patients of Glabrous Tinea.

    Shenoy, Manjunath / De, Abhishek / Shah, Bela / Das, Anupam / Saraswat, Abir / Lahiri, Koushik / Dhoot, Dhiraj

    Indian dermatology online journal

    2023  Volume 14, Issue 6, Page(s) 839–843

    Abstract: Background: Obesity is considered one of the risk factors for dermatophytosis and warrants systemic therapy. Itraconazole is the most commonly used antifungal, but owing to pharmacokinetic challenges, super-bioavailable itraconazole (SITZ) was approved ... ...

    Abstract Background: Obesity is considered one of the risk factors for dermatophytosis and warrants systemic therapy. Itraconazole is the most commonly used antifungal, but owing to pharmacokinetic challenges, super-bioavailable itraconazole (SITZ) was approved globally, recently. For the management of dermatophytosis in obese patients, there are mixed opinions regarding the dosing of systemic antifungals.
    Materials and methods: This study was conducted to compare the efficacy and safety of SITZ-130 mg once daily in glabrous tinea or dermatophytosis in obese and non-obese patients for a total duration of 10 weeks on 87 eligible patients. Efficacy and safety assessments were done at weeks 3 and 6 with follow-up at week 10 for relapse. The primary objective was to assess the proportion of patients achieving complete cure at week 6 with the assessment of safety, clinical, and mycological cure rates as secondary objectives.
    Results: Out of 87 patients, 80 were considered for analysis. At week 6, 22/35 (63%) and 33/45 (73%) patients in obese and non-obese groups were completely cured (
    Conclusion: SITZ-130 mg once daily achieved desired and similar clinical response in obese patients as of non-obese patients suffering from dermatophytosis, and hence, a higher dose may not require in obesity.
    Language English
    Publishing date 2023-10-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2585814-2
    ISSN 2249-5673 ; 2229-5178
    ISSN (online) 2249-5673
    ISSN 2229-5178
    DOI 10.4103/idoj.idoj_120_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ethical use of topical corticosteroids

    Abir Saraswat

    Indian Journal of Dermatology, Vol 59, Iss 5, Pp 469-

    2014  Volume 472

    Abstract: Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, ... ...

    Abstract Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, beneficence and non-maleficence are all raised frequently when we prescribe topical corticosteroids to our patients. We need to be aware of situations when conflicts between these issues arise and have a clear thought process about resolving them. This can only be achieved if we have a thorough understanding of the skin disease being treated coupled with expertise in the use of the varied potencies and available dosage forms of topical corticosteroids. A good understanding of human psychology and effective communication is also needed to use these agents optimally.
    Keywords Adverse effects ; medical ethics ; topical corticosteroids ; Medicine ; R ; Dermatology ; RL1-803
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Ethical use of topical corticosteroids

    Abir Saraswat

    Indian Journal of Dermatology, Vol 59, Iss 5, Pp 469-

    2014  Volume 472

    Abstract: Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, ... ...

    Abstract Dermatologists rely very heavily on corticosteroids for treating many common dermatoses. Concerns about their incorrect use are widely expressed both in lay public and specialist discourse. From the point of view of medical ethics, issues of autonomy, beneficence and non-maleficence are all raised frequently when we prescribe topical corticosteroids to our patients. We need to be aware of situations when conflicts between these issues arise and have a clear thought process about resolving them. This can only be achieved if we have a thorough understanding of the skin disease being treated coupled with expertise in the use of the varied potencies and available dosage forms of topical corticosteroids. A good understanding of human psychology and effective communication is also needed to use these agents optimally.
    Keywords Adverse effects ; medical ethics ; topical corticosteroids ; Medicine ; R ; Dermatology ; RL1-803
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Surrogate advertisement of a super-potent corticosteroid-containing cream: An alarming development and a cautionary tale of its consequences.

    Saraswat, Abir / Damisetty, Rajetha

    Indian journal of dermatology, venereology and leprology

    2018  Volume 85, Issue 1, Page(s) 104–106

    MeSH term(s) Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/adverse effects ; Advertising as Topic/standards ; Child, Preschool ; Counterfeit Drugs/administration & dosage ; Counterfeit Drugs/adverse effects ; Humans ; Hypopigmentation/chemically induced ; Hypopigmentation/diagnosis ; Internet/standards ; Male ; Skin Cream/administration & dosage ; Skin Cream/adverse effects
    Chemical Substances Adrenal Cortex Hormones ; Counterfeit Drugs
    Language English
    Publishing date 2018-11-28
    Publishing country India
    Document type Case Reports ; Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.4103/ijdvl.IJDVL_22_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Topical Itraconazole Formulations: Unscrupulous Pharmaceutical Companies and Lax Indian Drug Regulators Endangering a Precious Drug.

    Verma, Shyam Bhanushankar / Saraswat, Abir / Rao, P Narsimha / Dogra, Sunil

    Indian dermatology online journal

    2020  Volume 11, Issue 5, Page(s) 806–811

    Language English
    Publishing date 2020-09-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 2585814-2
    ISSN 2249-5673 ; 2229-5178
    ISSN (online) 2249-5673
    ISSN 2229-5178
    DOI 10.4103/idoj.IDOJ_659_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Sudden irreversible worsening of myopia with isotretinoin treatment.

    Saraswat, Abir

    Indian journal of dermatology, venereology and leprology

    2011  Volume 77, Issue 5, Page(s) 611–612

    MeSH term(s) Disease Progression ; Humans ; Isotretinoin/adverse effects ; Male ; Myopia/drug therapy ; Myopia/pathology ; Young Adult
    Chemical Substances Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2011-09
    Publishing country India
    Document type Case Reports ; Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.4103/0378-6323.84083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Contact allergy to topical corticosteroids and sunscreens.

    Saraswat, Abir

    Indian journal of dermatology, venereology and leprology

    2012  Volume 78, Issue 5, Page(s) 552–559

    Abstract: Topical corticosteroids and sunscreens are extensively used formulations, both as over-the-counter products and as prescription medicines. Topical corticosteroids are increasingly being recognized as causes of allergic contact dermatitis. Because of ... ...

    Abstract Topical corticosteroids and sunscreens are extensively used formulations, both as over-the-counter products and as prescription medicines. Topical corticosteroids are increasingly being recognized as causes of allergic contact dermatitis. Because of their anti-inflammatory property, contact allergy to these agents may be difficult to suspect and prove. With corticosteroid allergy, there are special issues in patch testing that need to be considered: Screening tests need to be done with budesonide and tixocortol pivalate, and delayed readings are essential to pick up all positive cases. Preventive advice needs to be tailored according to the structural and chemical peculiarities of a particular molecule. Sunscreen allergy is a significant part of cosmetic allergy; especially in cases of photoallergic reactions. Each passing decade is bringing forth new allergens in this class. In many countries, benzophenones have recently been replaced by octocrylene as the leading causes of contact dermatitis to sunscreens. This article provides a broad overview of corticosteroid and sunscreen allergy so that the readers are aware of these important emerging classes of allergens.
    MeSH term(s) Administration, Cutaneous ; Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/adverse effects ; Cross Reactions ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Allergic Contact/therapy ; Humans ; Patch Tests ; Sunscreening Agents/adverse effects
    Chemical Substances Adrenal Cortex Hormones ; Sunscreening Agents
    Language English
    Publishing date 2012-09
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.4103/0378-6323.100520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Use of Apremilast in Psoriasis: An Indian Perspective on Real-World Scenarios.

    Rajagopalan, Murlidhar / Dogra, Sunil / Saraswat, Abir / Varma, Sachin / Banodkar, Pravin

    Psoriasis (Auckland, N.Z.)

    2021  Volume 11, Page(s) 109–122

    Abstract: Apremilast, an oral phosphodiesterase-4 inhibitor, is approved for use in the management of psoriasis and psoriatic arthritis. Although its efficacy and safety have been well established in clinical studies, in real-world settings, different practice ... ...

    Abstract Apremilast, an oral phosphodiesterase-4 inhibitor, is approved for use in the management of psoriasis and psoriatic arthritis. Although its efficacy and safety have been well established in clinical studies, in real-world settings, different practice scenarios have been reported. This review paper serves to evaluate clinical real-world scenarios and aspects of treatment for which the information in the literature was considered to be lacking or controversial. Following a literature review, a panel of five dermatologists with expertise in psoriasis considered five scenarios; namely, the positioning of apremilast in psoriasis, its use in difficult-to-treat areas, special conditions and populations, safety, dose titration and dose in maintenance therapy. These were then assessed with psoriasis experts in India using a web-based questionnaire. A total of 28 questions were discussed regarding these scenarios. According to the responses, apremilast is effective in stable mild to moderate psoriasis as monotherapy and in severe psoriasis in combination. Also, a positive response was received with regard to its effectiveness in difficult locations such as the scalp, palms and soles. To reduce adverse effects, prolonged titration therapy over 4 weeks is required and lower doses can be prescribed to maintain remission. Apremilast therapy should be continued for a minimum of 8 weeks once initiated to achieve the desired results, and the total duration of therapy should be about 24 weeks for better efficacy. It is also effective in many other cases, such as obese patients, patients with hepatitis B or C and HIV, or patients on polypharmacy. It was also reported that apremilast requires less prescreening and monitoring than other conventional and biologic systemic therapies. Overall, apremilast is an attractive option for the individualized treatment of psoriasis owing to its favorable safety profile, its ease of oral administration without the need for screening or ongoing laboratory monitoring, and its positive impact on symptoms and lesions in difficult-to-treat areas.
    Language English
    Publishing date 2021-08-14
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2695573-8
    ISSN 2230-326X ; 2230-326X
    ISSN (online) 2230-326X
    ISSN 2230-326X
    DOI 10.2147/PTT.S320810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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