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  1. Article ; Online: Response to Comment on Chen et al. Ultra-Processed Food Consumption and Risk of Type 2 Diabetes: Three Large Prospective U.S. Cohort Studies. Diabetes Care 2023;46:1335-1344.

    Chen, Zhangling / Khandpur, Neha / Drouin-Chartier, Jean-Philippe

    Diabetes care

    2024  Volume 47, Issue 2, Page(s) e24–e25

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/epidemiology ; Prospective Studies ; Food, Processed ; Cohort Studies ; Risk Factors
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dci23-0088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ultra-Processed Food Consumption and Risk of Type 2 Diabetes: Three Large Prospective U.S. Cohort Studies.

    Chen, Zhangling / Khandpur, Neha / Desjardins, Clémence / Wang, Lu / Monteiro, Carlos A / Rossato, Sinara L / Fung, Teresa T / Manson, JoAnn E / Willett, Walter C / Rimm, Eric B / Hu, Frank B / Sun, Qi / Drouin-Chartier, Jean-Philippe

    Diabetes care

    2023  Volume 46, Issue 7, Page(s) 1335–1344

    Abstract: ... diabetes (T2D) risk among 3 large U.S. cohorts, conducted a meta-analysis of prospective cohort studies ... and assessed meta-evidence quality using the NutriGrade scoring system.: Results: Among the U.S ... with lower risk in the U.S. cohorts. ...

    Abstract Objective: We examined the relationship between ultra-processed food (UPF) intake and type 2 diabetes (T2D) risk among 3 large U.S. cohorts, conducted a meta-analysis of prospective cohort studies, and assessed meta-evidence quality.
    Research design and methods: We included 71,871 women from the Nurses' Health Study, 87,918 women from the Nurses' Health Study II, and 38,847 men from the Health Professional Follow-Up Study. Diet was assessed using food frequency questionnaires and UPF was categorized per the NOVA classification. Associations of total and subgroups of UPF with T2D were assessed using Cox proportional hazards models. We subsequently conducted a meta-analysis of prospective cohort studies on total UPF and T2D risk, and assessed meta-evidence quality using the NutriGrade scoring system.
    Results: Among the U.S. cohorts (5,187,678 person-years; n = 19,503 T2D cases), the hazard ratio for T2D comparing extreme quintiles of total UPF intake (percentage of grams per day) was 1.46 (95% CI 1.39-1.54). Among subgroups, refined breads; sauces, spreads, and condiments; artificially and sugar-sweetened beverages; animal-based products; and ready-to-eat mixed dishes were associated with higher T2D risk. Cereals; dark and whole-grain breads; packaged sweet and savory snacks; fruit-based products; and yogurt and dairy-based desserts were associated with lower T2D risk. In the meta-analysis (n = 415,554 participants; n = 21,932 T2D cases), each 10% increment in total UPF was associated with a 12% (95% CI 10%-13%) higher risk. Per NutriGrade, high-quality evidence supports this relationship.
    Conclusions: High-quality meta-evidence shows that total UPF consumption is associated with higher T2D risk. However, some UPF subgroups were associated with lower risk in the U.S. cohorts.
    MeSH term(s) Female ; Humans ; Cohort Studies ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/etiology ; Diet/adverse effects ; Fast Foods ; Follow-Up Studies ; Food, Processed ; Fruit ; Prospective Studies ; Male
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dc22-1993
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  3. Article ; Online: Prurigo nodularis with cornoid lamellation.

    Gupta, Sachin / Khandpur, Sujay

    Indian journal of dermatology, venereology and leprology

    2023  , Page(s) 1–2

    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_998_2022
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  4. Article ; Online: Langerhans cell histiocytosis presenting as perianal ulcers.

    Sharma, Ananya / Mondal, Avik / Aggarwal, Arnav / Khandpur, Sujay

    Indian journal of dermatology, venereology and leprology

    2024  , Page(s) 1–2

    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_204_2023
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  5. Article ; Online: Clinical dermatology through case studies.

    Khandpur, Sujay

    Indian journal of dermatology, venereology and leprology

    2019  Volume 86, Issue 1, Page(s) 104

    Language English
    Publishing date 2019-12-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.4103/ijdvl.IJDVL_826_19
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  6. Article: Drug-Induced vs. Viral Maculopapular Exanthem-Resolving the Dilemma.

    Khandpur, Sujay / Ahuja, Rhea

    Dermatopathology (Basel, Switzerland)

    2022  Volume 9, Issue 2, Page(s) 164–171

    Abstract: Maculopapular exanthem is a commonly encountered presentation in routine clinical practice, and differentiation between its two most common etiologies, i.e., viral- and drug-induced, often poses a diagnostic dilemma. Clinical, hematological and ... ...

    Abstract Maculopapular exanthem is a commonly encountered presentation in routine clinical practice, and differentiation between its two most common etiologies, i.e., viral- and drug-induced, often poses a diagnostic dilemma. Clinical, hematological and biochemical investigations are seldom reliable in distinguishing between a drug reaction and a viral exanthem. Certain key histopathological features such as the presence of a moderate degree of spongiosis, extensive basal cell damage with multiple necrotic keratinocytes and dermal infiltrate rich in eosinophils or lymphocytes and histiocytes may favor a drug exanthem, while distinctive epidermal cytopathic changes and lymphocytic vasculitis point towards a viral etiology. Similarly, notable immunohistochemical markers such as IL-5, eotaxin and FAS ligand may support a diagnosis of a drug-induced maculopapular eruption. Histopathological and immunohistochemical evaluations may help in distinguishing between the two etiologies when faced with a clinical overlap, especially in patients on multiple essential drugs when drug withdrawal and rechallenge is not feasible.
    Language English
    Publishing date 2022-05-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777118-0
    ISSN 2296-3529
    ISSN 2296-3529
    DOI 10.3390/dermatopathology9020021
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  7. Article ; Online: Lichen planus colocalising with vitiligo at photo-exposed sites: An example of locus minoris resistentiae.

    Mehta, Nikhil / Patel, Varniraj / Agarwal, Shipra / Khandpur, Sujay

    Indian journal of dermatology, venereology and leprology

    2023  , Page(s) 1–4

    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_1168_2022
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  8. Article ; Online: Papules, nodules, and periorbital edema: the many faces of self-healing juvenile cutaneous mucinosis.

    Khandpur, Sujay / Ahuja, Rhea / Choudhary, Rajat / Sharma, Ritu

    International journal of dermatology

    2023  Volume 62, Issue 12, Page(s) 1520–1522

    MeSH term(s) Humans ; Skin Diseases ; Mucinoses/diagnosis ; Skin Abnormalities ; Connective Tissue Diseases ; Edema/etiology
    Language English
    Publishing date 2023-07-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16785
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  9. Article ; Online: Traumatic dystrophic calcinosis cutis in a child successfully treated with sodium metabisulfite ointment.

    Mehta, Nikhil / Kumar Bhoi, Anil / Khandpur, Sujay

    Indian journal of dermatology, venereology and leprology

    2023  , Page(s) 1–3

    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_139_2023
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  10. Article ; Online: Effect of calcium and Vitamin D supplementation on residual ridge resorption in edentulous patients: An open-label randomized study.

    Singh, Saumyendra Vikram / Aggarwal, Himanshi / Khandpur, Mani / Trivedi, Shilpa / Pathak, Anupama / Arya, Deeksha

    Journal of Indian Prosthodontic Society

    2024  Volume 24, Issue 1, Page(s) 52–60

    Abstract: ... to oral supplementation group - S, given combined Vitamin D and calcium daily, and nonsupplementation ... RR width were - 1.84, 22.30 mm, and 4.25 mm, respectively, for the sample. In both Groups S and NS ... Groups S and NS for mean BMD, T-score, RR height and width, and RRR at both baseline and 12-month follow ...

    Abstract Aim: Complete dentures (CDs) are fabricated to rehabilitate the edentulous. Severe residual ridge resorption (RRR) compromises CD functionality, adversely affecting function, appearance, systemic health, and quality of life.
    Settings and design: The purpose of this study was to assess the benefit, if any, of calcium and Vitamin D supplementation on the rate of RRR. Retarding RRR would improve treatment prognosis and make CD fabrication less demanding.
    Materials and methods: This longitudinal, parallel, open-label randomized study was conducted in the Department of Prosthodontics of the institute. One hundred and fifty edentulous subjects underwent bone mineral density (BMD) assessment followed by CD fabrication to measure RR height and width with computerized tomographic (CT) scans. Subjects were randomized to oral supplementation group - S, given combined Vitamin D and calcium daily, and nonsupplementation group - NS. Subjects from both the groups were followed up with repeat BMD test and CT scan after 12 months. Mean BMD, RR height and width, and RRR values were collected, analyzed, and compared for the two groups using STATA 17.
    Statistical analysis used and results: Baseline mean T-score, RR height, and RR width were - 1.84, 22.30 mm, and 4.25 mm, respectively, for the sample. In both Groups S and NS, a statistically significant decrease in mandibular RR height (P = 0.000 for both) and width (P = 0.027 and 0.003, respectively) was observed at 1-year follow-up. There was a statistically insignificant difference between Groups S and NS for mean BMD, T-score, RR height and width, and RRR at both baseline and 12-month follow-up. One-year RRR rate for Group S (1.30 mm) was insignificantly lesser than for group NS (1.33 mm).
    Conclusion: Short-term oral calcium and Vitamin D supplementation was ineffective in reducing RRR and improving BMD.
    MeSH term(s) Humans ; Quality of Life ; Calcium, Dietary ; Mouth, Edentulous ; Vitamin D ; Dietary Supplements
    Chemical Substances Calcium, Dietary ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2024-01-24
    Publishing country India
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 1998-4057
    ISSN (online) 1998-4057
    DOI 10.4103/jips.jips_455_23
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