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Article ; Online: Reply to: Jerry R. John, M.Ch. Respond to "microsurgery and limb salvage after electrical burn injury".

Hsiao, Yen-Chang / Yang, Jui-Yung / Chang, Cheng-Jen / Lin, Chih-Hung / Chang, Shu-Yin / Chuang, Shiow-Shuh

Burns : journal of the International Society for Burn Injuries

2013 Volume 39, Issue 8, Page(s) 1648–1649

MeSH term(s)	Burns, Electric/surgery ; Free Tissue Flaps/blood supply ; Humans ; Male ; Reconstructive Surgical Procedures/methods ; Upper Extremity/injuries
Language	English
Publishing date	2013-12
Publishing country	Netherlands
Document type	Comment ; Letter
ZDB-ID	197308-3
ISSN	1879-1409 ; 0305-4179
ISSN (online)	1879-1409
ISSN	0305-4179
DOI	10.1016/j.burns.2013.06.018
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Zs.A 1250: Show issues

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Article ; Online: Relapsed B-cell prolymphocytic leukemia (B-PLL) with distinctive granular inclusion bodies.

Su, Mei-Yu / Chen, Tsung-Chih / Teng, Chieh-Lin Jerry / Wu, Cheng-Han

International journal of laboratory hematology

2024

Language	English
Publishing date	2024-01-29
Publishing country	England
Document type	Case Reports
ZDB-ID	2268590-X
ISSN	1751-553X ; 1751-5521 ; 0141-9854
ISSN (online)	1751-553X
ISSN	1751-5521 ; 0141-9854
DOI	10.1111/ijlh.14237
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Article ; Online: Photocatalytic CO

Sundar, Dhivya / Liu, Cheng-Hua / Anandan, Sambandam / Wu, Jerry J

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 14

Abstract: Carbon materials with elusive 0D, 1D, 2D, and 3D nanostructures and high surface area provide certain emerging applications in electrocatalytic and photocatalytic ... ...

Abstract	Carbon materials with elusive 0D, 1D, 2D, and 3D nanostructures and high surface area provide certain emerging applications in electrocatalytic and photocatalytic CO
Language	English
Publishing date	2023-07-13
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28145383
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Article ; Online: Influence of Sex Differences on Serum Lipid Profiles among Habitual Coffee Drinkers: Evidence from 23,072 Taiwan Biobank Participants.

Lu, Meng-Ying / Lai, Jerry Cheng-Yen / Chen, Shaw-Ji

Nutrients

2023 Volume 15, Issue 11

Abstract: The bioactive compounds of coffee are involved in lipid metabolism, and sex differences may play an important role. This study aimed to evaluate the influence of sex differences on serum lipid profiles among habitual coffee drinkers. We conducted a ... ...

Abstract	The bioactive compounds of coffee are involved in lipid metabolism, and sex differences may play an important role. This study aimed to evaluate the influence of sex differences on serum lipid profiles among habitual coffee drinkers. We conducted a nationwide cross-sectional study of 23,628 adults using data obtained from the Taiwan Biobank database. Adults who drank more than one cup of coffee per day and those who drank less than one cup per day were compared with non-drinkers. After adjusting for baseline demographics and lifestyle, a generalized linear model was used to estimate the change in serum lipid profiles in men and women and in postmenopausal and premenopausal women among different coffee-drinking behaviors. We found that habitual coffee consumption changed the serum lipid profiles of men and women. Further, coffee drinkers had higher serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and lower serum triglyceride levels than non-drinkers. Compared with premenopausal women, both men and postmenopausal women had increased serum total cholesterol and low-density lipoprotein cholesterol levels. Menopausal status may play an important role in modulating the effect of habitual coffee intake on dyslipidemia. Moreover, premenopausal women potentially benefit more from habitual coffee drinking than men and postmenopausal women.
MeSH term(s)	Adult ; Humans ; Male ; Female ; Taiwan ; Cross-Sectional Studies ; Sex Characteristics ; Biological Specimen Banks ; Cholesterol, HDL ; Cholesterol, LDL
Chemical Substances	Cholesterol, HDL ; Cholesterol, LDL
Language	English
Publishing date	2023-05-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15112576
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Article ; Online: Recent Advances on Electrochemical Sensors for Detection of Contaminants of Emerging Concern (CECs)

Chinchu Gibi / Cheng-Hua Liu / Sambandam Anandan / Jerry J. Wu

Molecules, Vol 28, Iss 23, p

2023 Volume 7916

Abstract: Contaminants of Emerging Concern (CECs), a new category of contaminants currently in the limelight, are a major issue of global concern. The pervasive nature of CECs and their harmful effects, such as cancer, reproductive disorders, neurotoxicity, etc., ... ...

Abstract	Contaminants of Emerging Concern (CECs), a new category of contaminants currently in the limelight, are a major issue of global concern. The pervasive nature of CECs and their harmful effects, such as cancer, reproductive disorders, neurotoxicity, etc., make the situation alarming. The perilous nature of CECs lies in the fact that even very small concentrations of CECs can cause great impacts on living beings. They also have a nature of bioaccumulation. Thus, there is a great need to have efficient sensors for the detection of CECs to ensure a safe living environment. Electrochemical sensors are an efficient platform for CEC detection as they are highly selective, sensitive, stable, reproducible, and prompt, and can detect very low concentrations of the analyte. Major classes of CECs are pharmaceuticals, illicit drugs, personal care products, endocrine disruptors, newly registered pesticides, and disinfection by-products. This review focusses on CECs, including their sources and pathways, health effects caused by them, and electrochemical sensors as reported in the literature under each category for the detection of major CECs.
Keywords	Contaminants of Emerging Concern ; electrochemical sensors ; Organic chemistry ; QD241-441
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Haploidentical and matched unrelated donor allogeneic hematopoietic stem cell transplantation offer similar survival outcomes for acute leukemia.

Wang, Yin-Che / Lai, Cheng-Lun / Chen, Tsung-Chih / Gau, Jyh-Pyng / Teng, Chieh-Lin Jerry

Cancer reports (Hoboken, N.J.)

2024 Volume 7, Issue 4, Page(s) e2060

Abstract: Background: Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) has emerged as an effective approach for acute leukemia, primarily due to the inherent difficulty in finding human leukocyte antigen-matched unrelated donors (MUD). ... ...

Abstract	Background: Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) has emerged as an effective approach for acute leukemia, primarily due to the inherent difficulty in finding human leukocyte antigen-matched unrelated donors (MUD). Nevertheless, it remains uncertain whether haplo-HSCT and MUD-HSCT can provide comparable outcomes in patients with acute leukemia. Aims: This study aimed to assess the overall survival (OS) and leukemia-free survival (LFS) outcomes between the MUD-HSCT and haplo-HSCT groups. Methods and results: This retrospective analysis encompassed adult patients with acute leukemia undergoing the initial allo-HSCT. Among these 85 patients, we stratified 33 patients into the MUD-HSCT group and 52 to the haplo-HSCT group. The primary outcomes were OS and LFS. The median OS was not reached in the haplo-HSCT group, while it reached 29.8 months in patients undergoing MUD-HSCT (p = .211). Likewise, the median LFS periods were 52.6 months in the haplo-HSCT group and 12.7 months in the MUD-HSCT group (p = .212). Importantly, neither the OS nor LFS showed substantial differences between the MUD-HSCT and haplo-HSCT groups. Furthermore, univariate analyses revealed that haplo-HSCT did not demonstrate a significantly higher risk of worse LFS (hazard ratio [HR], 0.69; 95% confidence interval [CI], 0.38-1.25; p = .216) or OS (HR, 0.67; 95% CI, 0.36-1.26; p = .214) than MUD-HSCT. Notably, a high European Group for Blood and Marrow Transplantation risk score (HR, 1.44; 95% CI, 1.10-1.87; p = .007) and non-complete remission (HR, 2.48; 95% CI, 1.17-5.23; p = .017) were significantly correlated with worse OS. Conclusion: Haplo-HSCT may serve as an alternative to MUD-HSCT for the treatment of acute leukemia, offering similar survival outcomes.
MeSH term(s)	Adult ; Humans ; Unrelated Donors ; Retrospective Studies ; Transplantation, Haploidentical/adverse effects ; Transplantation, Haploidentical/methods ; Leukemia, Myeloid, Acute/therapy ; Hematopoietic Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation/methods
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Journal Article
ISSN	2573-8348
ISSN (online)	2573-8348
DOI	10.1002/cnr2.2060
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Article ; Online: Magnetic resonance imaging appearance of breaststroker's knee.

Cheng, Karen Y / Chambers, Henry / Dwek, Jerry R

Pediatric radiology

2022 Volume 52, Issue 13, Page(s) 2645–2647

Abstract: Breaststroker's knee is an overuse syndrome resulting from similar repetitive movements in competitive swimmers that has been described in the orthopedic literature. The typical symptoms are medial knee pain with tenderness to palpation at the tibial ... ...

Abstract	Breaststroker's knee is an overuse syndrome resulting from similar repetitive movements in competitive swimmers that has been described in the orthopedic literature. The typical symptoms are medial knee pain with tenderness to palpation at the tibial collateral ligament or inferomedial patella. Despite these localizing symptoms on clinical exam, arthroscopic studies have failed to demonstrate a specific structural abnormality corresponding to this syndrome, although some have reported thickened medial synovial plica, medial-predominant synovitis or patellofemoral cartilage loss in association knee pain with breaststroke swimmers. We present a case of medial knee pain in a young breaststroke swimmer with magnetic resonance imaging (MRI) findings of marrow edema in the anterior aspect of the medial femoral condyle. To our knowledge, this is the first reported case of MRI findings in breaststroker's knee .
MeSH term(s)	Humans ; Knee Injuries/diagnostic imaging ; Knee Joint/diagnostic imaging ; Knee Joint/pathology ; Knee ; Pain ; Magnetic Resonance Imaging
Language	English
Publishing date	2022-06-08
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	124459-0
ISSN	1432-1998 ; 0301-0449
ISSN (online)	1432-1998
ISSN	0301-0449
DOI	10.1007/s00247-022-05407-6
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Zs.A 927: Show issues

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Article ; Online: Recent Advances on Electrochemical Sensors for Detection of Contaminants of Emerging Concern (CECs).

Gibi, Chinchu / Liu, Cheng-Hua / Anandan, Sambandam / Wu, Jerry J

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 23

Abstract	Contaminants of Emerging Concern (CECs), a new category of contaminants currently in the limelight, are a major issue of global concern. The pervasive nature of CECs and their harmful effects, such as cancer, reproductive disorders, neurotoxicity, etc., make the situation alarming. The perilous nature of CECs lies in the fact that even very small concentrations of CECs can cause great impacts on living beings. They also have a nature of bioaccumulation. Thus, there is a great need to have efficient sensors for the detection of CECs to ensure a safe living environment. Electrochemical sensors are an efficient platform for CEC detection as they are highly selective, sensitive, stable, reproducible, and prompt, and can detect very low concentrations of the analyte. Major classes of CECs are pharmaceuticals, illicit drugs, personal care products, endocrine disruptors, newly registered pesticides, and disinfection by-products. This review focusses on CECs, including their sources and pathways, health effects caused by them, and electrochemical sensors as reported in the literature under each category for the detection of major CECs.
MeSH term(s)	Water Pollutants, Chemical/analysis ; Pesticides/analysis ; Environmental Monitoring
Chemical Substances	Water Pollutants, Chemical ; Pesticides
Language	English
Publishing date	2023-12-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28237916
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Article: Detection of Environmentally Harmful Malathion Pesticides Using a Bimetallic Oxide of CuO Nanoparticles Dispersed over a 3D ZnO Nanoflower.

Gurusamy, Lakshmanan / Cheng, Ru-Wen / Anandan, Sambandam / Liu, Cheng-Hua / Wu, Jerry J

Materials (Basel, Switzerland)

2023 Volume 16, Issue 22

Abstract: Super-sensitive malathion detection was achieved using a nonenzymatic electrochemical sensor based on a CuO/ZnO-modified glassy carbon electrode (GCE). Due to the high affinity between the Cu element and the sulfur groups in malathion, the developed CuO- ... ...

Abstract	Super-sensitive malathion detection was achieved using a nonenzymatic electrochemical sensor based on a CuO/ZnO-modified glassy carbon electrode (GCE). Due to the high affinity between the Cu element and the sulfur groups in malathion, the developed CuO-ZnO/GCE sensor may bond malathion with ease, inhibiting the redox signal of the Cu element when malathion is present. In addition to significantly increasing the ability of electron transfer, the addition of 3D-flower-like ZnO enhances active sites of the sensor interface for the high affinity of malathion, giving the CuO-ZnO/GCE composite an exceptional level of sensitivity and selectivity. This enzyme-free CuO-ZnO/GCE malathion sensor demonstrates outstanding stability and excellent detection performance under optimal operating conditions with a wide linear range of malathion from 0 to 200 nM and a low detection limit of 1.367 nM. A promising alternative technique for organophosphorus pesticide (OP) determination is offered by the analytical performance of the proposed sensor, and this method can be quickly and sensitively applied to samples that have been contaminated with these pesticides.
Language	English
Publishing date	2023-11-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16227065
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Article: Feature-enhanced adversarial semi-supervised semantic segmentation network for pulmonary embolism annotation.

Cheng, Ting-Wei / Chua, Yi Wei / Huang, Ching-Chun / Chang, Jerry / Kuo, Chin / Cheng, Yun-Chien

Heliyon

2023 Volume 9, Issue 5, Page(s) e16060

Abstract: ... an unlabeled National Cheng Kung University Hospital (NCKUH) (IRB number: B-ER-108-380) dataset to train ...

Abstract	This study established a feature-enhanced adversarial semi-supervised semantic segmentation model to automatically annotate pulmonary embolism (PE) lesion areas in computed tomography pulmonary angiogram (CTPA) images. In the current study, all of the PE CTPA image segmentation methods were trained by supervised learning. However, when CTPA images come from different hospitals, the supervised learning models need to be retrained and the images need to be relabeled. Therefore, this study proposed a semi-supervised learning method to make the model applicable to different datasets by the addition of a small number of unlabeled images. By training the model with both labeled and unlabeled images, the accuracy of unlabeled images was improved and the labeling cost was reduced. Our proposed semi-supervised segmentation model included a segmentation network and a discriminator network. We added feature information generated from the encoder of the segmentation network to the discriminator so that it could learn the similarities between the prediction label and ground truth label. The HRNet-based architecture was modified and used as the segmentation network. This HRNet-based architecture could maintain a higher resolution for convolutional operations to improve the prediction of small PE lesion areas. We used a labeled open-source dataset and an unlabeled National Cheng Kung University Hospital (NCKUH) (IRB number: B-ER-108-380) dataset to train the semi-supervised learning model, and the resulting mean intersection over union (mIOU), dice score, and sensitivity reached 0.3510, 0.4854, and 0.4253, respectively, on the NCKUH dataset. Then we fine-tuned and tested the model with a small number of unlabeled PE CTPA images in a dataset from China Medical University Hospital (CMUH) (IRB number: CMUH110-REC3-173). Comparing the results of our semi-supervised model with those of the supervised model, the mIOU, dice score, and sensitivity improved from 0.2344, 0.3325, and 0.3151 to 0.3721, 0.5113, and 0.4967, respectively. In conclusion, our semi-supervised model can improve the accuracy on other datasets and reduce the labor cost of labeling with the use of only a small number of unlabeled images for fine-tuning.
Language	English
Publishing date	2023-05-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e16060
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