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Article ; Online: The dental profession expects high standards from its regulator.

Cross, Laura

2024 Volume 236, Issue 8, Page(s) 590–591

MeSH term(s)	Humans ; United Kingdom ; Dentistry/standards
Language	English
Publishing date	2024-04-26
Publishing country	England
Document type	Letter ; News
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/s41415-024-7384-x
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Article ; Online: Proposed revisions to the General Dental Council's Scope of practice guidance.

Cross, Laura

British dental journal

2023 Volume 235, Issue 2, Page(s) 117

Language	English
Publishing date	2023-07-28
Publishing country	England
Document type	News
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/s41415-023-6056-6
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Book ; Conference proceedings: Impact of shale gas on the fertiliser market

Hatfield, Oliver L. / Cross, Laura

paper presented to the International Fertiliser Society at a conference in Windsor, UK, on 24th May 2013

(Proceedings / International Fertiliser Society ; 730)

2013

Author's details	by Oliver L. Hatfield and Laura Cross
Series title	Proceedings / International Fertiliser Society ; 730 Proceedings / the International Fertiliser Society
Collection	Proceedings / the International Fertiliser Society
Language	English
Size	20 S. : graph. Darst., Kt.
Publishing place	Leek
Publishing country	Great Britain
Document type	Book ; Conference proceedings
HBZ-ID	HT018190657
ISBN	978-0-85310-367-7 ; 0-85310-367-4
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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Shelf mark	Loan status	Location
148/74	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: Changes in Therapy Are Not Associated With Increased Remission in Patients With Crohn's Disease of the Pouch.

Kayal, Maia / Deepak, Parakkal / Beniwal-Patel, Poonam / Raffals, Laura / Dubinsky, Marla / Chang, Shannon / Higgins, Peter D R / Jiang, Yue / Cross, Raymond K / Long, Millie D / Herfarth, Hans H / Barnes, Edward L

The American journal of gastroenterology

2024

Abstract: Introduction: There is a paucity of data on the real-world effectiveness of therapies in patients with Crohn's disease of the pouch.: Methods: This was a prospective multicenter study evaluating the primary outcome of remission at 12 months of ... ...

Abstract	Introduction: There is a paucity of data on the real-world effectiveness of therapies in patients with Crohn's disease of the pouch. Methods: This was a prospective multicenter study evaluating the primary outcome of remission at 12 months of therapy for Crohn's disease of the pouch. Results: One hundred thirty-four patients were enrolled. Among the 77 patients with symptoms at baseline, 35 (46.7%) achieved remission at 12 months. Of them, 12 (34.3%) changed therapy. There was no significant association between therapy patterns and remission status. Discussion: Approximately 50% with symptoms at enrollment achieved clinical remission at 12 months, most of whom did so without a change in therapy.
Language	English
Publishing date	2024-02-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	390122-1
ISSN	1572-0241 ; 0002-9270
ISSN (online)	1572-0241
ISSN	0002-9270
DOI	10.14309/ajg.0000000000002599
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Ui V Zs.36: Show issues

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Article ; Online: Redox Regulation of Ion Channels and Receptors in Pulmonary Hypertension.

Weise-Cross, Laura / Resta, Thomas C / Jernigan, Nikki L

Antioxidants & redox signaling

2019 Volume 31, Issue 12, Page(s) 898–915

Abstract: Significance: ...

Abstract	Significance:
MeSH term(s)	Animals ; Calcium/metabolism ; Humans ; Hypertension, Pulmonary/metabolism ; Ion Channels/metabolism ; Oxidation-Reduction ; Potassium/metabolism ; Receptors, Cytoplasmic and Nuclear/metabolism ; Vascular Resistance
Chemical Substances	Ion Channels ; Receptors, Cytoplasmic and Nuclear ; Potassium (RWP5GA015D) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2019-01-25
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	1483836-9
ISSN	1557-7716 ; 1523-0864
ISSN (online)	1557-7716
ISSN	1523-0864
DOI	10.1089/ars.2018.7699
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 5488: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
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Article ; Online: Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency.

Snodin, David J / Trejo-Martin, Alejandra / Ponting, David J / Smith, Graham F / Czich, Andreas / Cross, Kevin / Custer, Laura / Elloway, Joanne / Greene, Nigel / Kalgutkar, Amit S / Stalford, Susanne A / Tennant, Rachael E / Vock, Esther / Zalewski, Adam / Ziegler, Verena / Dobo, Krista L

Chemical research in toxicology

2024 Volume 37, Issue 2, Page(s) 181–198

Abstract: A thorough literature review was undertaken to understand how the pathways ... ...

Abstract	A thorough literature review was undertaken to understand how the pathways of
MeSH term(s)	Humans ; Animals ; Carcinogens/toxicity ; Nitrosamines/toxicity ; Nitrosamines/metabolism ; Mutagens/toxicity ; Rodentia/metabolism ; Carcinogenesis ; Carbon ; Mutagenicity Tests
Chemical Substances	Carcinogens ; Nitrosamines ; Mutagens ; Carbon (7440-44-0)
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	639353-6
ISSN	1520-5010 ; 0893-228X
ISSN (online)	1520-5010
ISSN	0893-228X
DOI	10.1021/acs.chemrestox.3c00327
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Zs.A 2320: Show issues

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Article ; Online: Targeting miR-223 enhances myeloid-derived suppressor cell suppressive activities in multiple sclerosis patients.

Cantoni, Claudia / Ghezzi, Laura / Choi, Jasmine / Cross, Anne H / Piccio, Laura

Multiple sclerosis and related disorders

2023 Volume 76, Page(s) 104839

Abstract: Background: Multiple sclerosis (MS) is an incurable autoimmune inflammatory demyelinating disease of the central nervous system. Several MS medications can modify disease course through effects on adaptive immune cells, while drugs targeting innate ... ...

Abstract	Background: Multiple sclerosis (MS) is an incurable autoimmune inflammatory demyelinating disease of the central nervous system. Several MS medications can modify disease course through effects on adaptive immune cells, while drugs targeting innate immunity are under investigation. Myeloid-derived suppressor cells (MDSCs) which arise during chronic inflammation, are defined by their T-cell immunosuppressive functions. MiR-223 modulates myeloid cell maturation and expansion, including MDSCs. Methods: MDSCs isolated from healthy controls (HC) and people with MS (pwMS) were co-cultured with CD4+ T-cells to study their immunosuppressive activities in vitro. Cytokines and chemokines concentration were evaluated by Luminex assay in the serum of HC, pwMS, and other neuroinflammatory diseases and correlated with MDSC activities. Results: MDSC suppressive functions are dysregulated in pwMS compared to HC, which was reversed by glucocorticoids (GC). GC specifically downregulated miR-223 levels in MDSCs and increased the expression of STAT3. In vitro assay showed that miR-223 inhibition enhanced MDSC suppressive activity, STAT3 dependently. By multiple linear regression analysis, we demonstrated that MDSC phosphorylated STAT3 was correlated with serum GM-CSF in HC and pwMS. Conclusions: These results suggest that miR-223 could be a therapeutic target for enhancing MDSC's suppressive activities as an alternative to GC.
MeSH term(s)	Humans ; Myeloid-Derived Suppressor Cells/metabolism ; Multiple Sclerosis/metabolism ; Cytokines/metabolism ; CD4-Positive T-Lymphocytes/metabolism ; Immunosuppressive Agents ; MicroRNAs/metabolism
Chemical Substances	Cytokines ; Immunosuppressive Agents ; MicroRNAs ; MIRN223 microRNA, human
Language	English
Publishing date	2023-06-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2645330-7
ISSN	2211-0356 ; 2211-0348
ISSN (online)	2211-0356
ISSN	2211-0348
DOI	10.1016/j.msard.2023.104839
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Exploring Gender Differences in Veterans in a Secondary Analysis of a Randomized Controlled Trial of Mindfulness for Chronic Pain.

Burgess, Diana J / Hagel Campbell, Emily M / Branson, Mariah / Calvert, Collin / Evans, Roni / Allen, Kelli D / Bangerter, Ann / Cross, Lee J S / Driscoll, Mary A / Hennessy, Sierra / Ferguson, John E / Friedman, Jessica K / Matthias, Marianne S / Meis, Laura A / Polusny, Melissa A / Taylor, Stephanie L / Taylor, Brent C

Women's health reports (New Rochelle, N.Y.)

2024 Volume 5, Issue 1, Page(s) 82–92

Abstract: Background: Although studies have documented higher rates of chronic pain among women Veterans compared to men Veterans, there remains a lack of comprehensive information about potential contributors to these disparities.: Materials and methods: This ...

Abstract	Background: Although studies have documented higher rates of chronic pain among women Veterans compared to men Veterans, there remains a lack of comprehensive information about potential contributors to these disparities. Materials and methods: This study examined gender differences in chronic pain and its contributors among 419 men and 392 women Veterans, enrolled in a mindfulness trial for chronic pain. We conducted descriptive analyses summarizing distributions of baseline measures, obtained by survey and through the electronic health record. Comparisons between genders were conducted using chi-square tests for categorical variables and Results: Compared to men, women Veterans were more likely to have chronic overlapping pain conditions and had higher levels of pain interference and intensity. Women had higher prevalence of psychiatric and sleep disorder diagnoses, greater levels of depression, anxiety, post-traumatic stress disorder, fatigue, sleep disturbance, stress and pain catastrophizing, and lower levels of pain self-efficacy and participation in social roles and activities. However, women were less likely to smoke or have a substance abuse disorder and used more nonpharmacological pain treatment modalities. Conclusion: Among Veterans seeking treatment for chronic pain, women differed from men in their type of pain, had greater pain intensity and interference, and had greater prevalence and higher levels of many known biopsychosocial contributors to pain. Results point to the need for pain treatment that addresses the comprehensive needs of women Veterans. Clinical Trial Registration Number: NCT04526158. Patient enrollment began on December 4, 2020.
Language	English
Publishing date	2024-02-12
Publishing country	United States
Document type	Journal Article
ISSN	2688-4844
ISSN (online)	2688-4844
DOI	10.1089/whr.2023.0086
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Impact of ferumoxytol vs gadolinium on 4D flow cardiovascular magnetic resonance measurements in small children with congenital heart disease.

Kollar, Sarah E / Udine, Michelle L / Mandell, Jason G / Cross, Russell R / Loke, Yue-Hin / Olivieri, Laura J

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

2022 Volume 24, Issue 1, Page(s) 58

Abstract: ... ventricular CHD, arterial vs venous flow, as well as low flows (defined as < 1.5 L/min) in 1V CHD.: Results ...

Abstract	Background: Cardiovascular magnetic resonance (CMR) allows for time-resolved three-dimensional phase-contrast (4D Flow) analysis of congenital heart disease (CHD). Higher spatial resolution in small infants requires thinner slices, which can degrade the signal. Particularly in infants, the choice of contrast agent (ferumoxytol vs. gadolinium) may influence 4D Flow CMR accuracy. Thus, we investigated the accuracy of 4D Flow CMR measurements compared to gold standard 2D flow phase contrast (PC) measurements in ferumoxytol vs. gadolinium-enhanced CMR of small CHD patients with shunt lesions. Methods: This was a retrospective study consisting of CMR studies from complex CHD patients less than 20 kg who had ferumoxytol or gadolinium-enhanced 4D Flow and standard two-dimensional phase contrast (2D-PC) flow collected. 4D Flow clinical software (Arterys) was used to measure flow in great vessels, systemic veins, and pulmonary veins. 4D Flow accuracy was defined as percent difference or correlation against conventional measurements (2D-PC) from the same vessels. Subgroup analysis was performed on two-ventricular vs single-ventricular CHD, arterial vs venous flow, as well as low flows (defined as < 1.5 L/min) in 1V CHD. Results: Twenty-one ferumoxytol-enhanced and 23 gadolinium-enhanced CMR studies were included, with no difference in age (2.1 ± 1.6 vs. 2.3 ± 1.9 years, p = 0.70), patient body surface area (0.50 ± 0.2 vs. 0.52 ± 0.2 m Conclusions: Ferumoxytol-enhanced 4D Flow CMR has improved accuracy when compared to gadolinium 4D Flow CMR, particularly for infants with small vessels in CHD.
MeSH term(s)	Child ; Infant ; Humans ; Gadolinium ; Ferrosoferric Oxide ; Retrospective Studies ; Blood Flow Velocity ; Predictive Value of Tests ; Heart Defects, Congenital/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Heart Ventricles ; Magnetic Resonance Spectroscopy ; Reproducibility of Results
Chemical Substances	Gadolinium (AU0V1LM3JT) ; Ferrosoferric Oxide (XM0M87F357)
Language	English
Publishing date	2022-11-10
Publishing country	England
Document type	Journal Article
ZDB-ID	1458034-2
ISSN	1532-429X ; 1097-6647
ISSN (online)	1532-429X
ISSN	1097-6647
DOI	10.1186/s12968-022-00886-w
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Article ; Online: Dietary Patterns Are Not Associated With Disease Activity Among Patients With Inflammatory Conditions of the Pouch in a Prospective Cohort.

Barnes, Edward L / Beniwal-Patel, Poonam / Deepak, Parakkal / Raffals, Laura / Kayal, Maia / Dubinsky, Marla / Chang, Shannon / Higgins, Peter D R / Barr, Jennifer I / Anderson, Chelsea / Cross, Raymond K / Long, Millie D / Herfarth, Hans H

Crohn's & colitis 360

2023 Volume 5, Issue 3, Page(s) otad039

Abstract: Background: Evidence-based recommendations regarding the influence of diet on inflammatory conditions of the pouch after restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) are limited.: Methods: We analyzed dietary patterns at ... ...

Abstract	Background: Evidence-based recommendations regarding the influence of diet on inflammatory conditions of the pouch after restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) are limited. Methods: We analyzed dietary patterns at enrollment in a prospective registry of patients with 1 of 4 inflammatory conditions of the pouch (acute pouchitis, chronic antibiotic-dependent pouchitis, chronic antibiotic refractory pouchitis, and Crohn's disease of the pouch). We analyzed dietary intake by disease activity at enrollment and then compared dietary patterns among patients who remained in remission throughout the 12-month follow-up to those patients who experienced a disease relapse. We also compared dietary patterns among patients with inflammatory conditions of the pouch to the United States Department of Agriculture (USDA) recommended daily goals. Results: Among 308 patients, there were no differences in dietary patterns among patients with 1 of the 4 disease states at enrollment. Additionally, among the 102 patients in remission at baseline, there were no significant differences noted among patients who went on to experience a disease flare in the 12 months after enrollment compared to those patients who remained in remission. However, patients with inflammatory conditions of the pouch demonstrated decreased intake of several food groups and macronutrients including dairy, fruits, vegetables, whole grains, and fiber when compared to USDA recommendations. Conclusions: In a prospective cohort, we demonstrated no impact of dietary patterns on disease activity. The relative deficiencies in several food groups and macronutrients among patients after IPAA indicate the potential role of targeted nutritional counseling in this population.
Language	English
Publishing date	2023-07-27
Publishing country	England
Document type	Journal Article
ISSN	2631-827X
ISSN (online)	2631-827X
DOI	10.1093/crocol/otad039
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