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Article ; Online: Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Detection of acute thoracic aortic dissection with D-dimer.

VanderLinden, Chad

Emergency medicine journal : EMJ

2008  Volume 24, Issue 12, Page(s) 846–847

Abstract: A short cut review was carried out to establish whether a raised D-dimer could be used to identify patients with an acute thoracic aortic dissection. Seven papers were found addressing the clinical question. The author, date and country of publication, ... ...

Abstract A short cut review was carried out to establish whether a raised D-dimer could be used to identify patients with an acute thoracic aortic dissection. Seven papers were found addressing the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are presented in table 1. The clinical bottom line is that a D-dimer value <500 ng/ml makes the diagnosis unlikely but there is still the possibility of a thrombosed false lumen.
MeSH term(s) Aged ; Aortic Dissection/diagnosis ; Aortic Aneurysm, Thoracic/diagnosis ; Biomarkers/blood ; Emergency Service, Hospital ; Evidence-Based Medicine ; Female ; Fibrin Fibrinogen Degradation Products/analysis ; Humans
Chemical Substances Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D
Language English
Publishing date 2008-01-02
Publishing country England
Document type Journal Article ; Review
ZDB-ID 2040124-3
ISSN 1472-0213 ; 1472-0205
ISSN (online) 1472-0213
ISSN 1472-0205
DOI 10.1136/emj.2007.054981
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