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  1. Article ; Online: Harmonizing the post-analytical phase: focus on the laboratory report.

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2024  

    Abstract: The final, post-analytical, phase of laboratory testing is increasingly recognized as a fundamental step in maximizing quality and effectiveness of laboratory information. There is a need to close the loop of the total testing cycle by improving upon the ...

    Abstract The final, post-analytical, phase of laboratory testing is increasingly recognized as a fundamental step in maximizing quality and effectiveness of laboratory information. There is a need to close the loop of the total testing cycle by improving upon the laboratory report, and its notification to users. The harmonization of the post-analytical phase is somewhat complicated, mainly because it calls for communication that involves parties speaking different languages, including laboratorians, physicians, information technology specialists, and patients. Recently, increasing interest has been expressed in integrated diagnostics, defined as convergence of imaging, pathology, and laboratory tests with advanced information technology (IT). In particular, a common laboratory, radiology and pathology diagnostic reporting system that integrates text, sentinel images and molecular diagnostic data to an integrated, coherent interpretation enhances management decisions and improves quality of care.
    Language English
    Publishing date 2024-01-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-1402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Adherence to recommendations and clinical practice guidelines: not an easy task.

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2023  Volume 61, Issue 12, Page(s) 2065–2066

    MeSH term(s) Humans ; Guideline Adherence ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-09-05
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-0920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: ChatGPT: Angel or Demond? Critical thinking is still needed.

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2023  Volume 61, Issue 7, Page(s) 1131–1132

    MeSH term(s) Humans ; Thinking ; Artificial Intelligence
    Language English
    Publishing date 2023-04-25
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-0387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Value-based laboratory medicine: the time is now.

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2023  Volume 62, Issue 4, Page(s) 579–580

    MeSH term(s) Humans ; Laboratories ; Evidence-Based Medicine ; Clinical Laboratory Techniques
    Language English
    Publishing date 2023-10-09
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-1095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: COVID-19 and Biomarkers: The Contribution of the Journal.

    Plebani, Mario

    Journal of clinical medicine

    2023  Volume 12, Issue 5

    Abstract: Three years after coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO), several features of the pathogenesis and innate immune response to SARS-CoV-2 (severe acute respiratory syndrome coronavirus disease 2) ... ...

    Abstract Three years after coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO), several features of the pathogenesis and innate immune response to SARS-CoV-2 (severe acute respiratory syndrome coronavirus disease 2) have now been clarified [...].
    Language English
    Publishing date 2023-02-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12051853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Why C-reactive protein is one of the most requested tests in clinical laboratories?

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2023  Volume 61, Issue 9, Page(s) 1540–1545

    Abstract: C-reactive protein (CRP) is an acute-phase protein which is synthesized by the liver in response to the secretion of several inflammatory cytokines including interleukin 6 (IL-6), IL-1 and tumor necrosis factor (TNF). CRP was the first acute-phase ... ...

    Abstract C-reactive protein (CRP) is an acute-phase protein which is synthesized by the liver in response to the secretion of several inflammatory cytokines including interleukin 6 (IL-6), IL-1 and tumor necrosis factor (TNF). CRP was the first acute-phase protein to be described and adopted in clinical laboratories as an exquisitely sensitive systemic marker of inflammation and tissue damage. The measurement of CRP is widely used for the diagnosis and monitoring of inflammatory conditions, including sepsis, trauma, and malignancies. In the last decades, impressive advances in analytical methods (from qualitative to high-sensitivity assays), automation and availability of results in a short time, not only translated in an increasing demand for the right management of systemic inflammatory diseases, but also in evaluating subclinical inflammatory processes underlying atherothrombotic events. CRP measurement is one of the most requested laboratory tests for both the wide range of clinical conditions in which it may assure a valuable information and some analytical advantages due to the evidence that it is a "robust biomarker". Even recently, the measurement of CRP received new interest, particularly as a biomarker of severity of Coronavirus disease 2019 (COVID-19), and it deserves further concern for improving demand appropriateness and result interpretation.
    MeSH term(s) Humans ; C-Reactive Protein/metabolism ; Laboratories, Clinical ; COVID-19/diagnosis ; Biomarkers ; Acute-Phase Proteins
    Chemical Substances C-Reactive Protein (9007-41-4) ; Biomarkers ; Acute-Phase Proteins
    Language English
    Publishing date 2023-02-06
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-0086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 and Biomarkers

    Mario Plebani

    Journal of Clinical Medicine, Vol 12, Iss 1853, p

    The Contribution of the Journal

    2023  Volume 1853

    Abstract: Three years after coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO), several features of the pathogenesis and innate immune response to SARS-CoV-2 (severe acute respiratory syndrome coronavirus disease 2) ... ...

    Abstract Three years after coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO), several features of the pathogenesis and innate immune response to SARS-CoV-2 (severe acute respiratory syndrome coronavirus disease 2) have now been clarified [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Internal quality control and external quality assurance: a great past opens the way to a bright future.

    Plebani, Mario

    Advances in laboratory medicine

    2022  Volume 3, Issue 3, Page(s) 215–220

    Language Spanish
    Publishing date 2022-08-17
    Publishing country Germany
    Document type Editorial
    ISSN 2628-491X
    ISSN (online) 2628-491X
    DOI 10.1515/almed-2022-0075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Competent Well-Trained Phlebotomists.

    Plebani, Mario

    American journal of clinical pathology

    2022  Volume 157, Issue 5, Page(s) 640–641

    MeSH term(s) Blood Specimen Collection ; Humans ; Phlebotomy
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqab193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Quality in laboratory medicine and the

    Plebani, Mario

    Clinical chemistry and laboratory medicine

    2022  Volume 61, Issue 5, Page(s) 713–720

    Abstract: Quality in laboratory medicine is defined as "an unfinished journey", as the more essential the laboratory information provided, the more assured its quality should be. In the past decades, the ... ...

    Abstract Quality in laboratory medicine is defined as "an unfinished journey", as the more essential the laboratory information provided, the more assured its quality should be. In the past decades, the Journal
    MeSH term(s) Humans ; Clinical Laboratory Techniques ; Laboratories ; Clinical Laboratory Services ; Laboratories, Clinical ; Walking
    Language English
    Publishing date 2022-08-16
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2022-0755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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