Article ; Online: Subcutan és intramuscularis heterotop kalcifikáció a nyakon 42 évvel a sugárkezelést követően.
2023 Volume 164, Issue 10, Page(s) 383–387
Abstract: Radiotherapy-induced heterotopic tissue calcification is an exceedingly rare complication in the head and neck region. We report a patient with extensive, radiotherapy-induced, combined subcutaneous and intramuscular, heterotopic calcification of the ... ...
Title translation | Subcutaneous and intramuscular heterotopic calcification of the neck 42 years after radiotherapy. |
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Abstract | Radiotherapy-induced heterotopic tissue calcification is an exceedingly rare complication in the head and neck region. We report a patient with extensive, radiotherapy-induced, combined subcutaneous and intramuscular, heterotopic calcification of the neck. An 80-year-old male presented with a 2-month history of severe dysphagia and a painful ulcer on the neck 42 years after salvage total laryngectomy following radiotherapy (total dose: 80 Gy) for a T3N0M0 glottic squamous cell carcinoma. We excluded recurrence or secondary malignancy by biopsy and performed computed tomography, which revealed subcutaneous and intramuscular calcification in the area of the skin ulcer and close to the hypopharyngeal wall, moreover, total occlusion of the common carotid and vertebral arteries bilaterally. Surgical correction involved removing the calcified lesions and closure using fasciocutaneous flap transposition. The patient has been asymptomatic for the past 48 months. Radiotherapy plays an essential role in the treatment of patients with head and neck squamous cell carcinoma. Distorted postoperative anatomy, excessive scar formation, radiotherapy-induced fibrosis as well as skin and subcutaneous tissue calcification can present as atypical findings. Orv Hetil. 2023; 164(10): 383-387. |
MeSH term(s) | Aged, 80 and over ; Humans ; Male ; Choristoma/diagnosis ; Choristoma/etiology ; Head and Neck Neoplasms/radiotherapy ; Squamous Cell Carcinoma of Head and Neck/radiotherapy ; Subcutaneous Tissue/pathology ; Subcutaneous Tissue/radiation effects ; Radiotherapy/adverse effects ; Neck Muscles/pathology ; Neck Muscles/radiation effects |
Language | Hungarian |
Publishing date | 2023-03-12 |
Publishing country | Hungary |
Document type | Case Reports ; English Abstract |
ZDB-ID | 123879-6 |
ISSN | 1788-6120 ; 0030-6002 |
ISSN (online) | 1788-6120 |
ISSN | 0030-6002 |
DOI | 10.1556/650.2023.32734 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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