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  1. Article: Traditional Chinese and Western Medicines Jointly Beat COVID-19 Pandemic.

    Qing, Guang-Chao / Zhang, Hong / Bai, Yang / Luo, Yang

    Chinese journal of integrative medicine

    2020  Volume 26, Issue 6, Page(s) 403–404

    MeSH term(s) Betacoronavirus/physiology ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Humans ; Medicine, Chinese Traditional ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Signal Transduction
    Keywords covid19
    Language English
    Publishing date 2020-05-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-020-3095-6
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  2. Article ; Online: Heat shock protein

    Wen-ying Dai / Guo-qing Yao / Xi-chuan Deng / Guang-chao Zang / Jia Liu / Guang-yuan Zhang / Yu-meng Chen / Ming-qi Lv / Ting-ting Chen

    Journal of Virus Eradication, Vol 9, Iss 1, Pp 100322- (2023)

    a double-edged sword linking innate immunity and hepatitis B virus infection

    2023  

    Abstract: Heat shock proteins (HSPs), which have a variety of functions, are one of the stress protein families. In recent years, They have been reported to play a dual role in hepatitis B virus (HBV) which as persistent infection which is associated with, ... ...

    Abstract Heat shock proteins (HSPs), which have a variety of functions, are one of the stress protein families. In recent years, They have been reported to play a dual role in hepatitis B virus (HBV) which as persistent infection which is associated with, cirrhosis and liver cancer. In this article, we have summarized the regulatory mechanisms between HSPs and viruses, especially HBV and associated diseases based on HSP biological functions of in response to viral infections. In view of their potential as broad-spectrum antiviral targets, we have also discuss current progress and challenges in drug development based on HSPs, as well as the potential applications of agents that have been evaluated clinically in HBV treatment.
    Keywords Hepatitis B virus ; HSPs ; Antiviral ; Vaccine adjuvant ; Molecular chaperones ; Microbiology ; QR1-502 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Heat shock protein: a double-edged sword linking innate immunity and hepatitis B virus infection.

    Dai, Wen-Ying / Yao, Guo-Qing / Deng, Xi-Chuan / Zang, Guang-Chao / Liu, Jia / Zhang, Guang-Yuan / Chen, Yu-Meng / Lv, Ming-Qi / Chen, Ting-Ting

    Journal of virus eradication

    2023  Volume 9, Issue 1, Page(s) 100322

    Abstract: Heat shock proteins (HSPs), which have a variety of functions, are one of the stress protein families. In recent years, They have been reported to play a dual role in hepatitis B virus (HBV) which as persistent infection which is associated with, ... ...

    Abstract Heat shock proteins (HSPs), which have a variety of functions, are one of the stress protein families. In recent years, They have been reported to play a dual role in hepatitis B virus (HBV) which as persistent infection which is associated with, cirrhosis and liver cancer. In this article, we have summarized the regulatory mechanisms between HSPs and viruses, especially HBV and associated diseases based on HSP biological functions of in response to viral infections. In view of their potential as broad-spectrum antiviral targets, we have also discuss current progress and challenges in drug development based on HSPs, as well as the potential applications of agents that have been evaluated clinically in HBV treatment.
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2868549-0
    ISSN 2055-6659 ; 2055-6640
    ISSN (online) 2055-6659
    ISSN 2055-6640
    DOI 10.1016/j.jve.2023.100322
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  4. Article: [Effects of Different Treatment Methods on the Contents of Related Growth Factors Released by Platelet Rich Plasma].

    Wang, Shu-Jun / Zhao, Guang-Chao / Luo, Kai-Yun / DU, Ying / Wang, Wei / Qi, Qing / Luan, Jian-Feng

    Zhongguo shi yan xue ye xue za zhi

    2022  Volume 30, Issue 6, Page(s) 1834–1838

    Abstract: Objective: To evaluate the effect of sonication, repeated freeze-thaw cycles, calcium salt solution and their combination on the content of related growth factors (GFs) released by platelet rich plasma (PRP).: Methods: Twenty PRPs from healthy blood ... ...

    Abstract Objective: To evaluate the effect of sonication, repeated freeze-thaw cycles, calcium salt solution and their combination on the content of related growth factors (GFs) released by platelet rich plasma (PRP).
    Methods: Twenty PRPs from healthy blood donors were divided into 9 groups, including sonication group, freeze-thaw group, calcium gluconate group, calcium chloride group, sonication + calcium gluconate group, sonication + calcium chloride group, freeze-thaw + calcium gluconate group, freeze-thaw + calcium chloride group, and sonication + freeze-thaw group. After PRP activated by above 9 methods, the content of transforming growth factor-β1 (TGF-β1), vascular endothelial growth factor (VEGF), and platelet-derived growth factor-BB (PDGF-BB) were detected by ELISA.
    Results: The platelet concentration of the samples was (966.7±202.6)×10
    Conclusion: Among the 9 activated methods of PRP, there is no difference between two calcium salt solutions. And the combination of repeated freeze-thaw cycles and sonication may be the best treatment method to promote PRP to release GFs, while calcium gluconate is the weakest way.
    MeSH term(s) Humans ; Transforming Growth Factor beta1 ; Vascular Endothelial Growth Factor A ; Calcium Gluconate ; Calcium ; Calcium Chloride ; Becaplermin ; Platelet-Rich Plasma
    Chemical Substances Transforming Growth Factor beta1 ; Vascular Endothelial Growth Factor A ; Calcium Gluconate (SQE6VB453K) ; Calcium (SY7Q814VUP) ; Calcium Chloride (M4I0D6VV5M) ; Becaplermin (1B56C968OA)
    Language Chinese
    Publishing date 2022-12-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    DOI 10.19746/j.cnki.issn.1009-2137.2022.06.032
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  6. Article ; Online: Traditional Chinese and Western Medicines Jointly Beat COVID-19 Pandemic

    Qing, Guang-chao / Zhang, Hong / Bai, Yang / Luo, Yang

    Chinese Journal of Integrative Medicine

    2020  Volume 26, Issue 6, Page(s) 403–404

    Keywords Complementary and alternative medicine ; Pharmacology (medical) ; General Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-020-3095-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Ambient Temperature and Risk of Outpatient Chronic Pharyngitis Visits: A Time-series Analysis in Xinxiang, China.

    Liang, Wen Juan / Chao, Ling / Zhao, Xiang Mei / Zhang, Rong Guang / Zhao, Rui Qing / Wu, Wei Dong / Song, Jie

    Biomedical and environmental sciences : BES

    2023  Volume 36, Issue 10, Page(s) 991–995

    MeSH term(s) Humans ; Outpatients ; Temperature ; Air Pollution/analysis ; Air Pollutants/analysis ; Pharyngitis ; China ; Particulate Matter/analysis
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2023-11-06
    Publishing country China
    Document type Letter
    ZDB-ID 645083-0
    ISSN 2214-0190 ; 0895-3988
    ISSN (online) 2214-0190
    ISSN 0895-3988
    DOI 10.3967/bes2023.126
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    Zs.A 2459: Show issues Location:
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  8. Article: Reconstruction of engineered yeast factory for high yield production of ginsenosides Rg3 and Rd.

    Lin, Yuan / Wang, Yi Na / Zhang, Guang Hui / Chen, Geng / Yang, Qing Hui / Hao, Bing / Yang, Sheng Chao

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1191102

    Abstract: ... Panax ... ...

    Abstract Panax notoginseng
    Language English
    Publishing date 2023-06-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1191102
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  9. Article ; Online: Computed tomography-guided lung biopsy: a randomized controlled trial of low-dose versus standard-dose protocol.

    Fu, Yu-Fei / Li, Guang-Chao / Xu, Qing-Song / Shi, Yi-Bing / Wang, Chen / Wang, Tao

    European radiology

    2019  Volume 30, Issue 3, Page(s) 1584–1592

    Abstract: Objectives: To assess the relative diagnostic utility of low- and standard-dose computed tomography (CT)-guided lung biopsy.: Methods: In this single-center, single-blind, prospective, randomized controlled trial, patients were enrolled between ... ...

    Abstract Objectives: To assess the relative diagnostic utility of low- and standard-dose computed tomography (CT)-guided lung biopsy.
    Methods: In this single-center, single-blind, prospective, randomized controlled trial, patients were enrolled between November 2016 and June 2017. Enrolled study participants were randomly selected to undergo either low- or standard-dose CT-guided lung biopsy. Diagnostic accuracy was the primary study endpoint, whereas technical success, radiation dose, and associated complications were secondary study endpoints.
    Results: In total, 280 patients underwent study enrollment and randomization, with 271 (low-dose group, 135; standard-dose group, 136) receiving the assigned interventions. Both groups had a 100% technical success rate for CT-guided lung biopsy, and complication rates were similar between groups (p > 0.05). The mean dose-length product (36.0 ± 14.1 mGy cm vs. 361.8 ± 108.0 mGy cm, p < 0.001) and effective dose (0.5 ± 0.2 mSv vs. 5.1 ± 1.5 mSv, p < 0.001) were significantly reduced in the low-dose group participants. Sensitivity, specificity, and overall diagnostic accuracy rates in the low-dose group were 91.8%, 100%, and 94.6%, respectively, whereas in the standard-dose group, the corresponding values were 89.6%, 100%, and 92.4%, respectively. These results indicated that diagnostic performance did not differ significantly between the 2 groups. Using univariate and multivariate analyses, we found larger lesion size (p = 0.038) and procedure-related pneumothorax (p = 0.033) to both be independent predictors of diagnostic failure.
    Conclusions: Our results demonstrate that low-dose CT-guided lung biopsy can yield comparable diagnostic accuracy to standard-dose CT guidance, while significantly reducing the radiation dose delivered to patients.
    Trial registration: ClinicalTrials.gov NCT02971176 KEY POINTS: • Low-dose CT-guided lung biopsy is a safe and simple method for diagnosis of lung lesions. • Low-dose CT-guided lung biopsy can yield comparable diagnostic accuracy to standard-dose CT guidance. • Low-dose CT-guided lung biopsy can achieve a 90% reduction in radiation exposure when compared with standard-dose CT guidance.
    MeSH term(s) Female ; Humans ; Image-Guided Biopsy/methods ; Lung/diagnostic imaging ; Lung Neoplasms/diagnosis ; Male ; Middle Aged ; Prospective Studies ; ROC Curve ; Radiation Dosage ; Radiation Exposure ; Single-Blind Method ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2019-11-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-019-06464-6
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  10. Article: Preparation of T-carbon by plasma enhanced chemical vapor deposition

    Xu, Kai / Liu, Hao / Shi, Yan-Chao / You, Jing-Yang / Ma, Xing-Yu / Cui, Hui-Juan / Yan, Qing-Bo / Chen, Guang-Chao / Su, Gang

    Carbon. 2020 Feb., v. 157

    2020  

    Abstract: A novel carbon allotrope, T-carbon, is attempted to obtain by using plasma enhanced chemical vapor deposition (PECVD) on the substrates of polycrystalline diamond and single crystalline diamond, respectively. Our measured x-ray diffraction, Raman and ... ...

    Abstract A novel carbon allotrope, T-carbon, is attempted to obtain by using plasma enhanced chemical vapor deposition (PECVD) on the substrates of polycrystalline diamond and single crystalline diamond, respectively. Our measured x-ray diffraction, Raman and infrared spectra of the new form of carbon are in good agreement with the calculated results of T-carbon, and the lattice parameter meets with the results of calculation as well as the high resolution electron microscopy of T-carbon nanowires synthesized by the pulsed laser irradiating modification of carbon multiwall nanotubes, revealing that the phase of T-carbon can be identified in our samples. The experimental preparation of T-carbon by PECVD method indicates that the massive production of T-carbon may be feasible, and extensive investigations with high-throughput experiments on this novel phase are highly expected.
    Keywords Raman spectroscopy ; X-ray diffraction ; carbon ; electron microscopy ; nanotubes ; nanowires ; vapors
    Language English
    Dates of publication 2020-02
    Size p. 270-276.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0008-6223
    DOI 10.1016/j.carbon.2019.10.032
    Database NAL-Catalogue (AGRICOLA)

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