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Article ; Online: Virchow's triad: Kussmaul, Quincke and von Recklinghausen.

Stanifer, John W

2016 Volume 24, Issue 1, Page(s) 89–100

Abstract: For most of the 19th century, Germany was the centre of the medical world. From there the most innovating research came and many of the physicians of that era are known to nearly every medical student and physician of today. Virchow, Kussmaul, Quincke, ... ...

Abstract	For most of the 19th century, Germany was the centre of the medical world. From there the most innovating research came and many of the physicians of that era are known to nearly every medical student and physician of today. Virchow, Kussmaul, Quincke, von Recklinghausen, Müller and Schönlein are familiar names in today's medicine but insofar as they are merely eponyms associated with signs, symptoms, disease and anatomy. The story of their lives, their research and their influence on each other has been little examined. This is an essay about Virchow's relationship with his mentors Müller and Schönlein and how these relationships shaped the development of Kussmaul, Quincke and von Recklinghausen as students of Virchow and their work in medicine and clinical observation after leaving Virchow's laboratory.
MeSH term(s)	Anatomy/history ; Animals ; Cells ; Eponyms ; Germany ; History, 19th Century ; History, 20th Century ; Humans ; Interprofessional Relations ; Pathology/history
Language	English
Publishing date	2016-02
Publishing country	England
Document type	Biography ; Historical Article ; Journal Article ; Portraits
ZDB-ID	1159267-9
ISSN	1758-1087 ; 0967-7720
ISSN (online)	1758-1087
ISSN	0967-7720
DOI	10.1177/0967772013520101
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Zs.A 3995: Show issues

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Article ; Online: Are County Codes More Indicative of Kidney Health Than Genetic Codes?

Stanifer, John W / Hall, Yoshio N

American journal of kidney diseases : the official journal of the National Kidney Foundation

2018 Volume 72, Issue 1, Page(s) 4–6

MeSH term(s)	Genetic Code ; Humans ; Kidney Failure, Chronic ; Life Expectancy ; United States
Language	English
Publishing date	2018-06-20
Publishing country	United States
Document type	Editorial ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	604539-x
ISSN	1523-6838 ; 0272-6386
ISSN (online)	1523-6838
ISSN	0272-6386
DOI	10.1053/j.ajkd.2018.03.010
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Zs.A 1669: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 468: Show issues

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Article ; Online: Hypertension in an Emergency Department Population in Moshi, Tanzania; A Qualitative Study of Barriers to Hypertension Control.

Galson, Sophie W / Pesambili, Msafiri / Vissoci, Joao Ricardo Nickenig / Manavalan, Preeti / Hertz, Julian T / Temu, Gloria / Staton, Catherine A / Stanifer, John W

PloS one

2023 Volume 18, Issue 1, Page(s) e0279377

Abstract: Background: Sub-Saharan Africa has a high prevalence of hypertension with a low rate of awareness, treatment adherence, and control. The emergency department (ED) may represent a unique opportunity to improve hypertension screening, awareness, and ... ...

Abstract	Background: Sub-Saharan Africa has a high prevalence of hypertension with a low rate of awareness, treatment adherence, and control. The emergency department (ED) may represent a unique opportunity to improve hypertension screening, awareness, and linkage to care. We conducted a qualitative study among hypertensive patients presenting to the ED and their healthcare providers to determine barriers to hypertension care and control. Methods: In northern Tanzania, between November and December 2017, we conducted three focus group discussions among patients with hypertension presenting to the emergency department and three in-depth interviews among emergency department physicians. In our study, hypertension was defined as a single blood pressure of ≥160/100 mm Hg or a two-time average of ≥140/90 mm Hg. Barriers to care were identified by thematic analysis applying an inductive approach within the framework method. Results: We enrolled 24 total patients into three focus groups and performed three in-depth interviews with individual providers. Thematic analysis identified two major domains: 1) patient knowledge, attitudes, and practices, and 2) structural barriers to hypertension care. Four major themes emerged within the knowledge, attitudes, and practices domain, including disease chronicity, provider communication, family support, and fear-based attitudes. Within the structural domain, several themes emerged that identified barriers that impeded hypertension follow-up care and self-management, including cost, access to care, and transportation and wait time. Conclusion: Patients and physicians identified multiple barriers and facilitators to hypertension care. These perspectives may be helpful to design emergency department-based interventions that target blood pressure control and linkage to outpatient care.
MeSH term(s)	Humans ; Tanzania/epidemiology ; Hypertension/epidemiology ; Hypertension/therapy ; Qualitative Research ; Focus Groups ; Emergency Service, Hospital
Language	English
Publishing date	2023-01-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0279377
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Article ; Online: Life-sustaining technologies in resource-limited settings.

Stanifer, John W / Sharma, Abhinav

Lancet (London, England)

2017 Volume 390, Issue 10099, Page(s) 1024

MeSH term(s)	Health Resources ; Point-of-Care Systems ; Technology
Language	English
Publishing date	2017-09-13
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	3306-6
ISSN	1474-547X ; 0023-7507 ; 0140-6736
ISSN (online)	1474-547X
ISSN	0023-7507 ; 0140-6736
DOI	10.1016/S0140-6736(17)31953-0
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Ua VI Zs.5: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 94: Show issues

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Article ; Online: The global burden of kidney disease and the sustainable development goals.

Luyckx, Valerie A / Tonelli, Marcello / Stanifer, John W

Bulletin of the World Health Organization

2018 Volume 96, Issue 6, Page(s) 414–422D

Abstract: Kidney disease has been described as the most neglected chronic disease. Reliable estimates of the global burden of kidney disease require more population-based studies, but specific risks occur across the socioeconomic spectrum from poverty to affluence, ...

Abstract	Kidney disease has been described as the most neglected chronic disease. Reliable estimates of the global burden of kidney disease require more population-based studies, but specific risks occur across the socioeconomic spectrum from poverty to affluence, from malnutrition to obesity, in agrarian to post-industrial settings, and along the life course from newborns to older people. A range of communicable and noncommunicable diseases result in renal complications and many people who have kidney disease lack access to care. The causes, consequences and costs of kidney diseases have implications for public health policy in all countries. The risks of kidney disease are also influenced by ethnicity, gender, location and lifestyle. Increasing economic and health disparities, migration, demographic transition, unsafe working conditions and environmental threats, natural disasters and pollution may thwart attempts to reduce the morbidity and mortality from kidney disease. A multisectoral approach is needed to tackle the global burden of kidney disease. The sustainable development goals (SDGs) emphasize the importance of a multisectoral approach to health. We map the actions towards achieving all of the SDGs that have the potential to improve understanding, measurement, prevention and treatment of kidney disease in all age groups. These actions can also foster treatment innovations and reduce the burden of such disease in future generations.
MeSH term(s)	Conservation of Natural Resources ; Female ; Global Health ; Goals ; Humans ; Infant, Newborn ; Kidney Diseases/epidemiology ; Male ; Morbidity ; Mortality
Language	English
Publishing date	2018-04-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	80213-x
ISSN	1564-0604 ; 0042-9686 ; 0366-4996 ; 0510-8659
ISSN (online)	1564-0604
ISSN	0042-9686 ; 0366-4996 ; 0510-8659
DOI	10.2471/BLT.17.206441
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Zs.A 215: Show issues

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Article: Chronic kidney disease care models in low- and middle-income countries: a systematic review.

Stanifer, John W / Von Isenburg, Megan / Chertow, Glenn M / Anand, Shuchi

BMJ global health

2018 Volume 3, Issue 2, Page(s) e000728

Abstract: Introduction: The number of persons with chronic kidney disease (CKD) living in low- and middle-income countries (LMIC) is increasing rapidly; yet systems built to care for them have received little attention. In order to inform the development of ... ...

Abstract	Introduction: The number of persons with chronic kidney disease (CKD) living in low- and middle-income countries (LMIC) is increasing rapidly; yet systems built to care for them have received little attention. In order to inform the development of scalable CKD care models, we conducted a systematic review to characterise existing CKD care models in LMICs. Methods: We searched PubMed, Embase and WHO Global Health Library databases for published reports of CKD care models from LMICs between January 2000 and 31 October 2017. We used a combination of database-specific medical subject headings and keywords for care models, CKD and LMICs as defined by the World Bank. Results: Of 3367 retrieved articles, we reviewed the full text of 104 and identified 17 articles describing 16 programmes from 10 countries for inclusion. National efforts (n=4) focused on the prevention of end-stage renal disease through enhanced screening, public awareness campaigns and education for primary care providers. Of the 12 clinical care models, nine focused on persons with CKD and the remaining on persons at risk for CKD; a majority in the first category implemented a multidisciplinary clinic with allied health professionals or primary care providers (rather than nephrologists) in lead roles. Four clinical care models used a randomised control design allowing for assessment of programme effectiveness, but only one was assessed as having low risk for bias; all four showed significant attenuation of kidney function decline in the intervention arms. Conclusions: Overall, very few rigorous CKD care models have been reported from LMICs. While preliminary data indicate that national efforts or clinical CKD care models bolstering primary care are successful in slowing kidney function decline, limited data on regional causes of CKD to inform national campaigns, and on effectiveness and affordability of local programmes represent important challenges to scalability.
Language	English
Publishing date	2018-04-01
Publishing country	England
Document type	Journal Article
ISSN	2059-7908
ISSN	2059-7908
DOI	10.1136/bmjgh-2018-000728
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Article: Clinical nephrology research in low-resource settings: opportunities, priorities, and challenges for young investigators.

Anand, Shuchi / Stanifer, John W / Thomas, Bernadette

Clinical nephrology

2016 Volume 86 2016, Issue 13, Page(s) 8–13

Abstract: The increased recognition of the growing, worldwide burden of kidney disease has led to calls for prioritizing nephrology research in a global context. However, many challenges exist for young investigators interested in studying kidney disease in low- ... ...

Abstract	The increased recognition of the growing, worldwide burden of kidney disease has led to calls for prioritizing nephrology research in a global context. However, many challenges exist for young investigators interested in studying kidney disease in low-resource global settings. A lack of clear research priorities, limited funding options, poor infrastructure, difficulty forming partnerships, and unestablished paths for career advancement are a few examples. To discuss these issues, we held a moderated panel discussion in March 2015 as part of the 10<sup>th</sup> Conference on Kidney Disease in Disadvantaged Populations in Cape Town, South Africa. A group of senior investigators discussed research priorities for studying kidney disease in a global context, collaborations for clinical research, and strategies for dealing with the unique challenges faced by young investigators working in this field.
MeSH term(s)	Cooperative Behavior ; Developing Countries ; Humans ; Kidney Diseases/diagnosis ; Kidney Diseases/epidemiology ; Kidney Diseases/therapy ; Nephrology/organization & administration ; Research/organization & administration ; South Africa
Language	English
Publishing date	2016
Publishing country	Germany
Document type	Journal Article
ZDB-ID	185101-9
ISSN	0301-0430
ISSN	0301-0430
DOI	10.5414/CNP86S110
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Zs.A 873: Show issues

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Article ; Online: Spirituality, Coping, and Resilience Among Rural Residents Living with Chronic Kidney Disease.

Pham, Tony V / Beasley, Cherry M / Gagliardi, Jane P / Koenig, Harold G / Stanifer, John W

Journal of religion and health

2019 Volume 59, Issue 6, Page(s) 2951–2968

Abstract: Spirituality, an established resource within rural America, serves as an important coping mechanism for crises of chronic illness. We examined the effects of spirituality on chronic kidney disease (CKD) maintenance in the rural community of Robeson ... ...

Abstract	Spirituality, an established resource within rural America, serves as an important coping mechanism for crises of chronic illness. We examined the effects of spirituality on chronic kidney disease (CKD) maintenance in the rural community of Robeson County, North Carolina. We conducted nine focus group discussions and 16 interviews involving 80 diverse key informants impacted by CKD. As disenfranchised patients, they locally engaged in spirituality which mobilized personal and social resources and elicited support from a transcendent authority. Our participants developed a heuristic and aesthetic understanding of disease, built resilience and self-care skills, and improved overall coping and survival.
MeSH term(s)	Adaptation, Psychological ; Aged ; Chronic Disease ; Female ; Focus Groups ; Humans ; Interviews as Topic ; Male ; Mental Health ; Middle Aged ; North Carolina ; Qualitative Research ; Quality of Life ; Renal Dialysis ; Renal Insufficiency, Chronic/psychology ; Renal Insufficiency, Chronic/therapy ; Resilience, Psychological ; Rural Health ; Rural Population/statistics & numerical data ; Spirituality
Language	English
Publishing date	2019-08-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2017250-3
ISSN	1573-6571 ; 0022-4197
ISSN (online)	1573-6571
ISSN	0022-4197
DOI	10.1007/s10943-019-00892-w
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Article ; Online: The Importance of Global Health Experiences During Clinical Training.

Sharma, Abhinav / Khan, James S / Stanifer, John W / Seth, Puneet

Journal of the American College of Cardiology

2016 Volume 67, Issue 21, Page(s) 2558

MeSH term(s)	Curriculum ; Global Health ; International Educational Exchange
Language	English
Publishing date	2016--31
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2016.02.076
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Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

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Article ; Online: Practices and Perspectives of Traditional Bone Setters in Northern Tanzania.

Card, Elizabeth B / Obayemi, Joy E / Shirima, Octavian / Lazaro, Matayo / Massawe, Honest / Stanifer, John W / Premkumar, Ajay / Sheth, Neil P

Annals of global health

2020 Volume 86, Issue 1, Page(s) 61

Abstract: Background: Traditional health practitioners remain a critical source of care in Tanzania, more than 50% of Tanzanians frequently using their services. With a severe shortage of orthopaedic surgeons (1:3.3 million Tanzanians) traditional bone setters ( ... ...

Abstract	Background: Traditional health practitioners remain a critical source of care in Tanzania, more than 50% of Tanzanians frequently using their services. With a severe shortage of orthopaedic surgeons (1:3.3 million Tanzanians) traditional bone setters (TBSs) could potentially expand access to musculoskeletal care and improve outcomes for morbidity as a result of trauma. Objective: We sought to identify the advantages and disadvantages of traditional bone setting in Tanzania and to assess potential for collaboration between TBSs and allopathic orthopaedic surgeons. Methods: Between June and July 2017 we interviewed six TBSs identified as key informants in the regions of Kilimanjaro, Arusha, and Manyara. We conducted semi-structured interviews about practices and perspectives on allopathic healthcare, and analyzed the data using a deductive framework method. Findings: The TBSs reported that their patients were primarily recruited from their local communities via word-of-mouth communication networks. Payment methods for services included bundling costs, livestock barter, and sliding scale pricing. Potentially unsafe practices included lack of radiographic imaging to confirm reduction; cutting and puncturing of skin with unsterile tools; and rebreaking healed fractures. The TBSs described past experience collaborating with allopathic healthcare providers, referring patients to hospitals, and utilizing allopathic techniques in their practice. All expressed enthusiasm in future collaboration with allopathic hospitals. Conclusions: TBSs confer the advantages of word-of-mouth communication networks and greater financial and geographic accessibility. However, some of their practices raise concerns relating to infection, fracture malunion or nonunion, and iatrogenic trauma from manipulating previously healed fractures. A formal collaboration between TBSs and orthopaedic surgeons, based on respect and regular communication, could alleviate concerns through the development of care protocols and increase access to optimal orthopaedic care through a standardized triage and follow-up system.
MeSH term(s)	Aged ; Attitude of Health Personnel ; Fracture Fixation/methods ; Fracture Healing ; Fractures, Bone/therapy ; Fractures, Malunited/therapy ; Fractures, Ununited ; Health Workforce ; Humans ; Iatrogenic Disease ; Infection Control ; Joint Dislocations/therapy ; Male ; Medicine, African Traditional/methods ; Middle Aged ; Orthopedic Surgeons/supply & distribution ; Pain, Procedural/therapy ; Tanzania
Language	English
Publishing date	2020-06-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2821756-1
ISSN	2214-9996 ; 2214-9996
ISSN (online)	2214-9996
ISSN	2214-9996
DOI	10.5334/aogh.2878
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