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  1. Article ; Online: Reply to Francesco Montorsi, Giorgio Gandaglia, and Alberto Briganti's Letter to the Editor re: Andrew J. Vickers. Effects of Magnetic Resonance Imaging Targeting on Overdiagnosis and Overtreatment of Prostate Cancer. Eur Urol 2021;80:567-72.

    Vickers, Andrew J

    European urology

    2021  Volume 80, Issue 6, Page(s) e149

    MeSH term(s) Humans ; Magnetic Resonance Imaging ; Male ; Overdiagnosis ; Overtreatment ; Prostatectomy ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/therapy
    Language English
    Publishing date 2021-09-30
    Publishing country Switzerland
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.09.020
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  2. Article ; Online: Reply to Benjamin Davies, Keith Kowalczyk RE: Zachary Klaassen, Emily Vertosick, Andrew J. Vickers, et al. Optimal Dissemination of Scientific Manuscripts via Social Media: A Prospective Trial Comparing Visual Abstracts Versus Key Figures in Consecutive Original Manuscripts. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.01.041.

    Klaassen, Zachary / Catto, James W F / Vickers, Andrew J / Cooperberg, Matthew R / Kutikov, Alexander

    European urology

    2022  Volume 82, Issue 1, Page(s) e12

    Language English
    Publishing date 2022-04-12
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2022.04.001
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  3. Article ; Online: Eight Misconceptions about Prostate-Specific Antigen.

    Vickers, Andrew J / Lilja, Hans

    Clinical chemistry

    2024  Volume 70, Issue 1, Page(s) 13–16

    MeSH term(s) Male ; Humans ; Prostate-Specific Antigen
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1093/clinchem/hvad138
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  4. Article ; Online: Inaccurate description of staged consent.

    Vickers, Andrew J

    European journal of internal medicine

    2022  Volume 108, Page(s) 99

    Language English
    Publishing date 2022-11-18
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2022.11.019
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  5. Article ; Online: Corrigendum to "Effects of Magnetic Resonance Imaging Targeting on Overdiagnosis and Overtreatment of Prostate Cancer" [Eur Urol 2021;80:567-72].

    Vickers, Andrew J

    European urology

    2022  Volume 82, Issue 3, Page(s) e89

    Language English
    Publishing date 2022-06-14
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2022.05.022
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  6. Article ; Online: Reply to Ilias Giannakodimos' Letter to the Editor re: Jim C. Hu, Melissa Assel, Mohamad E. Allaf, et al. Transperineal Versus Transrectal Magnetic Resonance Imaging-targeted and Systematic Prostate Biopsy to Prevent Infectious Complications: The PREVENT Randomized Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.12.015.

    Hu, Jim C / Schaeffer, Edward M / Vickers, Andrew J

    European urology

    2024  

    Language English
    Publishing date 2024-04-25
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2024.04.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Letter: Adding a Coefficient for Race to the 4Kscore Improves Calibration for Black Men.

    Vickers, Andrew J / Hougen, Helen Y / Punnen, Sanoj

    The Journal of urology

    2024  Volume 211, Issue 5, Page(s) 713

    MeSH term(s) Male ; Humans ; Calibration ; Kallikreins ; Prostate-Specific Antigen
    Chemical Substances Kallikreins (EC 3.4.21.-) ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Letter
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003925
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  8. Article ; Online: Reply to Peter Ka-Fung Chiu, Xiaobo Wu, Giorgio Gandaglia, European Association of Urology Young Academic Urologists Prostate Cancer Working Party. Beyond Statistical Significance: Unveiling the Advantages of Transperineal Versus Transrectal Prostate Biopsies. Eur Urol. In press.

    Hu, Jim C / Vickers, Andrew J / Schaeffer, Edward M

    European urology

    2024  

    Language English
    Publishing date 2024-04-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2024.04.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of Magnetic Resonance Imaging Targeting on Overdiagnosis and Overtreatment of Prostate Cancer.

    Vickers, Andrew J

    European urology

    2021  Volume 80, Issue 5, Page(s) 567–572

    Abstract: Background: It has been suggested that targeting prostate lesions identified on magnetic resonance imaging (MRI) will improve the sensitivity of prostate biopsy for high-grade disease. The clinical significance of high-grade tumors found on MRI but ... ...

    Abstract Background: It has been suggested that targeting prostate lesions identified on magnetic resonance imaging (MRI) will improve the sensitivity of prostate biopsy for high-grade disease. The clinical significance of high-grade tumors found on MRI but missed on systematic biopsy is open to question.
    Objective: To determine the risk of mortality for high-grade cancers identified by MRI targeting in men who had benign systematic biopsy findings.
    Design, setting, and participants: We used data from 999 men with negative systematic biopsy and concurrent MRI-targeted biopsy in the National Cancer Institute MRI study. The comparison group consisted of 3056 men followed for 11 yr after negative sextant biopsy in the European Randomized Trial of Screening for Prostate Cancer (ERSPC).
    Outcome measurements and statistical analysis: We calculated the number of patients needed to be diagnosed (NND) and treated (NNT) following targeted biopsy in order to prevent one prostate cancer death at 11 yr. We used a simple modeling approach that involved several assumptions, such as the proportion of the deaths in ERSPC preventable by earlier detection with MRI-guided biopsy. We then varied these assumptions to assess the effects on the results.
    Results and limitations: NND and NNT were 89 and 57 for the scenario involving assumptions favorable to MRI, and 169 and 127 for a more neutral set of assumptions, respectively. Results were only more encouraging for MRI targeting under unlikely scenarios, such as 100% sensitivity for MRI and a cure rate of 100% for treatment.
    Conclusions: Although MRI may be of benefit overall, considering the decrease in overdiagnosis among men with negative MRI findings, targeting biopsy needles to MRI-detected lesions results in a large number of men diagnosed and treated per death prevented. Consideration should be given to changing guidelines on grading of MRI cores and those regarding treatment of MRI-detected high-grade prostate cancer.
    Patient summary: We carried out a modeling study to assess how magnetic resonance imaging (MRI) scan results used to target prostate cancer lesions during biopsy can affect outcomes. The model results show that if MRI-visible tumors are targeted during prostate biopsy, a large number of men need to be diagnosed and treated for prostate cancer in order to avoid just one prostate cancer death.
    MeSH term(s) Humans ; Image-Guided Biopsy/methods ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging, Interventional ; Male ; Neoplasm Grading ; Overdiagnosis ; Overtreatment ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/mortality
    Language English
    Publishing date 2021-07-20
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.06.026
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  10. Article ; Online: Reply to Geoffrey H. Rosen, Nicholas H. Chakiryan, and Katie S. Murray's Letter to the Editor re: Jim C. Hu, Melissa Assel, Mohamad E. Allaf, et al. Transperineal Versus Transrectal Magnetic Resonance Imaging-targeted and Systematic Prostate Biopsy to Prevent Infectious Complications: The PREVENT Randomized Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.12.015.

    Hu, Jim C / Vickers, Andrew J / Schaeffer, Edward M

    European urology

    2024  

    Language English
    Publishing date 2024-04-26
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2024.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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