LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 63

Search options

  1. Article ; Online: Challenges and opportunities for medical referrals at a mobile community health clinic serving sexual and gender minorities in rural South Carolina: a qualitative approach.

    Joudeh, Layla / Heavner, Smith F / Johnstone, Ethan / Propst, Shantara K / Harris, Orlando O

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 168

    Abstract: ... speaking individuals who provided care or received care from the mobile health clinic in South Carolina ...

    Abstract Background: Sexual and gender minorities (SGM) in the Southern United States face challenges in accessing sexual and gender affirming health care. Alternative care models, like inclusive mobile clinics, help mitigate barriers to care for SGM. There is limited data in the literature on the experience of medical referral processes for SGM individuals accessing services from mobile health clinics.
    Aims and objectives: The purpose of this study is to describe the medical referral experiences of SGM clients and their providers at a mobile health clinic in the Southern United States.
    Methods: We recruited English-speaking individuals who provided care or received care from the mobile health clinic in South Carolina between June 2019 and August 2020. Participants completed a brief demographic survey and a virtual in-depth, semi-structured individual interview. Data analysis was conducted using an iterative process to generate codes, categories, and themes. Data collection and analysis were terminated once thematic saturation was achieved.
    Results: The findings from this study indicated that the mobile health clinic had an inconsistent referral process that was largely dependent on providers' knowledge. Furthermore, clients and providers expressed individual barriers to the referral process, such as financial barriers, and opportunities to improve the referral process, such as an opt-in follow-up from the mobile clinic and increased mobile clinic resources.
    Conclusion: The findings in this study underscore the importance of having mobile clinics create a structured referral process that all medical providers are familiar with, and the value of hiring patient navigators that can support and refer clients to care that goes beyond the mobile health clinic setting.
    MeSH term(s) Humans ; Mobile Health Units ; South Carolina ; Public Health ; Gender Identity ; Sexual and Gender Minorities ; Referral and Consultation
    Language English
    Publishing date 2023-02-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-09141-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Antigen Presentation and Autophagy in Teleost Adaptive Immunity.

    Johnstone, Carolina / Chaves-Pozo, Elena

    International journal of molecular sciences

    2022  Volume 23, Issue 9

    Abstract: Infectious diseases are a burden for aquaculture. Antigen processing and presentation (APP) to the immune effector cells that fight pathogens is key in the adaptive immune response. At the core of the adaptive immunity that appeared in lower vertebrates ... ...

    Abstract Infectious diseases are a burden for aquaculture. Antigen processing and presentation (APP) to the immune effector cells that fight pathogens is key in the adaptive immune response. At the core of the adaptive immunity that appeared in lower vertebrates during evolution are the variable genes encoding the major histocompatibility complex (MHC). MHC class I molecules mainly present peptides processed in the cytosol by the proteasome and transported to the cell surface of all cells through secretory compartments. Professional antigen-presenting cells (pAPC) also express MHC class II molecules, which normally present peptides processed from exogenous antigens through lysosomal pathways. Autophagy is an intracellular self-degradation process that is conserved in all eukaryotes and is induced by starvation to contribute to cellular homeostasis. Self-digestion during autophagy mainly occurs by the fusion of autophagosomes, which engulf portions of cytosol and fuse with lysosomes (macroautophagy) or assisted by chaperones (chaperone-mediated autophagy, CMA) that deliver proteins to lysosomes. Thus, during self-degradation, antigens can be processed to be presented by the MHC to immune effector cells, thus, linking autophagy to APP. This review is focused on the essential components of the APP that are conserved in teleost fish and the increasing evidence related to the modulation of APP and autophagy during pathogen infection.
    MeSH term(s) Adaptive Immunity ; Animals ; Antigen Presentation ; Antigens/metabolism ; Autophagy/genetics ; Histocompatibility Antigens/metabolism ; Histocompatibility Antigens Class II/metabolism ; Lysosomes/metabolism ; Peptides/metabolism
    Chemical Substances Antigens ; Histocompatibility Antigens ; Histocompatibility Antigens Class II ; Peptides
    Language English
    Publishing date 2022-04-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23094899
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Antigen Presentation and Autophagy in Teleost Adaptive Immunity

    Carolina Johnstone / Elena Chaves-Pozo

    International Journal of Molecular Sciences, Vol 23, Iss 4899, p

    2022  Volume 4899

    Abstract: Infectious diseases are a burden for aquaculture. Antigen processing and presentation (APP) to the immune effector cells that fight pathogens is key in the adaptive immune response. At the core of the adaptive immunity that appeared in lower vertebrates ... ...

    Abstract Infectious diseases are a burden for aquaculture. Antigen processing and presentation (APP) to the immune effector cells that fight pathogens is key in the adaptive immune response. At the core of the adaptive immunity that appeared in lower vertebrates during evolution are the variable genes encoding the major histocompatibility complex (MHC). MHC class I molecules mainly present peptides processed in the cytosol by the proteasome and transported to the cell surface of all cells through secretory compartments. Professional antigen-presenting cells (pAPC) also express MHC class II molecules, which normally present peptides processed from exogenous antigens through lysosomal pathways. Autophagy is an intracellular self-degradation process that is conserved in all eukaryotes and is induced by starvation to contribute to cellular homeostasis. Self-digestion during autophagy mainly occurs by the fusion of autophagosomes, which engulf portions of cytosol and fuse with lysosomes (macroautophagy) or assisted by chaperones (chaperone-mediated autophagy, CMA) that deliver proteins to lysosomes. Thus, during self-degradation, antigens can be processed to be presented by the MHC to immune effector cells, thus, linking autophagy to APP. This review is focused on the essential components of the APP that are conserved in teleost fish and the increasing evidence related to the modulation of APP and autophagy during pathogen infection.
    Keywords antigen processing ; antigen-presenting cell ; bacteria ; chaperone-mediated autophagy ; LC3-Associated phagocytosis ; macroautophagy ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 570
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: Placing the COVID-19 Pandemic in a Marine Ecological Context

    Carolina Johnstone / José Carlos Báez

    Frontiers in Marine Science, Vol

    Potential Risks for Conservation of Marine Air-Breathing Animals and Future Zoonotic Outbreaks

    2021  Volume 8

    Keywords cetacean ; marine mammal ; reservoirs ; SARS-CoV-2 ; seabirds ; seaturtles ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Evidence of Atlantic bluefin tuna spawning in the Bay of Biscay, north-eastern Atlantic.

    Rodriguez, Jose M / Johnstone, Carolina / Lozano-Peral, Diego

    Journal of fish biology

    2021  Volume 99, Issue 3, Page(s) 964–969

    Abstract: The spawning grounds of the Atlantic bluefin tuna (Thunnus thynnus) are traditionally considered to be the Gulf of Mexico (Gulf of Mexico) and the Mediterranean Sea (Mediterranean Sea). However, for the western Atlantic, unequivocal evidence of bluefin ... ...

    Abstract The spawning grounds of the Atlantic bluefin tuna (Thunnus thynnus) are traditionally considered to be the Gulf of Mexico (Gulf of Mexico) and the Mediterranean Sea (Mediterranean Sea). However, for the western Atlantic, unequivocal evidence of bluefin spawning outside the Gulf of Mexico has been shown. In this study we present the first records of genetically confirmed bluefin larvae in the southern Bay of Biscay (eastern Atlantic). These findings provide evidence of bluefin spawning activity outside the Mediterranean Sea, in the north-eastern Atlantic. However, our results suggest that the bluefin spawning in the Bay of Biscay is a sporadic phenomenon.
    MeSH term(s) Animals ; Bays ; Gulf of Mexico ; Mediterranean Sea ; Tuna
    Language English
    Publishing date 2021-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 410564-3
    ISSN 1095-8649 ; 0022-1112
    ISSN (online) 1095-8649
    ISSN 0022-1112
    DOI 10.1111/jfb.14782
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Reservoirs of Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) in Squid and Shrimp Species of Northern Alboran Sea

    Johnstone, Carolina / Pérez, Montse / Arizcun, Marta / García-Ruiz, Cristina / Chaves-Pozo, Elena

    Viruses. 2022 Feb. 06, v. 14, no. 2

    2022  

    Abstract: The production of the aquaculture industry has increased to be equal to that of the world fisheries in recent years. However, aquaculture production faces threats such as infectious diseases. Betanodaviruses induce a neurological disease that affects ... ...

    Abstract The production of the aquaculture industry has increased to be equal to that of the world fisheries in recent years. However, aquaculture production faces threats such as infectious diseases. Betanodaviruses induce a neurological disease that affects fish species worldwide and is caused by nervous necrosis virus (NNV). NNV has a nude capsid protecting a bipartite RNA genome that consists of molecules RNA1 and RNA2. Four NNV strains distributed worldwide are discriminated according to sequence homology of the capsid protein encoded by RNA2. Since its first description over 30 years ago, the virus has expanded and reassortant strains have appeared. Preventive treatments prioritize the RGNNV (red-spotted grouper nervous necrosis virus) strain that has the highest optimum temperature for replication and the broadest range of susceptible species. There is strong concern about the spreading of NNV in the mariculture industry through contaminated diet. To surveil natural reservoirs of NNV in the western Mediterranean Sea, we collected invertebrate species in 2015 in the Alboran Sea. We report the detection of the RGNNV strain in two species of cephalopod mollusks (Alloteuthis media and Abralia veranyi), and in one decapod crustacean (Plesionika heterocarpus). According to RNA2 sequences obtained from invertebrate species and reported to date in the Mediterranean Sea, the strain RGNNV is predominant in this semienclosed sea. Neither an ecosystem- nor host-driven distribution of RGNNV were observed in the Mediterranean basin.
    Keywords Cephalopoda ; Heterocarpus ; RNA ; Redspotted grouper nervous necrosis virus ; capsid ; coat proteins ; diet ; fish ; genome ; mariculture ; nervous system diseases ; sequence homology ; squid ; temperature ; viruses ; Mediterranean Sea ; Mediterranean region
    Language English
    Dates of publication 2022-0206
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14020328
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article ; Online: Reservoirs of Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) in Squid and Shrimp Species of Northern Alboran Sea.

    Johnstone, Carolina / Pérez, Montse / Arizcun, Marta / García-Ruiz, Cristina / Chaves-Pozo, Elena

    Viruses

    2022  Volume 14, Issue 2

    Abstract: The production of the aquaculture industry has increased to be equal to that of the world fisheries in recent years. However, aquaculture production faces threats such as infectious diseases. Betanodaviruses induce a neurological disease that affects ... ...

    Abstract The production of the aquaculture industry has increased to be equal to that of the world fisheries in recent years. However, aquaculture production faces threats such as infectious diseases. Betanodaviruses induce a neurological disease that affects fish species worldwide and is caused by nervous necrosis virus (NNV). NNV has a nude capsid protecting a bipartite RNA genome that consists of molecules RNA1 and RNA2. Four NNV strains distributed worldwide are discriminated according to sequence homology of the capsid protein encoded by RNA2. Since its first description over 30 years ago, the virus has expanded and reassortant strains have appeared. Preventive treatments prioritize the RGNNV (red-spotted grouper nervous necrosis virus) strain that has the highest optimum temperature for replication and the broadest range of susceptible species. There is strong concern about the spreading of NNV in the mariculture industry through contaminated diet. To surveil natural reservoirs of NNV in the western Mediterranean Sea, we collected invertebrate species in 2015 in the Alboran Sea. We report the detection of the RGNNV strain in two species of cephalopod mollusks (
    MeSH term(s) Animals ; Decapodiformes/virology ; Disease Reservoirs/veterinary ; Disease Reservoirs/virology ; Fishes/classification ; Fishes/virology ; Genome, Viral/genetics ; Mediterranean Sea ; Nodaviridae/classification ; Nodaviridae/genetics ; Nodaviridae/isolation & purification ; Pandalidae/virology ; Phylogeny ; RNA, Viral/genetics ; Shellfish/classification ; Shellfish/virology
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2022-02-06
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14020328
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Evidence of Atlantic bluefin tuna spawning in the Bay of Biscay, north‐eastern Atlantic

    Rodriguez, Jose M. / Johnstone, Carolina / Lozano‐Peral, Diego

    Journal of fish biology. 2021 Sept., v. 99, no. 3

    2021  

    Abstract: The spawning grounds of the Atlantic bluefin tuna (Thunnus thynnus) are traditionally considered to be the Gulf of Mexico (Gulf of Mexico) and the Mediterranean Sea (Mediterranean Sea). However, for the western Atlantic, unequivocal evidence of bluefin ... ...

    Abstract The spawning grounds of the Atlantic bluefin tuna (Thunnus thynnus) are traditionally considered to be the Gulf of Mexico (Gulf of Mexico) and the Mediterranean Sea (Mediterranean Sea). However, for the western Atlantic, unequivocal evidence of bluefin spawning outside the Gulf of Mexico has been shown. In this study we present the first records of genetically confirmed bluefin larvae in the southern Bay of Biscay (eastern Atlantic). These findings provide evidence of bluefin spawning activity outside the Mediterranean Sea, in the north‐eastern Atlantic. However, our results suggest that the bluefin spawning in the Bay of Biscay is a sporadic phenomenon.
    Keywords Thunnus thynnus ; fish ; Bay of Biscay ; Gulf of Mexico ; Mediterranean Sea
    Language English
    Dates of publication 2021-09
    Size p. 964-969.
    Publishing place Blackwell Publishing Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 410564-3
    ISSN 1095-8649 ; 0022-1112
    ISSN (online) 1095-8649
    ISSN 0022-1112
    DOI 10.1111/jfb.14782
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  9. Article: Matching an Old Marine Paradigm: Limitless Connectivity in a Deep-Water Fish over a Large Distance.

    Ferrari, Alice / Spiga, Martina / Rodriguez, Miriam Dominguez / Fiorentino, Fabio / Gil-Herrera, Juan / Hernandez, Pilar / Hidalgo, Manuel / Johnstone, Carolina / Khemiri, Sana / Mokhtar-Jamaï, Kenza / Nadal, Irene / Pérez, Montse / Sammartino, Simone / Vasconcellos, Marcelo / Cariani, Alessia

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 17

    Abstract: Investigations of population structuring in wild species are fundamental to complete the bigger picture defining their ecological and biological roles in the marine realm, to estimate their recovery capacity triggered by human disturbance and implement ... ...

    Abstract Investigations of population structuring in wild species are fundamental to complete the bigger picture defining their ecological and biological roles in the marine realm, to estimate their recovery capacity triggered by human disturbance and implement more efficient management strategies for fishery resources. The Blackspot Seabream (
    Language English
    Publishing date 2023-08-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13172691
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Family planning science and practice lessons from the 2018 International Conference on Family Planning.

    Rusatira, Jean Christophe / Silberg, Claire / Mickler, Alexandria / Salmeron, Carolina / Twahirwa Rwema, Jean Olivier / Johnstone, Maia / Martinez, Michelle / Rimon, Jose G / Zimmerman, Linnea

    Gates open research

    2021  Volume 4, Page(s) 43

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Journal Article
    ISSN 2572-4754
    ISSN (online) 2572-4754
    DOI 10.12688/gatesopenres.13130.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top