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  1. Article ; Online: A Novel Standardized Morbidity and Mortality Process to Promote Discourse, Improve Education, and Facilitate Practice Change: The M-PROVE Model.

    Bowman, Max / Yang, Heiko / Ahn, Justin / Carroll, Peter R / Hampson, Lindsay A

    Urology practice

    2023  Volume 10, Issue 4, Page(s) 391–397

    Abstract: Introduction: The morbidity and mortality conference is essential to medical education and quality improvement. Ideally, the conference is inclusive, judgment-free, and focused on practice improvement. In reality, it may not meet these goals. We ... ...

    Abstract Introduction: The morbidity and mortality conference is essential to medical education and quality improvement. Ideally, the conference is inclusive, judgment-free, and focused on practice improvement. In reality, it may not meet these goals. We reimagined the process by standardizing presentations and creating an oversight committee to improve the perceived value of the conference and identify opportunities for improvement. This study evaluates the subjective impact of the redesigned process at our institution and provides a blueprint for our reproducible model.
    Methods: We created a faculty and resident committee to review all submitted cases, implemented a standardized presentation template and moderating structure, and tracked quality improvement measures from proposed improvement initiatives. Attitudes toward the conference, including perceived quality/relevance, identification of potential systems changes, inclusiveness, and educational value, were assessed among faculty and trainees using pre- and postintervention Likert-style surveys.
    Results: Of 45 eligible department members, 41 (91%) completed the preintervention and 36 (80%) completed the postintervention survey. We found a statistically significant improvement in all questions between pre- and postintervention surveys except on the question about the conference environment being nonthreatening, which also improved but was not statistically significant. The overall average answer improved on the postintervention survey compared to the preintervention survey (3.36 vs 4.20,
    Conclusions: Redesigning and standardizing the morbidity and mortality conference with greater attention to education, inclusion, systems change, and quality improvement improves the attitudes of conference attendees and increases the perceived value of the conference.
    MeSH term(s) Quality Improvement ; Education, Medical ; Educational Status ; Clinical Competence ; Morbidity
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 2352-0787
    ISSN (online) 2352-0787
    DOI 10.1097/UPJ.0000000000000411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Performance of 'Gala' apple trees on supporter 4 and different strains of B.9, M.9, and M.26 rootstocks as part of the 2002 NC-140 apple rootstock trial

    Autio, W / Robinson, T.L / Cowgill, W / Hampson, C / Kushad, M / Lang, G / Masabni, J / Miller, D.D / Parra-Quezada, R.A / Perry, R / Rom, C

    Acta horticulturae. 2011 Aug., , no. 9031

    2011  

    Abstract: ... used in Europe), M.26 EMLA, M.26 NAKB, M.9 Burgmer 756, M.9 Nic 29, M.9 NAKBT337, and Supporter 4 ... Massachusetts, Michigan, New Jersey, New York, and Ohio. Trees were spaced 2.5×4.5 m and trained as vertical ... were significantly smaller than those on B.9 North America. Supporter 4, M.26 EMLA, M.26 NAKB, and M.9 ...

    Abstract In spring 2002, a North American-wide trial of apple rootstocks was established under the coordination of NC-140. ‘Buckeye Gala’ (Malus × domestica) was used as the scion cultivar, and rootstocks included B.9 North America (the strain commonly used in North America), B.9 Europe (the strain commonly used in Europe), M.26 EMLA, M.26 NAKB, M.9 Burgmer 756, M.9 Nic 29, M.9 NAKBT337, and Supporter 4. The trial was planted in Arkansas, British Columbia (Canada), Chihuahua (Mexico), Illinois, Kentucky, Massachusetts, Michigan, New Jersey, New York, and Ohio. Trees were spaced 2.5×4.5 m and trained as vertical axes. After six growing seasons, smallest trees were on the two B.9 strains and trees on B.9 Europe were significantly smaller than those on B.9 North America. Supporter 4, M.26 EMLA, M.26 NAKB, and M.9 Burgmer 756 were similar and resulted in the largest trees, followed by M.9 Nic 29 and M.9 NAKBT337, in descending trunk cross-sectional area. Trees on M.26 NAKB, M.26 EMLA, and Supporter 4 cumulatively (2004-07) yielded more than those on B.9 Europe. The most cumulatively yield efficient trees were on the two B.9 strains, significantly more than trees on any of the other rootstocks (all of which were similar). Over the 2004-07 fruiting life of the trial, rootstock did not affect fruit size.
    Keywords Aesculus ; Malus ; apples ; cultivars ; planting ; rootstocks ; scions ; spring ; trees ; Arkansas ; British Columbia ; Europe ; Illinois ; Kentucky ; Massachusetts ; Mexico ; Michigan ; New Jersey ; New York ; Ohio
    Language English
    Size p. 311-318.
    Publishing place International Society for Horticultural Science
    Document type Article
    Note Paper presented at the Ninth International Symposium on Integrating Canopy, Rootstock and Environmental Physiology in Orchard Systems, Volume 1, held August 4-8, 2008, Geneva, New York.
    ISSN 0567-7572
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Re: Evaluating the Role of Operative Repair of Extraperitoneal Bladder Rupture following Blunt Pelvic Trauma: N. V. Johnsen, J. B. Young, W. S. Reynolds, M. R. Kaufman, D. F. Milam, O. D. Guillamondegui and R. R. Dmochowski J Urol 2016;195:661-665.

    Hampson, Lindsay / Hagedorn, Judith / Voelzke, Bryan B

    The Journal of urology

    2016  Volume 196, Issue 3, Page(s) 963–965

    MeSH term(s) Abdominal Injuries ; Humans ; Pelvis ; Urinary Bladder Diseases ; Wounds, Nonpenetrating
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2016.04.058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: 2002 NC-140 Apple Rootstock Trial: Gala Apple Trees on Supporter 4, P. 14, and Different Strains of B.9, M.9 and M.26 Rootstocks Final Progress Report

    Autio, Wesley / Robinson, Terence / Archbold, Douglas / Cowgill, Winfred / Hampson, Cheryl / Quezada, Rafaelparra / Wolfe, Dwight

    Compact fruit tree

    2013  Volume 46, Issue 1, Page(s) 23

    Document type Article
    ZDB-ID 406565-7
    Database Current Contents Nutrition, Environment, Agriculture

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  5. Article ; Online: A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. Cook.

    Little, Annette S / Balmanno, Kathryn / Sale, Matthew J / Newman, Scott / Dry, Jonathan R / Hampson, Mark / Edwards, Paul A W / Smith, Paul D / Cook, Simon J

    Science signaling

    2011  Volume 4, Issue 170, Page(s) er2

    Abstract: The acquisition of resistance to protein kinase inhibitors is a growing problem in cancer treatment. We modeled acquired resistance to the MEK1/2 (mitogen-activated or extracellular signal–regulated protein kinase kinases 1 and 2) inhibitor selumetinib ( ... ...

    Abstract The acquisition of resistance to protein kinase inhibitors is a growing problem in cancer treatment. We modeled acquired resistance to the MEK1/2 (mitogen-activated or extracellular signal–regulated protein kinase kinases 1 and 2) inhibitor selumetinib (AZD6244) in colorectal cancer cell lines harboring mutations in BRAF (COLO205 and HT29 lines) or KRAS (HCT116 and LoVo lines). AZD6244-resistant derivatives were refractory to AZD6244-induced cell cycle arrest and death and exhibited a marked increase in ERK1/2 (extracellular signal–regulated kinases 1 and 2) pathway signaling and cyclin D1 abundance when assessed in the absence of inhibitor. Genomic sequencing revealed no acquired mutations in MEK1 or MEK2, the primary target of AZD6244. Rather, resistant lines showed a marked up-regulation of their respective driving oncogenes, BRAF600E or KRAS13D, due to intrachromosomal amplification. Inhibition of BRAF reversed resistance to AZD6244 in COLO205 cells, which suggested that combined inhibition of MEK1/2 and BRAF may reduce the likelihood of acquired resistance in tumors with BRAF600E. Knockdown of KRAS reversed AZD6244 resistance in HCT116 cells as well as reduced the activation of ERK1/2 and protein kinase B; however, the combined inhibition of ERK1/2 and phosphatidylinositol 3-kinase signaling had little effect on AZD6244 resistance, suggesting that additional KRAS effector pathways contribute to this process. Microarray analysis identified increased expression of an 18-gene signature previously identified as reflecting MEK1/2 pathway output in resistant cells. Thus, amplification of the driving oncogene (BRAF600E or KRAS13D) can drive acquired resistance to MEK1/2 inhibitors by increasing signaling through the ERK1/2 pathway. However, up-regulation of KRAS13D leads to activation of multiple KRAS effector pathways, underlining the therapeutic challenge posed by KRAS mutations. These results may have implications for the use of combination therapies.
    MeSH term(s) Benzimidazoles ; Cell Cycle/drug effects ; Cell Death/drug effects ; Cell Line, Tumor ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/enzymology ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Drug Resistance, Neoplasm/genetics ; Gene Amplification ; Genes, ras ; Humans ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/genetics ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Phosphatidylinositol 3-Kinases/antagonists & inhibitors ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras) ; Up-Regulation ; ras Proteins/genetics
    Chemical Substances AZD 6244 ; Benzimidazoles ; KRAS protein, human ; Proto-Oncogene Proteins ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2) ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2) ; ras Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2011-06-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Corrected and Republished Article
    ZDB-ID 2417226-1
    ISSN 1937-9145 ; 1945-0877
    ISSN (online) 1937-9145
    ISSN 1945-0877
    DOI 10.1126/scisignal.4170er2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: M-band nonlinear subband decompositions with perfect reconstruction.

    Hampson, F J / Pesquet, J C

    IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

    1998  Volume 7, Issue 11, Page(s) 1547–1560

    Abstract: We investigate nonlinear multirate filterbanks with maximal decimation and perfect reconstruction. Definitions of the desired properties of such structures are given for general nonlinear filterbanks. We then consider a triangular representation of ... ...

    Abstract We investigate nonlinear multirate filterbanks with maximal decimation and perfect reconstruction. Definitions of the desired properties of such structures are given for general nonlinear filterbanks. We then consider a triangular representation of linear filterbanks and see that it may be easily extended to the nonlinear case. Furthermore, general nonlinear filterbanks are presented, for which perfect reconstruction is either inherently guaranteed or ensured subject to an easily verified condition. Extensions to bidimensional filters are also discussed and an application for nonlinear multiresolution schemes to feature sieves is shown.
    Language English
    Publishing date 1998
    Publishing country United States
    Document type Journal Article
    ISSN 1057-7149
    ISSN 1057-7149
    DOI 10.1109/83.725362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: AUTHOR REPLY.

    Hampson, Lindsay A / Shaw, Nathan M

    Urology

    2023  Volume 177, Page(s) 195–196

    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2022.12.073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Editorial Commentary.

    Shaw, Nathan M / Hampson, Lindsay A

    Urology practice

    2023  Volume 10, Issue 2, Page(s) 144–145

    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Journal Article
    ISSN 2352-0787
    ISSN (online) 2352-0787
    DOI 10.1097/UPJ.0000000000000369.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: More than being dry: what bothers men with stress urinary incontinence after prostate cancer therapy.

    Shaw, Nathan M / Hampson, Lindsay A

    Translational andrology and urology

    2023  Volume 12, Issue 10, Page(s) 1617–1618

    Language English
    Publishing date 2023-10-05
    Publishing country China
    Document type Journal Article
    ZDB-ID 2851630-8
    ISSN 2223-4691 ; 2223-4691 ; 2223-4683
    ISSN (online) 2223-4691
    ISSN 2223-4691 ; 2223-4683
    DOI 10.21037/tau-2023-03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Editorial Comment.

    Bowman, Max / Hampson, Lindsay A

    Urology practice

    2023  Volume 11, Issue 2, Page(s) 252

    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2352-0787
    ISSN (online) 2352-0787
    DOI 10.1097/UPJ.0000000000000511.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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