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  1. Buch ; Online: Nanomaterials Based Gas Sensors for SF6 Decomposition Components Detection

    Zhang, Xiaoxing / Tang, Ju / Xiao, Song / Zeng, Fuping / Pan, Cheng / Gui, Yingang / Zeng, Fuping

    2017  

    Schlagwörter Condensed matter physics (liquid state & solid state physics) ; carbon nanotubes, density functional theory, graphene, adsorption, sensing mechanism
    Sprache Englisch
    Umfang 1 electronic resource (158 pages)
    Verlag IntechOpen
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030644731
    ISBN 9789535148098 ; 9535148095
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Artikel: Efficacy of

    Li, Qing / Pei, Ronghong / Chen, Erbao / Zheng, Fuping / Zhang, Yuhang / Meng, Shihao

    Heliyon

    2024  Band 10, Heft 4, Seite(n) e26167

    Abstract: Jiuzao, ...

    Abstract Jiuzao,
    Sprache Englisch
    Erscheinungsdatum 2024-02-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26167
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Fine-Scale Genetic Structure of

    Zhang, Li / Wang, Fuping / Wu, Jiaxi / Ye, Sicheng / Xu, Ye / Liu, Yanan

    Insects

    2024  Band 15, Heft 2

    Abstract: The Camellia weevil, ...

    Abstract The Camellia weevil,
    Sprache Englisch
    Erscheinungsdatum 2024-02-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects15020116
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: A Novel Regulator PepR Regulates the Expression of Dipeptidase Gene

    Zhang, Xin / Wang, Hengjie / Yan, Tinglu / Chen, Yuhan / Peng, Qi / Song, Fuping

    Microorganisms

    2024  Band 12, Heft 3

    Abstract: ... Bacillus ... ...

    Abstract Bacillus thuringiensis
    Sprache Englisch
    Erscheinungsdatum 2024-03-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12030579
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Recent progress in nanomaterials for bacteria-related tumor therapy.

    Zhang, Fuping / Wang, Shuyu / Yang, Shuo / Ma, Feihe / Gao, Hui

    Biomaterials science

    2024  Band 12, Heft 8, Seite(n) 1965–1980

    Abstract: Many studies suggest that tumor microbiome closely relates to the oncogenesis and anti-tumor responses in multiple cancer types ( ...

    Abstract Many studies suggest that tumor microbiome closely relates to the oncogenesis and anti-tumor responses in multiple cancer types (
    Mesh-Begriff(e) Humans ; Bacteria ; Lung Neoplasms ; Pancreatic Neoplasms ; Cell Transformation, Neoplastic ; Nanostructures/therapeutic use
    Sprache Englisch
    Erscheinungsdatum 2024-04-16
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2693928-9
    ISSN 2047-4849 ; 2047-4830
    ISSN (online) 2047-4849
    ISSN 2047-4830
    DOI 10.1039/d3bm01952g
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Brazilin-7-2-butenoate inhibits amyloid β-protein aggregation, alleviates cytotoxicity, and protects Caenorhabditis elegans.

    Cui, Zhan / Qu, Lili / Zhang, Qingfu / Lu, Fuping / Liu, Fufeng

    International journal of biological macromolecules

    2024  Band 264, Heft Pt 2, Seite(n) 130695

    Abstract: The fibrillogenesis of amyloid β-protein (Aβ) gradually accumulates to form neurotoxic Aβ aggregates in the human brain, which is the direct cause of Alzheimer's disease (AD) related symptoms. There are currently no effective therapies for AD. Brazilin, ... ...

    Abstract The fibrillogenesis of amyloid β-protein (Aβ) gradually accumulates to form neurotoxic Aβ aggregates in the human brain, which is the direct cause of Alzheimer's disease (AD) related symptoms. There are currently no effective therapies for AD. Brazilin, a natural polyphenol, inhibits Aβ fibrillogenesis, disrupts the mature fibrils and alleviates the corresponding cytotoxicity, but it also has the high toxic. Therefore, brazilin-7-2-butenoate (B-7-2-B), a brazilin derivative, was designed and synthesized. B-7-2-B exhibited lower toxicity and stronger inhibitory effect on Aβ aggregation than brazilin. B-7-2-B could prevent the formation of Aβ fibrils and oligomers, and depolymerize pre-formed aggregates in a dose-dependent manner. Furthermore, B-7-2-B prominently alleviated the cytotoxicity and the oxidative stress induced by Aβ aggregates in PC12 cells. The protective impacts of B-7-2-B were further demonstrated by using the Caenorhabditis elegans model, including decreasing the extent of Aβ aggregation, improving the motility and sensation disorders. Eventually, B-7-2-B was proven to be no apparent damage to worms. In summarize, it can be concluded that B-7-2-B has the potential as a drug for treating AD.
    Mesh-Begriff(e) Animals ; Rats ; Humans ; Amyloid beta-Peptides/toxicity ; Caenorhabditis elegans ; Benzopyrans/pharmacology ; PC12 Cells ; Alzheimer Disease/drug therapy ; Amyloid
    Chemische Substanzen Amyloid beta-Peptides ; brazilin (FZ39SW1K10) ; Benzopyrans ; Amyloid
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.130695
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Transcriptional regulation of cellobiose utilization by PRD-domain containing Sigma54-dependent transcriptional activator (CelR) and catabolite control protein A (CcpA) in

    Zhang, Liangwei / Xu, Hong / Cheng, Haijian / Song, Fuping / Zhang, Jie / Peng, Qi

    Frontiers in microbiology

    2024  Band 15, Seite(n) 1160472

    Abstract: Cellobiose, a β-1,4-linked glucose dimer, is a major cellodextrin resulting from the enzymatic hydrolysis of cellulose. It is a major source of carbon for soil bacteria. In bacteria, the phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system ( ... ...

    Abstract Cellobiose, a β-1,4-linked glucose dimer, is a major cellodextrin resulting from the enzymatic hydrolysis of cellulose. It is a major source of carbon for soil bacteria. In bacteria, the phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS), encoded by the
    Sprache Englisch
    Erscheinungsdatum 2024-01-31
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1160472
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Identification and investigation of the effects of N-acetylmuramoyl-L-alanine amidase in Bacillus amyloliquefaciens for the cell lysis and heterologous protein production.

    Zhang, Jinfang / Lu, Fuping / Li, Mei

    International journal of biological macromolecules

    2023  Band 256, Heft Pt 2, Seite(n) 128468

    Abstract: Bacillus amyloliquefaciens (BA) is considered as an important industrial strain for heterologous proteins production. However, its severe autolytic behavior leads to reduce the industrial production capacity of the chassis cells. In this study, we aimed ... ...

    Abstract Bacillus amyloliquefaciens (BA) is considered as an important industrial strain for heterologous proteins production. However, its severe autolytic behavior leads to reduce the industrial production capacity of the chassis cells. In this study, we aimed to evaluate the autolysis of N-acetylmuranyl-L-alanine amidase in BA TCCC11018, and further slowed down the cell lysis for improved the heterologous protein production by a series of modifications. Firstly, we identified six N-acetylmuramic acid-L-alanines by bioinformatics, and analyzed the transcriptional levels at different culture time points by transcriptome and quantitative real-time PCR. Then, by establishing an efficient CRISPR-nCas9 gene editing method, N-acetylmuramic acid-L-alanine genes were knocked out or overexpressed to verify its effect on cell lysis. Then, by single or tandem knockout N-acetylmuramic acid-L-alanines, it was determined that the reasonable modification of LytH and CwlC1 can slow down cell lysis. After 48 h of culture, the autolysis rate of the mutant strain BA ΔlytH-cwlC1 decreased by 4.83 %, and the amylase activity reached 176 U/mL, which was 76.04 % higher than that of the control strain BA Δupp. The results provide a reference for mining the functional characteristics of autolysin in Bacillus spp., and provide from this study reveal valuable insights delaying the cell lysis and increasing heterologous proteins production.
    Mesh-Begriff(e) N-Acetylmuramoyl-L-alanine Amidase/genetics ; N-Acetylmuramoyl-L-alanine Amidase/metabolism ; Bacillus amyloliquefaciens/genetics ; Bacillus amyloliquefaciens/metabolism ; Muramic Acids ; Alanine
    Chemische Substanzen N-Acetylmuramoyl-L-alanine Amidase (EC 3.5.1.28) ; N-acetylmuramic acid (246FXU111L) ; Muramic Acids ; Alanine (OF5P57N2ZX)
    Sprache Englisch
    Erscheinungsdatum 2023-11-29
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.128468
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Inhibitory Effects of

    Li, Qing / Wu, Liling / Wang, Guangnan / Zheng, Fuping / Sun, Jinyuan / Zhang, Yuhang / Li, Zexia / Li, Lianghao / Sun, Baoguo

    Foods (Basel, Switzerland)

    2024  Band 13, Heft 2

    Abstract: The liver is critical in alcohol metabolism, and excessive consumption heightens the risk of hepatic damage, potentially escalating to hepatitis and cirrhosis. ...

    Abstract The liver is critical in alcohol metabolism, and excessive consumption heightens the risk of hepatic damage, potentially escalating to hepatitis and cirrhosis.
    Sprache Englisch
    Erscheinungsdatum 2024-01-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13020276
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Bacillus coagulans

    Shi, Qingying / Yang, Chen / Zhang, Bingjie / Chen, Dongxiao / Lu, Fuping / Zhao, Huabing

    Foods (Basel, Switzerland)

    2022  Band 11, Heft 21

    Abstract: Titanium dioxide nanoparticles ( ... ...

    Abstract Titanium dioxide nanoparticles (TiO
    Sprache Englisch
    Erscheinungsdatum 2022-10-26
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods11213368
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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