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  1. Article: Pulmonary Embolism in COVID-19 Pneumonia: An Overlapping Diagnosis or a Misdiagnosis?

    Secco, Eleonora / Pasqualetto, Maria Cristina / Rigo, Fausto

    Journal of cardiovascular echography

    2020  Volume 30, Issue 2, Page(s) 110–112

    Abstract: Coronavirus pneumonia (COVID-19) is a novel infectious disease with a high mortality rate due to severe acute respiratory syndrome. A 57-year-old woman was admitted to the emergency department (ED) with fever, cough, atypical chest pain, and dyspnea. She ...

    Abstract Coronavirus pneumonia (COVID-19) is a novel infectious disease with a high mortality rate due to severe acute respiratory syndrome. A 57-year-old woman was admitted to the emergency department (ED) with fever, cough, atypical chest pain, and dyspnea. She remained in the ED for about 48 h while waiting for the result of the COVID-19 oropharyngeal swab. Once she tested positive, she was hospitalized in the pneumological department with a diagnosis of pneumonia based on a chest X-ray and biochemical tests. Although azithromycin and hydroxychloroquine were promptly administered, she had a worsening of dyspnea even with a high-flow oxygen mask. D-dimer was increased, and a computed tomography scan with pulmonary and leg angiogram was positive for bilateral pulmonary embolism, deep-venous thrombosis, and multiple consolidated opacities in the lung parenchyma. This case highlights the fact that, in a pandemic situation, there is a potentially fatal risk of overlooking an alternative diagnosis in a COVID-19 patient who is generally considered as suffering only from pneumonia.
    Language English
    Publishing date 2020-08-17
    Publishing country India
    Document type Case Reports
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/jcecho.jcecho_43_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Pulmonary Embolism in COVID-19 Pneumonia: An Overlapping Diagnosis or a Misdiagnosis?

    Secco, Eleonora / Pasqualetto, Maria Cristina / Rigo, Fausto

    Journal of Cardiovascular Echography

    Abstract: Coronavirus pneumonia (COVID-19) is a novel infectious disease with a high mortality rate due to severe acute respiratory syndrome A 57-year-old woman was admitted to the emergency department (ED) with fever, cough, atypical chest pain, and dyspnea She ... ...

    Abstract Coronavirus pneumonia (COVID-19) is a novel infectious disease with a high mortality rate due to severe acute respiratory syndrome A 57-year-old woman was admitted to the emergency department (ED) with fever, cough, atypical chest pain, and dyspnea She remained in the ED for about 48 h while waiting for the result of the COVID-19 oropharyngeal swab Once she tested positive, she was hospitalized in the pneumological department with a diagnosis of pneumonia based on a chest X-ray and biochemical tests Although azithromycin and hydroxychloroquine were promptly administered, she had a worsening of dyspnea even with a high-flow oxygen mask D-dimer was increased, and a computed tomography scan with pulmonary and leg angiogram was positive for bilateral pulmonary embolism, deep-venous thrombosis, and multiple consolidated opacities in the lung parenchyma This case highlights the fact that, in a pandemic situation, there is a potentially fatal risk of overlooking an alternative diagnosis in a COVID-19 patient who is generally considered as suffering only from pneumonia
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #796822
    Database COVID19

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  3. Article ; Online: A possible benefit from therapeutic anticoagulation in patients with coronavirus disease 2019: the Dolo hospital experience in Veneto, Italy.

    Secco, Eleonora / Pasqualetto, Maria Cristina / Bombardini, Tonino / Picano, Eugenio / Rigo, Fausto

    Kardiologia polska

    2020  Volume 78, Issue 9, Page(s) 919–921

    MeSH term(s) Aged ; Anticoagulants/therapeutic use ; COVID-19 ; Coronavirus/drug effects ; Coronavirus Infections/drug therapy ; Female ; Humans ; Italy ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/drug therapy ; Treatment Outcome
    Chemical Substances Anticoagulants
    Keywords covid19
    Language English
    Publishing date 2020-07-06
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.15489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Transient Type 1 Brugada Pattern without Ongoing Fever during COVID-19 Pneumonia.

    Pasqualetto, Maria Cristina / Corrado, Andrea / Secco, Eleonora / Graceffa, Fabio / Rigo, Fausto

    European journal of case reports in internal medicine

    2020  Volume 7, Issue 7, Page(s) 1808

    Abstract: Patients with COVID-19 pneumonia can develop heart problems and may also may be susceptible to proarrhythmia, virus-related issues such as fever, stress, electrolyte disturbance and adverse effects from the use of antiviral drugs. We report a transient ... ...

    Abstract Patients with COVID-19 pneumonia can develop heart problems and may also may be susceptible to proarrhythmia, virus-related issues such as fever, stress, electrolyte disturbance and adverse effects from the use of antiviral drugs. We report a transient Brugada-like ECG pattern without ongoing fever in a 57-year-old man, admitted with a diagnosis of COVID-19 pneumonia, who did not have syncope or a family history of sudden cardiac death.
    Learning points: Patients with COVID-19 pneumonia can develop heart problems.A transient Brugada-like ECG pattern was observed in a non-febrile COVID-19 patient.SARS-CoV-2 may have a direct effect on myocardial ion channels.
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2020_001808
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transient Type 1 Brugada Pattern without Ongoing Fever during COVID-19 Pneumonia

    Maria Cristina Pasqualetto / Andrea Corrado / Eleonora Secco / Fabio Graceffa / Fausto Rigo

    European Journal of Case Reports in Internal Medicine (2020)

    2020  

    Abstract: Patients with COVID-19 pneumonia can develop heart problems and may also may be susceptible to proarrhythmia, virus-related issues such as fever, stress, electrolyte disturbance and adverse effects from the use of antiviral drugs. We report a transient ... ...

    Abstract Patients with COVID-19 pneumonia can develop heart problems and may also may be susceptible to proarrhythmia, virus-related issues such as fever, stress, electrolyte disturbance and adverse effects from the use of antiviral drugs. We report a transient Brugada-like ECG pattern without ongoing fever in a 57-year-old man, admitted with a diagnosis of COVID-19 pneumonia, who did not have syncope or a family history of sudden cardiac death.
    Keywords brugada pattern ; covid-19 ; fever ; myocardial ion channels ; Medicine ; R ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Stress Cardiomyopathy in COVID-19 Disease.

    Pasqualetto, Maria Cristina / Secco, Eleonora / Nizzetto, Manuele / Scevola, Moreno / Altafini, Lorella / Cester, Alberto / Rigo, Fausto

    European journal of case reports in internal medicine

    2020  Volume 7, Issue 6, Page(s) 1718

    Abstract: Patients affected by COVID-19 pneumonia may develop stress cardiomyopathy, also known as Takotsubo syndrome (TTS), at different stages during the disease and with different degrees of left ventricular dysfunction. We describe three cases of TTS in COVID- ... ...

    Abstract Patients affected by COVID-19 pneumonia may develop stress cardiomyopathy, also known as Takotsubo syndrome (TTS), at different stages during the disease and with different degrees of left ventricular dysfunction. We describe three cases of TTS in COVID-19-positive patients with different clinical presentations and outcomes. One of them died, while in the other two coronary angiography confirmed the diagnosis but was postponed until after pneumonia resolution because of the risk of virus spread.
    Learning points: An association between COVID-19 and cardiac involvement is highlighted.The incidence of Takotsubo syndrome has increased during this pandemic, possibly because it is caused by acute stress.
    Keywords covid19
    Language English
    Publishing date 2020-05-15
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2020_001718
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A possible benefit from therapeutic anticoagulation in patients with coronavirus disease 2019: the Dolo hospital experience in Veneto, Italy

    Secco, Eleonora / Pasqualetto, Maria Cristina / Bombardini, Tonino / Picano, Eugenio / Rigo, Fausto

    Kardiol Pol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #633631
    Database COVID19

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  8. Article ; Online: Safety of surgical masks during physical activity evaluated with graded cycle ergometry test.

    Pasqualetto, M Cristina / Tuttolomondo, Domenico / Gaibazzi, Nicola / Baratella, M Cristina / Casolino, Pietro / Stefani, Maria / Reato, Stefania / Tattan, Elisa / Sorbo, Maria D / Bigon, Lucio / Giada, Franco / Nizzetto, Manuele / Ferrara, Chiara / Galiotto, Alessandra / Scevola, Moreno / Rigo, Fausto

    The Journal of sports medicine and physical fitness

    2021  Volume 62, Issue 6, Page(s) 846–850

    Abstract: Background: At the time of the coronavirus disease 2019 (COVID-19) pandemic wearing surgical mask (SM) is recommended for the prevention of contracting or exposing others to airborne transmission of COVID-19. It is somewhat controversial whether wearing ...

    Abstract Background: At the time of the coronavirus disease 2019 (COVID-19) pandemic wearing surgical mask (SM) is recommended for the prevention of contracting or exposing others to airborne transmission of COVID-19. It is somewhat controversial whether wearing SM during exercise affects performance and health status and/or may influence the results. In order to give an answer we planned a prospective, randomized, crossover study to evaluate the effects of wearing a SM or no-SM in 33 (17 male) physically active healthy subjects during a graded exercise cycle ergometry test.
    Methods: The two tests were performed in random order in the same subjects. The participants were all tested the same day, after a recovery time of at least of one hour, in order to avoid interferences on physical performances. Arterial oxygen saturation, heart rate and arterial blood pressure were assessed throughout the exercise tests every step of two minutes, at the end of exercise, performed at the same time with and without mask.
    Results: Wearing SM had no effect on performance, since the duration of cycle ergometry test with SM and without SM median, respectively, was 14.2 (lower-upper quartile 13.9-14.8) versus 14.3 (13.9-15.5) minutes (P=0.094), and median peak power was 150 W (150-180) versus 150 W (120-180) (P=0.754).
    Conclusions: When expressed relative to peak exercise performance, no differences were found between wearing or not wearing SM regarding arterial oxygen saturation, or heart rate at any time during the exercise tests. Wearing SM during vigorous exercise had no detrimental effect on cardiovascular parameters, as well as on exercise metrics in all participants. No ventricular repolarization abnormalities and no arrhythmias were reported on the electrocardiograms.
    MeSH term(s) COVID-19/prevention & control ; Cross-Over Studies ; Exercise/physiology ; Exercise Test ; Humans ; Male ; Masks ; Prospective Studies
    Language English
    Publishing date 2021-10-15
    Publishing country Italy
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 410823-1
    ISSN 1827-1928 ; 0022-4707
    ISSN (online) 1827-1928
    ISSN 0022-4707
    DOI 10.23736/S0022-4707.21.12814-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pulmonary embolism in COVID-19 pneumonia

    Secco, Eleonora / Pasqualetto, MariaCristina / Rigo, Fausto

    Journal of Cardiovascular Echography

    An overlapping diagnosis or a misdiagnosis?

    2020  Volume 30, Issue 2, Page(s) 110

    Keywords covid19
    Language English
    Publisher Medknow
    Publishing country in
    Document type Article ; Online
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/jcecho.jcecho_43_20
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems.

    Pasqualetto, Maria Cristina / Sorbo, Maria Domenica / Vitiello, Maria / Ferrara, Chiara / Scevola, Moreno / Pantalone, Fabio / Gelain, Fabio / Aloi, Claudio / Nizzetto, Manuele / Rigo, Fausto

    European journal of case reports in internal medicine

    2020  Volume 7, Issue 12, Page(s) 2160

    Abstract: A patient affected by COVID-19 pneumonia may develop pulmonary hypertension (PH) and secondary right ventricular (RV) involvement, due to lung parenchymal and interstitial damage and altered pulmonary haemodynamics, even in non-advanced phases of the ... ...

    Abstract A patient affected by COVID-19 pneumonia may develop pulmonary hypertension (PH) and secondary right ventricular (RV) involvement, due to lung parenchymal and interstitial damage and altered pulmonary haemodynamics, even in non-advanced phases of the disease. This is a consequence of hypoxic vasoconstriction of the pulmonary circulation, the use of positive end-expiratory pressure (PEEP) in mechanical ventilation, pulmonary endothelial injury, and local inflammatory thrombotic and/or thromboembolic processes. We report the case of a young man admitted with a diagnosis of COVID-19 pneumoniae with PH unrelated to viral infection and in whom partial anomalous pulmonary venous drainage (PAPVD) was eventually diagnosed.
    Learning points: COVID-19 patients, even if previously well, can have pulmonary hypertension due to other causes.The cause of pulmonary hypertension should always be sought and not assumed, even in COVID-19 patients.
    Language English
    Publishing date 2020-12-11
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2020_002160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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