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Article ; Online: Intraoperative neurophysiological mapping of trigeminal nerve: A surgical advancement in neurovascular decompression.

Sanabria Duarte, Joel / Benzecry de Almeida, Daniel / Arcie, Gabriella Mara / Coelho Neto, Mauricio / Sousa de Meneses, Murilo / Ramina, Ricardo

World neurosurgery: X

2024 Volume 22, Page(s) 100359

Language	English
Publishing date	2024-03-02
Publishing country	United States
Document type	Journal Article
ISSN	2590-1397
ISSN (online)	2590-1397
DOI	10.1016/j.wnsx.2024.100359
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Article: Elucidating the Mechanisms of Pulsed Radiofrequency for Pain Treatment.

De la Cruz, Jonathan / Benzecry Almeida, Daniel / Silva Marques, Mayara / Ramina, Ricardo / Fortes Kubiak, Rodolfo Jorge

Cureus

2023 Volume 15, Issue 9, Page(s) e44922

Abstract: Pulsed radiofrequency is a well-documented treatment option for multiple painful conditions where pulses of energy are delivered close to neural elements. Since its earliest adoption, this technique has gained increasing acceptance as a minimally ... ...

Abstract	Pulsed radiofrequency is a well-documented treatment option for multiple painful conditions where pulses of energy are delivered close to neural elements. Since its earliest adoption, this technique has gained increasing acceptance as a minimally invasive procedure, and new applications are evolving. Studies have shown microscopic and biochemical changes that reflect beneficial effects; however, the exact mechanism of action is not yet completely understood. To redress this paucity, 11,476 articles of scientific relevance published between 1980 and November 2022 were mined through a search of the PubMed database, arriving at 49 studies both in animals and humans. In general, the experimental studies examined have shown that pulsed radiofrequency induces multiple changes with antinociceptive and neuromodulatory effects. These modifications include changes in neural and glial cells, synaptic transmission, and perineural space. Studies also reveal that pulsed radiofrequency regulates inflammatory responses, cellular signaling proteins, and the expression of genes related to pain transmission, acting in biological processes in structures such as myelin, mitochondria, axons, glial cells, connective tissue, regulation of proteins, ion channels, and neurotransmitters.
Language	English
Publishing date	2023-09-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.44922
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Article ; Online: Endoscopic lumbar sympathectomy as a treatment option for primary erythromelalgia - case report and review.

Loureiro, Marcelo de Paula / Novais, Pietro Maran / Paulin, João Augusto Nocera / de Almeida, Daniel Benzecry / de Lemos, Arlindo Nascimento

Jornal vascular brasileiro

2023 Volume 22, Page(s) e20220095

Abstract: Erythromelalgia is a rare disease, involving pain, edema, redness, and hyperthermia in the limbs. It is extremely refractory to drugs, has no defined treatment, and causes psychological comorbidities in the patient. We describe a case of erythromelalgia ... ...

Abstract	Erythromelalgia is a rare disease, involving pain, edema, redness, and hyperthermia in the limbs. It is extremely refractory to drugs, has no defined treatment, and causes psychological comorbidities in the patient. We describe a case of erythromelalgia involving a 17-year-old boy who had been suffering from the disease for almost 4 years prior to finding an effective treatment. A bilateral endoscopic lumbar sympathectomy was performed, limited to L2 and L3 resections. Four weeks after the procedure, the patient's symptoms were significantly mitigated and at 8 months follow-up he remained almost asymptomatic. Endoscopic lumbar sympathectomy was an effective treatment for primary erythromelalgia in this teenager, with exceptional reduction of his symptoms.
Language	English
Publishing date	2023-03-10
Publishing country	Brazil
Document type	Case Reports
ZDB-ID	2571403-X
ISSN	1677-7301 ; 1677-7301
ISSN (online)	1677-7301
ISSN	1677-7301
DOI	10.1590/1677-5449.202200952
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Article: A patient with posterior cortical atrophy due to Alzheimer's disease.

de Souza, Ricardo Krause Martinez / Grinberg, Lea Tenenholz / Josviak, Nalini Drieli / de Almeida, Daniel Benzecry / Ramina, Ricardo / Kowacs, Pedro André / Caramelli, Paulo

Dementia & neuropsychologia

2018 Volume 12, Issue 3, Page(s) 326–328

Language	English
Publishing date	2018-11-07
Publishing country	Brazil
Document type	Case Reports
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/1980-57642018dn12-030015
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Article ; Online: Clinical and Acoustic Alterations of Swallowing in Children Exposed to Zika Virus during Pregnancy in a Cohort in Amazonas, Brazil: A Case Series Study.

Rodrigues, Cristina de Souza / Souza, Raillon Keven Santos / Rocha Neto, Cosmo Vieira / Otani, Rodrigo Haruo / Batista, Daniel de Medeiros / Maia, Ana Karla Nelson de Oliveira / Filho, Kleber Pinheiro de Oliveira / Andrade, Thais Dourado de / Andrade Almeida, Emmilyn de / Maciel, Luiz Henrique Gonçalves / Castro, Lucíola de Fátima Albuquerque Almeida Peixoto / Abtibol-Bernardino, Marília Rosa / Baia-da-Silva, Djane Clarys / Benzecry, Silvana Gomes / Castilho, Marcia da Costa / Martínez-Espinosa, Flor Ernestina / Alecrim, Maria das Graças Costa / Santos, Rosane Sampaio / Botto-Menezes, Camila

Viruses

2023 Volume 15, Issue 12

Abstract: Oropharyngeal dysphagia (OD) is a swallowing disorder that involves difficulty in safely passing the food bolus from the oral cavity to the stomach. OD is a common problem in children with congenital Zika virus syndrome (CZS). In this case series, we ... ...

Abstract	Oropharyngeal dysphagia (OD) is a swallowing disorder that involves difficulty in safely passing the food bolus from the oral cavity to the stomach. OD is a common problem in children with congenital Zika virus syndrome (CZS). In this case series, we describe the clinical and acoustic alterations of swallowing in children exposed to the Zika virus during pregnancy in a cohort from Amazonas, Brazil. From July 2019 to January 2020, 22 children were evaluated, 6 with microcephaly and 16 without microcephaly. The mean age among the participants was 35 months (±4.6 months). All children with microcephaly had alterations in oral motricity, mainly in the lips and cheeks. Other alterations were in vocal quality, hard palate, and soft palate. Half of the children with microcephaly showed changes in cervical auscultation during breast milk swallowing. In children without microcephaly, the most frequently observed alteration was in lip motricity, but alterations in auscultation during the swallowing of breast milk were not observed. Regarding swallowing food of a liquid and pasty consistency, the most frequent alterations were incomplete verbal closure, increased oral transit time, inadequacy in capturing the spoon, anterior labial leakage, and increased oral transit time. Although these events are more frequent in microcephalic children, they can also be seen in non-microcephalic children, which points to the need for an indistinct evaluation of children exposed in utero to ZIKV.
MeSH term(s)	Pregnancy ; Child ; Female ; Humans ; Infant ; Child, Preschool ; Zika Virus ; Zika Virus Infection/complications ; Zika Virus Infection/congenital ; Pregnancy Complications, Infectious ; Microcephaly ; Deglutition ; Brazil/epidemiology ; Nervous System Malformations
Language	English
Publishing date	2023-11-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v15122363
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Article ; Online: Gamma knife radiosurgery for trigeminal neuralgia: first case series from Latin America.

Constanzo, Felipe / Silva, Rodrigo Souza da / de Almeida, Daniel Benzecry / Ferragut, Maria Alice / Coelho Neto, Mauricio / Toledo, Hugo Veroneze / Ramina, Ricardo

Arquivos de neuro-psiquiatria

2019 Volume 77, Issue 4, Page(s) 232–238

Abstract: Introduction: Gamma Knife® radiosurgery (GKRS) for trigeminal neuralgia is an effective treatment with at least a 50% reduction of pain in 75-95% of patients.: Objective: To present the first series of patients treated for trigeminal neuralgia using ... ...

Abstract	Introduction: Gamma Knife® radiosurgery (GKRS) for trigeminal neuralgia is an effective treatment with at least a 50% reduction of pain in 75-95% of patients. Objective: To present the first series of patients treated for trigeminal neuralgia using GKRS in Latin America. Methods: Retrospective analysis. Analysis consisted of time to improvement of symptoms, best Barrow Neurological Institute scale (BNI) score after procedure, time without pain, time to recurrence and post-procedural hypoesthesia. Results: Nineteen cases of classical trigeminal neuralgia were analyzed and three cases of symptomatic trigeminal neuralgia were described. Mean time from symptom onset to radiosurgery was 99.6 months, and 78.9% of patients had undergone invasive procedures before treatment. Patients were followed for a mean of 21.7 months. BNI I was achieved in 36.8%, IIIa in 21.1%, IIIb in 21.1%, IV in 5.3% and V in 15.7%. New hypoesthesia developed in 12.1% patients, which was associated with achieving BNI I after the procedure (p < 0.05). Time from diagnosis to GKRS was higher in patients who failed to achieve BNI I (143 vs. 76 months). The distance from the root entry zone in patients who achieved BNI I was greater than patients who did not (1.94 vs. 1.14 mm). Mean distance from the root entry zone in patients with new hypoesthesia was 2.85 mm vs. 1.06 mm (p = 0.06). Conclusion: Clinical response to GKRS is related to the time between diagnosis and procedure, thus its indication should be considered early in the management of these patients.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Dose-Response Relationship, Radiation ; Female ; Follow-Up Studies ; Humans ; Latin America ; Male ; Middle Aged ; Pain Measurement ; Radiosurgery/methods ; Recurrence ; Reproducibility of Results ; Retrospective Studies ; Rhizotomy/methods ; Time Factors ; Treatment Outcome ; Trigeminal Neuralgia/radiotherapy
Language	English
Publishing date	2019-05-15
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	418916-4
ISSN	1678-4227 ; 0004-282X
ISSN (online)	1678-4227
ISSN	0004-282X
DOI	10.1590/0004-282X20190027
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Article ; Online: Alternative option for osteogenesis imperfecta and trigeminal neuralgia.

Ruschel, Leonardo Gilmone / Agnoletto, Guilherme José / Hunhevicz, Sonival Cândido / Almeida, Daniel Benzecry de / Arruda, Walter Oleschko

Revista da Associacao Medica Brasileira (1992)

2017 Volume 63, Issue 4, Page(s) 307–310

Abstract: Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, ... ...

Abstract	Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, given distorted anatomy and deformities. We present an alternative option, consisting in cannulation of the foramen ovale and classical percutaneous treatment. Percutaneous balloon microcompression was performed in a 28 year-old woman with OI and severe trigeminal neuralgia using computed tomography (CT) and radiographic-guided cannulation of the Gasserian ganglion without neuronavigation or stereotactic devices. The patient developed hypoesthesia on the left V1, V2 and V3 segments with good pain control. This alternative technique with a CT-guided puncture, using angiosuite without the need of any Mayfield clamp, neuronavigation systems, frame or frameless stereotactic devices can be a useful, safe and efficient alternative for patients with trigeminal neuralgia with other bone deforming diseases that severely affect the skull base.
MeSH term(s)	Adult ; Angiography ; Catheterization/methods ; Female ; Foramen Ovale/diagnostic imaging ; Foramen Ovale/surgery ; Humans ; Osteogenesis Imperfecta/diagnostic imaging ; Osteogenesis Imperfecta/surgery ; Reproducibility of Results ; Tomography, X-Ray Computed ; Treatment Outcome ; Trigeminal Neuralgia/diagnostic imaging ; Trigeminal Neuralgia/surgery
Language	English
Publishing date	2017-04
Publishing country	Brazil
Document type	Case Reports
ZDB-ID	2027973-5
ISSN	1806-9282 ; 0104-4230
ISSN (online)	1806-9282
ISSN	0104-4230
DOI	10.1590/1806-9282.63.04.307
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Article ; Online: Morphometric Analysis of the Nucleus Accumbens Using the Mulligan Staining Method.

Oldoni, Carolina / Luz Veronez, Djanira Aparecida da / Piedade, Guilherme Santos / Santos, Emanuel Cassou Dos / Almeida, Daniel Benzecry de / Meneses, Murilo Sousa de

World neurosurgery

2018 Volume 118, Page(s) e223–e228

Abstract: Background: There is a need to further anatomically describe the nucleus accumbens (NA), as there is a growing neurosurgical interest in this locus but a limited understanding of its structure. In this study, we evaluated quantitative NA parameters and ... ...

Abstract	Background: There is a need to further anatomically describe the nucleus accumbens (NA), as there is a growing neurosurgical interest in this locus but a limited understanding of its structure. In this study, we evaluated quantitative NA parameters and spatial relationships with adjacent structures found in the telencephalon. Methods: A total of 155 NA specimens from coronal sections and 3 NA specimens from transverse sections were stained using the Mulligan technique as modified by Barnard et al. The distance from the NA to other structures was then measured. Results: The mean radius of the 155 NAs in the coronal sections was 6.23 ± 0.964 mm, averaging 8.99 ± 2.02 mm from midline (coordinate x), 27.09 ± 3.15 mm from the insula, 12.95 ± 3.21 mm from the outer border of the putamen, 10.52 ± 2.66 mm from the upper border of the caudate, and 8.84 ± 2.93 mm from the midline of the lateral ventricle. The mean distance from the NA center of gravity to the middle of the intercommissural line parallel to the midline (coordinate y) was 17.08 ±3.61 mm, and the mean vertical distance from the intercommissural line to the NA was 8.12 ± 1.265 mm. Conclusions: We obtained the stereotactic coordinates of (x, y, z) = (8, 17, -8) for the NA. From this and other delineations of the described position of the NA, it is possible to contribute to stereotactic surgical atlases, improving neurosurgical interventions in this structure.
MeSH term(s)	Humans ; Nucleus Accumbens/chemistry ; Nucleus Accumbens/pathology ; Nucleus Accumbens/surgery ; Staining and Labeling/methods ; Stereotaxic Techniques
Language	English
Publishing date	2018-06-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2018.06.163
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Article ; Online: Morphometric Study of the Internal Globus Pallidus Using the Robert, Barnard, and Brown Staining Method.

Dos Santos, Emanuel Cassou / da Luz Veronez, Djanira Aparecida / de Almeida, Daniel Benzecry / Piedade, Guilherme Santos / Oldoni, Carolina / de Meneses, Murilo Sousa / Marques, Mayara Silva

World neurosurgery

2019 Volume 126, Page(s) e371–e378

Abstract: Background: The globus pallidus internus (Gpi) is a major target in functional neurosurgery. Anatomical studies are crucial for correct planning and good surgical outcomes in this region. The present study described the anatomical coordinates of the Gpi ...

Abstract	Background: The globus pallidus internus (Gpi) is a major target in functional neurosurgery. Anatomical studies are crucial for correct planning and good surgical outcomes in this region. The present study described the anatomical coordinates of the Gpi and its relationship with other brain structures and compared the findings with those from previous anatomical studies. Methods: We obtained 35 coronal and 5 horizontal brain specimens from the Department of Anatomy and stained them using the Robert, Barnard, and Brown technique. After excluding defective samples, 60 nuclei were analyzed by assessing their distances to the anatomical references and the trajectories to these nuclei. Results: The barycenter of the Gpi was identified at the level of the mammillary bodies and 1 cm above the intercommissural plane. Thereafter, the distances to other structures were found. The mean ± standard deviation distance was 15.62 ± 2.66 mm to the wall of the third ventricle and 17.02 ± 2.69 mm to its midline, 4.74 ± 1.12 mm to the optic tract, 2.51 ± 0.8 mm and 13.56 ± 2 mm to the internal and external capsule, and 21.3 ± 2.44 mm to the insular cortex. The cortical point of entry should be located 22.03 ± 4.34 mm to 48.74 ± 4.44 mm from the midline. Conclusion: The Gpi has less variability in distance to closer anatomical references, such as the optic tract and internal capsule. Distant locations showed a more inhomogeneous pattern. Anatomical studies such as ours are important for the development of new therapeutic approaches and can be used as a basis for new research involving volumetric and specific group analyses.
MeSH term(s)	Cadaver ; Globus Pallidus/anatomy & histology ; Humans ; Staining and Labeling/methods
Language	English
Publishing date	2019-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2019.02.059
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Article ; Online: Perfil do paciente com dor crônica atendido em um ambulatório de dor de uma grande cidade do sul do Brasil

Anderson Cipriano / Daniel Benzecry de Almeida / Janaina Vall

Revista Dor, Vol 12, Iss 4, Pp 297-

2011 Volume 300

Abstract: JUSTIFICATIVA E OBJETIVOS: Dor crônica afeta aproximadamente 30% da população mundial e a sua epidemiologia ainda é pouco descrita no Brasil. O objetivo deste estudo foi identificar o perfil dos pacientes com dor crônica que procuram atendimento num ... ...

Abstract	JUSTIFICATIVA E OBJETIVOS: Dor crônica afeta aproximadamente 30% da população mundial e a sua epidemiologia ainda é pouco descrita no Brasil. O objetivo deste estudo foi identificar o perfil dos pacientes com dor crônica que procuram atendimento num ambulatório de dor na cidade de Curitiba. MÉTODO: Estudo descritivo transversal retrospectivo, que incluiu 111 pacientes com queixas de dor crônica atendidos no ambulatório de dor do Instituto de Neurologia de Curitiba (INC). RESULTADOS: A maioria dos pacientes foi do sexo feminino, com idade entre 40 e 49 anos e casada. A profissão mais prevalente foram os autônomos que englobam as atividades de cozinheiro, cabeleireiro, vendedor, mecânico, arquiteto, advogado, entre outras. Mesmo com dor, a maioria dos pacientes continuava trabalhando, sendo que alguns vinham de cidades localizadas fora do estado. Entre as dores crônicas a mais prevalente foi a lombalgia, seguida de dor nos membros inferiores, cervicalgia, membros superiores, dor generalizada, cefaleia e dor orofacial. CONCLUSÃO: A dor crônica foi mais prevalente na população feminina e a dor mais prevalente no estudo foi a lombalgia.
Keywords	Dor ; Dor lombar ; Epidemiologia ; Medicine ; R ; Medicine (General) ; R5-920
Language	English
Publishing date	2011-12-01T00:00:00Z
Publisher	Sociedade Brasileira para o Estudo da Dor
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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