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  1. Article: Percutaneous CT-Guided Biopsy of the Craniovertebral Junction: Safety, Diagnostic Yield, and Technical Notes.

    Spinnato, Paolo / Rimondi, Eugenio / Facchini, Giancarlo

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 1

    Abstract: The craniovertebral junction defined as the occiput, the atlas, and the axis is a complex bony region that contains vital neural and vascular structures. We report the experience of a single academic institution regarding CT-guided biopsy of this ... ...

    Abstract The craniovertebral junction defined as the occiput, the atlas, and the axis is a complex bony region that contains vital neural and vascular structures. We report the experience of a single academic institution regarding CT-guided biopsy of this skeletal region. We reviewed all of the CT-guided biopsies performed in our department, completed in the craniovertebral junction. We collected data in regard to biopsy procedures, patients' vital statistics, and histopathological diagnosis. In total, 16 patients (8M and 8F; mean age 52; range 16-86 years old) were included in this series. In eight patients, the lesions were located in the atlas vertebra (8/16-50%), in six patients in the axis (37.5%), and in two patients in the occiput (12.5%). No complications were observed during or after the procedures. All of the procedures were technically successful. The biopsy was diagnostic in 13/16 patients (81.3%): four metastatic lesions (25%-three breast and one prostate cancers), four multiple myeloma bone lesions (25%), three aneurismal bone cysts (18.8%), one aggressive hemangioma (6.3%), and one pseudogout (6.3%). Moreover, in two-thirds (66.6%) of non-diagnostic histological reports, malignancies were excluded. CT-guided percutaneous biopsy is a safe tool and allows obtaining a histological diagnosis, in most cases, even in the most delicate site of the human skeleton-the craniovertebral junction.
    Language English
    Publishing date 2022-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12010168
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  2. Article ; Online: Percutaneous CT-Guided Biopsy of the Craniovertebral Junction

    Paolo Spinnato / Eugenio Rimondi / Giancarlo Facchini

    Diagnostics, Vol 12, Iss 168, p

    Safety, Diagnostic Yield, and Technical Notes

    2022  Volume 168

    Abstract: The craniovertebral junction defined as the occiput, the atlas, and the axis is a complex bony region that contains vital neural and vascular structures. We report the experience of a single academic institution regarding CT-guided biopsy of this ... ...

    Abstract The craniovertebral junction defined as the occiput, the atlas, and the axis is a complex bony region that contains vital neural and vascular structures. We report the experience of a single academic institution regarding CT-guided biopsy of this skeletal region. We reviewed all of the CT-guided biopsies performed in our department, completed in the craniovertebral junction. We collected data in regard to biopsy procedures, patients’ vital statistics, and histopathological diagnosis. In total, 16 patients (8M and 8F; mean age 52; range 16–86 years old) were included in this series. In eight patients, the lesions were located in the atlas vertebra (8/16—50%), in six patients in the axis (37.5%), and in two patients in the occiput (12.5%). No complications were observed during or after the procedures. All of the procedures were technically successful. The biopsy was diagnostic in 13/16 patients (81.3%): four metastatic lesions (25%—three breast and one prostate cancers), four multiple myeloma bone lesions (25%), three aneurismal bone cysts (18.8%), one aggressive hemangioma (6.3%), and one pseudogout (6.3%). Moreover, in two-thirds (66.6%) of non-diagnostic histological reports, malignancies were excluded. CT-guided percutaneous biopsy is a safe tool and allows obtaining a histological diagnosis, in most cases, even in the most delicate site of the human skeleton—the craniovertebral junction.
    Keywords bone neoplasms ; image-guided biopsy ; atlanto-axial joint ; atlanto-occipital joint ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Can artificial intelligence replace endoscopists when assessing mucosal healing in ulcerative colitis? A systematic review and diagnostic test accuracy meta-analysis.

    Rimondi, Alessandro / Gottlieb, Klaus / Despott, Edward J / Iacucci, Marietta / Murino, Alberto / Tontini, Gian Eugenio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  

    Abstract: Backgrounds and aims: Mucosal healing (MH) in inflammatory bowel diseases (IBD) is an important landmark for clinical decision making. Artificial intelligence systems (AI) that automatically deliver the grade of endoscopic inflammation may solve ... ...

    Abstract Backgrounds and aims: Mucosal healing (MH) in inflammatory bowel diseases (IBD) is an important landmark for clinical decision making. Artificial intelligence systems (AI) that automatically deliver the grade of endoscopic inflammation may solve moderate interobserver agreement and the need of central reading in clinical trials.
    Methods: We performed a systematic review of EMBASE and MEDLINE databases up to 01/12/2022 following PRISMA and the Joanna Briggs Institute methodologies to answer the following question: "Can AI replace endoscopists when assessing MH in IBD?". The research was restricted to ulcerative colitis (UC), and a diagnostic odds ratio (DOR) meta-analysis was performed. Risk of bias was evaluated with QUADAS-2 tool.
    Results: A total of 21 / 739 records were selected for full text evaluation, and 12 were included in the meta-analysis. Deep learning algorithms based on convolutional neural networks architecture achieved a satisfactory performance in evaluating MH on UC, with sensitivity, specificity, DOR and SROC of respectively 0.91(CI95 %:0.86-0.95);0.89(CI95 %:0.84-0.93);92.42(CI95 %:54.22-157.53) and 0.957 when evaluating fixed images (n = 8) and 0.86(CI95 %:0.75-0.93);0.91(CI95 %:0.87-0.94);70.86(CI95 %:24.63-203.86) and 0.941 when evaluating videos (n = 6). Moderate-high levels of heterogeneity were noted, limiting the quality of the evidence.
    Conclusions: AI systems showed high potential in detecting MH in UC with optimal diagnostic performance, although moderate-high heterogeneity of the data was noted. Standardised and shared AI training may reduce heterogeneity between systems.
    Language English
    Publishing date 2023-12-05
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.11.005
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  4. Article ; Online: Water-immersion and cap-assisted endoscopic ablation of hemorrhagic radiation proctopathy with a novel 1.9/1.5-μm dual-emission endoscopic laser treatment.

    Tontini, Gian Eugenio / Rimondi, Alessandro / Cavallaro, Flaminia / Nandi, Nicoletta / Scaramella, Lucia / Vecchi, Maurizio / Elli, Luca

    Endoscopy

    2023  Volume 55, Issue S 01, Page(s) E338–E339

    MeSH term(s) Humans ; Immersion ; Rectum ; Rectal Diseases/surgery ; Hemorrhage ; Lasers
    Language English
    Publishing date 2023-01-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1981-2072
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  5. Article ; Online: Jejunal necrosis following caustic (NH3) ingestion in patient with total gastrectomy.

    Nandi, Nicoletta / Rimondi, Alessandro / Tontini, Gian Eugenio / Vecchi, Maurizio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2021  Volume 54, Issue 9, Page(s) 1269

    MeSH term(s) Burns, Chemical ; Caustics ; Eating ; Gastrectomy ; Humans ; Necrosis
    Chemical Substances Caustics
    Language English
    Publishing date 2021-06-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2021.04.034
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  6. Article ; Online: An Extremely Rare, Atypical and Genetically-undetermined Form of Osteopetrosis.

    Tetta, Cecilia / Focaccia, Marco / Bono, Lea / Rimondi, Eugenio / Spinnato, Paolo

    Current medical imaging

    2021  Volume 17, Issue 8, Page(s) 1036–1039

    Abstract: Introduction: Osteopetrosis is an uncommon skeletal disorder characterized by generalized sclerosis of bones due to defective osteoclast function. A wide variation in clinical severity of the disease has been observed. Radiographic features and genetic ... ...

    Abstract Introduction: Osteopetrosis is an uncommon skeletal disorder characterized by generalized sclerosis of bones due to defective osteoclast function. A wide variation in clinical severity of the disease has been observed. Radiographic features and genetic testing are commonly used to diagnose the condition.
    Case presentation: In the present study, we present a case of an extremely rare, atypical and genetically- undetermined form of Osteopetrosis.
    Conclusion: This patient had some clinical and radiological features of craniometaphyseal dysplasia along with atypical radiological signs of osteopetrosis.
    MeSH term(s) Bone and Bones ; Humans ; Osteoclasts ; Osteopetrosis/diagnostic imaging ; Radiography
    Language English
    Publishing date 2021-01-28
    Publishing country United Arab Emirates
    Document type Case Reports ; Journal Article
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/1573405617666210129111339
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  7. Article ; Online: Treatment options for gastrointestinal bleeding blue rubber bleb nevus syndrome: Systematic review.

    Rimondi, Alessandro / Sorge, Andrea / Murino, Alberto / Nandi, Nicoletta / Scaramella, Lucia / Vecchi, Maurizio / Tontini, Gian Eugenio / Elli, Luca

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

    2023  Volume 36, Issue 2, Page(s) 162–171

    Abstract: Objectives: Blue rubber bleb nevus syndrome (BRBNS) is a rare challenging cause of gastrointestinal bleeding. We performed a systematic review of case reports and case series on BRBNS to gather information on the treatment options currently available.!## ...

    Abstract Objectives: Blue rubber bleb nevus syndrome (BRBNS) is a rare challenging cause of gastrointestinal bleeding. We performed a systematic review of case reports and case series on BRBNS to gather information on the treatment options currently available.
    Methods: All studies reporting a case of BRBNS in humans were evaluated. Papers were ruled out if CARE criteria and explanations on patient's selection, ascertainment, causality, and reporting were not respected or identified. PROSPERO 2021 CRD 42021286982.
    Results: Blue rubber bleb nevus syndrome was treated in 106 cases from 76 reports. 57.5% of the population was under 18 years old, and up to 50% of the cases reported a previous treatment. Clinical success was achieved in 98 patients (92.4%). Three main types of interventions were identified: systemic drug therapy, endoscopy, and surgery. After BRBNS recurrence or previous therapy failure, systemic drug therapy emerged as a preferred second-line treatment over endoscopy (P = 0.01), but with a higher rate of reported adverse events when compared with surgery and endoscopy (P < 0.001). Endoscopic treatment was associated with a higher number of required sessions to achieve complete eradication when compared with surgery (P < 0.001). No differences between the three main areas were found in the overall follow-up time (P = 0.19) or in the recurrence rate (P = 0.45).
    Conclusion: Endoscopy, surgery, and systemic drug therapy are feasible treatment options for BRBNS. Systemic drug therapy was the favorite second-line treatment after endoscopic failure or recurrence of BRBNS, but adverse events were more frequently reported.
    MeSH term(s) Humans ; Adolescent ; Skin Neoplasms/diagnosis ; Gastrointestinal Neoplasms/complications ; Gastrointestinal Neoplasms/surgery ; Gastrointestinal Hemorrhage/diagnosis ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/therapy ; Nevus, Blue/complications ; Nevus, Blue/diagnosis ; Syndrome
    Language English
    Publishing date 2023-05-09
    Publishing country Australia
    Document type Systematic Review ; Case Reports ; Journal Article
    ZDB-ID 1171589-3
    ISSN 1443-1661 ; 0915-5635
    ISSN (online) 1443-1661
    ISSN 0915-5635
    DOI 10.1111/den.14564
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    Zs.A 3854: Show issues Location:
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  8. Article ; Online: Dual emission laser treatment and argon plasma coagulation in small bowel vascular lesion ablation: a pilot study.

    Tontini, Gian Eugenio / Rimondi, Alessandro / Scaramella, Lucia / Topa, Matilde / Penagini, Roberto / Vecchi, Maurizio / Elli, Luca

    Lasers in medical science

    2022  Volume 37, Issue 9, Page(s) 3749–3752

    MeSH term(s) Argon Plasma Coagulation ; Pilot Projects ; Intestine, Small ; Laser Coagulation ; Lasers ; Argon
    Chemical Substances Argon (67XQY1V3KH)
    Language English
    Publishing date 2022-07-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 632808-8
    ISSN 1435-604X ; 0268-8921
    ISSN (online) 1435-604X
    ISSN 0268-8921
    DOI 10.1007/s10103-022-03608-x
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    Zs.A 2148: Show issues Location:
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  9. Article ; Online: Endoscopy during the COVID-19 pandemic: Is it time to down-grade personal protective equipment for vaccinated personnel?

    Elli, Luca / Rimondi, Alessandro / Tontini, Eugenio / Gori, Andrea / Vecchi, Maurizio / Penagini, Roberto

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2021  Volume 53, Issue 7, Page(s) 801–802

    MeSH term(s) COVID-19/prevention & control ; COVID-19/transmission ; COVID-19 Vaccines ; Endoscopy, Digestive System ; Humans ; Infection Control ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Italy ; Pandemics ; Personal Protective Equipment
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-04-27
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2021.04.023
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  10. Article ; Online: A Mass With High Uptake of Fluorodeoxyglucose on Positron Emission Tomography.

    Staals, Eric L / Rimondi, Eugenio / Palmerini, Emanuela

    JAMA oncology

    2018  Volume 4, Issue 10, Page(s) 1421–1422

    MeSH term(s) Adolescent ; Ankle Joint/diagnostic imaging ; Diagnosis, Differential ; Female ; Fluorodeoxyglucose F18 ; Humans ; Magnetic Resonance Imaging/methods ; Positron-Emission Tomography/methods ; Reproducibility of Results ; Sensitivity and Specificity ; Synovitis, Pigmented Villonodular/diagnostic imaging
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2018-10-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2018.1120
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