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  1. Article ; Online: Assessing the impact of immobilisation on the bioavailability of PFAS to plants in contaminated Australian soils.

    Biek, Sali Khair / Khudur, Leadin S / Rigby, Laura / Singh, Navneet / Askeland, Matthew / Ball, Andrew S

    Environmental science and pollution research international

    2024  Volume 31, Issue 13, Page(s) 20330–20342

    Abstract: Per- and polyfluoroalkyl substances (PFAS) have become a key concern to both environmental and human health due to their extreme persistence in the environment and their ability to bioaccumulate in plants, animals, and humans. In this mesocosm study, ... ...

    Abstract Per- and polyfluoroalkyl substances (PFAS) have become a key concern to both environmental and human health due to their extreme persistence in the environment and their ability to bioaccumulate in plants, animals, and humans. In this mesocosm study, Australian PFAS-contaminated soil with a mean total concentration of 8.05 mg/kg and a mean combined PFHxS + PFOS concentration of 7.89 mg/kg was treated with an immobilisation sorbent (RemBind®) at different application rates (0.5, 1, 1.5, 2, 3, 4, and 5% w/w). To assess the efficacy of this immobilisation treatment, PFAS leachability, PFAS plant uptake, and ecotoxicity tests were conducted. Leachability testing was performed according to the Australian Standard Leaching Procedure (ASLP) at pH 5 and 7. A grass species (Dactylis glomerata) was used to measure plant uptake of PFAS from untreated and treated contaminated soil. In addition, the Microtox test was used to assess the associated ecotoxicity. The immobilisation treatment resulted in a significant reduction of 88.5-99.8% in the total PFAS leachability and 88.7-99.8% in the combined PFOS and PFHxS leachability at pH 5. Similarly, significant reductions (5-12-fold) were observed in the plant uptake of total PFAS and combined PFOS and PFHxS in all treated soil samples. In addition, although the Microtox test showed relatively low ecotoxicity in all the experimental samples, including the untreated soil, a significant decrease in the ecotoxicity of treated soil samples was observed. The results from this study highlight that this treatment approach has the potential to reduce both PFAS leachability and plant bioavailability with a relatively low associated ecotoxicity. This is likely to reduce the risk of the transfer of PFAS into higher trophic levels. This immobilisation treatment may, therefore, reduce the risk associated with PFAS-contaminated soils and may be an important remediation tool for managing certain PFAS-contaminated soils.
    MeSH term(s) Animals ; Humans ; Biological Availability ; Soil Pollutants/analysis ; Australia ; Plants ; Soil/chemistry ; Fluorocarbons
    Chemical Substances Soil Pollutants ; Soil ; Fluorocarbons
    Language English
    Publishing date 2024-02-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32496-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Associations of Use of Social Media and Psychopathology and Body Image in Pre- and Post-surgical Bariatric Samples: a Cross-sectional Analysis.

    Butt, Melissa / Su, Lilly / Rigby, Andrea

    Obesity surgery

    2022  Volume 32, Issue 9, Page(s) 3047–3055

    Abstract: Purpose: Interest has grown regarding the impact of social media platforms on mental health including body image and internalized weight bias (IWB) in those who have struggled with weight issues. However, few studies have addressed social media usage in ...

    Abstract Purpose: Interest has grown regarding the impact of social media platforms on mental health including body image and internalized weight bias (IWB) in those who have struggled with weight issues. However, few studies have addressed social media usage in bariatric patient samples. The objective of this study was to understand how the amount of time spent on social media could serve as a predictor for IWB in both pre- and post-operative bariatric patients.
    Materials and methods: Pre- and post-operative patients at one academic medical center completed self-report measures assessing patients' IWB, depression, anxiety, body dissatisfaction, sociodemographic variables, and social media usage. Data were collected from March 2019 to April 2020. Statistical methods that included correlations, logistical regression models, and ANOVA analysis were used to determine the relationship between time spent on social media and other covariates.
    Results: A total of 148 responses were collected from the pre-surgical population, with 81 responses from the post-surgical sample. At baseline, the majority of respondents used social media for approximately 1 h per day (n = 37; 27.82%). Time spent on social media was negatively associated with age (r =  - 0.24 [- 0.40, - 0.08]), and positively associated with IWB (r = 0.20 [0.02, 0.36]) and anxiety (r = 0.21 [0.01, 0.39]). In the post-operative group, only the 6-month BMI (r = 0.29 [0.05, 0.49]) was positively associated with time spent on social media.
    Conclusion: Given this study's findings, providers are encouraged to become aware of patients' use of social media, and to understand the impact social media usage can have on the mental well-being of patients.
    MeSH term(s) Bariatric Surgery/psychology ; Bariatrics ; Body Image/psychology ; Cross-Sectional Studies ; Humans ; Mental Disorders ; Obesity, Morbid/surgery ; Social Media
    Language English
    Publishing date 2022-07-15
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-022-06206-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The impact of spatially varying wetland source signatures on the atmospheric variability of

    Stell, Angharad C / Douglas, Peter M J / Rigby, Matthew / Ganesan, Anita L

    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

    2021  Volume 379, Issue 2210, Page(s) 20200442

    Abstract: We present the first spatially resolved distribution of the [Formula: see text] signature of wetland methane emissions and assess its impact on atmospheric [Formula: see text]. The [Formula: see text] signature map is derived by relating [Formula: see ... ...

    Abstract We present the first spatially resolved distribution of the [Formula: see text] signature of wetland methane emissions and assess its impact on atmospheric [Formula: see text]. The [Formula: see text] signature map is derived by relating [Formula: see text] of precipitation to measured [Formula: see text] of methane wetland emissions at a variety of wetland types and locations. This results in strong latitudinal variation in the wetland [Formula: see text] source signature. When [Formula: see text] is simulated in a global atmospheric model, little difference is found in global mean, inter-hemispheric difference and seasonal cycle if the spatially varying [Formula: see text] source signature distribution is used instead of a globally uniform value. This is because atmospheric [Formula: see text] is largely controlled by OH fractionation. However, we show that despite these small differences, using atmospheric records of [Formula: see text] to infer changes in the wetland emissions distribution requires the use of the more accurate spatially varying [Formula: see text] source signature. We find that models will only be sensitive to changes in emissions distribution if spatial information can be exploited through the spatially resolved source signatures. In addition, we also find that on a regional scale, at sites measuring excursions of [Formula: see text] from background levels, substantial differences are simulated in atmospheric [Formula: see text] if using spatially varying or uniform source signatures. This article is part of a discussion meeting issue 'Rising methane: is warming feeding warming? (part 1)'.
    Language English
    Publishing date 2021-09-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 208381-4
    ISSN 1471-2962 ; 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
    ISSN (online) 1471-2962
    ISSN 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
    DOI 10.1098/rsta.2020.0442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sustained growth of sulfur hexafluoride emissions in China inferred from atmospheric observations.

    An, Minde / Prinn, Ronald G / Western, Luke M / Zhao, Xingchen / Yao, Bo / Hu, Jianxin / Ganesan, Anita L / Mühle, Jens / Weiss, Ray F / Krummel, Paul B / O'Doherty, Simon / Young, Dickon / Rigby, Matthew

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1997

    Abstract: Sulfur hexafluoride ( ... ...

    Abstract Sulfur hexafluoride (SF
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-46084-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Improving comprehensive emergency obstetric and newborn care in Tanzania: A qualitative study.

    Mselle, Lilian / O'Hearn, Shawna / Aston, Megan / Murphy, Gail Tomblin / Rigby, Janet

    Midwifery

    2023  Volume 123, Page(s) 103698

    Abstract: Aim: The purpose of this qualitative study was to explore how health care professionals, managers and community members experienced the implementation of a training program in comprehensive emergency obstetric and neonatal care training in rural ... ...

    Abstract Aim: The purpose of this qualitative study was to explore how health care professionals, managers and community members experienced the implementation of a training program in comprehensive emergency obstetric and neonatal care training in rural Tanzania.
    Background: Given the high rates of maternal and newborn mortality in Tanzania, the government committed to improving maternal health by increasing access to health care; improving reproductive, maternal, newborn health; reducing maternal and neonate mortality; and increasing the number of public health centers with emergency obstetric and neonatal care. To address the gap in emergency obstetric and neonatal care amongst the health workforce, five health care facilities in rural Tanzania participated in a 3-month specialized training program. The training was geared to increase access to skilled deliveries, prevent maternal and neonate deaths, and reduce referrals to district hospitals.
    Methods: Twenty-four focus group discussions were held with members of Council Health Management Team, Health Facility Management Team, staff who received training, and community members. Data collection and analysis was guided by content analysis and the World Health Organization's availability, accessibility, acceptability, and quality framework.
    Findings: Participants reported acquiring necessary skills that enabled them to provide quality and safe obstetric and newborn care. Five themes emerged from the analysis 1) competent and confident health care teams, 2) renewed commitment to teamwork, 3) community confidence and trust in the health team, 4) mentorship as a critical element of success, and 5) enhancing training and practice. These five emerging themes demonstrate enhanced confidence and trust by the community and increased competency of health care teams to support mothers through pregnancy and birth at the health centre.
    Conclusion: The competencies acquired by health care providers demonstrate an increase in staff commitment and teamwork. There is an increased number of deliveries in health centres, a declining trend of maternal and neonate deaths and referrals to other health centres because the health care providers are capable of competently and confidently providing emergency obstetric and neonatal care services.
    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Tanzania ; Parturition ; Qualitative Research ; Maternal Health Services ; Mothers ; Delivery, Obstetric ; Health Services Accessibility
    Language English
    Publishing date 2023-04-19
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 1036567-9
    ISSN 1532-3099 ; 0266-6138
    ISSN (online) 1532-3099
    ISSN 0266-6138
    DOI 10.1016/j.midw.2023.103698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiorespiratory Interactions in Paediatrics: 'It's (almost always) the circulation stupid!'

    Rigby, M L / Rosenthal, M

    Paediatric respiratory reviews

    2017  Volume 22, Page(s) 60–65

    Abstract: The interaction of the heart and lungs is probably the most important aspect of life and survival. Fortunately, it is not difficult to understand the fundamentals. The purpose of the lungs and their ventilation is to present oxygen to the circulation via ...

    Abstract The interaction of the heart and lungs is probably the most important aspect of life and survival. Fortunately, it is not difficult to understand the fundamentals. The purpose of the lungs and their ventilation is to present oxygen to the circulation via the alveoli and to receive carbon dioxide from the circulation and then expel it. The relations of the heart and lungs and the matching of blood flow to the various organs with ventilation and lung perfusion may be disrupted by a variety of congenital or acquired heart malformations. They include those giving rise to an increased or reduced pulmonary blood flow, elevated pulmonary venous pressure or external physical pressure on the airways or lung parenchyma. Respiratory disorders which compromise cardiac function include states with reduced alveolar ventilation, those with a barrier to ventilation or perfusion, ventilation/perfusion mismatch and pulmonary vascular disease. There is also a fascinating group in which congenital disorders of the heart and lung co-exist to produce very particular modes of abnormal cardiopulmonary interaction.
    MeSH term(s) Abnormalities, Multiple/physiopathology ; Bronchopulmonary Dysplasia/physiopathology ; Cardiovascular Diseases/physiopathology ; Cerebral Palsy/physiopathology ; Child ; Child, Preschool ; Down Syndrome/complications ; Down Syndrome/physiopathology ; Humans ; Hypertension, Pulmonary/complications ; Hypertension, Pulmonary/physiopathology ; Infant ; Lung/abnormalities ; Lung/physiopathology ; Lung Diseases/physiopathology ; Neuromuscular Diseases/physiopathology ; Pulmonary Circulation/physiology ; Pulmonary Valve/abnormalities ; Pulmonary Ventilation/physiology ; Scimitar Syndrome/physiopathology ; Sleep Apnea, Obstructive/physiopathology ; Stenosis, Pulmonary Vein/physiopathology
    Language English
    Publishing date 2017-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2147664-0
    ISSN 1526-0550 ; 1526-0542
    ISSN (online) 1526-0550
    ISSN 1526-0542
    DOI 10.1016/j.prrv.2016.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Haemostatic devices in parotid surgery: a systematic review.

    Allen, L / MacKay, C / Rigby, M H / Trites, J / Taylor, S M

    The Journal of laryngology and otology

    2021  Volume 135, Issue 10, Page(s) 848–854

    Abstract: Objective: The Harmonic Scalpel and Ligasure (Covidien) devices are commonly used in head and neck surgery. Parotidectomy is a complex and intricate surgery that requires careful dissection of the facial nerve. This study aimed to compare surgical ... ...

    Abstract Objective: The Harmonic Scalpel and Ligasure (Covidien) devices are commonly used in head and neck surgery. Parotidectomy is a complex and intricate surgery that requires careful dissection of the facial nerve. This study aimed to compare surgical outcomes in parotidectomy using these haemostatic devices with traditional scalpel and cautery.
    Method: A systematic review of the literature was performed with subsequent meta-analysis of seven studies that compared the use of haemostatic devices to traditional scalpel and cautery in parotidectomy. Outcome measures included: temporary facial paresis, operating time, intra-operative blood loss, post-operative drain output and length of hospital stay.
    Results: A total of 7 studies representing 675 patients were identified: 372 patients were treated with haemostatic devices, and 303 patients were treated with scalpel and cautery. Statistically significant outcomes favouring the use of haemostatic devices included operating time, intra-operative blood loss and post-operative drain output. Outcome measures that did not favour either treatment included facial nerve paresis and length of hospital stay.
    Conclusion: Overall, haemostatic devices were found to reduce operating time, intra-operative blood loss and post-operative drain output.
    MeSH term(s) Blood Loss, Surgical/statistics & numerical data ; Dissection/adverse effects ; Drainage/trends ; Electrocoagulation/adverse effects ; Facial Nerve/surgery ; Facial Paralysis/epidemiology ; Female ; Hemostasis, Surgical/instrumentation ; Humans ; Length of Stay/statistics & numerical data ; Male ; Meta-Analysis as Topic ; Middle Aged ; Operative Time ; Outcome Assessment, Health Care ; Parotid Gland/surgery ; Postoperative Period ; Surgical Instruments/adverse effects
    Language English
    Publishing date 2021-08-23
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215121001973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Glial Cell-Axonal Growth Cone Interactions in Neurodevelopment and Regeneration.

    Rigby, Michael J / Gomez, Timothy M / Puglielli, Luigi

    Frontiers in neuroscience

    2020  Volume 14, Page(s) 203

    Abstract: The developing nervous system is a complex yet organized system of neurons, glial support cells, and extracellular matrix that arranges into an elegant, highly structured network. The extracellular and intracellular events that guide axons to their ... ...

    Abstract The developing nervous system is a complex yet organized system of neurons, glial support cells, and extracellular matrix that arranges into an elegant, highly structured network. The extracellular and intracellular events that guide axons to their target locations have been well characterized in many regions of the developing nervous system. However, despite extensive work, we have a poor understanding of how axonal growth cones interact with surrounding glial cells to regulate network assembly. Glia-to-growth cone communication is either direct through cellular contacts or indirect through modulation of the local microenvironment via the secretion of factors or signaling molecules. Microglia, oligodendrocytes, astrocytes, Schwann cells, neural progenitor cells, and olfactory ensheathing cells have all been demonstrated to directly impact axon growth and guidance. Expanding our understanding of how different glial cell types directly interact with growing axons throughout neurodevelopment will inform basic and clinical neuroscientists. For example, identifying the key cellular players beyond the axonal growth cone itself may provide translational clues to develop therapeutic interventions to modulate neuron growth during development or regeneration following injury. This review will provide an overview of the current knowledge about glial involvement in development of the nervous system, specifically focusing on how glia directly interact with growing and maturing axons to influence neuronal connectivity. This focus will be applied to the clinically-relevant field of regeneration following spinal cord injury, highlighting how a better understanding of the roles of glia in neurodevelopment can inform strategies to improve axon regeneration after injury.
    Language English
    Publishing date 2020-03-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2020.00203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: In Situ Observations of Halogenated Gases at the Shangdianzi Background Station and Emission Estimates for Northern China.

    Yi, Liying / An, Minde / Yu, Haibo / Ma, Zhiqiang / Xu, Lin / O'Doherty, Simon / Rigby, Matthew / Western, Luke M / Ganesan, Anita L / Zhou, Liyan / Shi, Qingfeng / Hu, Yunxing / Yao, Bo / Xu, Weiguang / Hu, Jianxin

    Environmental science & technology

    2023  Volume 57, Issue 18, Page(s) 7217–7229

    Abstract: Halogenated gases include ozone-depleting substances and greenhouse gases, such as chlorofluorocarbons, halons, hydrochlorofluorocarbons, hydrofluorocarbons, and perfluorinated gases. In situ atmospheric observations of major halogenated gases were ... ...

    Abstract Halogenated gases include ozone-depleting substances and greenhouse gases, such as chlorofluorocarbons, halons, hydrochlorofluorocarbons, hydrofluorocarbons, and perfluorinated gases. In situ atmospheric observations of major halogenated gases were conducted at the Shangdianzi (SDZ) background station, China, from October 2020 to September 2021 using ODS5-pro, a newly developed measurement system. The measurement time series of 36 halogenated gases showed occasional pollution events, where background conditions represented 25% (CH
    MeSH term(s) Air Pollutants/analysis ; Carbon Dioxide ; Environmental Monitoring/methods ; China ; Ozone
    Chemical Substances Air Pollutants ; Carbon Dioxide (142M471B3J) ; Ozone (66H7ZZK23N)
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.3c00695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Monitoring calf circumference: changes during prolonged constrained sitting.

    Rigby, Laura / Frey, Mona / Alexander, Kara-Lyn / De Carvalho, Diana

    Ergonomics

    2021  Volume 65, Issue 4, Page(s) 631–641

    Abstract: Prolonged sitting has been associated with negative health effects; however, short-term time-varying exposure and response data is lacking. Twenty-two young and healthy participants were seated for ... ...

    Abstract Prolonged sitting has been associated with negative health effects; however, short-term time-varying exposure and response data is lacking. Twenty-two young and healthy participants were seated for 2
    MeSH term(s) Electromyography ; Humans ; Leg/physiology ; Muscle, Skeletal ; Pain Measurement ; Posture/physiology
    Language English
    Publishing date 2021-09-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1920-3
    ISSN 1366-5847 ; 0014-0139
    ISSN (online) 1366-5847
    ISSN 0014-0139
    DOI 10.1080/00140139.2021.1979660
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