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  1. Article ; Online: ENT Telephone Clinics During the Coronavirus Pandemic: An Analysis of 400 Telephone Consultations at a District General Hospital.

    Sargsyan, Narek / Karunaratne, Dilhara / Masani, Alisha / Howell, Lauren / Yousif, Madi

    Ear, nose, & throat journal

    2021  Volume 102, Issue 11, Page(s) 733–738

    Abstract: Background: The COVID-19 pandemic led to the introduction of telephone consultations in order to provide specialist health care remotely. This study analyses the outcomes of ear, nose, and throat (ENT) telephone consultations.: Methods: Retrospective ...

    Abstract Background: The COVID-19 pandemic led to the introduction of telephone consultations in order to provide specialist health care remotely. This study analyses the outcomes of ear, nose, and throat (ENT) telephone consultations.
    Methods: Retrospective analysis was undertaken of 400 ENT telephone consultations.
    Results: All 2-week-wait neck or face lump patients underwent imaging and 78% were successfully discharged. 80% of vertigo patients and 100% of 2-week-wait throat symptom patients were offered face-to-face consultations. All primary hyperparathyroidism patients were managed remotely, being discharged, or with telephone follow-up. The majority of routine referrals were managed without the need for face-to-face consultation.
    Conclusion: Vertigo patients and 2-week-wait throat symptom patients should be offered a face-to-face consultation in the first instance. For patients with neck or face lumps, initial referral for imaging may improve patient flow and facilitate safe discharge. It is appropriate to continue with telephone consultations for all other patient groups.
    MeSH term(s) Humans ; Referral and Consultation ; Pandemics ; Pharynx ; Retrospective Studies ; Hospitals, General ; Telephone ; Vertigo ; Telemedicine/methods
    Language English
    Publishing date 2021-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613211028091
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  2. Article ; Online: Assessment of Safety of Remdesivir in Covid - 19 Patients with Estimated Glomerular Filtration Rate (eGFR) < 30 ml/min per 1.73 m^2.

    Wang, Shan / Huynh, Christy / Islam, Shahidul / Malone, Brian / Masani, Naveed / Joseph, D'Andrea

    Journal of intensive care medicine

    2021  Volume 37, Issue 6, Page(s) 764–768

    Abstract: Purpose: Safety of remdesivir in patients with renal impairment is unknown. Incidence of liver injury secondary to remdesivir is also unknown. The objective of this study is to assess the incidence of acute kidney injury (AKI) and to trend the liver ... ...

    Abstract Purpose: Safety of remdesivir in patients with renal impairment is unknown. Incidence of liver injury secondary to remdesivir is also unknown. The objective of this study is to assess the incidence of acute kidney injury (AKI) and to trend the liver enzymes during remdesivir treatment and change in eGFR from baseline to end of treatment as well as 48 h post completion of remdesivir therapy.
    Methods: This is a retrospective chart review study including adult patients admitted with COVID-19 receiving remdesivir with a baseline eGFR < 30 ml/min per 1.73 m^2 from December 2020 to May 2021. The primary outcome was to assess the incidence of AKI and hepatic injury. The secondary outcome was to assess the efficacy of remdesivir defined by change in oxygen requirement.
    Results: Seventy-one patients were included in the study. Patients experienced an improvement in eGFR from baseline (T0) to end of remdesivir treatment (T1), as well as 48 h after the end of the treatment (T2) ( + 30.3% and + 30.6% respectively, P < .0001). Creatinine reduced from baseline (T0) to T1 and T2 (-20.9% and -20.5% respectively, P < .0001). Creatinine clearance improved from baseline to T1 and T2 ( + 26.6% and + 26.2% respectively, p < .0001). Elevation of aminotransferase (AST) was observed at T1 ( + 2.5%, P  =  .727), however, AST reduction was seen at T2 (-15.8%, P  =  .021). Elevation in alanine transaminase (ALT) was observed at T1 and T2 ( + 25% and + 12%, P  =  .004 and P  =  .137 respectively). Both direct and total bilirubin remained stable and were not significantly changed from baseline.
    Conclusion: Our study showed that remdesivir use in renally-impaired patients with eGFR < 30 ml/min is safe. Remdesivir may be considered as a therapeutic option in this population with COVID-19 infection.
    MeSH term(s) Acute Kidney Injury/etiology ; Adenosine Monophosphate/analogs & derivatives ; Adult ; Alanine/analogs & derivatives ; COVID-19/drug therapy ; Creatinine ; Female ; Glomerular Filtration Rate ; Humans ; Male ; Retrospective Studies
    Chemical Substances remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Creatinine (AYI8EX34EU) ; Alanine (OF5P57N2ZX)
    Language English
    Publishing date 2021-12-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/08850666211070521
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  3. Article ; Online: A 61-Year-Old Man With Membranoproliferative Glomerulonephritis.

    Daccueil, Farah / Masani, Naveed N / D'Agati, Vivette D / Shirazian, Shayan

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2017  Volume 70, Issue 6, Page(s) A16–A20

    MeSH term(s) Biopsy ; Diagnosis, Differential ; Glomerulonephritis, Membranoproliferative/diagnosis ; Humans ; Kidney Glomerulus/pathology ; Male ; Middle Aged
    Language English
    Publishing date 2017-11-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2017.08.004
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    Zs.MO 468: Show issues

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  4. Article ; Online: Protoplast Isolation and Transformation in Oil Palm.

    Masani, Mat Yunus Abdul / Parveez, Ghulam Kadir Ahmad / Noll, Gundula / Fizree, M D Piji Mohd Al Akmarul / Sambanthamurthi, Ravigadevi / Pruefer, Dirk

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2464, Page(s) 187–202

    Abstract: The protocol outlined in this chapter describes a detailed procedure for protoplast isolation and transformation using polyethylene glycol (PEG)-mediated transfection and DNA microinjection, highlighting also the critical steps associated with the method. ...

    Abstract The protocol outlined in this chapter describes a detailed procedure for protoplast isolation and transformation using polyethylene glycol (PEG)-mediated transfection and DNA microinjection, highlighting also the critical steps associated with the method. Briefly, we will describe the efficient isolation of protoplasts from 3-month-old suspension calli collected at 14 days after cultured. Digestion of the calli with an optimal composition of enzyme solution yielded over 2 × 10
    MeSH term(s) DNA/genetics ; DNA/metabolism ; Microinjections ; Polyethylene Glycols/metabolism ; Protoplasts/metabolism ; Transfection
    Chemical Substances Polyethylene Glycols (3WJQ0SDW1A) ; DNA (9007-49-2)
    Language English
    Publishing date 2022-03-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2164-6_14
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  5. Article ; Online: Should target hemoglobin levels in dialysis patients be lowered to 9-10 g/dl?

    Fishbane, Steven / Masani, Naveed N / Hazzan, Azzour D

    Seminars in dialysis

    2014  Volume 27, Issue 3, Page(s) 282–284

    MeSH term(s) Anemia/blood ; Anemia/drug therapy ; Anemia/etiology ; Erythropoietin/analogs & derivatives ; Erythropoietin/therapeutic use ; Hemoglobins/metabolism ; Humans ; Renal Dialysis/adverse effects
    Chemical Substances Hemoglobins ; Erythropoietin (11096-26-7)
    Language English
    Publishing date 2014-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1028193-9
    ISSN 1525-139X ; 0894-0959
    ISSN (online) 1525-139X
    ISSN 0894-0959
    DOI 10.1111/sdi.12211
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    Zs.A 2879: Show issues Location:
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  6. Article: Acute Tubular Necrosis in a Patient With Myeloma Treated With Carfilzomib.

    Liberman, Vladimir / D'Agati, Vivette D / Masani, Naveed N / Drakakis, James / Mattana, Joseph

    Kidney international reports

    2016  Volume 1, Issue 2, Page(s) 89–92

    Language English
    Publishing date 2016-06-23
    Publishing country United States
    Document type Case Reports
    ISSN 2468-0249
    ISSN 2468-0249
    DOI 10.1016/j.ekir.2016.06.002
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  7. Article ; Online: Transoesophageal echocardiography in adult congenital heart disease.

    Masani, N D

    Heart (British Cardiac Society)

    2001  Volume 86 Suppl 2, Page(s) II30–II40

    MeSH term(s) Adult ; Echocardiography, Doppler, Color/methods ; Echocardiography, Transesophageal/methods ; Heart Atria/diagnostic imaging ; Heart Defects, Congenital/diagnostic imaging ; Heart Septal Defects, Atrial/diagnostic imaging ; Heart Septal Defects, Ventricular/diagnostic imaging ; Humans ; Pulmonary Veins/abnormalities ; Pulmonary Veins/diagnostic imaging ; Transposition of Great Vessels/diagnostic imaging ; Transposition of Great Vessels/surgery
    Language English
    Publishing date 2001-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heart.86.suppl_2.ii30
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    Zs.MO 112: Show issues

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  8. Article ; Online: Pleural, pancreatic and prostatic involvement in IgG4-related disease mimicking pancreatic head malignancy.

    Foley, Robert W / Redman, Stewart L / Graham, Richard N / Phull, Jaspal S / Masani, Vidan / Colleypriest, Benjamin J / Little, David

    BJR case reports

    2020  Volume 6, Issue 2, Page(s) 20190110

    Abstract: We describe the case of a gentleman with pleural thickening. On follow-up imaging, dilatation of the main pancreatic and common biliary ducts was noted and an initial diagnosis of pancreatic malignancy was made. During his preoperative workup for ... ...

    Abstract We describe the case of a gentleman with pleural thickening. On follow-up imaging, dilatation of the main pancreatic and common biliary ducts was noted and an initial diagnosis of pancreatic malignancy was made. During his preoperative workup for pancreatic head malignancy, a PET-CT was performed, which demonstrated increased uptake in the pancreas, in the pleura and in the prostate gland. This raised the possibility of immunoglobulin G4-related disease (IgG4-RD), which was effectively treated with oral steroids. IgG4-RD is a well-described cause of autoimmune pancreatitis but can affect other regions, including the pleura and prostate. It is essential that radiologists are aware of the imaging findings in IgG4-RD and can direct clinicians towards this important multisystem diagnosis.
    Language English
    Publishing date 2020-09-29
    Publishing country England
    Document type Case Reports
    ISSN 2055-7159
    ISSN (online) 2055-7159
    DOI 10.1259/bjrcr.20190110
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  9. Article ; Online: Update on membranoproliferative GN.

    Masani, Naveed / Jhaveri, Kenar D / Fishbane, Steven

    Clinical journal of the American Society of Nephrology : CJASN

    2014  Volume 9, Issue 3, Page(s) 600–608

    Abstract: Membranoproliferative GN represents a pattern of injury seen on light microscopy. Historically, findings on electron microscopy have been used to further subclassify this pathologic entity. Recent advances in understanding of the underlying pathobiology ... ...

    Abstract Membranoproliferative GN represents a pattern of injury seen on light microscopy. Historically, findings on electron microscopy have been used to further subclassify this pathologic entity. Recent advances in understanding of the underlying pathobiology have led to a proposed classification scheme based on immunofluorescence findings. Dysregulation of the complement system has been shown to be a major risk factor for the development of a membranoproliferative GN pattern of injury on kidney biopsy. Evaluation and treatment of this complex disorder rest on defining the underlying mechanisms.
    MeSH term(s) Biomarkers/analysis ; Biopsy ; Fluorescent Antibody Technique ; Glomerulonephritis, Membranoproliferative/diagnosis ; Glomerulonephritis, Membranoproliferative/immunology ; Glomerulonephritis, Membranoproliferative/therapy ; Humans ; Kidney Glomerulus/immunology ; Kidney Glomerulus/pathology ; Predictive Value of Tests ; Recurrence ; Treatment Outcome
    Chemical Substances Biomarkers
    Language English
    Publishing date 2014-01-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.06410613
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  10. Article ; Online: Changes to the end-stage renal disease quality incentive program.

    Fishbane, Steven / Miller, Ilene / Wagner, John D / Masani, Naveed N

    Kidney international

    2012  Volume 81, Issue 12, Page(s) 1167–1171

    Abstract: Monitoring the quality of dialysis care has long been a component of the Medicare ESRD program. As part of the 2008 Medicare Improvements for Patients and Providers Act (MIPPA), Congress mandated the Quality Incentive Program (QIP), which linked measures ...

    Abstract Monitoring the quality of dialysis care has long been a component of the Medicare ESRD program. As part of the 2008 Medicare Improvements for Patients and Providers Act (MIPPA), Congress mandated the Quality Incentive Program (QIP), which linked measures of care quality to payments. The legislation embraced the idea that this linkage of federal money to performance would encourage the purchase of greater 'value.' The first 2 program years for the QIP use a simple scoring methodology and a limited scope of quality metrics. For payment year 2014 (performance period calendar year 2012), the program changes substantially, with an expanded number of quality measures and a more complex scoring methodology. In this article, we describe the program structure, quality measures, scoring system, and financial impact.
    MeSH term(s) Benchmarking/economics ; Centers for Medicare and Medicaid Services (U.S.)/economics ; Centers for Medicare and Medicaid Services (U.S.)/legislation & jurisprudence ; Centers for Medicare and Medicaid Services (U.S.)/standards ; Delivery of Health Care/economics ; Delivery of Health Care/legislation & jurisprudence ; Delivery of Health Care/standards ; Financing, Government ; Government Regulation ; Health Care Costs ; Health Policy/economics ; Humans ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/economics ; Kidney Failure, Chronic/therapy ; Outcome and Process Assessment (Health Care)/economics ; Outcome and Process Assessment (Health Care)/legislation & jurisprudence ; Outcome and Process Assessment (Health Care)/standards ; Practice Guidelines as Topic ; Program Development ; Quality Improvement/economics ; Quality Improvement/legislation & jurisprudence ; Quality Improvement/standards ; Quality Indicators, Health Care/economics ; Quality Indicators, Health Care/legislation & jurisprudence ; Quality Indicators, Health Care/standards ; Reimbursement, Incentive/legislation & jurisprudence ; Reimbursement, Incentive/standards ; Renal Dialysis/economics ; Renal Dialysis/standards ; Treatment Outcome ; United States
    Language English
    Publishing date 2012-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1038/ki.2012.138
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