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  1. Article ; Online: ABO-Incompatible Heart Transplantation: Where Science, Society, and Policy Collide.

    Milligan, Caitlin / Daly, Kevin P

    Journal of cardiac failure

    2023  Volume 30, Issue 3, Page(s) 486–487

    MeSH term(s) Humans ; Heart Failure ; Heart Transplantation ; Policy ; ABO Blood-Group System ; Graft Survival ; Graft Rejection
    Chemical Substances ABO Blood-Group System
    Language English
    Publishing date 2023-08-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detecting and managing cardiac allograft vasculopathy within the transition from pediatric to adult heart transplantation care: Lighting the pathway ahead.

    Vest, Amanda R / Daly, Kevin P

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2023  Volume 43, Issue 2, Page(s) 238–240

    MeSH term(s) Adult ; Humans ; Child ; Lighting ; Heart Transplantation ; Coronary Disease/diagnosis ; Heart Diseases ; Allografts
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2023.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The ABO-incompatible paradigm shifts only as far as allocation policy allows.

    Daly, Kevin P

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2020  Volume 39, Issue 7, Page(s) 636–638

    MeSH term(s) ABO Blood-Group System ; Blood Group Incompatibility ; Child ; Child, Preschool ; Heart Transplantation ; Humans ; Policy
    Chemical Substances ABO Blood-Group System
    Language English
    Publishing date 2020-04-25
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2020.04.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Burden of Pediatric Heart Failure That Lies Just Under the Surface.

    Daly, Kevin P / Zuckerman, Warren A

    Journal of the American College of Cardiology

    2022  Volume 79, Issue 19, Page(s) 1929–1931

    MeSH term(s) Child ; Heart Defects, Congenital ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy ; Humans
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.03.339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Experience with live attenuated varicella vaccination in pediatric heart transplant recipients: Considering a new path forward.

    Daly, Kevin P / Sharma, Tanvi S

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2022  Volume 41, Issue 8, Page(s) 1027–1028

    MeSH term(s) Chickenpox/prevention & control ; Child ; Heart Transplantation ; Herpesvirus 3, Human ; Humans ; Transplant Recipients ; Vaccination
    Language English
    Publishing date 2022-05-13
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2022.03.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Managing risk of surgical procedures in pediatric transplant recipients taking mTOR inhibitors: What is the optimal strategy?

    Daly, Kevin P

    Pediatric transplantation

    2018  Volume 22, Issue 1

    MeSH term(s) Calcineurin Inhibitors ; Child ; Humans ; Immunosuppressive Agents ; Kidney Transplantation ; TOR Serine-Threonine Kinases ; Transplant Recipients
    Chemical Substances Calcineurin Inhibitors ; Immunosuppressive Agents ; MTOR protein, human (EC 2.7.1.1) ; TOR Serine-Threonine Kinases (EC 2.7.1.1)
    Language English
    Publishing date 2018
    Publishing country Denmark
    Document type Editorial ; Comment
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.13136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Finding the correct role for heart transplant in the treatment of hypoplastic left heart syndrome.

    Daly, Kevin P

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2016  Volume 35, Issue 3, Page(s) 299–300

    MeSH term(s) Heart Transplantation ; Humans ; Hypoplastic Left Heart Syndrome
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2016.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Impact of a positive crossmatch on pediatric heart transplant outcomes.

    Milligan, Caitlin / Williams, Ryan J / Singh, Tajinder P / Bastardi, Heather J / Esteso, Paul / Almond, Christopher S / Gauvreau, Kimberlee / Daly, Kevin P

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2024  

    Abstract: Background: Pediatric heart transplant (HT) candidates experience high waitlist mortality due to a limited donor pool that is constrained in part by anti-HLA sensitization. We evaluated the impact of CDC and Flow donor-specific crossmatch (XM) results ... ...

    Abstract Background: Pediatric heart transplant (HT) candidates experience high waitlist mortality due to a limited donor pool that is constrained in part by anti-HLA sensitization. We evaluated the impact of CDC and Flow donor-specific crossmatch (XM) results on pediatric HT outcomes.
    Methods: All pediatric HTs between 1999 and 2019 in the OPTN database were included. Donor-specific XM results were sub-categorized based on CDC and Flow results. Primary outcomes were treated rejection in the first year and time to death or allograft loss. Propensity scores were utilized to adjust for differences in baseline characteristics.
    Results: A total of 4,695 pediatric HT patients with T-cell XM data were included. After propensity score adjustment, a positive T-cell CDC-XM was associated with 2 times higher odds of treated rejection (OR 2.29 (1.56, 3.37)) and shorter time to death/allograft loss (HR 1.50 (1.19, 1.88)) compared to a negative Flow-XM. HT recipients who were Flow-XM positive with negative/unknown CDC-XM did not have higher odds of rejection or shorter time to death/allograft loss. An isolated positive B-cell XM was also not associated with worse outcomes. Over the study period XM testing shifted from CDC- to Flow-based assays.
    Conclusions: A positive donor-specific T-cell CDC-XM was associated with rejection and death/allograft loss following pediatric HT. This association was not observed with a positive T-cell Flow-XM or B-cell XM result alone. The shift away from performing the CDC-XM may result in loss of important prognostic information unless the clinical relevance of quantitative Flow-XM results on heart transplant outcomes is systematically studied.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2024.02.1457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Circulating donor-derived cell-free DNA: a true biomarker for cardiac allograft rejection?

    Daly, Kevin P

    Annals of translational medicine

    2015  Volume 3, Issue 4, Page(s) 47

    Language English
    Publishing date 2015-03-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.3978/j.issn.2305-5839.2015.01.35
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Major structure-activity relationships of resolvins, protectins, maresins and their analogues.

    Daly, Kevin / O'Sullivan, Killian / O'Sullivan, Timothy P

    Future medicinal chemistry

    2022  

    Abstract: Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation. They are termed specialized proresolving mediators and facilitate a return to homeostasis ... ...

    Abstract Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation. They are termed specialized proresolving mediators and facilitate a return to homeostasis following an inflammatory response. These molecules are currently the focus of intensive investigation, primarily for their ability to suppress inflammation in chronic disease states. Researchers have employed different synthetic approaches to assess whether various structural modifications of these compounds could provide access to future therapeutics. This review summarizes the modifications made thus far and focuses on the key structure-activity relationships which have been uncovered for resolvins, protectins, maresins and their analogues.
    Language English
    Publishing date 2022-11-30
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1756-8927
    ISSN (online) 1756-8927
    DOI 10.4155/fmc-2022-0206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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