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  1. Article: A rare case of congenital lobar emphysema diagnosed in a 13-year-old boy.

    Matuszczak, Ewa / Dębek, Wojciech

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2021  Volume 17, Issue 4, Page(s) 205–207

    Language English
    Publishing date 2021-01-15
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2020.102331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A rare case of congenital lobar emphysema diagnosed in a 13-year-old boy

    Ewa Matuszczak / Wojciech Dębek

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 17, Iss 4, Pp 205-

    2021  Volume 207

    Keywords Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Situation of Pediatric Patients with Testicular Torsion in Times of COVID-19.

    Komarowska, Marta / Kowalska, Małgorzata / Grubczak, Kamil / Pawelczyk, Alicja / Hermanowicz, Adam / Debek, Wojciech / Matuszczak, Ewa

    Emergency medicine international

    2023  Volume 2023, Page(s) 9960452

    Abstract: Purpose: To assess whether the COVID-19 pandemic had an influence on presentation of testicular torsion and/or increase in the frequency of orchiectomy. ...

    Abstract Purpose: To assess whether the COVID-19 pandemic had an influence on presentation of testicular torsion and/or increase in the frequency of orchiectomy.
    Language English
    Publishing date 2023-05-08
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2596429-X
    ISSN 2090-2859 ; 2090-2840
    ISSN (online) 2090-2859
    ISSN 2090-2840
    DOI 10.1155/2023/9960452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Infantile Hemangiomas: An Update on Pathogenesis and Treatment.

    Kowalska, Małgorzata / Dębek, Wojciech / Matuszczak, Ewa

    Journal of clinical medicine

    2021  Volume 10, Issue 20

    Abstract: Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different ... ...

    Abstract Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different treatment methods. Although most infantile hemangiomas require only active observation because of their natural course, which results in involution, about 10% present with complications that require immediate treatment. The basic treatment includes systemic and topical options. In cases of insufficient response or rebound growth, other forms of treatment should be considered. In some cases, combined therapy might be initiated.
    Language English
    Publishing date 2021-10-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10204631
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  5. Article ; Online: Infantile Hemangiomas

    Małgorzata Kowalska / Wojciech Dębek / Ewa Matuszczak

    Journal of Clinical Medicine, Vol 10, Iss 4631, p

    An Update on Pathogenesis and Treatment

    2021  Volume 4631

    Abstract: Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different ... ...

    Abstract Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different treatment methods. Although most infantile hemangiomas require only active observation because of their natural course, which results in involution, about 10% present with complications that require immediate treatment. The basic treatment includes systemic and topical options. In cases of insufficient response or rebound growth, other forms of treatment should be considered. In some cases, combined therapy might be initiated.
    Keywords infantile hemangioma ; propranolol ; PDL ; Medicine ; R
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Is Testicular Torsion a Real Problem in Pediatric Patients With Cryptorchidism?

    Komarowska, Marta Diana / Pawelczyk, Alicja / Matuszczak, Ewa / Dębek, Wojciech / Hermanowicz, Adam

    Frontiers in pediatrics

    2021  Volume 8, Page(s) 575741

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2021-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2020.575741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: UCHL1, besides leptin and fibronectin, also could be a sensitive marker of the relapsing-remitting type of multiple sclerosis.

    Górska, Ewelina / Tylicka, Marzena / Hermanowicz, Adam / Matuszczak, Ewa / Sankiewicz, Anna / Gorodkiewicz, Ewa / Hermanowicz, Justyna / Karpińska, Elżbieta / Socha, Katarzyna / Kochanowicz, Jan / Jakoniuk, Marta / Kamińska, Joanna / Homšak, Evgenija / Koper-Lenkiewicz, Olga Martyna

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 3423

    Abstract: Research on the markers of immunoregulatory response in multiple sclerosis (MS) is still of great importance. The aim of our study was the evaluation of leptin, fibronectin, and UCHL1 concentrations as potential biomarkers of a relapsing-remitting type ... ...

    Abstract Research on the markers of immunoregulatory response in multiple sclerosis (MS) is still of great importance. The aim of our study was the evaluation of leptin, fibronectin, and UCHL1 concentrations as potential biomarkers of a relapsing-remitting type of MS (RRMS). Surface Plasmon Resonance Imaging (SPRI) biosensors were used for the evaluation of proteins concentrations in 100 RRMS patients and 46 healthy volunteers. Plasma leptin, fibronectin, and UCHL1 concentrations were significantly higher in RRMS patients compared to the control group (p < 0.001, respectively). UCHL1 concentration evaluation revealed the highest diagnostic sensitivity (100%) and negative predictive value (100%) in differentiating MS patients from healthy individuals. There was no significant difference in the UCHL1 concentrations depending on the patient's sex, the presence of relapse within the last 24 months, and the EDSS value (p > 0.05, respectively). In RRMS patients UCHL1 concentration positively correlated with fibronectin levels (r = 0.3928; p < 0.001). In the current cohort of patients plasma UCHL1 concentration was independent of the time of MS relapse and the severity of neurological symptoms. Thus current study may indicate that plasma UCHL1, besides leptin and fibronectin, also could be a promising high-sensitive potential biomarker of relapsing-remitting type of MS. However, these results should be validated with a larger group of patients, taking into account neuroimaging and cerebrospinal fluid analysis data, and by comparing them to patients with other neurological diseases as a control group.
    MeSH term(s) Humans ; Multiple Sclerosis/diagnosis ; Fibronectins ; Leptin ; Health Status ; Healthy Volunteers ; Ubiquitin Thiolesterase
    Chemical Substances Fibronectins ; Leptin ; UCHL1 protein, human ; Ubiquitin Thiolesterase (EC 3.4.19.12)
    Language English
    Publishing date 2023-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-30237-3
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  8. Article: The Impact of Bisphenol A on Fertility, Reproductive System, and Development: A Review of the Literature.

    Matuszczak, Ewa / Komarowska, Marta Diana / Debek, Wojciech / Hermanowicz, Adam

    International journal of endocrinology

    2019  Volume 2019, Page(s) 4068717

    Abstract: Bisphenol A (BPA) has been used since the 1950s, in food packaging, industrial materials, dental sealants, and personal hygiene products. Everyone is exposed to BPA through skin, inhalation, and digestive system. BPA disrupts endocrine pathways, because ... ...

    Abstract Bisphenol A (BPA) has been used since the 1950s, in food packaging, industrial materials, dental sealants, and personal hygiene products. Everyone is exposed to BPA through skin, inhalation, and digestive system. BPA disrupts endocrine pathways, because it has weak estrogenic, antiandrogenic, and antithyroid activities. Despite the rapid metabolism, BPA can accumulate in different tissues. Many researchers proved the impact of BPA on human development, metabolism, and finally reproductive system. There is increasing evidence that BPA has impact on human fertility and is responsible for the reproductive pathologies, e.g., testicular dysgenesis syndrome, cryptorchidism, cancers, and decreased fertility in male and follicle loss in female.
    Language English
    Publishing date 2019-04-10
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 2502951-4
    ISSN 1687-8345 ; 1687-8337
    ISSN (online) 1687-8345
    ISSN 1687-8337
    DOI 10.1155/2019/4068717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ubiquitin carboxy-terminal hydrolase L1 - physiology and pathology.

    Matuszczak, Ewa / Tylicka, Marzena / Komarowska, Marta Diana / Debek, Wojciech / Hermanowicz, Adam

    Cell biochemistry and function

    2020  Volume 38, Issue 5, Page(s) 533–540

    Abstract: Ubiquitin C-terminal hydrolase 1 (UCHL1) is an enzyme unique for its multiple activity - both ligase and hydrolase. UCHL1 was first identified as an abundant protein found in the brain and testes, however its expression is not limited to the neuronal ... ...

    Abstract Ubiquitin C-terminal hydrolase 1 (UCHL1) is an enzyme unique for its multiple activity - both ligase and hydrolase. UCHL1 was first identified as an abundant protein found in the brain and testes, however its expression is not limited to the neuronal compartment. UCHL1 is also highly expressed in carcinomas of various tissue origins, including those from brain, lung, breast, kidney, colon, prostate, pancreas and mesenchymal tissues. Loss-of-function studies and an inhibitor for UCHL1 confirmed the importance of UCHL1 for cancer therapy. So far biological significance of UCHL1 was described in the following processes: spermatogenesis, oncogenesis, angiogenesis, cell proliferation and differentiation in skeletal muscle, inflammation, tissue injury, neuronal injury and neurodegeneration.
    MeSH term(s) Cell Differentiation ; Cell Proliferation ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Neurons/metabolism ; Neurons/pathology ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism
    Chemical Substances UCHL1 protein, human ; Ubiquitin Thiolesterase (EC 3.4.19.12)
    Language English
    Publishing date 2020-03-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 283643-9
    ISSN 1099-0844 ; 0263-6484
    ISSN (online) 1099-0844
    ISSN 0263-6484
    DOI 10.1002/cbf.3527
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  10. Article: Traumatic pneumatocele in an 11-year-old boy - report of a rare case and review of the literature.

    Matuszczak, Ewa / Oksiuta, Marzanna / Hermanowicz, Adam / Dębek, Wojciech

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2017  Volume 14, Issue 1, Page(s) 59–62

    Abstract: The authors present a case of a pneumatocele associated with blunt trauma in a child. An 11-year-old boy was admitted to the emergency department after he was knocked over and his chest was trapped under a soccer goal. Chest computed tomography (CT) ... ...

    Abstract The authors present a case of a pneumatocele associated with blunt trauma in a child. An 11-year-old boy was admitted to the emergency department after he was knocked over and his chest was trapped under a soccer goal. Chest computed tomography (CT) revealed several cavities in the lobes of both lungs. The CT of the abdomen revealed traumatic laceration of the liver. The patient was treated conservatively. His condition was stable and subsequently improved. He was discharged 19 days later. After nine months, a chest radiograph showed complete resolution of the pneumatocele, and abdominal ultrasound demonstrated complete resolution of the liver hematoma. A traumatic pneumatocele is a benign lesion resulting from blunt chest trauma, usually in children and young adults, which typically requires only conservative treatment. The CT scanning is the most sensitive method for the detection of traumatic pneumatoceles. All emergency physicians should be familiar with the diagnosis and management of this condition, to avoid unnecessary invasive procedures.
    Language English
    Publishing date 2017-03-31
    Publishing country Poland
    Document type Case Reports
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2017.66934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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