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  1. Book ; Online ; E-Book: Alternating electric fields therapy in oncology

    Wong, Eric T.

    a practical guide to clinical applications of tumor treating fields

    2016  

    Author's details Eric T. Wong editor
    Keywords alternating electric fields therapy ; anti-cancer treatment ; glioblastomas ; neuro-oncology ; non-small cell lung cancer ; ovarian cancer ; pancreatic cancer
    Language English
    Size 1 Online-Ressource (xiv, 129 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019152397
    ISBN 978-3-319-30576-9 ; 9783319305745 ; 3-319-30576-X ; 3319305743
    DOI 10.1007/978-3-319-30576-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Technological advances in the treatment of cancer: combining modalities to optimize outcomes

    Wong, Eric T. / Toms, Steven A. / Ahluwalia, Manmeet S.

    (Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 11, supplement 11 (November 2015))

    2015  

    Author's details moderator Eric T. Wong, MD ; participants Steven A. Toms, MD; Manmeet S. Ahluwalia, MD
    Series title Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 11, supplement 11 (November 2015)
    Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Collection Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Language English
    Size 18 Seiten, Illustrationen, Diagramme
    Publisher Millennium Medical Publishing
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019338938
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Body Fluids Modulate Propagation of Tumor Treating Fields.

    Wong, Eric T / Lok, Edwin

    Advances in radiation oncology

    2023  Volume 9, Issue 1, Page(s) 101316

    Abstract: Tumor treating fields (TTFields) are nonionizing alternating electric fields that have anticancer properties. After the initial approval for use in patients with recurrent glioblastoma in 2011 and newly diagnosed glioblastomas in 2015, they are now being ...

    Abstract Tumor treating fields (TTFields) are nonionizing alternating electric fields that have anticancer properties. After the initial approval for use in patients with recurrent glioblastoma in 2011 and newly diagnosed glioblastomas in 2015, they are now being tested in those with advanced lung cancer, ovarian carcinoma, and pancreatic cancer. Unlike ionizing radiation therapy, TTFields have nonlinear propagation characteristics; therefore, it is difficult for clinicians to recognize intuitively the location where these fields have the most impact. However, finite element analysis offers a means of delineating TTFields in the human body. Our analyses in the brain, pelvis, and thorax revealed that cerebrospinal fluid, edema, urine, ascites, pleural fluid, and necrotic core within a tumor greatly influence their distribution within these body cavities. Our observations thus provided a unified framework on the role of these compartmentalized fluids in influencing the propagation of TTFields.
    Language English
    Publishing date 2023-07-22
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2023.101316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Governance of picture archiving and communications systems

    Tong, Carrison K. S. / Wong, Eric T. T.

    data security and quality management of filmless radiology

    2009  

    Author's details Carrison K.S. Tong ; Eric T.T. Wong
    Keywords Radiographic Image Interpretation, Computer-Assisted / methods ; Radiographic Image Interpretation, Computer-Assisted / instrumentation ; Image Processing, Computer-Assisted / methods ; Computer Security / standards ; Picture archiving and communication systems in medicine/Security measures ; Picture archiving and communication systems in medicine/Quality control
    Subject code 362.1770684
    Language English
    Size XIV, 350 S. : Ill., graph. Darst., 26cm
    Publisher Medical information science reference
    Publishing place Hershey, Pa. u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT015768495
    ISBN 978-1-59904-672-3 ; 1-59904-672-5
    Database Catalogue ZB MED Medicine, Health

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  5. Article: The effects of analytics capability and sensing capability on operations performance: the moderating role of data-driven culture.

    Wong, David T W / Ngai, Eric W T

    Annals of operations research

    2023  , Page(s) 1–36

    Abstract: Studies indicate that organizational capability is a key factor in operational performance, and that both sensing and analytics capabilities have a significant influence on operational performance. This study develops a framework to examine the impact of ...

    Abstract Studies indicate that organizational capability is a key factor in operational performance, and that both sensing and analytics capabilities have a significant influence on operational performance. This study develops a framework to examine the impact of organizational capability on operational performance, with a specific focus on the implementation of sensing and analytics capabilities. We combine strategic fit theory, the dynamic capability view, and the resource-based view to examine how micro, small, and medium enterprises (MSMEs) strategically integrate a data-driven culture (DDC) with their organizational capabilities to enhance operational performance. We carry out empirical research to investigate whether a DDC moderates the influence of organizational capability on operational performance. Structural equation modeling of survey data from 149 MSMEs reveals that both sensing and analytics capabilities have a positive impact on operational performance. The results also suggest that a DDC positively moderates the influence of organizational capability on operational performance. We discuss the theoretical and managerial implications of our findings, the limitations of the study, and opportunities for further research.
    Language English
    Publishing date 2023-03-05
    Publishing country United States
    Document type Journal Article
    ISSN 0254-5330
    ISSN 0254-5330
    DOI 10.1007/s10479-023-05241-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Advances in the management of chemotherapy-induced nausea and vomiting: new data from recent and ongoing trials

    Wong, Eric T. / Aapro, Matti S. / Schwartzberg, Lee S.

    (Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 10, supplement 10 (October 2015))

    2015  

    Author's details discussants Eric Roeland, MD; Matti S. Aapro, MD; Lee S. Schwartzberg, MD
    Series title Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 10, supplement 10 (October 2015)
    Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Collection Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Language English
    Size 14 Seiten, Diagramme
    Publisher Millennium Medical Publishing
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019339012
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Patient-Reported Outcomes for Ocular Myasthenia Gravis.

    Wong, Sui Hsien / Eggenberger, Eric R / Cornblath, Wayne T

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2022  Volume 43, Issue 4, Page(s) 356

    MeSH term(s) Humans ; Myasthenia Gravis/diagnosis ; Myasthenia Gravis/therapy ; Patient Reported Outcome Measures
    Language English
    Publishing date 2022-01-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000001511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A mathematical model for velocity-selective arterial spin labeling.

    Liu, Thomas T / Wong, Eric C / Bolar, Divya S / Chen, Conan / Barnes, Ryan S

    Magnetic resonance in medicine

    2024  Volume 91, Issue 4, Page(s) 1384–1403

    Abstract: Purpose: To present a theoretical framework that rigorously defines and analyzes key concepts and quantities for velocity selective arterial spin labeling (VSASL).: Theory and methods: An expression for the VSASL arterial delivery function is derived ...

    Abstract Purpose: To present a theoretical framework that rigorously defines and analyzes key concepts and quantities for velocity selective arterial spin labeling (VSASL).
    Theory and methods: An expression for the VSASL arterial delivery function is derived based on (1) labeling and saturation profiles as a function of velocity and (2) physiologically plausible approximations of changes in acceleration and velocity across the vascular system. The dependence of labeling efficiency on the amplitude and effective bolus width of the arterial delivery function is defined. Factors that affect the effective bolus width are examined, and timing requirements to minimize quantitation errors are derived.
    Results: The model predicts that a flow-dependent negative bias in the effective bolus width can occur when velocity selective inversion (VSI) is used for the labeling module and velocity selective saturation (VSS) is used for the vascular crushing module. The bias can be minimized by choosing a nominal labeling cutoff velocity that is lower than the nominal cutoff velocity of the vascular crushing module.
    Conclusion: The elements of the model are specified in a general fashion such that future advances can be readily integrated. The model can facilitate further efforts to understand and characterize the performance of VSASL and provide critical theoretical insights that can be used to design future experiments and develop novel VSASL approaches.
    MeSH term(s) Magnetic Resonance Angiography ; Spin Labels ; Arteries/diagnostic imaging ; Models, Theoretical ; Acceleration ; Cerebrovascular Circulation/physiology ; Blood Flow Velocity/physiology
    Chemical Substances Spin Labels
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605774-3
    ISSN 1522-2594 ; 0740-3194
    ISSN (online) 1522-2594
    ISSN 0740-3194
    DOI 10.1002/mrm.29935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Linking data-driven innovation to firm performance: a theoretical framework and case analysis.

    Wong, David T W / Ngai, Eric W T

    Annals of operations research

    2022  , Page(s) 1–20

    Abstract: This paper examines the impact of data-driven innovation (DDI) on firm performance, based on an exploratory case study of a manufacturing firm in China's textile and apparel industry. It explores the influence of various contextual variables on the firm' ... ...

    Abstract This paper examines the impact of data-driven innovation (DDI) on firm performance, based on an exploratory case study of a manufacturing firm in China's textile and apparel industry. It explores the influence of various contextual variables on the firm's DDI and suggests ways to enhance DDI and thereby firm performance. Extending the literature on DDI, the paper proposes and validates a theoretical framework that incorporates the influence of various contextual factors on firms' DDI. The findings show that (1) individual context is associated with DDI; (2) organizational context is associated with DDI; and (3) DDI is associated with firm performance. This paper extends our understanding of how firm performance can be improved through DDI and shows that DDI should match a firm's contextual environment.
    Supplementary information: The online version contains supplementary material available at 10.1007/s10479-022-05038-y.
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ISSN 0254-5330
    ISSN 0254-5330
    DOI 10.1007/s10479-022-05038-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Computational Analysis of Tumor Treating Fields for Non-Small Cell Lung Cancer in Full Thoracic Models.

    Lok, Edwin / Liang, Olivia / Malik, Talbia / Wong, Eric T

    Advances in radiation oncology

    2023  Volume 8, Issue 4, Page(s) 101203

    Abstract: Purpose: Tumor Treating Fields (TTFields) are alternating electric fields at 150 to 200 kHz that exert their anticancer effect by destroying tumor cells when they undergo mitosis. TTFields are currently being tested in patients with non-small cell lung ... ...

    Abstract Purpose: Tumor Treating Fields (TTFields) are alternating electric fields at 150 to 200 kHz that exert their anticancer effect by destroying tumor cells when they undergo mitosis. TTFields are currently being tested in patients with non-small cell lung cancer with advanced disease (NCT02973789) and those with brain metastasis (NCT02831959). However, the distribution of these fields within the thoracic compartment remains poorly understood.
    Methods and materials: Using positron emission tomography-computed tomography image data sets obtained from a series of 4 patients with poorly differentiated adenocarcinoma, the positron emission tomography-positive gross tumor volume (GTV), clinical target volume (CTV), and structures from the chest surface to the intrathoracic compartment were manually segmented, followed by 3-dimensional physics simulation and computational modeling using finite element analysis. Electric field-volume histograms, specific absorption rate-volume histograms, and current density-volume histograms were generated to produce plan quality metrics (95%, 50%, and 5% volumes) for quantitative comparisons between models.
    Results: Unlike other organs in the body, the lungs have a large volume of air, which has a very low electric conductivity value. Our comprehensive and individualized models demonstrated heterogeneity in electric field penetration to the GTVs with differences upwards of 200% and yielded a diverse range of TTFields distributions. Target contact with the conductive pleura intensified TTFields at the GTV and CTV. Furthermore, in a sensitivity analysis, varying electric conductivity and mass density of the CTV altered TTFields coverage to both the CTV and GTV.
    Conclusions: Personalized modeling is important to accurately estimate target coverage at the tumor volumes and surrounding normal tissue structures in the thorax.
    Language English
    Publishing date 2023-02-26
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2023.101203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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