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  1. Article: ERWIN: an E-region wind interferometer.

    Gault, W A / Brown, S / Moise, A / Liang, D / Sellar, G / Shepherd, G G / Wimperis, J

    Applied optics

    1996  Volume 35, Issue 16, Page(s) 2913–2922

    Abstract: ... remotely from Toronto for four winter seasons. Some examples of data are shown to illustrate ERWIN's ...

    Abstract A field-widened Michelson interferometer designed to measure upper atmospheric winds at three altitudes near the mesopause by using airglow emissions from O(1)S, OH, and O(2) is described. A very large path difference (11 cm) is used to suppress the fringes from the hot F-region emission of O(1)S and to facilitate accurate measurements. Field widening and thermal compensation are achieved over the large spectral range (557.7-866.0 nm) by the use of three types of glass in the interferometer's arms. The instrument was installed at Resolute Bay, Canada (74.3 N, 94.5 W), in November 1992 and has been operated remotely from Toronto for four winter seasons. Some examples of data are shown to illustrate ERWIN's performance.
    Language English
    Publishing date 1996-06-01
    Publishing country United States
    Document type Journal Article
    ISSN 1559-128X
    ISSN 1559-128X
    DOI 10.1364/AO.35.002913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Sterility of Mammalia under Confinement.

    Brown, Arthur Erwin

    The Journal of comparative medicine and surgery

    2022  Volume 2, Issue 1, Page(s) 28–36

    Language English
    Publishing date 2022-10-24
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Optimal designs of clinical studies in the context of their inclusion in systematic reviews.

    Brown, Erwin M

    The Journal of antimicrobial chemotherapy

    2021  Volume 76, Issue 10, Page(s) 2498–2500

    Abstract: In this article I focus on the designs of clinical studies that have a high likelihood of producing reliable findings and those that do not, but that are still being published in large numbers in scientific journals. The former category includes ... ...

    Abstract In this article I focus on the designs of clinical studies that have a high likelihood of producing reliable findings and those that do not, but that are still being published in large numbers in scientific journals. The former category includes randomized trials, controlled before-after studies and interrupted time series, while the latter category comprises non-randomized trials, uncontrolled before-after studies, case-control/cohort studies and other observational studies. This distinction is important, particularly when studies of inferior design are used in systematic reviews that inform clinical practice guidelines, thereby potentially exerting adverse effects on clinical practice. I also highlight the implications of failing to enrol adequate numbers of patients in clinical trials.
    MeSH term(s) Case-Control Studies ; Humans ; Interrupted Time Series Analysis ; Systematic Reviews as Topic
    Language English
    Publishing date 2021-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkab227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UK.

    Brown, Nicholas M / Brown, Erwin M

    The Journal of antimicrobial chemotherapy

    2021  Volume 76, Issue 6, Page(s) 1377–1378

    Abstract: The UK guidelines for the treatment of infections caused by MRSA have been updated and are published in JAC-Antimicrobial Resistance. The update reviews new evidence published since the previous UK guidelines were published over 10 years ago. It includes ...

    Abstract The UK guidelines for the treatment of infections caused by MRSA have been updated and are published in JAC-Antimicrobial Resistance. The update reviews new evidence published since the previous UK guidelines were published over 10 years ago. It includes evidence relating to antimicrobial agents that have been licensed since then for the treatment of Gram-positive bacterial infections including MRSA. It also considers the impact on treatment of the changing epidemiology of MRSA in the UK, especially relating to circulating community strains. A striking finding from the current literature review was the paucity of good quality evidence. The current guidelines therefore represent a hybrid of varying degrees of evidence and expert opinion. Where there was no new published evidence, we have retained some of the existing recommendations. We were unable to find strong evidence of the superior efficacy of newer agents compared with that of vancomycin.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/epidemiology ; United Kingdom ; Vancomycin/pharmacology ; Vancomycin/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU)
    Language English
    Publishing date 2021-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkab036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Optimizing outcomes in the management of acute exacerbations of chronic

    Brown, Erwin M.

    (The journal of antimicrobial chemotherapy ; 45, Topic 2)

    2000  

    Author's details ed. by Erwin M. Brown
    Series title The journal of antimicrobial chemotherapy ; 45, Topic 2
    Collection
    Language English
    Size V, 32 S. : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012014267
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Conference proceedings: Cefepime

    Brown, Erwin M.

    a beta-lactamase stable extended spectrum cephalosporin ; based on selected papers, some presented at the Sixth European Congress of Clinical Microbiology and Infectious Diseases, Seville, 28 - 31 March 1993

    (The journal of antimicrobial chemotherapy ; 32, Suppl. B)

    1993  

    Event/congress European Congress of Clinical Microbiology and Infectious Diseases (6, 1993, Sevilla)
    Author's details ed. by Erwin M. Brown
    Series title The journal of antimicrobial chemotherapy ; 32, Suppl. B
    Collection
    Keywords Cephalosporins / congresses
    Language English
    Size VI, 214 S. : graph. Darst.
    Publisher Acad. Press
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT006224151
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Conference proceedings: Cefpirome

    Brown, Erwin M.

    a novel extended spectrum cephalosporin ; based on presentations at the Seventeenth International Congress of Chemotherapy, Berlin, Germany, 23 - 28 June 1991

    (The journal of antimicrobial chemotherapy ; 29, Suppl. A)

    1992  

    Event/congress International Congress of Chemotherapy (17, 1991, Berlin)
    Author's details ed. by Erwin M. Brown
    Series title The journal of antimicrobial chemotherapy ; 29, Suppl. A
    Collection
    Keywords Cephalosporins / congresses
    Size VI, 104 S. : graph. Darst.
    Publisher Acad. Pr
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT004238056
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: Treatment of methicillin-resistant

    Brown, Nicholas M / Goodman, Anna L / Horner, Carolyne / Jenkins, Abi / Brown, Erwin M

    JAC-antimicrobial resistance

    2021  Volume 3, Issue 1, Page(s) dlaa114

    Abstract: These evidence-based guidelines are an updated version of those issued in 2008. They have been produced following a review of the published literature (2007-18) pertaining to the treatment of infections caused by MRSA. The guidelines update, where ... ...

    Abstract These evidence-based guidelines are an updated version of those issued in 2008. They have been produced following a review of the published literature (2007-18) pertaining to the treatment of infections caused by MRSA. The guidelines update, where appropriate, previous recommendations, taking into account changes in the UK epidemiology of MRSA, ongoing national surveillance data and the efficacy of novel anti-staphylococcal agents licensed for use in the UK. Emerging therapies that have not been licensed for use in the UK at the time of the review have also been assessed.
    Language English
    Publishing date 2021-02-03
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2632-1823
    ISSN (online) 2632-1823
    DOI 10.1093/jacamr/dlaa114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Ciprofloxacin

    Brown, Erwin M.

    defining its role today ; based on papers presented at a meeting, at Lucknam Park, Bath, 28 - 29 April 1990

    (The journal of antimicrobial chemotherapy ; 26, Suppl. F)

    1990  

    Author's details ed. by Erwin M. Brown
    Series title The journal of antimicrobial chemotherapy ; 26, Suppl. F
    Collection
    Keywords Ciprofloxacin / congresses
    Size VI, 193 S. : Ill., graph. Darst.
    Publisher Acad. Pr
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003701679
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: An evaluation of stakeholder engagement in comparative effectiveness research: lessons learned from SWOG S1415CD.

    Bell-Brown, Ari / Watabayashi, Kate / Kreizenbeck, Karma / Ramsey, Scott D / Bansal, Aasthaa / Barlow, William E / Lyman, Gary H / Hershman, Dawn L / Mercurio, Anne Marie / Segarra-Vazquez, Barbara / Kurttila, Florence / Myers, Jamie S / Golenski, John D / Johnson, Judy / Erwin, Robert L / Walia, Guneet / Crawford, Jeffrey / Sullivan, Sean D

    Journal of comparative effectiveness research

    2022  Volume 11, Issue 18, Page(s) 1313–1321

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Humans ; Comparative Effectiveness Research/methods ; Stakeholder Participation ; Patient Outcome Assessment
    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2669725-7
    ISSN 2042-6313 ; 2042-6305
    ISSN (online) 2042-6313
    ISSN 2042-6305
    DOI 10.2217/cer-2022-0158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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